Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC100551 | CA14 | 1 | 49800 | Ki |
PMID: 18579385 |
| NPC100551 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | HPGD | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC100809 | TRPA1 | 1 | 41000 | EC50 |
PMID: 20356305 |
| NPC10286 | CYP2C9 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC110899 | CA5B | 1 | 35400 | Ki |
PMID: 20185318 |
| NPC117572 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC125732 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC125732 | CYP2C19 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC125732 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC125732 | HTR3A | 1 | 26000 | EC50 |
PMID: 18033297 |
| NPC138113 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13991 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC149184 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149436 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | USP2 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | MAPT | 2 |
Median: 24068.2 Range: 19952.6 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | KDM4E | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | PTPN7 | 1 | 15400 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC163556 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC163556 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC163984 | ALDH1A1 | 2 |
Median: 25285.5 Range: 22387.2 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC173295 | POLB | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC173295 | ATM | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC173295 | KDM4E | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18205 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC201547 | ABCB1 | 1 | 31000 | IC50 |
PMID: 21354800 |
| NPC201844 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC201844 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC201844 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209296 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209296 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC213 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC217226 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC2476 | ALDH1A1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC255042 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC26960 | PTPN1 | 1 | 32600 | IC50 |
PMID: 25497963 |
| NPC270796 | CYP19A1 | 1 | 33200 | IC50 |
PMID: 16643058 |
| NPC270796 | ALDH1A1 | 2 |
Median: 22387.2 Range: 22387.2 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279026 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279026 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC279026 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC279026 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC290566 | TSHR | 3 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
| NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
| NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC300326 | PTGS1 | 1 | 39200 | IC50 |
PMID: 22386242 |
| NPC300326 | PTGS2 | 1 | 28000 | IC50 |
PMID: 22386242 |
| NPC301585 | PPARD | 1 | 24000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC301585 | PPARG | 1 | 21000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC302950 | ATM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | CYP1A2 | 1 | 34647 | IC50 |
PMID: 20696580 |
| NPC302950 | GSK3B | 1 | 26900 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC302950 | TP53 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC305016 | CYP3A4 | 1 | 23200 | Ki |
PMID: 16248836 |
| NPC40818 | ABCB1 | 1 | 39000 | IC50 |
PMID: 21354800 |
| NPC40818 | ABCG2 | 2 |
Median: 18000 Range: 17000 to 19000 |
IC50 |
PMID: 21354800 PMID: 21354800 |
| NPC44328 | TDP1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC47946 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC47946 | ALOX15 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC68889 | ALOX15 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC7491 | CYP2C9 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77858 | CD38 | 1 | 48600 | IC50 |
PMID: 21641214 |
| NPC79056 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC79056 | CTDSP1 | 1 | 20733 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC79943 | ALOX12 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC85233 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | ALDH1A1 | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | MAPT | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | KDM4E | 3 |
Median: 25118.9 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | CA6 | 2 |
Median: 1165950 Range: 11900 to 2320000 |
Ki |
PMID: 18579385 PMID: 21669522 |
| NPC100551 | CA4 | 1 | 11100 | Ki |
PMID: 18579385 |
| NPC10286 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC110899 | CA4 | 1 | 10600 | Ki |
PMID: 20185318 |
| NPC125732 | L3MBTL1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC148216 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | BLM | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC158179 | SMN1;SMN2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC201844 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC2476 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC270796 | FFAR1 | 2 |
Median: 23850 Range: 11700 to 36000 |
EC50 |
PMID: 24900539 PMID: 27326330 |
| NPC270796 | MAPT | 3 |
Median: 15848.9 Range: 11220.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC302950 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | HSD17B10 | 2 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC40818 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC7491 | CYP2C19 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77858 | AMY1A;AMY1B;AMY1C | 1 | 10200 | IC50 |
PMID: 18507367 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |
| NPC85233 | ABCB1 | 1 | 11500 | IC50 |
PMID: 11743742 |
| NPC85233 | MAPK1 | 2 |
Median: 21421.5 Range: 11220.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |