CMAUP Plant Collective Molecular Activities

Plant Name: Amomum compactum

Collective Molecular Activities at 10μM Activity Cutoff

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Human Protein Targets

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways

Pathway ID	Pathway Name	p-Value	Adjusted p-Value	Enriched Genes

Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases

ICD10 Disease Category	Disease Name	ICD10 Code	Linked Targets
E00-E89: Endocrine, nutritional and metabolic diseases	Hypothyroidism	E03	THRB
E00-E89: Endocrine, nutritional and metabolic diseases	Lipid metabolism disorder	E75-E78	THRB
G00-G99: Diseases of the nervous system G00-G99	Alzheimer disease	G30	MAPT
W85-W99: Exposure to electric current, radiation and extreme ambient air temperature and pressure	Diagnostic test to differentiate primary and secondary hypothyroidism	W88	TSHR
F01-F99: Mental, Behavioral and Neurodevelopmental disorders	Cognitive disorders	F01-F07, F04, F05, R41.3	MAPT
E00-E89: Endocrine, nutritional and metabolic diseases	High cholesterol levels in blood	E78.0	THRB
E00-E89: Endocrine, nutritional and metabolic diseases	Hyperthyroidism	E05	THRB
I00-I99: Diseases of the circulatory system	Restenosis	I51.89	MAPK1
G00-G99: Diseases of the nervous system G00-G99	Central nervous system disease	G00-G99	MAPT
C00-D49: Neoplasms	Thyroid cancer diagnosis	C73	TSHR
C00-D49: Neoplasms	Solid tumours	C00-D48	MAPK1
G00-G99: Diseases of the nervous system G00-G99	Pain	G64, G90.0, R52, G89	TRPA1
S00-T88: Injury, poisoning and certain other consequences of external causes	Wound healing	T14.0-T14.1	THRB
E00-E89: Endocrine, nutritional and metabolic diseases	Hyperlipidaemia	E78	THRB
G00-G99: Diseases of the nervous system G00-G99	Neurodegenerative disease	G30-G32	MAPT
C00-D49: Neoplasms	Thyroid cancer	C73	TSHR
J00-J99: Diseases of the respiratory system	Throat irritation	J39.2	TRPA1
C00-D49: Neoplasms	Cancer	C00-C96	MAPK1

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases