TCM-ID Component

Component: Cucumis melo 瓜蒂

Description of the Component

Component ID	TCMH704
Latin Name	Cucumis melo
English Name	Muskmelon fruit pedicel
Chinese Pinyin Name	Gua Di
中文名	瓜蒂
TCM Properties	Cold,Bitter
TCM Meridians	Stomach
Therapeutic Class English	Vomiting promotion
Therapeutic Class Chinese	涌吐
Functions	Vomiting promotion
Toxicity	Extremely Toxic
Geo-authentic habitats (道地产区)	NA
Reference	SATCM
Barcode ID	ITSAL2157-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx1890	Madness Suppressant Recipe	挽狂汤
TCMFx1543	Pedicellus Melo Powder	瓜蒂散
TCMFx1549	Three Saint Stroke Powder	三圣散

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC958
Formula: C32H46O8

Common Name	Cucurbitacin B
IUPAC Name	[(E,6R)-6-[(2S,8S,9R,10S,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
Canonical SMILES	CC(=O)OC(/C=C/C(=O)[C@@]([C@H]1[C@H](O)C[C@@]2([C@]1(C)CC(=O)[C@@]1([C@H]2CC=C2[C@@H]1C[C@H](O)C(=O)C2(C)C)C)C)(O)C)(C)C
Standard InCHI	InChI=1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20-,21+,22-,25-,29-,30+,31-,32-/m0/s1
Standard InCHIKey	IXQKXEUSCPEQRD-QATBOUOLSA-N
External Identifiers	ChEMBL [CHEMBL507237]; PubChem [15944763];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2085	Cucumis melo	Tian Gua Zi	甜瓜子
TCMH704	Cucumis melo	Gua Di	瓜蒂

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC958	C32H46O8	Cucurbitacin B	558.32	0.7709	4.1	2.725	8	3	138.2	18	4	40	0

Download Data

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)