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Plant Name: Ligularia atroviolacea




Collective Molecular Activities at 10μM Activity Cutoff

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target
Target Class
Target Proteins


List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme
Cytochrome P450 Enzymes:

Detailed Information of Human Protein Targets

Protein Class Gene ID Protein Name Uniprot ID Target ChEMBL ID
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)


Detailed Information of Enriched Gene Ontolgy
GO Type GO Category Enriched GO Terms p-Value Adjusted p-Value Enriched Genes
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways
Pathway ID Pathway Name p-Value Adjusted p-Value Enriched Genes
Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases
ICD10 Disease Category Disease Name ICD10 Code Linked Targets
C00-D49: Neoplasms Ovarian cancer C56 ABCB1
NA: NA Dyslipidemia NA PPARD
E00-E89: Endocrine, nutritional and metabolic diseases Dyslipidaemias E78 PPARD; PPARD
A00-B99: Certain infectious and parasitic diseases Bacterial infections A00-B99 ABCB1
G00-G99: Diseases of the nervous system G00-G99 Central nervous system disease G00-G99 PPARD
C00-D49: Neoplasms Adrenocortical carcinoma C74.0 ABCB1
E00-E89: Endocrine, nutritional and metabolic diseases Metabolic disorders E70-E89 PPARD
C00-D49: Neoplasms Cancer C00-C96 ABCB1; TLR2
C00-D49: Neoplasms Melanoma C43 TLR2
C00-D49: Neoplasms Solid tumours C00-D48 ABCB1; TLR2
E00-E89: Endocrine, nutritional and metabolic diseases Type 1 diabetes E10 PPARD
E00-E89: Endocrine, nutritional and metabolic diseases Type 2 diabetes E11 PPARD
C00-D49: Neoplasms Prostate cancer C61 TLR2
C00-D49: Neoplasms Myelodysplastic syndrome D46 TLR2
E00-E89: Endocrine, nutritional and metabolic diseases Obesity E66 PPARD; PPARD
C00-D49: Neoplasms Non-small cell lung cancer C33-C34 ABCB1
K00-K95: Diseases of the digestive system Non-alcoholic fatty liver disease K76.0 PPARD
S00-T88: Injury, poisoning and certain other consequences of external causes Radiation sickness T66 TLR2
E00-E89: Endocrine, nutritional and metabolic diseases Hyperlipidaemia E78 PPARD
I00-I99: Diseases of the circulatory system Atherosclerosis I70 PPARD
E00-E89: Endocrine, nutritional and metabolic diseases Autoimmune diabetes E08-E13 TLR2
C00-D49: Neoplasms Pancreatic cancer C25 TLR2
Data Section
Select to Download
1. General Info & Plant Usage & Geographical Distribution  
2. Human Target Proteins  
3. Target Gene Ontology  
4. Target KEGG Pathway  
5. Related Human Diseases  
About Us

The CMAUP database is developed by the Bioinformatics & Drug Design group (BIDD), which is based in the Department of Pharmacy, National University of Singapore, Singapore.

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Singapore, 117549, National University of Singapore

Principle Investigator:
Prof. Chen Yu Zong
phacyz@nus.edu.sg

Developer & Maintainer:
Dr. Zeng Xian
zengxian@u.edu.nus

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