Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC113733 | POLB | 2 |
Median: 51840 Range: 43400 to 60280 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC133792 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137096 | TSHR | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | ACP1 | 4 |
Median: 22050 Range: 21200 to 22900 |
IC50 |
PMID: 21453996 PMID: 21453996 PMID: 25264584 PMID: 25264584 |
| NPC142415 | PTPN6 | 2 |
Median: 22760 Range: 14190 to 31330 |
IC50 |
PMID: 18707891 PMID: 27123900 |
| NPC154245 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC154245 | F3 | 2 |
Median: 52500 Range: 30000 to 75000 |
IC50 |
PMID: 9834151 PMID: 9834151 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178383 | TOP2A | 1 | 38600 | IC50 |
PMID: 11754608 |
| NPC181465 | XDH | 1 | 14800 | IC50 |
PMID: 9461655 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC264317 | POLB | 2 |
Median: 44925 Range: 43600 to 46250 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC264317 | GLI1 | 2 |
Median: 32000 Range: 32000 to 32000 |
IC50 |
PMID: 18842418 PMID: 19309080 |
| NPC281131 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | MAPT | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | EPHX2 | 1 | 21760 | IC50 |
PMID: 24679441 |
| NPC287231 | LMNA | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC40394 | PTPN1 | 1 | 15600 | IC50 |
PMID: 18798681 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC85661 | ALDH1A1 | 2 |
Median: 42239.55 Range: 39810.7 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
| NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
| NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | PTPRF | 2 |
Median: 17055 Range: 11800 to 22310 |
IC50 |
PMID: 21453996 PMID: 27123900 |
| NPC142415 | PTPN11 | 1 | 11620 | IC50 |
PMID: 27123900 |
| NPC238023 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC264317 | AKR1B1 | 1 | 11000 | IC50 |
PMID: 21561086 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
| NPC85661 | MAPT | 3 |
Median: 14125.4 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
| NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |