Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC138113 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC13991 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC163984 ALDH1A1 2 Median: 25285.5
Range: 22387.2 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC186098 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC186098 HPGD 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP3A4 4 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 TP53 3 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP2D6 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 KDM4E 2 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP19A1 1 20700 IC50 PMID: 18558747
NPC228785 HPGD 2 Median: 24068.2
Range: 19952.6 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 MAPK1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 RELA 1 15900 IC50 PMID: 19839614
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC233267 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC233267 TDP1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC233267 HPGD 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC252067 TYR 1 50000 IC50 PMID: 14741268
NPC255042 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC257124 AR 2 Median: 19027.305
Range: 19000 to 19054.61
IC50 PMID: 20226658
PMID: 20226658
NPC264317 POLB 2 Median: 44925
Range: 43600 to 46250
IC50 PMID: 14640519
PMID: 18343122
NPC264317 GLI1 2 Median: 32000
Range: 32000 to 32000
IC50 PMID: 18842418
PMID: 19309080
NPC287331 RECQL 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288411 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288411 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288411 HPGD 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288411 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288411 MAPT 2 Median: 25285.5
Range: 22387.2 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC292792 PPARA 1 46500 EC50 PMID: 22381047
NPC292792 PPARG 1 40000 EC50 PMID: 22381047
NPC292792 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297358 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC67037 AKR1B1 1 19050 IC50 PMID: 22261024
NPC68889 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC71853 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC71853 ALOX15 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC192638 TOP2A 1 10400 IC50 PMID: 11754608
NPC257124 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 PTGS1 1 11000 IC50 PMID: 16038536
NPC264317 AKR1B1 1 11000 IC50 PMID: 21561086
NPC288411 NPSR1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC71853 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC71853 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC71853 ALOX12 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862