Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC217226 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC230002 IMPDH2 2 Median: 20900
Range: 20900 to 20900
IC50 PMID: 3655795
PMID: 8133298
NPC254698 MAOA 3 Median: 40000
Range: 31800 to 56234.13
IC50 PMID: 20715818
PMID: 20934874
PMID: 21134756
NPC254698 MAOB 7 Median: 18750
Range: 18750 to 18750
IC50 PMID: 19926363
PMID: 20615716
PMID: 20715818
PMID: 21872365
PMID: 23153812
PMID: 24746464
DOI: 10.1039/C0MD00014K
NPC30691 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC42372 IMPDH2 1 22700 IC50 PMID: 16483769
NPC70744 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC70744 CA3 1 11100 Ki PMID: 20185318
NPC70744 CA4 1 10800 Ki PMID: 20185318
NPC70744 CA5B 1 10500 Ki PMID: 20185318