Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC176740 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 EPHX2 1 24300 IC50 PMID: 24679441
NPC176740 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC256849 ADORA1 5 Median: 44900
Range: 44000 to 44900
Ki PMID: 21664729
PMID: 23602401
PMID: 24139167
PMID: 24139167
PMID: 24164628
NPC256849 ADORA2A 1 20472 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC256849 ADORA3 3 Median: 13300
Range: 13300 to 13300
Ki PMID: 12139454
PMID: 24139167
PMID: 24139167
NPC256849 ADORA2B 10 Median: 27150
Range: 10400 to 33800
Ki PMID: 12014951
PMID: 19569717
PMID: 19569717
PMID: 20188574
PMID: 20537438
PMID: 21664729
PMID: 24139167
PMID: 24139167
PMID: 24164628
PMID: 26824742
NPC256849 GDA 1 10200 Ki PMID: 20716488