CMAUP Plant Collective Molecular Activities

Plant Name: Corymbia scabrida

Collective Molecular Activities at 10μM Activity Cutoff

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Human Protein Targets

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways

Pathway ID	Pathway Name	p-Value	Adjusted p-Value	Enriched Genes

Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases

ICD10 Disease Category	Disease Name	ICD10 Code	Linked Targets
L00-L99: Diseases of the skin and subcutaneous tissue	Pruritus	L29	ALOX5
L00-L99: Diseases of the skin and subcutaneous tissue	Psoriasis	L40	ALOX5
J00-J99: Diseases of the respiratory system	Respiratory disease	J00-J99	ALOX5
L00-L99: Diseases of the skin and subcutaneous tissue	Dermatitis	L20-L30	ALOX5
C00-D49: Neoplasms	Inflammatory disease	C11, C44, K75.9, M00-M25	ALOX5
L00-L99: Diseases of the skin and subcutaneous tissue	Atopic dermatitis	L00-L99	ALOX5
J00-J99: Diseases of the respiratory system	Chronic obstructive pulmonary disease	J40-J44, J47	ALOX5
J00-J99: Diseases of the respiratory system	Asthma	J45	ALOX5; ALOX5
A00-B99: Certain infectious and parasitic diseases	Lymphatic filariasis	B74	ALOX5
I00-I99: Diseases of the circulatory system	Atherosclerosis	I70	ALOX5
S00-T88: Injury, poisoning and certain other consequences of external causes	Allergy	T78.4	ALOX5
G00-G99: Diseases of the nervous system G00-G99	Alzheimer disease	G30	PTGES
M00-M99: Diseases of the musculoskeletal system and connective tissue	Osteoarthritis	M15-M19, M47	ALOX5
E00-E89: Endocrine, nutritional and metabolic diseases	Inflammation	E08-E13, E10.2, E11, E11.2, E13.2, I73.9, I80-I82, N00-N29, G89	ALOX5
I00-I99: Diseases of the circulatory system	Thrombosis	I80-I82	ALOX5
M00-M99: Diseases of the musculoskeletal system and connective tissue	Rheumatoid arthritis	M05-M06	ALOX5
J00-J99: Diseases of the respiratory system	Rhinitis	J00, J30, J31.0	ALOX5
A00-B99: Certain infectious and parasitic diseases	Fungal infections	B35-B49	ALOX5
M00-M99: Diseases of the musculoskeletal system and connective tissue	Arthritis	M00-M25	ALOX5

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases