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Plant Name: Cirsium chinense




Collective Molecular Activities at 10μM Activity Cutoff

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target
Target Class
Target Proteins


List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme
Cytochrome P450 Enzymes:

Detailed Information of Human Protein Targets

Protein Class Gene ID Protein Name Uniprot ID Target ChEMBL ID
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)


Detailed Information of Enriched Gene Ontolgy
GO Type GO Category Enriched GO Terms p-Value Adjusted p-Value Enriched Genes
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways
Pathway ID Pathway Name p-Value Adjusted p-Value Enriched Genes
Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases
ICD10 Disease Category Disease Name ICD10 Code Linked Targets
G00-G99: Diseases of the nervous system G00-G99 Diagnostic imaging G30, I73.9 APP
C00-D49: Neoplasms Glioma C71 APP
H00-H59: Diseases of the eye and adnexa Glaucoma H40-H42 ADORA3
NA: NA Geographic retinal atrophy NA APP
E00-E89: Endocrine, nutritional and metabolic diseases Amyloidosis E85 APP
I00-I99: Diseases of the circulatory system Neurological disease I21, I22, R52, R52.1-R52.2, R60.9, G89 APP
I00-I99: Diseases of the circulatory system Ischemia I99.8 ADORA3
NA: NA Hepatitis C virus infection NA ADORA3
C00-D49: Neoplasms Hepatocellular carcinoma C22.0 ADORA3
E00-E89: Endocrine, nutritional and metabolic diseases Inflammation E08-E13, E10.2, E11, E11.2, E13.2, I73.9, I80-I82, N00-N29, G89 ADORA3
H00-H59: Diseases of the eye and adnexa Macular degeneration H35.3 APP
A00-B99: Certain infectious and parasitic diseases Malaria B54 ADORA3
F01-F99: Mental, Behavioral and Neurodevelopmental disorders Mild cognitive impairment F06.7 APP
G00-G99: Diseases of the nervous system G00-G99 Mild to moderate alzheimer disease G30 APP
I00-I99: Diseases of the circulatory system Cerebrovascular ischaemia I61-I63 ADORA3
I00-I99: Diseases of the circulatory system Cerebral amyloid angiopathy I68.0 APP
H00-H59: Diseases of the eye and adnexa Age related macular degeneration H35.3 APP
C00-D49: Neoplasms Cancer C00-C96 ADORA3; APP
G00-G99: Diseases of the nervous system G00-G99 Alzheimer disease G30 APP
S00-T88: Injury, poisoning and certain other consequences of external causes Brain injury S09.90 APP
Data Section
Select to Download
1. General Info & Plant Usage & Geographical Distribution  
2. Human Target Proteins  
3. Target Gene Ontology  
4. Target KEGG Pathway  
5. Related Human Diseases  
About Us

The CMAUP database is developed by the Bioinformatics & Drug Design group (BIDD), which is based in the Department of Pharmacy, National University of Singapore, Singapore.

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Singapore, 117549, National University of Singapore

Principle Investigator:
Prof. Chen Yu Zong
phacyz@nus.edu.sg

Developer & Maintainer:
Dr. Zeng Xian
zengxian@u.edu.nus

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