TCM-ID Component

Component: Cucumis melo 甜瓜子

Description of the Component

Component ID	TCMH2085
Latin Name	Cucumis melo
English Name	muskmelon seed
Chinese Pinyin Name	Tian Gua Zi
中文名	甜瓜子
TCM Properties	Cold,Bitter
TCM Meridians	Liver,Heart
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAL2157-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx3386	Die Da Tablets	跌打片
TCMFx3449	Die Da Zhi Tong Powder	跌打止痛散
TCMF4387	Huo Xue Li Shang Pills	活血理伤丸
TCMFx4640	Jie Gu Pills	接骨丸
TCMFx5646	Shang Ke Ba Li Powder	伤科八厘散
TCMFx507	Shang Ke Jie Gu Tablet	伤科接骨片
TCMFx5677	Shang Ke Jie Gu Tablets	伤科接骨片
TCMFx6092	Zhi Shang Die Da Pills	治伤跌打丸

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC958
Formula: C32H46O8

Common Name	Cucurbitacin B
IUPAC Name	[(E,6R)-6-[(2S,8S,9R,10S,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
Canonical SMILES	CC(=O)OC(/C=C/C(=O)[C@@]([C@H]1[C@H](O)C[C@@]2([C@]1(C)CC(=O)[C@@]1([C@H]2CC=C2[C@@H]1C[C@H](O)C(=O)C2(C)C)C)C)(O)C)(C)C
Standard InCHI	InChI=1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20-,21+,22-,25-,29-,30+,31-,32-/m0/s1
Standard InCHIKey	IXQKXEUSCPEQRD-QATBOUOLSA-N
External Identifiers	ChEMBL [CHEMBL507237]; PubChem [15944763];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2085	Cucumis melo	Tian Gua Zi	甜瓜子
TCMH704	Cucumis melo	Gua Di	瓜蒂

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC958	C32H46O8	Cucurbitacin B	558.32	0.7709	4.1	2.725	8	3	138.2	18	4	40	0

Download Data

All data can be downloaded by:

→ Selecting data type in the below download table
→ Then click the download button.

Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)