Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC174086 L3MBTL1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231149 MAPT 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231149 POLB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231149 TDP1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231149 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231149 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231149 KDM4E 2 Median: 30300.1
Range: 25118.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC231149 ALDH1A1 2 Median: 21450.85
Range: 17782.8 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC247553 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 AKR1B1 1 22900 IC50 PMID: 20805028
NPC247553 CASP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 CASP7 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 TDP1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 MAPT 2 Median: 33997.25
Range: 28183.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC73738 LMNA 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 NPSR1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 APEX1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC73738 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC8704 MMP2 1 23280 IC50 PMID: 22658537
NPC8704 MMP3 1 22300 IC50 PMID: 22658537
NPC8704 MMP9 1 21240 IC50 PMID: 22658537
NPC29883 CA2 2 Median: 10600
Range: 10600 to 10600
Ki PMID: 18501600
PMID: 18579385
NPC73738 POLB 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC73738 THPO 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC73738 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC8704 MMP13 1 13170 IC50 PMID: 22658537