| ICD10 Disease Category |
Disease Name |
ICD10 Code |
Linked Targets |
| G00-G99: Diseases of the nervous system G00-G99 |
Pain |
G64, G90.0, R52, G89 |
HTR2C; OPRD1 |
| E00-E89: Endocrine, nutritional and metabolic diseases |
Obesity |
E66 |
PTPN1; HTR2C; HTR2C |
| C00-D49: Neoplasms |
Aggressive non-hodgkin's lymphoma |
C81, C81-C86, C82-C85, C91-C95 |
HTR2C |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Alcohol use disorders |
F10.2 |
HTR2C; OPRD1 |
| A00-B99: Certain infectious and parasitic diseases |
Infections |
A00-B99 |
PTPN1 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Mood disorder |
F30-F39 |
HTR2C |
| C00-D49: Neoplasms |
Multiple myeloma |
C90 |
VCP |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Anxiety disorder |
F32, F40-F42 |
HTR2C; OPRD1 |
| K00-K95: Diseases of the digestive system |
Gastric motility disorder |
K22.4 |
DRD3 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Female sexual dysfunction |
F52 |
DRD3 |
| C00-D49: Neoplasms |
Overactive bladder disorder |
C67, N32.81 |
OPRD1 |
| C00-D49: Neoplasms |
Cancer |
C00-C96 |
MCL1 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Male sexual disorders |
F52 |
DRD3 |
| K00-K95: Diseases of the digestive system |
Diarrhea-predominant IBS |
K58.0 |
OPRD1 |
| NA: NA |
Chronic diarrhea associated with inflammatory bowel disease |
NA |
OPRD1 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Generalized anxiety disorder |
F32, F40-F42, F41.1 |
HTR2C |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Major depressive disorder |
F32, F33, M32 |
HTR2C; HTR2C; OPRD1 |
| E00-E89: Endocrine, nutritional and metabolic diseases |
Diabetes |
E23.2, N25.1 |
PTPN1; HTR2C |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Cocaine addiction |
F14.2 |
DRD3 |
| I00-I99: Diseases of the circulatory system |
Neurological disease |
I21, I22, R52, R52.1-R52.2, R60.9, G89 |
HTR2C |
| I00-I99: Diseases of the circulatory system |
Ischemic heart diseases |
I20-I25 |
OPRD1 |
| E00-E89: Endocrine, nutritional and metabolic diseases |
Metabolic disorders |
E70-E89 |
HTR2C |
| R00-R99: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified |
Cough |
R05 |
OPRD1 |
| N00-N99: Diseases of the genitourinary system |
Bladder disease |
N30-N32 |
OPRD1 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Depression |
F30-F39 |
HTR2C |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Drug abuse |
F10-F19 |
HTR2C; DRD3 |
| M00-M99: Diseases of the musculoskeletal system and connective tissue |
Rheumatoid arthritis |
M05-M06 |
OPRD1 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Schizophrenia |
F20 |
HTR2C; DRD3 |
| R00-R99: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified |
Emesis |
R11 |
DRD3 |
| NA: NA |
Sleep initiation and maintenance disorders |
NA |
HTR2C |
| R00-R99: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified |
Moderate-to-severe pain |
R52, G89 |
OPRD1 |
| N00-N99: Diseases of the genitourinary system |
Urinary incontinence |
N39.3, N39.4, R32 |
OPRD1 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Premature ejaculation |
F52.4 |
OPRD1 |
| E00-E89: Endocrine, nutritional and metabolic diseases |
Type 2 diabetes |
E11 |
PTPN1; PTPN1 |
| G00-G99: Diseases of the nervous system G00-G99 |
Migraine headaches |
G43 |
HTR2C |
| NA: NA |
Primary insomnia |
NA |
HTR2C |
| NA: NA |
Acute nonspecific diarrhea |
NA |
OPRD1 |
| G00-G99: Diseases of the nervous system G00-G99 |
Acute migraine |
G43 |
OPRD1 |
| NA: NA |
Colour dead tissues |
NA |
PTPN1 |
| F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Psychotic disorders |
F20-F29 |
HTR2C; DRD3 |
