Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC305912 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC305912 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 SMN1;SMN2 2 Median: 35481.3
Range: 35481.3 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 THRB 7 Median: 39810.7
Range: 31622.8 to 50118.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 CYP2D6 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC68441 BLM 4 Median: 29903.3
Range: 28183.8 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 MAPK1 3 Median: 28183.8
Range: 25118.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 GALK1 1 23690.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC68441 TP53 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 BCL2L2 1 17700 Ki PMID: 17227711
NPC68441 CYP1A2 2 Median: 27829.825
Range: 15848.93 to 39810.72
AC50 PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 MAPT 15 Median: 25118.9
Range: 15848.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 CYP2C9 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC8466 TRPA1 1 16000 EC50 PMID: 20356305
NPC8466 MAPK1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC218357 SMN1;SMN2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC68441 NPSR1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC68441 CASP1 5 Median: 15848.9
Range: 12589.3 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 HTT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC68441 CASP7 3 Median: 15848.9
Range: 12589.3 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 ALDH1A1 2 Median: 25515.45
Range: 11220.2 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68441 KIF11 2 Median: 17900
Range: 10800 to 25000
IC50 PMID: 17095225
PMID: 23434636