Cytochrome P450 Enzymes: |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
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GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
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Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|
hsa04727 | GABAergic synapse_Homo sapiens_hsa04727 | 1.128E-07 | 2.594E-06 | GABBR1; GABRR1; SLC6A11; SLC6A1 |
hsa02010 | ABC transporters_Homo sapiens_hsa02010 | 2.569E-04 | 2.954E-03 | ABCB1; ABCG2 |
hsa04976 | Bile secretion_Homo sapiens_hsa04976 | 6.694E-04 | 5.132E-03 | ABCB1; ABCG2 |
hsa05032 | Morphine addiction_Homo sapiens_hsa05032 | 1.097E-03 | 6.305E-03 | GABBR1; GABRR1 |
hsa04080 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 9.680E-03 | 4.453E-02 | GABBR1; GABRR1 |
ICD10 Disease Category | Disease Name | ICD10 Code | Linked Targets |
---|---|---|---|
A00-B99: Certain infectious and parasitic diseases | Bacterial infections | A00-B99 | ABCB1 |
R00-R99: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified | Convulsions | R56.0 | SLC6A1 |
C00-D49: Neoplasms | Myeloma | C90 | SLC6A1 |
C00-D49: Neoplasms | Adrenocortical carcinoma | C74.0 | ABCB1 |
C00-D49: Neoplasms | Advanced breast cancer | C50 | CYP19A1 |
C00-D49: Neoplasms | Ovarian cancer | C56 | ABCB1 |
C00-D49: Neoplasms | Hormonally-responsive breast cancer | C50 | CYP19A1 |
N00-N99: Diseases of the genitourinary system | Prostate disease | N42.9 | CYP19A1 |
C00-D49: Neoplasms | Non-small cell lung cancer | C33-C34 | ABCB1 |
C00-D49: Neoplasms | Bladder cancer | C67 | CYP19A1 |
C00-D49: Neoplasms | Breast cancer | C50 | CYP19A1 |
C00-D49: Neoplasms | Cancer | C00-C96 | ABCB1 |
C00-D49: Neoplasms | Solid tumours | C00-D48 | ABCB1 |
N00-N99: Diseases of the genitourinary system | Endometriosis | N80 | CYP19A1 |