CMAUP Plant Collective Molecular Activities

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Human Protein Targets

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways

Pathway ID	Pathway Name	p-Value	Adjusted p-Value	Enriched Genes

Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases

ICD10 Disease Category	Disease Name	ICD10 Code	Linked Targets
C00-D49: Neoplasms	Solid tumours	C00-D48	TOP1
I00-I99: Diseases of the circulatory system	Thromboembolism	I80-I82	F10
I00-I99: Diseases of the circulatory system	Thrombosis	I80-I82	F10
I00-I99: Diseases of the circulatory system	Thromboembolic disorders	I80-I82	F10
I00-I99: Diseases of the circulatory system	Deep venous clots	I80.2	F10
I00-I99: Diseases of the circulatory system	Venous thromboembolism	I80-I82	F10
I00-I99: Diseases of the circulatory system	Venous thrombosis	I80-I82	F10
C00-D49: Neoplasms	Metastatic colorectal cancer	C18-C21	TOP1
C00-D49: Neoplasms	Esophageal cancer	C15	TOP1
NA: NA	Haemophilia B	NA	F10
C00-D49: Neoplasms	Bladder cancer	C67	TOP1
I00-I99: Diseases of the circulatory system	Bleeding	I74, I80-I82	F10
D50-D89: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	Blood coagulation disorders	D65-D68	F10
C00-D49: Neoplasms	Advanced ovarian cancer	NA	TOP1
C00-D49: Neoplasms	Breast cancer	C50	TOP1
C00-D49: Neoplasms	Metastatic breast cancer	C50	TOP1; TOP1
C00-D49: Neoplasms	Cancer	C00-C96	TOP1
C00-D49: Neoplasms	Glioblastoma multiforme	C71	TOP1
A00-B99: Certain infectious and parasitic diseases	Human immunodeficiency virus infection	B20-B26	TOP1
I00-I99: Diseases of the circulatory system	Cerebrovascular ischaemia	I61-I63	F10
C00-D49: Neoplasms	Lung cancer	C33-C34	TOP1
I00-I99: Diseases of the circulatory system	Angina pectoris	I20	F10
NA: NA	Christmas disease	NA	F10
C00-D49: Neoplasms	Late-stage solid tumors	C00-C75, C7A, C7B, D10-D36, D3A	TOP1
D50-D89: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	Hematology	D50-D77	F10
D50-D89: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	Hemophilia	D66-D68	F10
I00-I99: Diseases of the circulatory system	Deep vein thrombosis	I80-I82, I80.2	F10
I00-I99: Diseases of the circulatory system	Acute coronary syndrome	I74	F10
A00-B99: Certain infectious and parasitic diseases	Acquired immune deficiency syndrome	B20	TOP1
I00-I99: Diseases of the circulatory system	Coagulation	I80-I82	F10
C00-D49: Neoplasms	Gastric cancer	C16	TOP1
C00-D49: Neoplasms	Myelodysplastic syndrome	D46	TOP1
I00-I99: Diseases of the circulatory system	Prophylaxis of deep vein thrombosis	I80-I82, I80.2	F10
C00-D49: Neoplasms	Renal cancer	C64	F10
C00-D49: Neoplasms	Ovarian cancer	C56	TOP1
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Attention deficit hyperactivity disorder	F90	F10
E00-E89: Endocrine, nutritional and metabolic diseases	Atrial fibrillation	E78, I48	F10
C00-D49: Neoplasms	Colorectal cancer	C18-C21	TOP1

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases

Plant Name: Plantago indica

Collective Molecular Activities at 10μM Activity Cutoff

List of Human Proteins Collectively Targeted by the Plant

List of Human Cytochrome P450 Enzymes Affected by the Plant

Detailed Information of Human Protein Targets

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways

Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases