Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC186098 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC186098 HPGD 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC217226 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC235059 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC246693 THRB 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC246693 PTPN1 1 25000 IC50 PMID: 15050628
NPC246693 ALDH1A1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC256463 TOP1 1 44000 IC50 PMID: 7699697
NPC256463 SOAT2 1 28700 IC50 PMID: 17157006
NPC256463 SOAT1 1 22400 IC50 PMID: 17157006
NPC257124 AR 2 Median: 19027.305
Range: 19000 to 19054.61
IC50 PMID: 20226658
PMID: 20226658
NPC279026 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC279026 PPARD 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC279026 PPARA 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC279026 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC292792 PPARA 1 46500 EC50 PMID: 22381047
NPC292792 PPARG 1 40000 EC50 PMID: 22381047
NPC292792 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC299405 TOP1 1 45000 IC50 PMID: 7699697
NPC299405 TERT 1 37300 IC50 PMID: 11992780
NPC61 SRC 1 26000 IC50 PMID: 19427202
NPC61 THRB 2 Median: 34893.65
Range: 25118.9 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC61 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC61 LCK 2 Median: 39500
Range: 24000 to 55000
IC50 PMID: 14505648
PMID: 19427202
NPC61 BLM 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC61 JUN 1 16200 IC50 PMID: 24491635
NPC61 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC7491 CYP2C9 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC96835 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC96835 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99886 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99886 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC215008 AKT1 1 10980 IC50 PMID: 24321345
NPC257124 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 PTGS1 1 11000 IC50 PMID: 16038536
NPC259134 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC61 MAPT 3 Median: 14125.4
Range: 12589.3 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC7491 CYP2C19 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862