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Plant Name: Callicarpa macrophylla




Collective Molecular Activities at 10μM Activity Cutoff

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target
Target Class
Target Proteins


List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme
Cytochrome P450 Enzymes:

Detailed Information of Human Protein Targets

Protein Class Gene ID Protein Name Uniprot ID Target ChEMBL ID
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)


Detailed Information of Enriched Gene Ontolgy
GO Type GO Category Enriched GO Terms p-Value Adjusted p-Value Enriched Genes
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10, ordered by adjusted p-value

Detailed Information of Enriched KEGG Pathways
Pathway ID Pathway Name p-Value Adjusted p-Value Enriched Genes
Human Diseases Associated with the Target Proteins of the Plant (Activity≤10μM)

Detailed Information of Human Diseases
ICD10 Disease Category Disease Name ICD10 Code Linked Targets
E00-E89: Endocrine, nutritional and metabolic diseases Hyperlipidaemia E78 HCAR2
C00-D49: Neoplasms Lung cancer C33-C34 MMP2
C00-D49: Neoplasms Renal cell carcinoma NA MMP2
I00-I99: Diseases of the circulatory system Aortic aneurysm I71 MMP12
I00-I99: Diseases of the circulatory system Acute ischemic stroke I61-I63 HCAR2
C00-D49: Neoplasms Solid tumours C00-D48 MMP2
J00-J99: Diseases of the respiratory system Chronic obstructive pulmonary disease J40-J44, J47 MMP12; MMP12
I00-I99: Diseases of the circulatory system Cardiovascular disorder I00-I99 HCAR2
F01-F99: Mental, Behavioral and Neurodevelopmental disorders Major depressive disorder F32, F33, M32 HCAR2
C00-D49: Neoplasms Inflammatory disease C11, C44, K75.9, M00-M25 MMP12
I00-I99: Diseases of the circulatory system Atherosclerosis I70 MMP12; HCAR2
J00-J99: Diseases of the respiratory system Asthma J45 MMP12
I00-I99: Diseases of the circulatory system Arteriosclerosis I70 HCAR2
C00-D49: Neoplasms Non-small-cell lung cancer NA MMP2
L00-L99: Diseases of the skin and subcutaneous tissue Acne vulgaris L70.0 MMP2
E00-E89: Endocrine, nutritional and metabolic diseases Metabolic disorders E70-E89 GPBAR1
M00-M99: Diseases of the musculoskeletal system and connective tissue Osteoarthritis M15-M19, M47 MMP2
C00-D49: Neoplasms Pancreatic cancer C25 MMP2
C00-D49: Neoplasms Ovarian cancer C56 MMP2
C00-D49: Neoplasms Cancer C00-C96 MMP2
E00-E89: Endocrine, nutritional and metabolic diseases Type 2 diabetes E11 GPBAR1; HCAR2
Data Section
Select to Download
1. General Info & Plant Usage & Geographical Distribution  
2. Human Target Proteins  
3. Target Gene Ontology  
4. Target KEGG Pathway  
5. Related Human Diseases  
About Us

The CMAUP database is developed by the Bioinformatics & Drug Design group (BIDD), which is based in the Department of Pharmacy, National University of Singapore, Singapore.

CMAUP

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Singapore, 117549, National University of Singapore

Principle Investigator:
Prof. Chen Yu Zong
phacyz@nus.edu.sg

Developer & Maintainer:
Dr. Zeng Xian
zengxian@u.edu.nus

© 2018 Copyright: Bioinformatics & Drug Design group