Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC134764 CYP2D6 1 35500 IC50 PMID: 15679319
NPC138113 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC13991 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC150809 CYP3A4 1 28700 IC50 PMID: 15679319
NPC157944 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC157944 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC157944 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC157944 TDP1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC18205 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19890 CYP2D6 1 26500 IC50 PMID: 15679319
NPC19890 SLC6A1 1 20600 IC50 PMID: 24112084
NPC236522 CYP3A4 1 15000 IC50 PMID: 15679319
NPC255042 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC257124 AR 2 Median: 19027.305
Range: 19000 to 19054.61
IC50 PMID: 20226658
PMID: 20226658
NPC287331 RECQL 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC304079 ATM 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC304079 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC40352 CYP2D6 1 17500 IC50 PMID: 15679319
NPC47946 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC47946 ALOX15 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC49074 PTGS1 1 36000 IC50 PMID: 16038536
NPC68889 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC72796 CYP3A4 1 14900 IC50 PMID: 15679319
NPC7491 CYP2C9 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC134764 SLC6A3 1 12000 IC50 PMID: 24112084
NPC257124 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 PTGS1 1 11000 IC50 PMID: 16038536
NPC7491 CYP2C19 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99572 CYP3A4 1 13700 IC50 PMID: 15679319