CMAUP Plant Collective Molecular Activities

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Human Protein Targets

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways

Pathway ID	Pathway Name	p-Value	Adjusted p-Value	Enriched Genes

Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases

ICD10 Disease Category	Disease Name	ICD10 Code	Linked Targets
G00-G99: Diseases of the nervous system G00-G99	Alzheimer disease	G30	MAOB
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Anxiety disorder	F32, F40-F42	MAOB
E00-E89: Endocrine, nutritional and metabolic diseases	Autoimmune diabetes	E08-E13	TLR2
A00-B99: Certain infectious and parasitic diseases	Bacterial infections	A00-B99	MAOB
C00-D49: Neoplasms	Myelodysplastic syndrome	D46	TLR2
E00-E89: Endocrine, nutritional and metabolic diseases	Obesity	E66	MAOB
S00-T88: Injury, poisoning and certain other consequences of external causes	Radiation sickness	T66	TLR2
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Cognitive disorders	F01-F07, F04, F05, R41.3	MAOB
G00-G99: Diseases of the nervous system G00-G99	Neurodegenerative disease	G30-G32	MAOB
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Major depressive episode without melancholia	F30-F39	MAOB
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Dementia	F01-F07	MAOB
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Depression	F30-F39	MAOB
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Idiopathic parkinson's disease	F02.3, G20	MAOB
I00-I99: Diseases of the circulatory system	Moderate to severe hypertension	I10-I16	MAOB
NA: NA	Motor symptoms	NA	MAOB
C00-D49: Neoplasms	Pancreatic cancer	C25	TLR2
G00-G99: Diseases of the nervous system G00-G99	Parkinson's disease	G20	MAOB; MAOB
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Major depressive disorder	F32, F33, M32	MAOB
C00-D49: Neoplasms	Melanoma	C43	TLR2
G00-G99: Diseases of the nervous system G00-G99	Central nervous system disease	G00-G99	MAOB
C00-D49: Neoplasms	Cancer	C00-C96	TLR2
C00-D49: Neoplasms	Prostate cancer	C61	TLR2
C00-D49: Neoplasms	Solid tumours	C00-D48	TLR2

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases

Plant Name: Eria tomentosa

Collective Molecular Activities at 10μM Activity Cutoff

List of Human Proteins Collectively Targeted by the Plant

List of Human Cytochrome P450 Enzymes Affected by the Plant

Detailed Information of Human Protein Targets

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways

Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases