NPASS Compound

Structure

CID143168 OpenBabel06191715502D 21 21 0 0 0 0 0 0 0 0999 V2000 -8.6603 -0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.6603 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.7942 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.9282 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0622 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.1962 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3301 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4641 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5981 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7321 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7321 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7321 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8660 0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8660 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 -0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5981 -1.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8660 1.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8660 -2.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 0.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 2 3 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 8 9 1 0 0 0 0 9 10 1 0 0 0 0 10 11 1 0 0 0 0 11 13 1 0 0 0 0 12 14 2 0 0 0 0 12 15 1 0 0 0 0 13 16 1 0 0 0 0 13 17 2 0 0 0 0 14 16 1 0 0 0 0 14 18 1 0 0 0 0 15 17 1 0 0 0 0 15 19 2 0 0 0 0 16 20 2 0 0 0 0 17 21 1 0 0 0 0 M END $$$$

Physi-Chem Properties

Molecular Weight:	294.18
Volume:	318.647
LogP:	4.935
LogD:	3.371
LogS:	-3.397
# Rotatable Bonds:	9
TPSA:	80.92
# H-Bond Aceptor:	4
# H-Bond Donor:	4
# Rings:	1
# Heavy Atoms:	4

MedChem Properties

QED Drug-Likeness Score:	0.236
Synthetic Accessibility Score:	2.631
Fsp3:	0.529
Lipinski Rule-of-5:	Accepted
Pfizer Rule:	Accepted
GSK Rule:	Rejected
BMS Rule:	0
Golden Triangle Rule:	Accepted
Chelating Alert:	1
PAINS Alert:	1

ADMET Properties (ADMETlab2.0)

ADMET: Absorption

Caco-2 Permeability:	-4.905
MDCK Permeability:	2.5223613192792982e-05
Pgp-inhibitor:	0.002
Pgp-substrate:	0.003
Human Intestinal Absorption (HIA):	0.006
20% Bioavailability (F20%):	0.994
30% Bioavailability (F30%):	0.999

ADMET: Distribution

Blood-Brain-Barrier Penetration (BBB):	0.023
Plasma Protein Binding (PPB):	98.78385162353516%
Volume Distribution (VD):	3.419
Pgp-substrate:	1.5573070049285889%

ADMET: Metabolism

CYP1A2-inhibitor:	0.799
CYP1A2-substrate:	0.27
CYP2C19-inhibitor:	0.334
CYP2C19-substrate:	0.061
CYP2C9-inhibitor:	0.457
CYP2C9-substrate:	0.785
CYP2D6-inhibitor:	0.794
CYP2D6-substrate:	0.375
CYP3A4-inhibitor:	0.128
CYP3A4-substrate:	0.049

ADMET: Excretion

Clearance (CL):	10.018
Half-life (T1/2):	0.878

ADMET: Toxicity

hERG Blockers:	0.013
Human Hepatotoxicity (H-HT):	0.013
Drug-inuced Liver Injury (DILI):	0.009
AMES Toxicity:	0.545
Rat Oral Acute Toxicity:	0.083
Maximum Recommended Daily Dose:	0.032
Skin Sensitization:	0.971
Carcinogencity:	0.247
Eye Corrosion:	0.24
Eye Irritation:	0.938
Respiratory Toxicity:	0.22

Download Data

Data Type	Select
General Info & Identifiers & Properties
Structure MOL file
Source Organisms
Biological Activities
Similar NPs/Drugs

Natural Product: NPC143168

Natural Product ID:	NPC143168
*Common Name:**	Embelin
IUPAC Name:	2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
Synonyms:	Embelin
Standard InCHIKey:	IRSFLDGTOHBADP-UHFFFAOYSA-N
Standard InCHI:	InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3
SMILES:	CCCCCCCCCCCC1=C(O)C(=O)C=C(C1=O)O
Synthetic Gene Cluster:	n.a.
ChEMBL Identifier:	CHEMBL221137
PubChem CID:	3218
Chemical Classification:**	CHEMONTID:0000000 [Organic compounds] [CHEMONTID:0004603] Organic oxygen compounds [CHEMONTID:0000323] Organooxygen compounds [CHEMONTID:0001831] Carbonyl compounds [CHEMONTID:0000118] Ketones [CHEMONTID:0003487] Cyclic ketones [CHEMONTID:0002495] Quinones [CHEMONTID:0002384] Benzoquinones [CHEMONTID:0002494] P-benzoquinones

*Note: the InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.
**Note: the Chemical Classification was calculated by NPClassifier Version 1.5. Reference: PMID:34662515.

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Isolation Part	Collection Location	Collection Time	Reference
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	twig	n.a.	DOI[10.1021/np50063a031]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	stem	n.a.	DOI[10.1021/np50063a031]
NPO31008	Ardisia colorata	Species	Primulaceae	Eukaryota	n.a.	fruit	n.a.	PMID[11767097]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[15165134]
NPO6583	Clematis chinensis	Species	Ranunculaceae	Eukaryota	roots	n.a.	n.a.	PMID[15387651]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	twig	n.a.	PMID[16254827]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	stem	n.a.	PMID[16254827]
NPO15741	Embelia ribes	Species	Primulaceae	Eukaryota	n.a.	leaf	n.a.	PMID[17124632]
NPO15741	Embelia ribes	Species	Primulaceae	Eukaryota	n.a.	fruit	n.a.	PMID[17124632]
NPO15741	Embelia ribes	Species	Primulaceae	Eukaryota	roots	n.a.	n.a.	PMID[17125236]
NPO15741	Embelia ribes	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[17125236]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	whole plant	n.a.	PMID[17243725]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	whole plants	Sendai, Miyagi Prefecture, Japan	2000-Sep	PMID[17243725]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	whole plant	n.a.	PMID[17397219]
NPO24009	Claviceps purpurea	Species	Clavicipitaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[17841110]
NPO31008	Ardisia colorata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[19124248]
NPO17039	Pharbitis nil	Species	Convolvulaceae	Eukaryota	Seeds	n.a.	n.a.	PMID[19435339]
NPO6583	Clematis chinensis	Species	Ranunculaceae	Eukaryota	roots and rhizomes	Shaoguan, Guangdong Province, China	2007-Dec	PMID[20540535]
NPO24009	Claviceps purpurea	Species	Clavicipitaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[20778930]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[22316191]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[22940450]
NPO31062	Pharbitis nil	n.a.	n.a.	n.a.	n.a.	n.a.	n.a.	PMID[23815260]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[2778454]
NPO23736	Myrsine africana	Species	Primulaceae	Eukaryota	root	n.a.	n.a.	PMID[2778455]
NPO23736	Myrsine africana	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29300477]
NPO23736	Myrsine africana	Species	Primulaceae	Eukaryota	n.a.	fruit	n.a.	Database[Article]
NPO6583	Clematis chinensis	Species	Ranunculaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO25404	Embelia kilimandscharica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO7829	Embelia robusta	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO8074	Myrsine semiserrata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO7334	Embelia barbeyana	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO31008	Ardisia colorata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO5107	Rapanea umbellata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO10011	Myrsine capitellata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO15741	Embelia ribes	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO6973	Connarus ritchiei	Species	Connaraceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO31062	Pharbitis nil	n.a.	n.a.	n.a.	n.a.	n.a.	n.a.	Database[HerDing]
NPO14801	Embelia oblongifolia	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO26639	Ardisia crenata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO12633	Rapanea neurophylla	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO11225	Embelia tsjersium-cottam	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO23736	Myrsine africana	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO31459	Rapanea sp	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO24009	Claviceps purpurea	Species	Clavicipitaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO2249	Ardisia humilis	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO23736	Myrsine africana	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO15536	Rapanea sp.	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO2249	Ardisia humilis	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO14801	Embelia oblongifolia	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO11225	Embelia tsjersium-cottam	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO8074	Myrsine semiserrata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO15741	Embelia ribes	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO24009	Claviceps purpurea	Species	Clavicipitaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO26639	Ardisia crenata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO10011	Myrsine capitellata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO6973	Connarus ritchiei	Species	Connaraceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO7334	Embelia barbeyana	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO12633	Rapanea neurophylla	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO17039	Pharbitis nil	Species	Convolvulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO6583	Clematis chinensis	Species	Ranunculaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO7829	Embelia robusta	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO25404	Embelia kilimandscharica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO8627	Ardisia paniculata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO5107	Rapanea umbellata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO24009	Claviceps purpurea	Species	Clavicipitaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO31062	Pharbitis nil	n.a.	n.a.	n.a.	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO6583	Clematis chinensis	Species	Ranunculaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO17039	Pharbitis nil	Species	Convolvulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TM-MC]
NPO6583	Clematis chinensis	Species	Ranunculaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TM-MC]
NPO26639	Ardisia crenata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TM-MC]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TM-MC]
NPO2249	Ardisia humilis	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO26639	Ardisia crenata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO17145	Aegiceras corniculatum	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO5107	Rapanea umbellata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO23736	Myrsine africana	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO12633	Rapanea neurophylla	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO8074	Myrsine semiserrata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO3803	Ardisia japonica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO6583	Clematis chinensis	Species	Ranunculaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO15741	Embelia ribes	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO7829	Embelia robusta	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO24009	Claviceps purpurea	Species	Clavicipitaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO10011	Myrsine capitellata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO17039	Pharbitis nil	Species	Convolvulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO25404	Embelia kilimandscharica	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO7334	Embelia barbeyana	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO8627	Ardisia paniculata	Species	Primulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]

☑ Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
☉ UNPD: Universal Natural Products Database [PMID: 23638153].
☉ StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
☉ TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
☉ TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
☉ TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
☉ TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
☉ HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
☉ MetaboLights: a metabolomics database [PMID: 27010336].
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

NP Quantity Composition/Concentration

Organism ID	NP ID	Organism Material Preparation	Organism Part	NP Quantity (Standard)	NP Quantity (Minimum)	NP Quantity (Maximum)	Quantity Unit	Reference

☑ Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
☉ DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
☉ PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

Biological Activity

Activity Type	# Activity
AC50	1
EC50	14
GI50	58
IC50	691
Ki	2
MIC	7
Others	38
Potency	74

Activity Type	# Activity
Cell Line	745
Individual Protein	83
NON-MOLECULAR	2
Organism	19
Others	15
Protein-Protein Interaction	7
SINGLE PROTEIN	15

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT4309	Individual Protein	Inhibitor of apoptosis protein 3	Homo sapiens	IC50	=	4100.0	nM	PMID[488354]
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	3700.0	nM	PMID[488354]
NPT858	Cell Line	LNCaP	Homo sapiens	IC50	=	5700.0	nM	PMID[488354]
NPT4642	Cell Line	PrEC	Homo sapiens	IC50	=	20100.0	nM	PMID[488354]
NPT1374	Cell Line	WI-38	Homo sapiens	IC50	=	19300.0	nM	PMID[488354]
NPT306	Cell Line	PC-3	Homo sapiens	Apoptosis	=	30.0	%	PMID[488354]
NPT306	Cell Line	PC-3	Homo sapiens	Apoptosis	=	75.0	%	PMID[488354]
NPT306	Cell Line	PC-3	Homo sapiens	Staining	=	33.0	%	PMID[488354]
NPT306	Cell Line	PC-3	Homo sapiens	Staining	=	62.1	%	PMID[488354]
NPT15	Cell Line	Jurkat	Homo sapiens	IC50	=	20000.0	nM	PMID[488354]
NPT4309	Individual Protein	Inhibitor of apoptosis protein 3	Homo sapiens	IC50	=	4100.0	nM	PMID[488355]
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	3700.0	nM	PMID[488355]
NPT858	Cell Line	LNCaP	Homo sapiens	IC50	=	5700.0	nM	PMID[488355]
NPT4642	Cell Line	PrEC	Homo sapiens	IC50	=	20100.0	nM	PMID[488355]
NPT4643	Cell Line	WI-38 5000	Homo sapiens	IC50	=	19300.0	nM	PMID[488355]
NPT306	Cell Line	PC-3	Homo sapiens	Induction	=	30.0	%	PMID[488355]
NPT306	Cell Line	PC-3	Homo sapiens	Induction	=	75.0	%	PMID[488355]
NPT306	Cell Line	PC-3	Homo sapiens	Induction	=	33.0	%	PMID[488355]
NPT306	Cell Line	PC-3	Homo sapiens	Induction	=	62.1	%	PMID[488355]
NPT15	Cell Line	Jurkat	Homo sapiens	Induction	=	94.3	%	PMID[488355]
NPT15	Cell Line	Jurkat	Homo sapiens	Induction	=	59.0	%	PMID[488355]
NPT4309	Individual Protein	Inhibitor of apoptosis protein 3	Homo sapiens	Ki	=	400.0	nM	PMID[488357]
NPT81	Cell Line	A549	Homo sapiens	IC50	=	1470.0	nM	PMID[488358]
NPT179	Cell Line	A2780	Homo sapiens	IC50	=	1790.0	nM	PMID[488358]
NPT181	Cell Line	Bel-7402	Homo sapiens	IC50	=	1660.0	nM	PMID[488358]
NPT547	Cell Line	BGC-823	Homo sapiens	IC50	=	1690.0	nM	PMID[488358]
NPT180	Cell Line	HCT-8	Homo sapiens	IC50	=	1490.0	nM	PMID[488358]
NPT149	Individual Protein	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Homo sapiens	Potency	=	3162.3	nM	PMID[488361]
NPT48	Individual Protein	Lysine-specific demethylase 4D-like	Homo sapiens	Potency	=	19952.6	nM	PMID[488359]
NPT48	Individual Protein	Lysine-specific demethylase 4D-like	Homo sapiens	Potency	=	4466.8	nM	PMID[488361]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	=	5011.9	nM	PMID[488359]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	31622.8	nM	PMID[488359]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	11220.2	nM	PMID[488361]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	39810.7	nM	PMID[488362]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	25118.9	nM	PMID[488359]
NPT213	Individual Protein	Cytochrome P450 2C19	Homo sapiens	Potency	=	39810.7	nM	PMID[488363]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	10000.0	nM	PMID[488361]
NPT583	Individual Protein	Inositol monophosphatase 1	Rattus norvegicus	Potency	=	1584.9	nM	PMID[488362]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	19952.6	nM	PMID[488361]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	39810.7	nM	PMID[488359]
NPT1119	Individual Protein	Arachidonate 12-lipoxygenase	Homo sapiens	Potency	=	8912.5	nM	PMID[488361]
NPT55	Individual Protein	Putative fructose-1,6-bisphosphate aldolase	Giardia intestinalis	Potency	=	25059.4	nM	PMID[488361]
NPT150	Individual Protein	Anthrax lethal factor	Bacillus anthracis	Potency	=	2511.9	nM	PMID[488361]
NPT150	Individual Protein	Anthrax lethal factor	Bacillus anthracis	Potency	=	12589.3	nM	PMID[488363]
NPT282	Individual Protein	MAP kinase ERK2	Homo sapiens	Potency	=	125.9	nM	PMID[488362]
NPT45	Individual Protein	Ubiquitin carboxyl-terminal hydrolase 2	Homo sapiens	Potency	=	3162.3	nM	PMID[488361]
NPT151	Individual Protein	15-hydroxyprostaglandin dehydrogenase [NAD+]	Homo sapiens	Potency	=	14125.4	nM	PMID[488362]
NPT151	Individual Protein	15-hydroxyprostaglandin dehydrogenase [NAD+]	Homo sapiens	Potency	=	25118.9	nM	PMID[488359]
NPT149	Individual Protein	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Homo sapiens	Potency	=	39810.7	nM	PMID[488361]
NPT539	Individual Protein	Cellular tumor antigen p53	Homo sapiens	Potency	=	12589.3	nM	PMID[488361]
NPT1254	Individual Protein	Streptokinase A	Streptococcus pyogenes serotype M1	EC50	=	1671.0	nM	PMID[488360]
NPT110	Individual Protein	Cytochrome P450 2D6	Homo sapiens	Potency	=	1995.3	nM	PMID[488361]
NPT110	Individual Protein	Cytochrome P450 2D6	Homo sapiens	Potency	=	31622.8	nM	PMID[488363]
NPT212	Individual Protein	Cytochrome P450 2C9	Homo sapiens	Potency	=	25118.9	nM	PMID[488363]
NPT532	Individual Protein	Lysine-specific demethylase 4A	Homo sapiens	Potency	n.a.	39810.7	nM	PMID[488362]
NPT532	Individual Protein	Lysine-specific demethylase 4A	Homo sapiens	Potency	n.a.	28183.8	nM	PMID[488360]
NPT1139	Individual Protein	Arachidonate 15-lipoxygenase, type II	Homo sapiens	Potency	n.a.	31622.8	nM	PMID[488361]
NPT110	Individual Protein	Cytochrome P450 2D6	Homo sapiens	AC50	=	1995.26	nM	PMID[488361]
NPT198	Individual Protein	Vitamin D receptor	Homo sapiens	Potency	n.a.	3162.3	nM	PMID[488362]
NPT198	Individual Protein	Vitamin D receptor	Homo sapiens	Potency	n.a.	89125.1	nM	PMID[488360]
NPT135	Individual Protein	Chromobox protein homolog 1	Homo sapiens	Potency	n.a.	17782.8	nM	PMID[488362]
NPT135	Individual Protein	Chromobox protein homolog 1	Homo sapiens	Potency	n.a.	35481.3	nM	PMID[488360]
NPT65	Cell Line	HepG2	Homo sapiens	Potency	n.a.	35481.3	nM	PMID[488360]
NPT199	Individual Protein	DNA polymerase kappa	Homo sapiens	Potency	n.a.	31622.8	nM	PMID[488364]
NPT199	Individual Protein	DNA polymerase kappa	Homo sapiens	Potency	n.a.	8912.5	nM	PMID[488365]
NPT154	Individual Protein	Mothers against decapentaplegic homolog 3	Homo sapiens	Potency	n.a.	19952.6	nM	PMID[488360]
NPT368	Cell Line	SN12C	Homo sapiens	GI50	n.a.	4731.51	nM	PMID[488366]
NPT370	Cell Line	NCI-H23	Homo sapiens	GI50	n.a.	7046.93	nM	PMID[488366]
NPT371	Cell Line	UO-31	Homo sapiens	GI50	n.a.	5559.04	nM	PMID[488366]
NPT372	Cell Line	HOP-92	Homo sapiens	GI50	n.a.	4092.61	nM	PMID[488366]
NPT116	Cell Line	HL-60	Homo sapiens	GI50	n.a.	3953.67	nM	PMID[488366]
NPT374	Cell Line	SF-539	Homo sapiens	GI50	n.a.	6760.83	nM	PMID[488366]
NPT373	Cell Line	SK-MEL-5	Homo sapiens	GI50	n.a.	4841.72	nM	PMID[488366]
NPT375	Cell Line	Malme-3M	Homo sapiens	GI50	n.a.	5807.64	nM	PMID[488366]
NPT376	Cell Line	A498	Homo sapiens	GI50	n.a.	5754.4	nM	PMID[488366]
NPT111	Cell Line	K562	Homo sapiens	GI50	n.a.	7673.61	nM	PMID[488366]
NPT377	Cell Line	OVCAR-3	Homo sapiens	GI50	n.a.	4709.77	nM	PMID[488366]
NPT112	Cell Line	MOLT-4	Homo sapiens	GI50	n.a.	6353.31	nM	PMID[488366]
NPT378	Cell Line	NCI/ADR-RES	Homo sapiens	GI50	n.a.	6266.14	nM	PMID[488366]
NPT379	Cell Line	HOP-62	Homo sapiens	GI50	n.a.	5559.04	nM	PMID[488366]
NPT380	Cell Line	U-251	Homo sapiens	GI50	n.a.	5023.43	nM	PMID[488366]
NPT382	Cell Line	OVCAR-5	Homo sapiens	GI50	n.a.	8830.8	nM	PMID[488366]
NPT381	Cell Line	OVCAR-8	Homo sapiens	GI50	n.a.	2013.72	nM	PMID[488366]
NPT383	Cell Line	SNB-19	Homo sapiens	GI50	n.a.	16292.96	nM	PMID[488366]
NPT572	Cell Line	DMS-273	Homo sapiens	GI50	n.a.	4720.63	nM	PMID[488366]
NPT323	Cell Line	SW-620	Homo sapiens	GI50	n.a.	18323.14	nM	PMID[488366]
NPT573	Cell Line	M19-MEL	Homo sapiens	GI50	n.a.	4581.42	nM	PMID[488366]
NPT455	Cell Line	NCI-H522	Homo sapiens	GI50	n.a.	8953.65	nM	PMID[488366]
NPT386	Cell Line	KM12	Homo sapiens	GI50	n.a.	6382.63	nM	PMID[488366]
NPT574	Cell Line	XF498	Homo sapiens	GI50	n.a.	7030.72	nM	PMID[488366]
NPT388	Cell Line	NCI-H322M	Homo sapiens	GI50	n.a.	7413.1	nM	PMID[488366]
NPT389	Cell Line	RPMI-8226	Homo sapiens	GI50	n.a.	3810.66	nM	PMID[488366]
NPT456	Cell Line	OVCAR-4	Homo sapiens	GI50	n.a.	10046.16	nM	PMID[488366]
NPT390	Cell Line	LOX IMVI	Homo sapiens	GI50	n.a.	7345.14	nM	PMID[488366]
NPT168	Cell Line	P388	Mus musculus	GI50	n.a.	1778.28	nM	PMID[488366]
NPT147	Cell Line	SK-MEL-2	Homo sapiens	GI50	n.a.	5105.05	nM	PMID[488366]
NPT391	Cell Line	HCC 2998	Homo sapiens	GI50	n.a.	4720.63	nM	PMID[488366]
NPT575	Cell Line	KM-20L2	Homo sapiens	GI50	n.a.	7430.19	nM	PMID[488366]
NPT81	Cell Line	A549	Homo sapiens	GI50	n.a.	4355.12	nM	PMID[488366]
NPT392	Cell Line	SNB-75	Homo sapiens	GI50	n.a.	6309.57	nM	PMID[488366]
NPT148	Cell Line	HCT-15	Homo sapiens	GI50	n.a.	5105.05	nM	PMID[488366]
NPT393	Cell Line	HCT-116	Homo sapiens	GI50	n.a.	9204.5	nM	PMID[488366]
NPT395	Cell Line	SF-268	Homo sapiens	GI50	n.a.	3917.42	nM	PMID[488366]
NPT83	Cell Line	MCF7	Homo sapiens	GI50	n.a.	7638.36	nM	PMID[488366]
NPT394	Cell Line	EKVX	Homo sapiens	GI50	n.a.	7311.39	nM	PMID[488366]
NPT576	Cell Line	DMS-114	Homo sapiens	GI50	n.a.	5470.16	nM	PMID[488366]
NPT146	Cell Line	SK-OV-3	Homo sapiens	GI50	n.a.	8433.35	nM	PMID[488366]
NPT397	Cell Line	NCI-H460	Homo sapiens	GI50	n.a.	2877.4	nM	PMID[488366]
NPT398	Cell Line	UACC-62	Homo sapiens	GI50	n.a.	4111.5	nM	PMID[488366]
NPT552	Cell Line	P388/ADR	Mus musculus	GI50	n.a.	9660.51	nM	PMID[488366]
NPT308	Cell Line	CAKI-1	Homo sapiens	GI50	n.a.	4255.98	nM	PMID[488366]
NPT458	Cell Line	IGROV-1	Homo sapiens	GI50	n.a.	6760.83	nM	PMID[488366]
NPT399	Cell Line	SF-295	Homo sapiens	GI50	n.a.	6025.6	nM	PMID[488366]
NPT403	Cell Line	UACC-257	Homo sapiens	GI50	n.a.	6165.95	nM	PMID[488366]
NPT578	Cell Line	SNB-78	Homo sapiens	GI50	n.a.	9660.51	nM	PMID[488366]
NPT404	Cell Line	CCRF-CEM	Homo sapiens	GI50	n.a.	4265.8	nM	PMID[488366]
NPT579	Cell Line	DLD-1	Homo sapiens	GI50	n.a.	8491.8	nM	PMID[488366]
NPT405	Cell Line	NCI-H226	Homo sapiens	GI50	n.a.	5248.07	nM	PMID[488366]
NPT170	Cell Line	SK-MEL-28	Homo sapiens	GI50	n.a.	6668.07	nM	PMID[488366]
NPT139	Cell Line	HT-29	Homo sapiens	GI50	n.a.	8147.04	nM	PMID[488366]
NPT406	Cell Line	RXF 393	Homo sapiens	GI50	n.a.	12941.96	nM	PMID[488366]
NPT407	Cell Line	COLO 205	Homo sapiens	GI50	n.a.	7498.94	nM	PMID[488366]
NPT732	Cell Line	HOP-18	Homo sapiens	GI50	n.a.	4581.42	nM	PMID[488366]
NPT738	Cell Line	SN12K1	Homo sapiens	GI50	n.a.	3741.11	nM	PMID[488366]
NPT1474	Individual Protein	ATP-dependent Clp protease proteolytic subunit	Bacillus subtilis (strain 168)	Potency	n.a.	10000.0	nM	PMID[488360]
NPT100	Individual Protein	Glutaminase kidney isoform, mitochondrial	Homo sapiens	Potency	n.a.	17782.8	nM	PMID[488360]
NPT243	Individual Protein	Dopamine D2 receptor	Homo sapiens	Potency	n.a.	22280.3	nM	PMID[488364]
NPT10	Individual Protein	Geminin	Homo sapiens	Potency	n.a.	103.2	nM	PMID[488360]
NPT66	Individual Protein	Acetylcholinesterase	Electrophorus electricus	Inhibition	=	-17.87	%	PMID[488367]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	n.a.	29092.9	nM	PMID[488360]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	n.a.	18356.4	nM	PMID[488360]
NPT2268	Cell Line	DOK	Homo sapiens	IC50	=	11797.98	nM	PMID[488371]
NPT1899	Cell Line	DSH1	Homo sapiens	IC50	=	763524.34	nM	PMID[488371]
NPT4600	Cell Line	DV-90	Homo sapiens	IC50	=	29927.18	nM	PMID[488371]
NPT1184	Cell Line	Daoy	Homo sapiens	IC50	=	5464.66	nM	PMID[488371]
NPT90	Cell Line	DU-145	Homo sapiens	IC50	=	8759.36	nM	PMID[488371]
NPT1900	Cell Line	DU-4475	Homo sapiens	IC50	=	13242.03	nM	PMID[488371]
NPT4601	Cell Line	EHEB	Homo sapiens	IC50	=	34552.95	nM	PMID[488371]
NPT394	Cell Line	EKVX	Homo sapiens	IC50	=	46895.7	nM	PMID[488371]
NPT1901	Cell Line	EM-2	Homo sapiens	IC50	=	36132.98	nM	PMID[488371]
NPT1902	Cell Line	ES1	Homo sapiens	IC50	=	7811.3	nM	PMID[488371]
NPT1905	Cell Line	ES4	Homo sapiens	IC50	=	4517.46	nM	PMID[488371]
NPT1903	Cell Line	ES5	Homo sapiens	IC50	=	304338.63	nM	PMID[488371]
NPT1904	Cell Line	ES3	Homo sapiens	IC50	=	15355.63	nM	PMID[488371]
NPT464	Cell Line	Daudi	Homo sapiens	IC50	=	5749.14	nM	PMID[488371]
NPT2270	Cell Line	Detroit562	Homo sapiens	IC50	=	11470.21	nM	PMID[488371]
NPT2271	Cell Line	DoTc2-4510	Homo sapiens	IC50	=	14246.07	nM	PMID[488371]
NPT1906	Cell Line	EB-3	Homo sapiens	IC50	=	20778.4	nM	PMID[488371]
NPT1907	Cell Line	EB2	Homo sapiens	IC50	=	6167.73	nM	PMID[488371]
NPT1908	Cell Line	EC-GI-10	Homo sapiens	IC50	=	246819.67	nM	PMID[488371]
NPT1910	Cell Line	ECC4	Homo sapiens	IC50	=	23824.37	nM	PMID[488371]
NPT4602	Cell Line	EFE-184	Homo sapiens	IC50	=	26116.86	nM	PMID[488371]
NPT2272	Cell Line	EFM-19	Homo sapiens	IC50	=	4910.9	nM	PMID[488371]
NPT2273	Cell Line	EFO-21	Homo sapiens	IC50	=	15580.78	nM	PMID[488371]
NPT2274	Cell Line	EFO-27	Homo sapiens	IC50	=	88833.16	nM	PMID[488371]
NPT2275	Cell Line	EGI-1	Homo sapiens	IC50	=	23076.3	nM	PMID[488371]
NPT376	Cell Line	A498	Homo sapiens	IC50	=	356141.81	nM	PMID[488371]
NPT2276	Cell Line	A673	Homo sapiens	IC50	=	12633.18	nM	PMID[488371]
NPT1081	Cell Line	BXPC-3	Homo sapiens	IC50	=	6414.76	nM	PMID[488371]
NPT2277	Cell Line	C-33-A	Homo sapiens	IC50	=	80386.96	nM	PMID[488371]
NPT4603	Cell Line	C-4-II	Homo sapiens	IC50	=	36295.69	nM	PMID[488371]
NPT2279	Cell Line	COLO-792	Homo sapiens	IC50	=	500382.6	nM	PMID[488371]
NPT1912	Cell Line	COLO-800	Homo sapiens	IC50	=	43189.83	nM	PMID[488371]
NPT1189	Cell Line	DG-75	Homo sapiens	IC50	=	1178223.41	nM	PMID[488371]
NPT1913	Cell Line	DJM-1	Homo sapiens	IC50	=	8802.57	nM	PMID[488371]
NPT2280	Cell Line	A704	Homo sapiens	IC50	=	10855.62	nM	PMID[488371]
NPT2281	Cell Line	ABC-1	Homo sapiens	IC50	=	164690.01	nM	PMID[488371]
NPT1911	Cell Line	C2BBe1	Homo sapiens	IC50	=	13934.6	nM	PMID[488371]
NPT2282	Cell Line	C32	Homo sapiens	IC50	=	2825.82	nM	PMID[488371]
NPT2284	Cell Line	C3A	Homo sapiens	IC50	=	15374.26	nM	PMID[488371]
NPT1914	Cell Line	COLO-824	Homo sapiens	IC50	=	42107.8	nM	PMID[488371]
NPT2283	Cell Line	DK-MG	Homo sapiens	IC50	=	1132138.95	nM	PMID[488371]
NPT576	Cell Line	DMS-114	Homo sapiens	IC50	=	34154.35	nM	PMID[488371]
NPT369	Cell Line	ACHN	Homo sapiens	IC50	=	50992.06	nM	PMID[488371]
NPT1916	Cell Line	ACN	Homo sapiens	IC50	=	5855.35	nM	PMID[488371]
NPT1452	Cell Line	C8166	Homo sapiens	IC50	=	7644.26	nM	PMID[488371]
NPT1915	Cell Line	COLO-829	Homo sapiens	IC50	=	5290.16	nM	PMID[488371]
NPT2285	Cell Line	COR-L105	Homo sapiens	IC50	=	22343.74	nM	PMID[488371]
NPT2287	Cell Line	COR-L23	Homo sapiens	IC50	=	9629.13	nM	PMID[488371]
NPT1918	Cell Line	DMS-79	Homo sapiens	IC50	=	789116.53	nM	PMID[488371]
NPT1919	Cell Line	DOHH-2	Homo sapiens	IC50	=	7573.63	nM	PMID[488371]
NPT196	Cell Line	AGS	Homo sapiens	IC50	=	8626.28	nM	PMID[488371]
NPT1920	Cell Line	ALL-PO	Homo sapiens	IC50	=	3646.64	nM	PMID[488371]
NPT1917	Cell Line	CA46	Homo sapiens	IC50	=	18700.83	nM	PMID[488371]
NPT308	Cell Line	CAKI-1	Homo sapiens	IC50	=	61922.9	nM	PMID[488371]
NPT2286	Cell Line	CAL-120	Homo sapiens	IC50	=	24049.93	nM	PMID[488371]
NPT1921	Cell Line	COR-L279	Homo sapiens	IC50	=	58844.71	nM	PMID[488371]
NPT1922	Cell Line	COR-L88	Homo sapiens	IC50	=	39562.71	nM	PMID[488371]
NPT1923	Cell Line	DMS-153	Homo sapiens	IC50	=	37280.63	nM	PMID[488371]
NPT572	Cell Line	DMS-273	Homo sapiens	IC50	=	4059.4	nM	PMID[488371]
NPT4604	Cell Line	DMS-53	Homo sapiens	IC50	=	15529.94	nM	PMID[488371]
NPT1924	Cell Line	AM-38	Homo sapiens	IC50	=	12458.17	nM	PMID[488371]
NPT2288	Cell Line	AN3-CA	Homo sapiens	IC50	=	6246.27	nM	PMID[488371]
NPT2289	Cell Line	CAL-12T	Homo sapiens	IC50	=	9732.11	nM	PMID[488371]
NPT1925	Cell Line	CAL-148	Homo sapiens	IC50	=	74922.86	nM	PMID[488371]
NPT2290	Cell Line	CAL-27	Homo sapiens	IC50	=	13102.37	nM	PMID[488371]
NPT2291	Cell Line	CP50-MEL-B	Homo sapiens	IC50	=	384399.74	nM	PMID[488371]
NPT1926	Cell Line	CP66-MEL	Homo sapiens	IC50	=	4505.28	nM	PMID[488371]
NPT1629	Cell Line	CWR22R	Homo sapiens	IC50	=	22543.46	nM	PMID[488371]
NPT1927	Cell Line	ARH-77	Homo sapiens	IC50	=	16351.75	nM	PMID[488371]
NPT1928	Cell Line	ATN-1	Homo sapiens	IC50	=	55443.81	nM	PMID[488371]
NPT2296	Cell Line	AU565	Homo sapiens	IC50	=	9909.27	nM	PMID[488371]
NPT2292	Cell Line	CAL-33	Homo sapiens	IC50	=	22901.22	nM	PMID[488371]
NPT2293	Cell Line	CAL-39	Homo sapiens	IC50	=	4479.27	nM	PMID[488371]
NPT1929	Cell Line	CPC-N	Homo sapiens	IC50	=	499299.44	nM	PMID[488371]
NPT1930	Cell Line	CTB-1	Homo sapiens	IC50	=	28030.91	nM	PMID[488371]
NPT2294	Cell Line	23132-87	Homo sapiens	IC50	=	23296.19	nM	PMID[488371]
NPT2295	Cell Line	5637	Homo sapiens	IC50	=	13229.68	nM	PMID[488371]
NPT2297	Cell Line	ASPC1	Homo sapiens	IC50	=	55661.85	nM	PMID[488371]
NPT2299	Cell Line	CAL-51	Homo sapiens	IC50	=	5368.65	nM	PMID[488371]
NPT2300	Cell Line	CAL-54	Homo sapiens	IC50	=	20388.79	nM	PMID[488371]
NPT2301	Cell Line	CAL-62	Homo sapiens	IC50	=	23271.7	nM	PMID[488371]
NPT1932	Cell Line	CTV-1	Homo sapiens	IC50	=	9370.95	nM	PMID[488371]
NPT1933	Cell Line	CW-2	Homo sapiens	IC50	=	6184886.91	nM	PMID[488371]
NPT2302	Cell Line	639-V	Homo sapiens	IC50	=	173891.75	nM	PMID[488371]
NPT2303	Cell Line	647-V	Homo sapiens	IC50	=	24543.03	nM	PMID[488371]
NPT1094	Cell Line	697	Homo sapiens	IC50	=	42864.59	nM	PMID[488371]
NPT1931	Cell Line	BB30-HNC	Homo sapiens	IC50	=	5060.53	nM	PMID[488371]
NPT1934	Cell Line	BB49-HNC	Homo sapiens	IC50	=	75453.53	nM	PMID[488371]
NPT2304	Cell Line	CAL-72	Homo sapiens	IC50	=	10377.25	nM	PMID[488371]
NPT2305	Cell Line	CAL-85-1	Homo sapiens	IC50	=	7810.52	nM	PMID[488371]
NPT2306	Cell Line	Ca-Ski	Homo sapiens	IC50	=	18205.54	nM	PMID[488371]
NPT1031	Cell Line	Ca9-22	Homo sapiens	IC50	=	12437.67	nM	PMID[488371]
NPT2307	Cell Line	769-P	Homo sapiens	IC50	=	8470.44	nM	PMID[488371]
NPT401	Cell Line	786-0	Homo sapiens	IC50	=	8642.13	nM	PMID[488371]
NPT1935	Cell Line	BB65-RCC	Homo sapiens	IC50	=	11360.07	nM	PMID[488371]
NPT929	Cell Line	BC1 cell line		IC50	=	5025.16	nM	PMID[488371]
NPT2308	Cell Line	CAMA-1	Homo sapiens	IC50	=	7091.9	nM	PMID[488371]
NPT2309	Cell Line	CAPAN-1	Homo sapiens	IC50	=	9012.09	nM	PMID[488371]
NPT2310	Cell Line	CaR-1	Homo sapiens	IC50	=	35631.46	nM	PMID[488371]
NPT1307	Cell Line	Calu-1	Homo sapiens	IC50	=	17135.15	nM	PMID[488371]
NPT2311	Cell Line	Calu-3	Homo sapiens	IC50	=	8453.68	nM	PMID[488371]
NPT1939	Cell Line	8-MG-BA	Homo sapiens	IC50	=	3532.08	nM	PMID[488371]
NPT2312	Cell Line	8305C	Homo sapiens	IC50	=	25656.66	nM	PMID[488371]
NPT1936	Cell Line	BC-3	Homo sapiens	IC50	=	75748.68	nM	PMID[488371]
NPT2313	Cell Line	BCPAP	Homo sapiens	IC50	=	13692.65	nM	PMID[488371]
NPT1940	Cell Line	BE-13	Homo sapiens	IC50	=	22940.39	nM	PMID[488371]
NPT1937	Cell Line	CAS-1	Homo sapiens	IC50	=	15279.15	nM	PMID[488371]
NPT4605	Cell Line	CCF-STTG1	Homo sapiens	IC50	=	13953.41	nM	PMID[488371]
NPT404	Cell Line	CCRF-CEM	Homo sapiens	IC50	=	3016.18	nM	PMID[488371]
NPT1938	Cell Line	Calu-6	Homo sapiens	IC50	=	4834.56	nM	PMID[488371]
NPT4458	Cell Line	Caov-3 cell line		IC50	=	37484.14	nM	PMID[488371]
NPT1313	Cell Line	Capan-2	Homo sapiens	IC50	=	18252.55	nM	PMID[488371]
NPT1215	Cell Line	8505C	Homo sapiens	IC50	=	14068.45	nM	PMID[488371]
NPT1941	Cell Line	A101D	Homo sapiens	IC50	=	6365.86	nM	PMID[488371]
NPT2314	Cell Line	BEN	Homo sapiens	IC50	=	39347.21	nM	PMID[488371]
NPT2315	Cell Line	BFTC-905	Homo sapiens	IC50	=	5029.55	nM	PMID[488371]
NPT1942	Cell Line	CESS	Homo sapiens	IC50	=	6242.77	nM	PMID[488371]
NPT1943	Cell Line	CGTH-W-1	Homo sapiens	IC50	=	16772.36	nM	PMID[488371]
NPT2317	Cell Line	ChaGo-K-1	Homo sapiens	IC50	=	7075.8	nM	PMID[488371]
NPT2318	Cell Line	A172	Homo sapiens	IC50	=	8775.31	nM	PMID[488371]
NPT2319	Cell Line	A204	Homo sapiens	IC50	=	17366.86	nM	PMID[488371]
NPT1383	Cell Line	A2058	Homo sapiens	IC50	=	2321.85	nM	PMID[488371]
NPT2320	Cell Line	BFTC-909	Homo sapiens	IC50	=	68067.85	nM	PMID[488371]
NPT2321	Cell Line	BHT-101	Homo sapiens	IC50	=	20014.28	nM	PMID[488371]
NPT2323	Cell Line	BHY	Homo sapiens	IC50	=	6032.66	nM	PMID[488371]
NPT2322	Cell Line	CHL-1	Homo sapiens	IC50	=	4695.48	nM	PMID[488371]
NPT1945	Cell Line	CHP-126	Homo sapiens	IC50	=	39275.86	nM	PMID[488371]
NPT1946	Cell Line	D-263MG	Homo sapiens	IC50	=	97035.32	nM	PMID[488371]
NPT1947	Cell Line	D283 Med		IC50	=	14690.59	nM	PMID[488371]
NPT1948	Cell Line	A253 cell line		IC50	=	7746.86	nM	PMID[488371]
NPT179	Cell Line	A2780	Homo sapiens	IC50	=	13225.79	nM	PMID[488371]
NPT1949	Cell Line	BL-41	Homo sapiens	IC50	=	5496.48	nM	PMID[488371]
NPT1950	Cell Line	BL-70	Homo sapiens	IC50	=	5829.77	nM	PMID[488371]
NPT2324	Cell Line	CHP-212	Homo sapiens	IC50	=	3121.54	nM	PMID[488371]
NPT1951	Cell Line	CMK	Homo sapiens	IC50	=	10682.27	nM	PMID[488371]
NPT407	Cell Line	COLO 205	Homo sapiens	IC50	=	3867.4	nM	PMID[488371]
NPT1954	Cell Line	D-392MG	Homo sapiens	IC50	=	16574.78	nM	PMID[488371]
NPT1955	Cell Line	A3-KAW	Homo sapiens	IC50	=	9005.73	nM	PMID[488371]
NPT1083	Cell Line	A-375	Homo sapiens	IC50	=	3572.46	nM	PMID[488371]
NPT4606	Cell Line	BOKU	Homo sapiens	IC50	=	10702.38	nM	PMID[488371]
NPT2325	Cell Line	BPH-1	Homo sapiens	IC50	=	100905.86	nM	PMID[488371]
NPT2326	Cell Line	BT-20	Homo sapiens	IC50	=	14473.94	nM	PMID[488371]
NPT1952	Cell Line	COLO-320-HSR	Homo sapiens	IC50	=	17127.84	nM	PMID[488371]
NPT1956	Cell Line	COLO-668	Homo sapiens	IC50	=	60663.67	nM	PMID[488371]
NPT1957	Cell Line	D-502MG	Homo sapiens	IC50	=	340359.02	nM	PMID[488371]
NPT1958	Cell Line	A388	Homo sapiens	IC50	=	6703.11	nM	PMID[488371]
NPT1959	Cell Line	A4-Fuk	Homo sapiens	IC50	=	49498.09	nM	PMID[488371]
NPT845	Cell Line	BT-474	Homo sapiens	IC50	=	35238.88	nM	PMID[488371]
NPT2328	Cell Line	COLO-678	Homo sapiens	IC50	=	729658.78	nM	PMID[488371]
NPT2329	Cell Line	COLO-679	Homo sapiens	IC50	=	4197.91	nM	PMID[488371]
NPT2332	Cell Line	COLO-680N	Homo sapiens	IC50	=	19369.53	nM	PMID[488371]
NPT1961	Cell Line	D-542MG	Homo sapiens	IC50	=	3126.31	nM	PMID[488371]
NPT1962	Cell Line	DB	Homo sapiens	IC50	=	177016.69	nM	PMID[488371]
NPT2331	Cell Line	A-427	Homo sapiens	IC50	=	34312.2	nM	PMID[488371]
NPT762	Cell Line	A-431	Homo sapiens	IC50	=	5758.68	nM	PMID[488371]
NPT1960	Cell Line	BV-173	Homo sapiens	IC50	=	702352.21	nM	PMID[488371]
NPT1963	Cell Line	Becker	Homo sapiens	IC50	=	15754.63	nM	PMID[488371]
NPT1964	Cell Line	COLO-684	Homo sapiens	IC50	=	20616.75	nM	PMID[488371]
NPT2278	Cell Line	COLO-741	Homo sapiens	IC50	=	7420.84	nM	PMID[488371]
NPT2333	Cell Line	DBTRG-05MG	Homo sapiens	IC50	=	15406.54	nM	PMID[488371]
NPT1965	Cell Line	DEL	Homo sapiens	IC50	=	10439.93	nM	PMID[488371]
NPT1966	Cell Line	NCI-H1838	Homo sapiens	IC50	=	1899686.21	nM	PMID[488371]
NPT2198	Cell Line	NCI-H524	Homo sapiens	IC50	=	95772.64	nM	PMID[488371]
NPT1967	Cell Line	NCI-H526	Homo sapiens	IC50	=	39654.92	nM	PMID[488371]
NPT2335	Cell Line	NCI-H596		IC50	=	15389.99	nM	PMID[488371]
NPT2336	Cell Line	OE19	Homo sapiens	IC50	=	29703.27	nM	PMID[488371]
NPT2337	Cell Line	OE33	Homo sapiens	IC50	=	13253.2	nM	PMID[488371]
NPT2200	Cell Line	RPMI-6666	Homo sapiens	IC50	=	8674.34	nM	PMID[488371]
NPT1091	Cell Line	RPMI-7951	Homo sapiens	IC50	=	25575.17	nM	PMID[488371]
NPT389	Cell Line	RPMI-8226	Homo sapiens	IC50	=	13733.79	nM	PMID[488371]
NPT311	Cell Line	SK-LU-1	Homo sapiens	IC50	=	7211.59	nM	PMID[488371]
NPT926	Cell Line	SK-MEL-1	Homo sapiens	IC50	=	512251.65	nM	PMID[488371]
NPT1312	Cell Line	SW1990	Homo sapiens	IC50	=	6485.48	nM	PMID[488371]
NPT2338	Cell Line	SW48	Homo sapiens	IC50	=	31057.89	nM	PMID[488371]
NPT323	Cell Line	SW-620	Homo sapiens	IC50	=	28750.18	nM	PMID[488371]
NPT1969	Cell Line	TGW	Homo sapiens	IC50	=	81818.55	nM	PMID[488371]
NPT1970	Cell Line	THP-1	Homo sapiens	IC50	=	29770.38	nM	PMID[488371]
NPT1971	Cell Line	GI-1	Homo sapiens	IC50	=	3763.48	nM	PMID[488371]
NPT1972	Cell Line	GI-ME-N	Homo sapiens	IC50	=	89408.52	nM	PMID[488371]
NPT2204	Cell Line	HH	Homo sapiens	IC50	=	36068.21	nM	PMID[488371]
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	8847.17	nM	PMID[488371]
NPT1973	Cell Line	IST-SL1	Homo sapiens	IC50	=	42654.42	nM	PMID[488371]
NPT1975	Cell Line	KS-1	Homo sapiens	IC50	=	14490.39	nM	PMID[488371]
NPT2340	Cell Line	KU-19-19	Homo sapiens	IC50	=	396071.99	nM	PMID[488371]
NPT1976	Cell Line	LNCaP-Clone-FGC	Homo sapiens	IC50	=	21921.77	nM	PMID[488371]
NPT2209	Cell Line	MFH-ino	Homo sapiens	IC50	=	5584.14	nM	PMID[488371]
NPT1978	Cell Line	MFM-223	Homo sapiens	IC50	=	76978.18	nM	PMID[488371]
NPT1979	Cell Line	NB13	Homo sapiens	IC50	=	16712.45	nM	PMID[488371]
NPT639	Cell Line	NCI-H187	Homo sapiens	IC50	=	78480.09	nM	PMID[488371]
NPT1981	Cell Line	NCI-H1882	Homo sapiens	IC50	=	34517.24	nM	PMID[488371]
NPT1982	Cell Line	NCI-H1963	Homo sapiens	IC50	=	46315.38	nM	PMID[488371]
NPT1983	Cell Line	NCI-H64	Homo sapiens	IC50	=	59099.12	nM	PMID[488371]
NPT2343	Cell Line	NCI-H650	Homo sapiens	IC50	=	16444.09	nM	PMID[488371]
NPT1968	Cell Line	OMC-1	Homo sapiens	IC50	=	12079.19	nM	PMID[488371]
NPT1984	Cell Line	ONS-76	Homo sapiens	IC50	=	8451.18	nM	PMID[488371]
NPT1986	Cell Line	RPMI 8402	Homo sapiens	IC50	=	4054.37	nM	PMID[488371]
NPT1987	Cell Line	RPMI-8866	Homo sapiens	IC50	=	8097.31	nM	PMID[488371]
NPT147	Cell Line	SK-MEL-2	Homo sapiens	IC50	=	11739.44	nM	PMID[488371]
NPT2344	Cell Line	SK-MEL-24	Homo sapiens	IC50	=	4670.28	nM	PMID[488371]
NPT170	Cell Line	SK-MEL-28	Homo sapiens	IC50	=	8483.92	nM	PMID[488371]
NPT2345	Cell Line	SW626	Homo sapiens	IC50	=	9353.02	nM	PMID[488371]
NPT1988	Cell Line	SW684	Homo sapiens	IC50	=	162457.43	nM	PMID[488371]
NPT384	Cell Line	TK-10	Homo sapiens	IC50	=	37398.33	nM	PMID[488371]
NPT4607	Cell Line	TT	Homo sapiens	IC50	=	23528.23	nM	PMID[488371]
NPT2347	Cell Line	GMS-10	Homo sapiens	IC50	=	23037.86	nM	PMID[488371]
NPT1989	Cell Line	GOTO	Homo sapiens	IC50	=	23568.59	nM	PMID[488371]
NPT2348	Cell Line	HLE	Homo sapiens	IC50	=	5928.52	nM	PMID[488371]
NPT2349	Cell Line	HMV-2 cell line		IC50	=	4611.44	nM	PMID[488371]
NPT2350	Cell Line	HN	Homo sapiens	IC50	=	24833.54	nM	PMID[488371]
NPT1974	Cell Line	IST-SL2	Homo sapiens	IC50	=	49822.66	nM	PMID[488371]
NPT1990	Cell Line	J-RT3-T3-5	Homo sapiens	IC50	=	6085.28	nM	PMID[488371]
NPT1505	Cell Line	J82	Homo sapiens	IC50	=	11827.31	nM	PMID[488371]
NPT1991	Cell Line	KU812 cell line		IC50	=	124231.03	nM	PMID[488371]
NPT1992	Cell Line	KURAMOCHI	Homo sapiens	IC50	=	7055.79	nM	PMID[488371]
NPT1977	Cell Line	LOUCY	Homo sapiens	IC50	=	5099.23	nM	PMID[488371]
NPT390	Cell Line	LOX IMVI	Homo sapiens	IC50	=	17485.36	nM	PMID[488371]
NPT1993	Cell Line	LP-1	Homo sapiens	IC50	=	63863.56	nM	PMID[488371]
NPT2351	Cell Line	MG-63	Homo sapiens	IC50	=	9637.34	nM	PMID[488371]
NPT1994	Cell Line	MHH-CALL-2	Homo sapiens	IC50	=	217408.7	nM	PMID[488371]
NPT2352	Cell Line	MHH-ES-1	Homo sapiens	IC50	=	15847.22	nM	PMID[488371]
NPT1996	Cell Line	NB5	Homo sapiens	IC50	=	22356.86	nM	PMID[488371]
NPT2353	Cell Line	NCI-H1993	Homo sapiens	IC50	=	66766.94	nM	PMID[488371]
NPT2354	Cell Line	NCI-H2009	Homo sapiens	IC50	=	11910.29	nM	PMID[488371]
NPT2356	Cell Line	NCI-H661	Homo sapiens	IC50	=	19184.74	nM	PMID[488371]
NPT1396	Cell Line	NCI-H69	Homo sapiens	IC50	=	49559.2	nM	PMID[488371]
NPT1985	Cell Line	OPM-2	Homo sapiens	IC50	=	75170.21	nM	PMID[488371]
NPT1997	Cell Line	OS-RC-2	Homo sapiens	IC50	=	9344.36	nM	PMID[488371]
NPT377	Cell Line	OVCAR-3	Homo sapiens	IC50	=	23607.49	nM	PMID[488371]
NPT1998	Cell Line	RS4-11	Homo sapiens	IC50	=	10531.34	nM	PMID[488371]
NPT2357	Cell Line	RT-112	Homo sapiens	IC50	=	12593.33	nM	PMID[488371]
NPT2358	Cell Line	SK-MEL3	Homo sapiens	IC50	=	16194.17	nM	PMID[488371]
NPT2359	Cell Line	SK-MEL-30	Homo sapiens	IC50	=	12795.2	nM	PMID[488371]
NPT2360	Cell Line	SW756	Homo sapiens	IC50	=	53232.49	nM	PMID[488371]
NPT2361	Cell Line	SW780	Homo sapiens	IC50	=	312654.58	nM	PMID[488371]
NPT1999	Cell Line	TUR	Homo sapiens	IC50	=	36690.32	nM	PMID[488371]
NPT2362	Cell Line	TYK-nu	Homo sapiens	IC50	=	22630.06	nM	PMID[488371]
NPT2363	Cell Line	U-118-MG	Homo sapiens	IC50	=	29144.23	nM	PMID[488371]
NPT2364	Cell Line	GP5d	Homo sapiens	IC50	=	8602.17	nM	PMID[488371]
NPT2000	Cell Line	GR-ST	Homo sapiens	IC50	=	5798.49	nM	PMID[488371]
NPT2365	Cell Line	HO-1-N-1	Homo sapiens	IC50	=	12285.32	nM	PMID[488371]
NPT379	Cell Line	HOP-62	Homo sapiens	IC50	=	5691.89	nM	PMID[488371]
NPT2001	Cell Line	JAR	Homo sapiens	IC50	=	642312.54	nM	PMID[488371]
NPT2366	Cell Line	JEG-3	Homo sapiens	IC50	=	16763.85	nM	PMID[488371]
NPT2002	Cell Line	KY821	Homo sapiens	IC50	=	207787.72	nM	PMID[488371]
NPT2367	Cell Line	KYSE-140	Homo sapiens	IC50	=	5038.94	nM	PMID[488371]
NPT2003	Cell Line	LS-1034	Homo sapiens	IC50	=	57283.64	nM	PMID[488371]
NPT2004	Cell Line	LS-123	Homo sapiens	IC50	=	9418.44	nM	PMID[488371]
NPT2005	Cell Line	MHH-NB-11	Homo sapiens	IC50	=	37860.41	nM	PMID[488371]
NPT2006	Cell Line	MHH-PREB-1	Homo sapiens	IC50	=	10859.49	nM	PMID[488371]
NPT2007	Cell Line	NB6	Homo sapiens	IC50	=	219092.5	nM	PMID[488371]
NPT2368	Cell Line	NCI-H2030	Homo sapiens	IC50	=	12694.73	nM	PMID[488371]
NPT2369	Cell Line	NCI-H2052	Homo sapiens	IC50	=	8532.03	nM	PMID[488371]
NPT2010	Cell Line	NCI-H716	Homo sapiens	IC50	=	231517.62	nM	PMID[488371]
NPT2011	Cell Line	NCI-H719	Homo sapiens	IC50	=	183573.66	nM	PMID[488371]
NPT2012	Cell Line	NCI-H720	Homo sapiens	IC50	=	3722932.71	nM	PMID[488371]
NPT456	Cell Line	OVCAR-4	Homo sapiens	IC50	=	12292.34	nM	PMID[488371]
NPT382	Cell Line	OVCAR-5	Homo sapiens	IC50	=	248352.97	nM	PMID[488371]
NPT4608	Cell Line	RT-4	Homo sapiens	IC50	=	85566.08	nM	PMID[488371]
NPT2370	Cell Line	RVH-421	Homo sapiens	IC50	=	11507.65	nM	PMID[488371]
NPT406	Cell Line	RXF 393	Homo sapiens	IC50	=	40164.84	nM	PMID[488371]
NPT1506	Cell Line	SK-MES-1	Homo sapiens	IC50	=	5011.74	nM	PMID[488371]
NPT2013	Cell Line	SK-MM-2	Homo sapiens	IC50	=	190544.93	nM	PMID[488371]
NPT2371	Cell Line	SW837	Homo sapiens	IC50	=	17990.86	nM	PMID[488371]
NPT2014	Cell Line	SW872	Homo sapiens	IC50	=	16227.41	nM	PMID[488371]
NPT1045	Cell Line	U2OS	Homo sapiens	IC50	=	899051.21	nM	PMID[488371]
NPT2015	Cell Line	U-266	Homo sapiens	IC50	=	33308.95	nM	PMID[488371]
NPT2016	Cell Line	ES6	Homo sapiens	IC50	=	9549.17	nM	PMID[488371]
NPT2017	Cell Line	ES7	Homo sapiens	IC50	=	6601.1	nM	PMID[488371]
NPT2018	Cell Line	GT3TKB	Homo sapiens	IC50	=	3619.93	nM	PMID[488371]
NPT372	Cell Line	HOP-92	Homo sapiens	IC50	=	7879.95	nM	PMID[488371]
NPT307	Cell Line	HOS	Homo sapiens	IC50	=	15268.49	nM	PMID[488371]
NPT2019	Cell Line	JVM-2	Homo sapiens	IC50	=	2827304.32	nM	PMID[488371]
NPT2020	Cell Line	JVM-3	Homo sapiens	IC50	=	138298.86	nM	PMID[488371]
NPT2373	Cell Line	KYSE-150 cell line		IC50	=	12084.48	nM	PMID[488371]
NPT2374	Cell Line	KYSE-180	Homo sapiens	IC50	=	7583.96	nM	PMID[488371]
NPT2021	Cell Line	LS-411N	Homo sapiens	IC50	=	7489.77	nM	PMID[488371]
NPT783	Cell Line	MIA PaCa-2	Homo sapiens	IC50	=	4699.87	nM	PMID[488371]
NPT2375	Cell Line	MKN-1	Homo sapiens	IC50	=	12301.55	nM	PMID[488371]
NPT2008	Cell Line	NB69	Homo sapiens	IC50	=	265032.38	nM	PMID[488371]
NPT2009	Cell Line	NCI-H2081	Homo sapiens	IC50	=	64616.97	nM	PMID[488371]
NPT2377	Cell Line	NCI-H2087	Homo sapiens	IC50	=	5445.21	nM	PMID[488371]
NPT2024	Cell Line	NCI-H209	Homo sapiens	IC50	=	32994.17	nM	PMID[488371]
NPT2378	Cell Line	NCI-H727	Homo sapiens	IC50	=	7881.1	nM	PMID[488371]
NPT2025	Cell Line	NCI-H747	Homo sapiens	IC50	=	14269.48	nM	PMID[488371]
NPT381	Cell Line	OVCAR-8	Homo sapiens	IC50	=	11329.75	nM	PMID[488371]
NPT2379	Cell Line	P12-Ichikawa	Homo sapiens	IC50	=	9449.58	nM	PMID[488371]
NPT80	Cell Line	Raji	Homo sapiens	IC50	=	10518.34	nM	PMID[488371]
NPT2026	Cell Line	Ramos-2G6-4C10	Homo sapiens	IC50	=	17000.66	nM	PMID[488371]
NPT2380	Cell Line	SK-N-AS	Homo sapiens	IC50	=	13828.17	nM	PMID[488371]
NPT2027	Cell Line	SK-N-DZ	Homo sapiens	IC50	=	60877.22	nM	PMID[488371]
NPT2382	Cell Line	SW948	Homo sapiens	IC50	=	148791.95	nM	PMID[488371]
NPT2030	Cell Line	U-698-M	Homo sapiens	IC50	=	25150.61	nM	PMID[488371]
NPT1535	Cell Line	U-87 MG	Homo sapiens	IC50	=	41534.32	nM	PMID[488371]
NPT2031	Cell Line	ES8	Homo sapiens	IC50	=	14048.52	nM	PMID[488371]
NPT2383	Cell Line	ESS-1	Homo sapiens	IC50	=	9421.48	nM	PMID[488371]
NPT2891	Cell Line	H4	Homo sapiens	IC50	=	4131.39	nM	PMID[488371]
NPT2032	Cell Line	HAL-01	Homo sapiens	IC50	=	25784.15	nM	PMID[488371]
NPT2384	Cell Line	HPAF-II	Homo sapiens	IC50	=	25364.08	nM	PMID[488371]
NPT924	Cell Line	HSC-2	Homo sapiens	IC50	=	7399.86	nM	PMID[488371]
NPT2385	Cell Line	HSC-3	Homo sapiens	IC50	=	23864.4	nM	PMID[488371]
NPT2033	Cell Line	JIYOYE	Homo sapiens	IC50	=	6941.97	nM	PMID[488371]
NPT111	Cell Line	K562	Homo sapiens	IC50	=	31724.65	nM	PMID[488371]
NPT2386	Cell Line	KYSE-270	Homo sapiens	IC50	=	8855.71	nM	PMID[488371]
NPT2387	Cell Line	KYSE-410	Homo sapiens	IC50	=	6378.32	nM	PMID[488371]
NPT2395	Cell Line	KYSE-450	Homo sapiens	IC50	=	17716.09	nM	PMID[488371]
NPT2022	Cell Line	LS-513	Homo sapiens	IC50	=	44262.51	nM	PMID[488371]
NPT2034	Cell Line	LU-134-A	Homo sapiens	IC50	=	932745.14	nM	PMID[488371]
NPT1179	Cell Line	MKN-28	Homo sapiens	IC50	=	10012.51	nM	PMID[488371]
NPT1097	Cell Line	MKN-45	Homo sapiens	IC50	=	7979.31	nM	PMID[488371]
NPT2398	Cell Line	MKN-7	Homo sapiens	IC50	=	33160.35	nM	PMID[488371]
NPT2035	Cell Line	NCCIT	Homo sapiens	IC50	=	19185.08	nM	PMID[488371]
NPT2036	Cell Line	NCI-H1092	Homo sapiens	IC50	=	49716.21	nM	PMID[488371]
NPT2390	Cell Line	NCI-H2122	Homo sapiens	IC50	=	2810.07	nM	PMID[488371]
NPT1082	Cell Line	NCI-H2126	Homo sapiens	IC50	=	27850.17	nM	PMID[488371]
NPT2038	Cell Line	NCI-H748	Homo sapiens	IC50	=	1798515.71	nM	PMID[488371]
NPT2391	Cell Line	NCI-H810	Homo sapiens	IC50	=	7731.43	nM	PMID[488371]
NPT2040	Cell Line	P30-OHK	Homo sapiens	IC50	=	6130.2	nM	PMID[488371]
NPT2041	Cell Line	P31-FUJ	Homo sapiens	IC50	=	368765.15	nM	PMID[488371]
NPT2400	Cell Line	PA-1	Homo sapiens	IC50	=	2321.84	nM	PMID[488371]
NPT2392	Cell Line	S-117	Homo sapiens	IC50	=	3629.58	nM	PMID[488371]
NPT2393	Cell Line	SAS	Homo sapiens	IC50	=	16808.94	nM	PMID[488371]
NPT2028	Cell Line	SK-N-FI	Homo sapiens	IC50	=	239545.17	nM	PMID[488371]
NPT2043	Cell Line	SK-NEP-1	Homo sapiens	IC50	=	15074.02	nM	PMID[488371]
NPT2029	Cell Line	SW 954	Homo sapiens	IC50	=	31080.01	nM	PMID[488371]
NPT2044	Cell Line	SW 962	Homo sapiens	IC50	=	7765.94	nM	PMID[488371]
NPT371	Cell Line	UO-31	Homo sapiens	IC50	=	19146.83	nM	PMID[488371]
NPT380	Cell Line	U-251	Homo sapiens	IC50	=	9692.08	nM	PMID[488371]
NPT2045	Cell Line	ETK-1	Homo sapiens	IC50	=	9751.45	nM	PMID[488371]
NPT2047	Cell Line	HC-1	Homo sapiens	IC50	=	5397.78	nM	PMID[488371]
NPT4609	Cell Line	HCC1143	Homo sapiens	IC50	=	7143.56	nM	PMID[488371]
NPT2394	Cell Line	HSC-4	Homo sapiens	IC50	=	11117.4	nM	PMID[488371]
NPT2049	Cell Line	HT	Homo sapiens	IC50	=	5512.58	nM	PMID[488371]
NPT2050	Cell Line	K052	Homo sapiens	IC50	=	29047.05	nM	PMID[488371]
NPT2051	Cell Line	K5	Homo sapiens	IC50	=	118590.22	nM	PMID[488371]
NPT2396	Cell Line	KYSE-510	Homo sapiens	IC50	=	5809.49	nM	PMID[488371]
NPT2397	Cell Line	KYSE-520 cell line		IC50	=	18453.61	nM	PMID[488371]
NPT2053	Cell Line	LU-139	Homo sapiens	IC50	=	1863763.3	nM	PMID[488371]
NPT2054	Cell Line	LU-165	Homo sapiens	IC50	=	105240.69	nM	PMID[488371]
NPT2055	Cell Line	ML-2	Homo sapiens	IC50	=	12433.87	nM	PMID[488371]
NPT2057	Cell Line	NCI-H1155	Homo sapiens	IC50	=	114485.02	nM	PMID[488371]
NPT2059	Cell Line	NCI-H2141	Homo sapiens	IC50	=	26779.03	nM	PMID[488371]
NPT2399	Cell Line	NCI-H2170	Homo sapiens	IC50	=	12109.42	nM	PMID[488371]
NPT2039	Cell Line	NCI-H82	Homo sapiens	IC50	=	49567.04	nM	PMID[488371]
NPT4610	Cell Line	NCI-H838	Homo sapiens	IC50	=	65824.1	nM	PMID[488371]
NPT2061	Cell Line	NCI-H889	Homo sapiens	IC50	=	9414242.68	nM	PMID[488371]
NPT2401	Cell Line	PANC-03-27	Homo sapiens	IC50	=	35085.29	nM	PMID[488371]
NPT2402	Cell Line	PANC-08-13	Homo sapiens	IC50	=	691456.33	nM	PMID[488371]
NPT2042	Cell Line	SBC-1	Homo sapiens	IC50	=	28484.58	nM	PMID[488371]
NPT2403	Cell Line	SBC-5	Homo sapiens	IC50	=	121751.73	nM	PMID[488371]
NPT146	Cell Line	SK-OV-3	Homo sapiens	IC50	=	10850.56	nM	PMID[488371]
NPT2063	Cell Line	SK-PN-DW	Homo sapiens	IC50	=	30632.67	nM	PMID[488371]
NPT2404	Cell Line	SW982	Homo sapiens	IC50	=	7338.91	nM	PMID[488371]
NPT2405	Cell Line	SAOS-2	Homo sapiens	IC50	=	3945.27	nM	PMID[488371]
NPT2245	Cell Line	SiHa	Homo sapiens	IC50	=	81236.04	nM	PMID[488371]
NPT403	Cell Line	UACC-257	Homo sapiens	IC50	=	43210.05	nM	PMID[488371]
NPT398	Cell Line	UACC-62	Homo sapiens	IC50	=	1747.7	nM	PMID[488371]
NPT2046	Cell Line	EVSA-T	Homo sapiens	IC50	=	138941.64	nM	PMID[488371]
NPT2065	Cell Line	EW-1	Homo sapiens	IC50	=	28567.22	nM	PMID[488371]
NPT2048	Cell Line	HCC1187	Homo sapiens	IC50	=	57830.83	nM	PMID[488371]
NPT2406	Cell Line	HCC1395	Homo sapiens	IC50	=	33262.94	nM	PMID[488371]
NPT2407	Cell Line	HCC1419	Homo sapiens	IC50	=	41799.02	nM	PMID[488371]
NPT453	Cell Line	HT-1080	Homo sapiens	IC50	=	4759.95	nM	PMID[488371]
NPT658	Cell Line	HT1197	Homo sapiens	IC50	=	25305.71	nM	PMID[488371]
NPT2419	Cell Line	HT-1376	Homo sapiens	IC50	=	5899.3	nM	PMID[488371]
NPT2052	Cell Line	KALS-1	Homo sapiens	IC50	=	14921.26	nM	PMID[488371]
NPT2067	Cell Line	KARPAS-299	Homo sapiens	IC50	=	548679.24	nM	PMID[488371]
NPT2408	Cell Line	KYSE-70 cell line		IC50	=	15148.8	nM	PMID[488371]
NPT2068	Cell Line	L-363	Homo sapiens	IC50	=	24117.6	nM	PMID[488371]
NPT2069	Cell Line	Lu-65	Homo sapiens	IC50	=	63421.06	nM	PMID[488371]
NPT2409	Cell Line	LU-99A	Homo sapiens	IC50	=	41511.4	nM	PMID[488371]
NPT2056	Cell Line	MLMA	Homo sapiens	IC50	=	50269.37	nM	PMID[488371]
NPT2071	Cell Line	MMAC-SF	Homo sapiens	IC50	=	26826.95	nM	PMID[488371]
NPT2410	Cell Line	NCI-H1299	Homo sapiens	IC50	=	66456.53	nM	PMID[488371]
NPT2073	Cell Line	NCI-H1304	Homo sapiens	IC50	=	34574.76	nM	PMID[488371]
NPT2060	Cell Line	NCI-H2171	Homo sapiens	IC50	=	201008.26	nM	PMID[488371]
NPT2075	Cell Line	NCI-H2196	Homo sapiens	IC50	=	275237.95	nM	PMID[488371]
NPT2076	Cell Line	NCI-H2227	Homo sapiens	IC50	=	3697806.19	nM	PMID[488371]
NPT2411	Cell Line	NCI-H2228	Homo sapiens	IC50	=	60021.99	nM	PMID[488371]
NPT465	Cell Line	NCI-N87	Homo sapiens	IC50	=	44810.43	nM	PMID[488371]
NPT788	Cell Line	SNU1	Homo sapiens	IC50	=	40375.53	nM	PMID[488371]
NPT2412	Cell Line	Panc1005	Homo sapiens	IC50	=	280689.76	nM	PMID[488371]
NPT2413	Cell Line	PC-14	Homo sapiens	IC50	=	15584.86	nM	PMID[488371]
NPT2062	Cell Line	SCC-15	Homo sapiens	IC50	=	7809.69	nM	PMID[488371]
NPT2414	Cell Line	SCC-25	Homo sapiens	IC50	=	57401.53	nM	PMID[488371]
NPT2078	Cell Line	SK-UT-1	Homo sapiens	IC50	=	4694.99	nM	PMID[488371]
NPT2415	Cell Line	SKG-IIIa	Homo sapiens	IC50	=	45363.55	nM	PMID[488371]
NPT550	Cell Line	T-24	Homo sapiens	IC50	=	158483.26	nM	PMID[488371]
NPT396	Cell Line	T47D	Homo sapiens	IC50	=	482990.51	nM	PMID[488371]
NPT2064	Cell Line	UACC-812	Homo sapiens	IC50	=	39209.38	nM	PMID[488371]
NPT2416	Cell Line	UACC-893	Homo sapiens	IC50	=	21661.66	nM	PMID[488371]
NPT2417	Cell Line	UMUC3	Homo sapiens	IC50	=	10135.56	nM	PMID[488371]
NPT2066	Cell Line	EW-11	Homo sapiens	IC50	=	58457.91	nM	PMID[488371]
NPT2080	Cell Line	EW-13	Homo sapiens	IC50	=	9672.7	nM	PMID[488371]
NPT2418	Cell Line	HCC1569	Homo sapiens	IC50	=	10330.44	nM	PMID[488371]
NPT2081	Cell Line	HCC1599	Homo sapiens	IC50	=	9037.11	nM	PMID[488371]
NPT2082	Cell Line	HT-144	Homo sapiens	IC50	=	8741.54	nM	PMID[488371]
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	7519.77	nM	PMID[488371]
NPT2083	Cell Line	KARPAS-422	Homo sapiens	IC50	=	20712.99	nM	PMID[488371]
NPT2084	Cell Line	KARPAS-45	Homo sapiens	IC50	=	15616.44	nM	PMID[488371]
NPT2086	Cell Line	L-428	Homo sapiens	IC50	=	5392.02	nM	PMID[488371]
NPT2087	Cell Line	L-540	Homo sapiens	IC50	=	8421.42	nM	PMID[488371]
NPT2070	Cell Line	LXF-289 cell line		IC50	=	8997.12	nM	PMID[488371]
NPT114	Cell Line	LoVo	Homo sapiens	IC50	=	3868.91	nM	PMID[488371]
NPT2072	Cell Line	MN-60	Homo sapiens	IC50	=	38941.79	nM	PMID[488371]
NPT2074	Cell Line	NCI-H1355	Homo sapiens	IC50	=	10088.25	nM	PMID[488371]
NPT2089	Cell Line	NCI-H1395	Homo sapiens	IC50	=	336886.14	nM	PMID[488371]
NPT405	Cell Line	NCI-H226	Homo sapiens	IC50	=	17863.88	nM	PMID[488371]
NPT2090	Cell Line	SNU-16	Homo sapiens	IC50	=	7576070.95	nM	PMID[488371]
NPT2091	Cell Line	SNU-5	Homo sapiens	IC50	=	91874.54	nM	PMID[488371]
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	14805.49	nM	PMID[488371]
NPT2093	Cell Line	PF-382	Homo sapiens	IC50	=	6166.73	nM	PMID[488371]
NPT2421	Cell Line	PFSK-1	Homo sapiens	IC50	=	13991.37	nM	PMID[488371]
NPT2077	Cell Line	SCC-3	Homo sapiens	IC50	=	1370841.41	nM	PMID[488371]
NPT2422	Cell Line	SCC-4	Homo sapiens	IC50	=	17398.67	nM	PMID[488371]
NPT2423	Cell Line	SCC-9	Homo sapiens	IC50	=	80260.61	nM	PMID[488371]
NPT368	Cell Line	SN12C	Homo sapiens	IC50	=	26572.13	nM	PMID[488371]
NPT392	Cell Line	SNB-75	Homo sapiens	IC50	=	17397.94	nM	PMID[488371]
NPT2424	Cell Line	T84	Homo sapiens	IC50	=	9869.57	nM	PMID[488371]
NPT1125	Cell Line	T98G	Homo sapiens	IC50	=	19646.91	nM	PMID[488371]
NPT2425	Cell Line	UMC-11	Homo sapiens	IC50	=	55920.72	nM	PMID[488371]
NPT2096	Cell Line	VA-ES-BJ	Homo sapiens	IC50	=	10682.28	nM	PMID[488371]
NPT2097	Cell Line	EW-16	Homo sapiens	IC50	=	4272.77	nM	PMID[488371]
NPT2098	Cell Line	EW-18	Homo sapiens	IC50	=	10508.8	nM	PMID[488371]
NPT2426	Cell Line	HCC1806	Homo sapiens	IC50	=	36191.92	nM	PMID[488371]
NPT1884	Cell Line	HCC1937	Homo sapiens	IC50	=	8626.45	nM	PMID[488371]
NPT2427	Cell Line	HCC1954	Homo sapiens	IC50	=	11341.23	nM	PMID[488371]
NPT2428	Cell Line	HT-3	Homo sapiens	IC50	=	27599.56	nM	PMID[488371]
NPT2429	Cell Line	HT55	Homo sapiens	IC50	=	34002.91	nM	PMID[488371]
NPT2099	Cell Line	KE-37	Homo sapiens	IC50	=	3443.95	nM	PMID[488371]
NPT2100	Cell Line	KG-1		IC50	=	552055.18	nM	PMID[488371]
NPT1358	Cell Line	LAMA-84	Homo sapiens	IC50	=	18518.16	nM	PMID[488371]
NPT2101	Cell Line	LAN-6	Homo sapiens	IC50	=	74974.5	nM	PMID[488371]
NPT2430	Cell Line	M059J	Homo sapiens	IC50	=	13083.99	nM	PMID[488371]
NPT387	Cell Line	M14	Homo sapiens	IC50	=	11006.31	nM	PMID[488371]
NPT2088	Cell Line	MOLT-16	Homo sapiens	IC50	=	11916.85	nM	PMID[488371]
NPT112	Cell Line	MOLT-4	Homo sapiens	IC50	=	10617.92	nM	PMID[488371]
NPT2104	Cell Line	NCI-H1417	Homo sapiens	IC50	=	119144.73	nM	PMID[488371]
NPT2105	Cell Line	NCI-H1436	Homo sapiens	IC50	=	201292.08	nM	PMID[488371]
NPT2431	Cell Line	NCI-H1437	Homo sapiens	IC50	=	6271.43	nM	PMID[488371]
NPT370	Cell Line	NCI-H23	Homo sapiens	IC50	=	146930.84	nM	PMID[488371]
NPT2432	Cell Line	NCI-H2342	Homo sapiens	IC50	=	6985.62	nM	PMID[488371]
NPT2092	Cell Line	NEC8	Homo sapiens	IC50	=	6890.82	nM	PMID[488371]
NPT2106	Cell Line	NH-12	Homo sapiens	IC50	=	3881.47	nM	PMID[488371]
NPT4611	Cell Line	PLC-PRF-5	Homo sapiens	IC50	=	6925.73	nM	PMID[488371]
NPT2107	Cell Line	PSN1	Homo sapiens	IC50	=	5412.65	nM	PMID[488371]
NPT2109	Cell Line	SCH	Homo sapiens	IC50	=	48347.48	nM	PMID[488371]
NPT2110	Cell Line	SCLC-21H	Homo sapiens	IC50	=	237243.73	nM	PMID[488371]
NPT4612	Cell Line	SNG-M	Homo sapiens	IC50	=	7052.36	nM	PMID[488371]
NPT890	Cell Line	SNU-387	Homo sapiens	IC50	=	27223.08	nM	PMID[488371]
NPT2433	Cell Line	SNU-423	Homo sapiens	IC50	=	41252.92	nM	PMID[488371]
NPT2095	Cell Line	TALL-1	Homo sapiens	IC50	=	120262.4	nM	PMID[488371]
NPT2434	Cell Line	TCC-SUP	Homo sapiens	IC50	=	11551.02	nM	PMID[488371]
NPT2112	Cell Line	TE-1	Homo sapiens	IC50	=	21569.43	nM	PMID[488371]
NPT2435	Cell Line	VM-CUB-1	Homo sapiens	IC50	=	10797.01	nM	PMID[488371]
NPT2436	Cell Line	VMRC-RCZ	Homo sapiens	IC50	=	9469.41	nM	PMID[488371]
NPT1653	Cell Line	WM-115	Homo sapiens	IC50	=	13757.24	nM	PMID[488371]
NPT2113	Cell Line	EW-24	Homo sapiens	IC50	=	49693.64	nM	PMID[488371]
NPT2115	Cell Line	HCC2157	Homo sapiens	IC50	=	49265.84	nM	PMID[488371]
NPT2116	Cell Line	HCC2218	Homo sapiens	IC50	=	13032.37	nM	PMID[488371]
NPT2438	Cell Line	HTC-C3	Homo sapiens	IC50	=	12841.65	nM	PMID[488371]
NPT2117	Cell Line	HuTu80	Homo sapiens	IC50	=	2354.41	nM	PMID[488371]
NPT2118	Cell Line	KGN	Homo sapiens	IC50	=	3217.68	nM	PMID[488371]
NPT2120	Cell Line	LB1047-RCC	Homo sapiens	IC50	=	5803.12	nM	PMID[488371]
NPT2121	Cell Line	LB2241-RCC	Homo sapiens	IC50	=	44717.73	nM	PMID[488371]
NPT2102	Cell Line	MC-CAR	Homo sapiens	IC50	=	4578.47	nM	PMID[488371]
NPT2439	Cell Line	MC-IXC	Homo sapiens	IC50	=	5391.02	nM	PMID[488371]
NPT2122	Cell Line	MC116	Homo sapiens	IC50	=	2818.15	nM	PMID[488371]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	IC50	=	21780.48	nM	PMID[488371]
NPT2123	Cell Line	MPP-89	Homo sapiens	IC50	=	25116.42	nM	PMID[488371]
NPT2125	Cell Line	NCI-H1522	Homo sapiens	IC50	=	30634.51	nM	PMID[488371]
NPT2440	Cell Line	NCI-H1563	Homo sapiens	IC50	=	313043.45	nM	PMID[488371]
NPT2449	Cell Line	NCI-H1573	Homo sapiens	IC50	=	14178.86	nM	PMID[488371]
NPT2441	Cell Line	NCI-H2347	Homo sapiens	IC50	=	7482.31	nM	PMID[488371]
NPT2442	Cell Line	NCI-H2405	Homo sapiens	IC50	=	7995.01	nM	PMID[488371]
NPT2450	Cell Line	NCI-H2452	Homo sapiens	IC50	=	227084.68	nM	PMID[488371]
NPT2126	Cell Line	NKM-1	Homo sapiens	IC50	=	280526.73	nM	PMID[488371]
NPT2127	Cell Line	NMC-G1	Homo sapiens	IC50	=	6970.81	nM	PMID[488371]
NPT2108	Cell Line	QIMR-WIL	Homo sapiens	IC50	=	5292.73	nM	PMID[488371]
NPT2128	Cell Line	RCC10RGB	Homo sapiens	IC50	=	109366.1	nM	PMID[488371]
NPT2111	Cell Line	SF-126	Homo sapiens	IC50	=	10326.73	nM	PMID[488371]
NPT395	Cell Line	SF-268	Homo sapiens	IC50	=	7896.63	nM	PMID[488371]
NPT2443	Cell Line	SNU-449	Homo sapiens	IC50	=	16490.84	nM	PMID[488371]
NPT4613	Cell Line	SNU-475	Homo sapiens	IC50	=	568004.87	nM	PMID[488371]
NPT2129	Cell Line	SNU-C1	Homo sapiens	IC50	=	10296.45	nM	PMID[488371]
NPT2130	Cell Line	TE-10	Homo sapiens	IC50	=	13314.22	nM	PMID[488371]
NPT2131	Cell Line	WSU-NHL	Homo sapiens	IC50	=	13624.45	nM	PMID[488371]
NPT2444	Cell Line	YAPC	Homo sapiens	IC50	=	464264.76	nM	PMID[488371]
NPT2114	Cell Line	EW-3	Homo sapiens	IC50	=	56016.48	nM	PMID[488371]
NPT4614	Cell Line	EW-7	Homo sapiens	IC50	=	23177.25	nM	PMID[488371]
NPT2132	Cell Line	EOL1	Homo sapiens	IC50	=	6729.5	nM	PMID[488371]
NPT391	Cell Line	HCC 2998	Homo sapiens	IC50	=	6802.89	nM	PMID[488371]
NPT2446	Cell Line	HCC38	Homo sapiens	IC50	=	17898.66	nM	PMID[488371]
NPT402	Cell Line	Hs-578T	Homo sapiens	IC50	=	11144.74	nM	PMID[488371]
NPT2447	Cell Line	HuCCT-1	Homo sapiens	IC50	=	9920.74	nM	PMID[488371]
NPT1229	Cell Line	Huh-7	Homo sapiens	IC50	=	241848.86	nM	PMID[488371]
NPT2119	Cell Line	KINGS-1	Homo sapiens	IC50	=	153978.04	nM	PMID[488371]
NPT2448	Cell Line	KLE	Homo sapiens	IC50	=	24012.75	nM	PMID[488371]
NPT2134	Cell Line	LB2518-MEL	Homo sapiens	IC50	=	88498.27	nM	PMID[488371]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	8346.36	nM	PMID[488371]
NPT2136	Cell Line	MDA-MB-134-VI	Homo sapiens	IC50	=	46436.05	nM	PMID[488371]
NPT2463	Cell Line	MDA-MB-157	Homo sapiens	IC50	=	6881.91	nM	PMID[488371]
NPT2124	Cell Line	MRK-nu-1	Homo sapiens	IC50	=	12905.98	nM	PMID[488371]
NPT2137	Cell Line	MS-1	Homo sapiens	IC50	=	38882.76	nM	PMID[488371]
NPT2138	Cell Line	MSTO-211H	Homo sapiens	IC50	=	82174.91	nM	PMID[488371]
NPT2139	Cell Line	NCI-H1581	Homo sapiens	IC50	=	37706.67	nM	PMID[488371]
NPT4615	Cell Line	NCI-H1618	Homo sapiens	IC50	=	2427334.45	nM	PMID[488371]
NPT2451	Cell Line	NCI-H28	Homo sapiens	IC50	=	26012.65	nM	PMID[488371]
NPT2452	Cell Line	NCI-H292		IC50	=	29367.8	nM	PMID[488371]
NPT2140	Cell Line	NOMO-1	Homo sapiens	IC50	=	12348.47	nM	PMID[488371]
NPT2141	Cell Line	NOS-1	Homo sapiens	IC50	=	4672.48	nM	PMID[488371]
NPT2453	Cell Line	RCM-1	Homo sapiens	IC50	=	22400.78	nM	PMID[488371]
NPT2454	Cell Line	RD	Homo sapiens	IC50	=	15302.68	nM	PMID[488371]
NPT399	Cell Line	SF-295	Homo sapiens	IC50	=	1754.75	nM	PMID[488371]
NPT374	Cell Line	SF-539	Homo sapiens	IC50	=	15448.53	nM	PMID[488371]
NPT2455	Cell Line	SNU-C2B	Homo sapiens	IC50	=	127629.18	nM	PMID[488371]
NPT385	Cell Line	SR	Homo sapiens	IC50	=	28178.83	nM	PMID[488371]
NPT2456	Cell Line	TE-11	Homo sapiens	IC50	=	47063.42	nM	PMID[488371]
NPT2144	Cell Line	TE-12	Homo sapiens	IC50	=	14374.59	nM	PMID[488371]
NPT2457	Cell Line	YKG-1	Homo sapiens	IC50	=	8875.06	nM	PMID[488371]
NPT2146	Cell Line	YT	Homo sapiens	IC50	=	12815.64	nM	PMID[488371]
NPT1216	Cell Line	FaDu	Homo sapiens	IC50	=	15778.69	nM	PMID[488371]
NPT2458	Cell Line	FTC-133	Homo sapiens	IC50	=	63252.52	nM	PMID[488371]
NPT2459	Cell Line	HCC70	Homo sapiens	IC50	=	212903.92	nM	PMID[488371]
NPT2460	Cell Line	HCE-4	Homo sapiens	IC50	=	8560.47	nM	PMID[488371]
NPT2461	Cell Line	HuO-3N1	Homo sapiens	IC50	=	702292.51	nM	PMID[488371]
NPT2133	Cell Line	KM-H2	Homo sapiens	IC50	=	26536.47	nM	PMID[488371]
NPT386	Cell Line	KM12	Homo sapiens	IC50	=	13484.04	nM	PMID[488371]
NPT2135	Cell Line	LB373-MEL-D	Homo sapiens	IC50	=	24203.37	nM	PMID[488371]
NPT2147	Cell Line	LB647-SCLC	Homo sapiens	IC50	=	188628.03	nM	PMID[488371]
NPT2148	Cell Line	LB771-HNC	Homo sapiens	IC50	=	65418.62	nM	PMID[488371]
NPT2464	Cell Line	MDA-MB-175-VII	Homo sapiens	IC50	=	80511.01	nM	PMID[488371]
NPT82	Cell Line	MDA-MB-231	Homo sapiens	IC50	=	21822.01	nM	PMID[488371]
NPT1649	Cell Line	MV4-11	Homo sapiens	IC50	=	136078.1	nM	PMID[488371]
NPT2465	Cell Line	NCI-H1623	Homo sapiens	IC50	=	25407.13	nM	PMID[488371]
NPT2150	Cell Line	NCI-H1648	Homo sapiens	IC50	=	9299.48	nM	PMID[488371]
NPT388	Cell Line	NCI-H322M	Homo sapiens	IC50	=	5482184.87	nM	PMID[488371]
NPT2151	Cell Line	NCI-H345	Homo sapiens	IC50	=	534923.1	nM	PMID[488371]
NPT2466	Cell Line	NCI-H358	Homo sapiens	IC50	=	11136.19	nM	PMID[488371]
NPT2152	Cell Line	NTERA-2-cl-D1	Homo sapiens	IC50	=	1596.16	nM	PMID[488371]
NPT2477	Cell Line	NUGC-3	Homo sapiens	IC50	=	9184.5	nM	PMID[488371]
NPT2142	Cell Line	REH	Homo sapiens	IC50	=	8619.03	nM	PMID[488371]
NPT2467	Cell Line	RERF-LC-MS	Homo sapiens	IC50	=	30604.68	nM	PMID[488371]
NPT2153	Cell Line	RH-1	Homo sapiens	IC50	=	13255.08	nM	PMID[488371]
NPT2154	Cell Line	SH-4	Homo sapiens	IC50	=	24897.59	nM	PMID[488371]
NPT2155	Cell Line	SHP77	Homo sapiens	IC50	=	65309.34	nM	PMID[488371]
NPT2143	Cell Line	ST486	Homo sapiens	IC50	=	8301.83	nM	PMID[488371]
NPT2156	Cell Line	SU-DHL-1	Homo sapiens	IC50	=	84512.29	nM	PMID[488371]
NPT2157	Cell Line	SUP-T1	Homo sapiens	IC50	=	7324.77	nM	PMID[488371]
NPT2481	Cell Line	SW1088	Homo sapiens	IC50	=	16654.73	nM	PMID[488371]
NPT2145	Cell Line	TE-15	Homo sapiens	IC50	=	7244.51	nM	PMID[488371]
NPT2158	Cell Line	TE-441-T	Homo sapiens	IC50	=	64975.42	nM	PMID[488371]
NPT2159	Cell Line	TE-5	Homo sapiens	IC50	=	9418.93	nM	PMID[488371]
NPT2160	Cell Line	no-10	Homo sapiens	IC50	=	13888.55	nM	PMID[488371]
NPT2161	Cell Line	no-11	Homo sapiens	IC50	=	9879.39	nM	PMID[488371]
NPT2468	Cell Line	G-361	Homo sapiens	IC50	=	5897.66	nM	PMID[488371]
NPT2469	Cell Line	G-401	Homo sapiens	IC50	=	8316.86	nM	PMID[488371]
NPT2470	Cell Line	G-402	Homo sapiens	IC50	=	11300.62	nM	PMID[488371]
NPT2162	Cell Line	HCE-T	Homo sapiens	IC50	=	13058.08	nM	PMID[488371]
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	28518.47	nM	PMID[488371]
NPT2471	Cell Line	HuP-T3	Homo sapiens	IC50	=	461596.44	nM	PMID[488371]
NPT2472	Cell Line	HuP-T4	Homo sapiens	IC50	=	7558.98	nM	PMID[488371]
NPT2163	Cell Line	KMOE-2	Homo sapiens	IC50	=	24313.17	nM	PMID[488371]
NPT2164	Cell Line	KMS-12-PE	Homo sapiens	IC50	=	57938.61	nM	PMID[488371]
NPT2166	Cell Line	LB831-BLC	Homo sapiens	IC50	=	12552.25	nM	PMID[488371]
NPT2473	Cell Line	MDA-MB-361	Homo sapiens	IC50	=	19573.55	nM	PMID[488371]
NPT2474	Cell Line	MDA-MB-415	Homo sapiens	IC50	=	29966.95	nM	PMID[488371]
NPT2488	Cell Line	MDA-MB-453	Homo sapiens	IC50	=	1184145.86	nM	PMID[488371]
NPT2149	Cell Line	MZ1-PC	Homo sapiens	IC50	=	5713.38	nM	PMID[488371]
NPT2168	Cell Line	MZ2-MEL	Homo sapiens	IC50	=	6327.02	nM	PMID[488371]
NPT1820	Cell Line	NCI-H1650	Homo sapiens	IC50	=	20782.08	nM	PMID[488371]
NPT2475	Cell Line	NCI-H1651	Homo sapiens	IC50	=	5977.65	nM	PMID[488371]
NPT2476	Cell Line	NCI-H441	Homo sapiens	IC50	=	6005.62	nM	PMID[488371]
NPT937	Cell Line	NCI-H446	Homo sapiens	IC50	=	14316600.26	nM	PMID[488371]
NPT2478	Cell Line	NY	Homo sapiens	IC50	=	4795.62	nM	PMID[488371]
NPT2479	Cell Line	OAW-28	Homo sapiens	IC50	=	20041.48	nM	PMID[488371]
NPT2170	Cell Line	RKO	Homo sapiens	IC50	=	2006.78	nM	PMID[488371]
NPT2171	Cell Line	SIG-M5	Homo sapiens	IC50	=	1310.62	nM	PMID[488371]
NPT2172	Cell Line	SIMA	Homo sapiens	IC50	=	6372.89	nM	PMID[488371]
NPT2483	Cell Line	SW13	Homo sapiens	IC50	=	12557.21	nM	PMID[488371]
NPT2173	Cell Line	TE-6	Homo sapiens	IC50	=	24289.06	nM	PMID[488371]
NPT2175	Cell Line	GAK	Homo sapiens	IC50	=	11740.5	nM	PMID[488371]
NPT2484	Cell Line	GAMG	Homo sapiens	IC50	=	9090.1	nM	PMID[488371]
NPT148	Cell Line	HCT-15	Homo sapiens	IC50	=	9245.99	nM	PMID[488371]
NPT2176	Cell Line	HD-MY-Z	Homo sapiens	IC50	=	26920.42	nM	PMID[488371]
NPT2485	Cell Line	IA-LM	Homo sapiens	IC50	=	2226.52	nM	PMID[488371]
NPT2486	Cell Line	IGR-1	Homo sapiens	IC50	=	5383.63	nM	PMID[488371]
NPT458	Cell Line	IGROV-1	Homo sapiens	IC50	=	5639.77	nM	PMID[488371]
NPT2165	Cell Line	KNS-42	Homo sapiens	IC50	=	36158.64	nM	PMID[488371]
NPT2178	Cell Line	KNS-81-FD	Homo sapiens	IC50	=	19529.05	nM	PMID[488371]
NPT2167	Cell Line	LB996-RCC	Homo sapiens	IC50	=	14122.54	nM	PMID[488371]
NPT2179	Cell Line	LC-1F	Homo sapiens	IC50	=	31225.94	nM	PMID[488371]
NPT2180	Cell Line	LC-2-ad	Homo sapiens	IC50	=	12949.96	nM	PMID[488371]
NPT784	Cell Line	MDA-MB-468	Homo sapiens	IC50	=	79690.87	nM	PMID[488371]
NPT1773	Cell Line	ME-180	Homo sapiens	IC50	=	30570.61	nM	PMID[488371]
NPT2169	Cell Line	MZ7-mel	Homo sapiens	IC50	=	9777.24	nM	PMID[488371]
NPT2489	Cell Line	MeWo	Homo sapiens	IC50	=	15928.93	nM	PMID[488371]
NPT2491	Cell Line	NCI-H1693	Homo sapiens	IC50	=	464767.37	nM	PMID[488371]
NPT2183	Cell Line	NCI-H1694	Homo sapiens	IC50	=	85831.84	nM	PMID[488371]
NPT397	Cell Line	NCI-H460	Homo sapiens	IC50	=	6088.05	nM	PMID[488371]
NPT2184	Cell Line	NCI-H510A	Homo sapiens	IC50	=	1179175.8	nM	PMID[488371]
NPT2492	Cell Line	OAW-42	Homo sapiens	IC50	=	302433.98	nM	PMID[488371]
NPT2186	Cell Line	RL	Homo sapiens	IC50	=	346098.36	nM	PMID[488371]
NPT2494	Cell Line	RMG-I	Homo sapiens	IC50	=	9241.88	nM	PMID[488371]
NPT3467	Cell Line	SJRH30	Homo sapiens	IC50	=	7974.35	nM	PMID[488371]
NPT2188	Cell Line	SJSA-1	Homo sapiens	IC50	=	4266.46	nM	PMID[488371]
NPT4616	Cell Line	SK-CO-1	Homo sapiens	IC50	=	13591.94	nM	PMID[488371]
NPT2495	Cell Line	SW1417	Homo sapiens	IC50	=	66941.56	nM	PMID[488371]
NPT2496	Cell Line	SW1463	Homo sapiens	IC50	=	76547.92	nM	PMID[488371]
NPT1577	Cell Line	SW1573	Homo sapiens	IC50	=	67354.45	nM	PMID[488371]
NPT2174	Cell Line	TE-8	Homo sapiens	IC50	=	11029.96	nM	PMID[488371]
NPT2189	Cell Line	TE-9	Homo sapiens	IC50	=	8498.73	nM	PMID[488371]
NPT2190	Cell Line	GB-1	Homo sapiens	IC50	=	5234.1	nM	PMID[488371]
NPT2191	Cell Line	GCIY	Homo sapiens	IC50	=	10132.99	nM	PMID[488371]
NPT2177	Cell Line	HDLM-2	Homo sapiens	IC50	=	17193.85	nM	PMID[488371]
NPT2497	Cell Line	HEC-1	Homo sapiens	IC50	=	13042.56	nM	PMID[488371]
NPT2193	Cell Line	IM-9	Homo sapiens	IC50	=	197041.03	nM	PMID[488371]
NPT2194	Cell Line	IMR-5	Homo sapiens	IC50	=	41501.81	nM	PMID[488371]
NPT4617	Cell Line	IPC-298	Homo sapiens	IC50	=	13359.26	nM	PMID[488371]
NPT2498	Cell Line	KOSC-2	Homo sapiens	IC50	=	469459.95	nM	PMID[488371]
NPT2499	Cell Line	KP-4	Homo sapiens	IC50	=	105791.48	nM	PMID[488371]
NPT2195	Cell Line	LC4-1	Homo sapiens	IC50	=	66863.22	nM	PMID[488371]
NPT2500	Cell Line	LCLC-103H cell line		IC50	=	9061.1	nM	PMID[488371]
NPT2181	Cell Line	MEG-01	Homo sapiens	IC50	=	25476.0	nM	PMID[488371]
NPT2501	Cell Line	MEL-HO	Homo sapiens	IC50	=	5107.0	nM	PMID[488371]
NPT2502	Cell Line	MEL-JUSO	Homo sapiens	IC50	=	7854.48	nM	PMID[488371]
NPT623	Cell Line	NALM-6	Homo sapiens	IC50	=	9089.79	nM	PMID[488371]
NPT2503	Cell Line	NCI-H1703	Homo sapiens	IC50	=	19086.0	nM	PMID[488371]
NPT4618	Cell Line	NCI-H1734	Homo sapiens	IC50	=	14953.76	nM	PMID[488371]
NPT2504	Cell Line	NCI-H1755	Homo sapiens	IC50	=	77322.27	nM	PMID[488371]
NPT2505	Cell Line	NCI-H520		IC50	=	13200.28	nM	PMID[488371]
NPT455	Cell Line	NCI-H522	Homo sapiens	IC50	=	17666.99	nM	PMID[488371]
NPT2185	Cell Line	OCI-AML2	Homo sapiens	IC50	=	9254.56	nM	PMID[488371]
NPT2199	Cell Line	OCUB-M	Homo sapiens	IC50	=	5320.53	nM	PMID[488371]
NPT2506	Cell Line	RO82-W-1	Homo sapiens	IC50	=	52494.79	nM	PMID[488371]
NPT2507	Cell Line	RPMI-2650	Homo sapiens	IC50	=	7317.55	nM	PMID[488371]
NPT1086	Cell Line	SK-HEP1	Homo sapiens	IC50	=	9580.54	nM	PMID[488371]
NPT2201	Cell Line	SK-LMS-1	Homo sapiens	IC50	=	5642.74	nM	PMID[488371]
NPT2508	Cell Line	SW1710	Homo sapiens	IC50	=	14105.23	nM	PMID[488371]
NPT2509	Cell Line	SW1783	Homo sapiens	IC50	=	10066.15	nM	PMID[488371]
NPT2202	Cell Line	TGBC1TKB	Homo sapiens	IC50	=	10976.11	nM	PMID[488371]
NPT2339	Cell Line	TGBC24TKB	Homo sapiens	IC50	=	26467.83	nM	PMID[488371]
NPT2510	Cell Line	GCT	Homo sapiens	IC50	=	352312.3	nM	PMID[488371]
NPT2203	Cell Line	GDM-1	Homo sapiens	IC50	=	28000.1	nM	PMID[488371]
NPT2192	Cell Line	HEL	Homo sapiens	IC50	=	11215.81	nM	PMID[488371]
NPT2511	Cell Line	HGC-27	Homo sapiens	IC50	=	7947.35	nM	PMID[488371]
NPT2205	Cell Line	IST-MEL1	Homo sapiens	IC50	=	7897.13	nM	PMID[488371]
NPT2206	Cell Line	IST-MES1	Homo sapiens	IC50	=	67497.19	nM	PMID[488371]
NPT2207	Cell Line	KP-N-YN	Homo sapiens	IC50	=	52749.8	nM	PMID[488371]
NPT2208	Cell Line	KP-N-YS	Homo sapiens	IC50	=	520596.88	nM	PMID[488371]
NPT2512	Cell Line	LCLC-97TM1	Homo sapiens	IC50	=	5962.49	nM	PMID[488371]
NPT2513	Cell Line	LK-2	Homo sapiens	IC50	=	17987.86	nM	PMID[488371]
NPT2514	Cell Line	LN-405	Homo sapiens	IC50	=	18842.24	nM	PMID[488371]
NPT2844	Cell Line	MES-SA	Homo sapiens	IC50	=	16517.41	nM	PMID[488371]
NPT2515	Cell Line	MFE-280	Homo sapiens	IC50	=	15671.82	nM	PMID[488371]
NPT3882	Cell Line	MFE-296	Homo sapiens	IC50	=	14427.47	nM	PMID[488371]
NPT2196	Cell Line	NB1	Homo sapiens	IC50	=	36967.2	nM	PMID[488371]
NPT2210	Cell Line	NB10	Homo sapiens	IC50	=	62332.32	nM	PMID[488371]
NPT2211	Cell Line	NB12	Homo sapiens	IC50	=	8231.94	nM	PMID[488371]
NPT2197	Cell Line	NCI-H1770	Homo sapiens	IC50	=	147982.05	nM	PMID[488371]
NPT1669	Cell Line	NCI-H1792	Homo sapiens	IC50	=	23131.7	nM	PMID[488371]
NPT2334	Cell Line	NCI-H1793	Homo sapiens	IC50	=	151568.85	nM	PMID[488371]
NPT444	Individual Protein	Ubiquitin carboxyl-terminal hydrolase 1	Homo sapiens	Potency	n.a.	35481.3	nM	PMID[488360]
NPT446	Individual Protein	Rap guanine nucleotide exchange factor 3	Homo sapiens	Potency	n.a.	112201.8	nM	PMID[488360]
NPT49	Individual Protein	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	Potency	n.a.	35481.3	nM	PMID[488359]
NPT446	Individual Protein	Rap guanine nucleotide exchange factor 3	Homo sapiens	Potency	n.a.	56234.1	nM	PMID[488360]
NPT570	Individual Protein	Arachidonate 5-lipoxygenase	Homo sapiens	IC50	=	1700.0	nM	PMID[488377]
NPT570	Individual Protein	Arachidonate 5-lipoxygenase	Homo sapiens	IC50	=	60.0	nM	PMID[488377]
NPT570	Individual Protein	Arachidonate 5-lipoxygenase	Homo sapiens	Ratio IC50	=	13.0	n.a.	PMID[488377]
NPT570	Individual Protein	Arachidonate 5-lipoxygenase	Homo sapiens	IC50	=	800.0	nM	PMID[488377]
NPT570	Individual Protein	Arachidonate 5-lipoxygenase	Homo sapiens	IC50	=	3500.0	nM	PMID[488377]
NPT3167	Individual Protein	Macrophage-expressed gene 1 protein	Homo sapiens	IC50	=	210.0	nM	PMID[488377]
NPT1119	Individual Protein	Arachidonate 12-lipoxygenase	Homo sapiens	Activity	=	74.9	%	PMID[488377]
NPT1079	Individual Protein	Histone acetyltransferase p300	Homo sapiens	Inhibition	=	75.0	%	PMID[488378]
NPT1080	Individual Protein	Histone acetyltransferase PCAF	Homo sapiens	IC50	=	7200.0	nM	PMID[488378]
NPT4248	Individual Protein	Histone acetyltransferase KAT5	Homo sapiens	Inhibition	=	75.0	%	PMID[488378]
NPT4309	Individual Protein	Inhibitor of apoptosis protein 3	Homo sapiens	IC50	=	4100.0	nM	PMID[488379]
NPT1385	Individual Protein	Histone-lysine N-methyltransferase SETD7	Homo sapiens	Inhibition	>	90.0	%	PMID[488388]
NPT2182	Cell Line	Mo	Homo sapiens	IC50	=	119830.11	nM	DOI[10.6019/CHEMBL1201861]
NPT35	Others	n.a.		LogP	=	5.04	n.a.	PMID[488356]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	39810.7	nM	PMID[488359]
NPT174	Organism	Streptococcus	Streptococcus	EC50	=	3319.0	nM	PMID[488360]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	39810.7	nM	PMID[488361]
NPT1252	Organism	Streptococcus sp. 'group A'	Streptococcus sp. 'group A'	EC50	=	1576.0	nM	PMID[488360]
NPT94	Individual Protein	Aldehyde dehydrogenase 1A1	Homo sapiens	Potency	=	39810.7	nM	PMID[488359]
NPT94	Individual Protein	Aldehyde dehydrogenase 1A1	Homo sapiens	Potency	=	19952.6	nM	PMID[488361]
NPT94	Individual Protein	Aldehyde dehydrogenase 1A1	Homo sapiens	Potency	=	23755.8	nM	PMID[488362]
NPT792	Individual Protein	Arachidonate 15-lipoxygenase	Homo sapiens	Potency	=	5011.9	nM	PMID[488361]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	7079.5	nM	PMID[488359]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	14125.4	nM	PMID[488361]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	31622.8	nM	PMID[488362]
NPT2	Others	Unspecified		Potency	=	15848.9	nM	PMID[488359]
NPT21702	PROTEIN-PROTEIN INTERACTION	Importin subunit beta-1/Snurportin-1	Homo sapiens	Potency	n.a.	125892.5	nM	PMID[488360]
NPT8	Individual Protein	DNA polymerase iota	Homo sapiens	Potency	n.a.	79432.8	nM	PMID[488360]
NPT803	Individual Protein	Flap endonuclease 1	Homo sapiens	Potency	n.a.	17782.8	nM	PMID[488360]
NPT8	Individual Protein	DNA polymerase iota	Homo sapiens	Potency	n.a.	100000.0	nM	PMID[488362]
NPT2	Others	Unspecified		EC50	=	5017.0	nM	PMID[488360]
NPT755	Individual Protein	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens	Potency	n.a.	28183.8	nM	PMID[488360]
NPT67	Individual Protein	Cholinesterase	Equus caballus	Inhibition	=	1.24	%	PMID[488367]
NPT489	Organism	Coptotermes formosanus	Coptotermes formosanus	Activity	=	10.7	mg	PMID[488369]
NPT489	Organism	Coptotermes formosanus	Coptotermes formosanus	mortality	=	46.7	%	PMID[488369]
NPT489	Organism	Coptotermes formosanus	Coptotermes formosanus	mortality	=	18.3	%	PMID[488369]
NPT489	Organism	Coptotermes formosanus	Coptotermes formosanus	mortality	=	3.3	%	PMID[488369]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	50.0	ug.mL-1	PMID[488370]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	15.0	ug.mL-1	PMID[488370]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	35.3	ug.mL-1	PMID[488370]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	49.0	ug.mL-1	PMID[488370]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	14.7	ug.mL-1	PMID[488370]
NPT73	Individual Protein	Solute carrier organic anion transporter family member 1B1	Homo sapiens	Inhibition	=	98.02	%	PMID[488372]
NPT72	Individual Protein	Solute carrier organic anion transporter family member 1B3	Homo sapiens	Inhibition	=	94.22	%	PMID[488372]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Potency	n.a.	23694.5	nM	PMID[488373]
NPT2	Others	Unspecified		Potency	n.a.	11220.2	nM	PMID[488360]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Potency	n.a.	21117.7	nM	PMID[488373]
NPT2	Others	Unspecified		Potency	n.a.	39810.7	nM	PMID[488374]
NPT2	Others	Unspecified		Potency	n.a.	28183.8	nM	PMID[488365]
NPT2	Others	Unspecified		Potency	n.a.	39810.7	nM	PMID[488360]
NPT831	Individual Protein	Serine/threonine-protein kinase PLK1	Homo sapiens	Potency	n.a.	29934.9	nM	PMID[488360]
NPT2	Others	Unspecified		Potency	n.a.	10000.0	nM	PMID[488362]
NPT2	Others	Unspecified		Potency	n.a.	15848.9	nM	PMID[488360]
NPT2	Others	Unspecified		IC50	=	4940.0	nM	PMID[488375]
NPT35	Others	n.a.		-log(solubility)	=	5.77	n.a.	PMID[488376]
NPT35	Others	n.a.		-log(solubility)	=	5.99	n.a.	PMID[488376]
NPT792	Individual Protein	Arachidonate 15-lipoxygenase	Homo sapiens	Activity	=	91.5	%	PMID[488377]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	795.0	nM	PMID[488379]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	Emax	=	86.0	%	PMID[488379]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	400.0	nM	PMID[488379]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	421.0	nM	PMID[488379]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	12300.0	nM	PMID[488379]
NPT956	Individual Protein	Prostaglandin E synthase	Homo sapiens	IC50	=	200.0	nM	PMID[488380]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	4.14	%	PMID[488382]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Hit score	=	0.1645	n.a.	PMID[488383]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	630.0	nM	PMID[488384]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	200.0	nM	PMID[488384]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	5000.0	nM	PMID[488384]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	421.0	nM	PMID[488384]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	EC50	=	89.0	nM	PMID[488384]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	Ki	=	23.6	nM	PMID[488384]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	Selectivity ratio	<=	803.0	n.a.	PMID[488384]
NPT23071	SINGLE PROTEIN	G-protein coupled receptor 84	Homo sapiens	Selectivity ratio	<=	57.0	n.a.	PMID[488384]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	16000.0	nM	PMID[488385]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	32000.0	nM	PMID[488385]
NPT20556	SINGLE PROTEIN	Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	14.16	%	PMID[488386]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	0.39	%	PMID[488387]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	IC50	>	20000.0	nM	PMID[488389]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	IC50	>	19952.62	nM	PMID[488389]

☑ Note for Activity Records:
☉ The quantitative biological activities were primarily integrated from ChEMBL (Version-30) database and were also directly collected from PubMed literature. PubMed PMID was provided as the reference link for each activity record.

Chemically structural similarity: I. Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes 4,3285 NPs with experimentally-derived bioactivity available in NPASS)

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

● The left chart: Distribution of similarity level between NPC143168 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	146
0.1-0.2	1974
0.2-0.3	10379
0.3-0.4	17527
0.4-0.5	7972
0.5-0.6	3875
0.6-0.7	719
0.7-0.8	77
0.8-0.85	8
0.85-0.9	6
0.9-0.95	9
0.95-1	5

Similarity Score	Similarity Level	Natural Product ID
1.0	High Similarity	NPC53109
0.9831	High Similarity	NPC7029
0.9661	High Similarity	NPC477830
0.9355	High Similarity	NPC243272
0.931	High Similarity	NPC320421
0.9206	High Similarity	NPC125578
0.9206	High Similarity	NPC146376
0.9206	High Similarity	NPC263382
0.9062	High Similarity	NPC94488
0.9062	High Similarity	NPC262673
0.8923	High Similarity	NPC94743
0.8923	High Similarity	NPC291062
0.8571	High Similarity	NPC474400
0.8571	High Similarity	NPC34622
0.8529	High Similarity	NPC264178
0.8462	Intermediate Similarity	NPC474619
0.8438	Intermediate Similarity	NPC98897
0.8413	Intermediate Similarity	NPC57463
0.8413	Intermediate Similarity	NPC151728
0.8413	Intermediate Similarity	NPC477707
0.8333	Intermediate Similarity	NPC134385
0.8308	Intermediate Similarity	NPC16119
0.8276	Intermediate Similarity	NPC137396
0.8028	Intermediate Similarity	NPC477708
0.7937	Intermediate Similarity	NPC473494
0.7917	Intermediate Similarity	NPC473536
0.7903	Intermediate Similarity	NPC192843
0.7733	Intermediate Similarity	NPC55869
0.7692	Intermediate Similarity	NPC40082
0.7681	Intermediate Similarity	NPC469914
0.7656	Intermediate Similarity	NPC274927
0.7656	Intermediate Similarity	NPC106851
0.7639	Intermediate Similarity	NPC175079
0.7619	Intermediate Similarity	NPC281230
0.76	Intermediate Similarity	NPC108955
0.7538	Intermediate Similarity	NPC122521
0.7538	Intermediate Similarity	NPC174447
0.7538	Intermediate Similarity	NPC235242
0.7538	Intermediate Similarity	NPC251042
0.7534	Intermediate Similarity	NPC110725
0.7532	Intermediate Similarity	NPC105803
0.75	Intermediate Similarity	NPC139056
0.7429	Intermediate Similarity	NPC474060
0.7424	Intermediate Similarity	NPC115752
0.7424	Intermediate Similarity	NPC15130
0.7424	Intermediate Similarity	NPC138056
0.7424	Intermediate Similarity	NPC473212
0.7424	Intermediate Similarity	NPC254449
0.7403	Intermediate Similarity	NPC103486
0.7391	Intermediate Similarity	NPC251429
0.7353	Intermediate Similarity	NPC61473
0.7342	Intermediate Similarity	NPC8518
0.7342	Intermediate Similarity	NPC263997
0.7342	Intermediate Similarity	NPC6185
0.7342	Intermediate Similarity	NPC474680
0.7342	Intermediate Similarity	NPC32037
0.7342	Intermediate Similarity	NPC132228
0.7342	Intermediate Similarity	NPC241512
0.7333	Intermediate Similarity	NPC30321
0.7333	Intermediate Similarity	NPC231739
0.7324	Intermediate Similarity	NPC173321
0.7313	Intermediate Similarity	NPC473210
0.7313	Intermediate Similarity	NPC473211
0.7297	Intermediate Similarity	NPC92080
0.7286	Intermediate Similarity	NPC477452
0.7273	Intermediate Similarity	NPC225515
0.7273	Intermediate Similarity	NPC275766
0.726	Intermediate Similarity	NPC147438
0.7246	Intermediate Similarity	NPC197089
0.7237	Intermediate Similarity	NPC27817
0.7213	Intermediate Similarity	NPC477458
0.72	Intermediate Similarity	NPC471061
0.7188	Intermediate Similarity	NPC477201
0.7143	Intermediate Similarity	NPC317796
0.7125	Intermediate Similarity	NPC470177
0.7105	Intermediate Similarity	NPC74410
0.7105	Intermediate Similarity	NPC475994
0.7105	Intermediate Similarity	NPC478122
0.7105	Intermediate Similarity	NPC189485
0.7089	Intermediate Similarity	NPC477785
0.7089	Intermediate Similarity	NPC477786
0.7089	Intermediate Similarity	NPC477784
0.7077	Intermediate Similarity	NPC200831
0.7077	Intermediate Similarity	NPC224103
0.7077	Intermediate Similarity	NPC299369
0.7067	Intermediate Similarity	NPC470525
0.7067	Intermediate Similarity	NPC1254
0.7067	Intermediate Similarity	NPC26504
0.7067	Intermediate Similarity	NPC180886
0.7042	Intermediate Similarity	NPC476614
0.7037	Intermediate Similarity	NPC203795
0.7037	Intermediate Similarity	NPC472009
0.7027	Intermediate Similarity	NPC122244
0.7013	Intermediate Similarity	NPC192329
0.7013	Intermediate Similarity	NPC475681
0.7	Intermediate Similarity	NPC137163
0.6986	Remote Similarity	NPC144627
0.6986	Remote Similarity	NPC84790
0.6984	Remote Similarity	NPC36061
0.6984	Remote Similarity	NPC294548
0.6984	Remote Similarity	NPC1813
0.6984	Remote Similarity	NPC139029
0.6984	Remote Similarity	NPC474805
0.6974	Remote Similarity	NPC211279
0.6974	Remote Similarity	NPC283087
0.697	Remote Similarity	NPC34416
0.6962	Remote Similarity	NPC47450
0.6957	Remote Similarity	NPC150162
0.6951	Remote Similarity	NPC472007
0.6949	Remote Similarity	NPC191337
0.6944	Remote Similarity	NPC67608
0.6944	Remote Similarity	NPC143396
0.6944	Remote Similarity	NPC10758
0.6944	Remote Similarity	NPC250928
0.6923	Remote Similarity	NPC325977
0.6914	Remote Similarity	NPC77971
0.6905	Remote Similarity	NPC475823
0.6905	Remote Similarity	NPC474209
0.6901	Remote Similarity	NPC473213
0.6892	Remote Similarity	NPC247586
0.6885	Remote Similarity	NPC145311
0.6883	Remote Similarity	NPC207772
0.6883	Remote Similarity	NPC248624
0.6883	Remote Similarity	NPC476808
0.6875	Remote Similarity	NPC25417
0.6875	Remote Similarity	NPC87564
0.6875	Remote Similarity	NPC258985
0.6875	Remote Similarity	NPC261831
0.6875	Remote Similarity	NPC53733
0.6875	Remote Similarity	NPC154245
0.6875	Remote Similarity	NPC87394
0.6875	Remote Similarity	NPC6095
0.6875	Remote Similarity	NPC88966
0.6875	Remote Similarity	NPC424
0.6875	Remote Similarity	NPC281972
0.6875	Remote Similarity	NPC32467
0.6875	Remote Similarity	NPC290563
0.6875	Remote Similarity	NPC85813
0.6867	Remote Similarity	NPC58271
0.6867	Remote Similarity	NPC53454
0.6867	Remote Similarity	NPC472008
0.6857	Remote Similarity	NPC474304
0.6857	Remote Similarity	NPC474329
0.6849	Remote Similarity	NPC318766
0.6849	Remote Similarity	NPC477455
0.6842	Remote Similarity	NPC186554
0.6842	Remote Similarity	NPC76966
0.6835	Remote Similarity	NPC472684
0.6835	Remote Similarity	NPC189237
0.6835	Remote Similarity	NPC474085
0.6835	Remote Similarity	NPC278459
0.6835	Remote Similarity	NPC99308
0.6835	Remote Similarity	NPC44963
0.6835	Remote Similarity	NPC116797
0.6825	Remote Similarity	NPC281245
0.6824	Remote Similarity	NPC45579
0.6818	Remote Similarity	NPC283502
0.6818	Remote Similarity	NPC268185
0.68	Remote Similarity	NPC227396
0.6786	Remote Similarity	NPC68148
0.6786	Remote Similarity	NPC112454
0.6786	Remote Similarity	NPC65615
0.6786	Remote Similarity	NPC474918
0.678	Remote Similarity	NPC25771
0.678	Remote Similarity	NPC477686
0.6774	Remote Similarity	NPC15325
0.6774	Remote Similarity	NPC474391
0.6765	Remote Similarity	NPC229252
0.6765	Remote Similarity	NPC143857
0.6765	Remote Similarity	NPC243532
0.6761	Remote Similarity	NPC100719
0.6761	Remote Similarity	NPC322035
0.6761	Remote Similarity	NPC166791
0.6761	Remote Similarity	NPC142423
0.6761	Remote Similarity	NPC308294
0.6757	Remote Similarity	NPC288667
0.6757	Remote Similarity	NPC474539
0.6753	Remote Similarity	NPC266124
0.6753	Remote Similarity	NPC97377
0.6753	Remote Similarity	NPC165711
0.6719	Remote Similarity	NPC321062
0.6719	Remote Similarity	NPC70387
0.6716	Remote Similarity	NPC281195
0.6714	Remote Similarity	NPC234767
0.6711	Remote Similarity	NPC251435
0.6711	Remote Similarity	NPC114236
0.6711	Remote Similarity	NPC474885
0.6709	Remote Similarity	NPC18955
0.6709	Remote Similarity	NPC2482
0.6709	Remote Similarity	NPC476809
0.6709	Remote Similarity	NPC74086
0.6707	Remote Similarity	NPC90287
0.6707	Remote Similarity	NPC255174
0.6707	Remote Similarity	NPC469993
0.6707	Remote Similarity	NPC33663
0.6707	Remote Similarity	NPC187529
0.6707	Remote Similarity	NPC79573
0.6706	Remote Similarity	NPC471399
0.6667	Remote Similarity	NPC298249
0.6667	Remote Similarity	NPC321180

Chemically structural similarity: II. Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC143168 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	136
0.1-0.2	2706
0.2-0.3	4152
0.3-0.4	1597
0.4-0.5	341
0.5-0.6	186
0.6-0.7	24
0.7-0.8	4
0.8-0.85	2
0.85-0.9	1
0.9-0.95	0
0.95-1	1

Similarity Score	Similarity Level	Drug ID	Developmental Stage
1.0	High Similarity	NPD2664	Clinical (unspecified phase)
0.8594	High Similarity	NPD3704	Approved
0.8308	Intermediate Similarity	NPD6108	Clinical (unspecified phase)
0.8169	Intermediate Similarity	NPD4756	Discovery
0.7838	Intermediate Similarity	NPD4695	Discontinued
0.7761	Intermediate Similarity	NPD7331	Phase 2
0.7353	Intermediate Similarity	NPD7341	Phase 2
0.7077	Intermediate Similarity	NPD8779	Phase 3
0.7031	Intermediate Similarity	NPD4627	Clinical (unspecified phase)
0.6984	Remote Similarity	NPD3172	Approved
0.6883	Remote Similarity	NPD3617	Approved
0.6875	Remote Similarity	NPD4266	Approved
0.6875	Remote Similarity	NPD3195	Phase 2
0.6875	Remote Similarity	NPD3196	Approved
0.6875	Remote Similarity	NPD3194	Approved
0.6786	Remote Similarity	NPD7285	Clinical (unspecified phase)
0.6714	Remote Similarity	NPD3197	Phase 1
0.6709	Remote Similarity	NPD8259	Clinical (unspecified phase)
0.6627	Remote Similarity	NPD5690	Phase 2
0.6585	Remote Similarity	NPD4197	Approved
0.6506	Remote Similarity	NPD5329	Approved
0.6429	Remote Similarity	NPD4694	Approved
0.6429	Remote Similarity	NPD5279	Phase 3
0.6429	Remote Similarity	NPD5280	Approved
0.6429	Remote Similarity	NPD3574	Clinical (unspecified phase)
0.6406	Remote Similarity	NPD28	Approved
0.6406	Remote Similarity	NPD29	Approved
0.6395	Remote Similarity	NPD4753	Phase 2
0.6349	Remote Similarity	NPD3173	Approved
0.6341	Remote Similarity	NPD4221	Approved
0.6341	Remote Similarity	NPD4800	Clinical (unspecified phase)
0.6341	Remote Similarity	NPD4223	Phase 3
0.631	Remote Similarity	NPD1696	Phase 3
0.6292	Remote Similarity	NPD5282	Discontinued
0.6222	Remote Similarity	NPD4629	Approved
0.6222	Remote Similarity	NPD5210	Approved
0.619	Remote Similarity	NPD3665	Phase 1
0.619	Remote Similarity	NPD3666	Approved
0.619	Remote Similarity	NPD3133	Approved
0.619	Remote Similarity	NPD622	Approved
0.6154	Remote Similarity	NPD5222	Approved
0.6154	Remote Similarity	NPD5220	Clinical (unspecified phase)
0.6154	Remote Similarity	NPD5221	Approved
0.6145	Remote Similarity	NPD3667	Approved
0.6118	Remote Similarity	NPD5363	Approved
0.6092	Remote Similarity	NPD4518	Approved
0.6087	Remote Similarity	NPD5173	Approved
0.6071	Remote Similarity	NPD6110	Phase 1
0.6047	Remote Similarity	NPD4138	Approved
0.6047	Remote Similarity	NPD4693	Phase 3
0.6047	Remote Similarity	NPD5205	Approved
0.6047	Remote Similarity	NPD3618	Phase 1
0.6047	Remote Similarity	NPD4689	Approved
0.6047	Remote Similarity	NPD4688	Approved
0.6047	Remote Similarity	NPD4623	Approved
0.6047	Remote Similarity	NPD4690	Approved
0.6047	Remote Similarity	NPD4519	Discontinued
0.6044	Remote Similarity	NPD5695	Phase 3
0.6	Remote Similarity	NPD5133	Approved
0.6	Remote Similarity	NPD4786	Approved
0.5978	Remote Similarity	NPD4697	Phase 3
0.5974	Remote Similarity	NPD4691	Approved
0.5957	Remote Similarity	NPD5285	Approved
0.5957	Remote Similarity	NPD5286	Approved
0.5957	Remote Similarity	NPD4696	Approved
0.5914	Remote Similarity	NPD4755	Approved
0.5914	Remote Similarity	NPD6084	Phase 2
0.5914	Remote Similarity	NPD6083	Phase 2
0.5909	Remote Similarity	NPD6672	Approved
0.5909	Remote Similarity	NPD5737	Approved
0.5895	Remote Similarity	NPD5223	Approved
0.5889	Remote Similarity	NPD6079	Approved
0.5889	Remote Similarity	NPD5281	Approved
0.5889	Remote Similarity	NPD5284	Approved
0.5889	Remote Similarity	NPD7515	Phase 2
0.5882	Remote Similarity	NPD7154	Phase 3
0.5873	Remote Similarity	NPD3174	Discontinued
0.5873	Remote Similarity	NPD4222	Approved
0.5851	Remote Similarity	NPD5696	Approved
0.5844	Remote Similarity	NPD4137	Phase 3
0.5843	Remote Similarity	NPD6080	Approved
0.5843	Remote Similarity	NPD6673	Approved
0.5843	Remote Similarity	NPD5328	Approved
0.5843	Remote Similarity	NPD6904	Approved
0.5833	Remote Similarity	NPD5226	Approved
0.5833	Remote Similarity	NPD5211	Phase 2
0.5833	Remote Similarity	NPD5225	Approved
0.5833	Remote Similarity	NPD5224	Approved
0.5833	Remote Similarity	NPD4633	Approved
0.5833	Remote Similarity	NPD5091	Approved
0.5833	Remote Similarity	NPD5369	Approved
0.5814	Remote Similarity	NPD3668	Phase 3
0.5806	Remote Similarity	NPD7614	Phase 1
0.5789	Remote Similarity	NPD4700	Approved
0.5783	Remote Similarity	NPD4195	Approved
0.5778	Remote Similarity	NPD46	Approved
0.5778	Remote Similarity	NPD5692	Phase 3
0.5778	Remote Similarity	NPD4096	Approved
0.5778	Remote Similarity	NPD6698	Approved
0.5778	Remote Similarity	NPD5785	Approved
0.5773	Remote Similarity	NPD5174	Approved
0.5773	Remote Similarity	NPD5175	Approved
0.5769	Remote Similarity	NPD4747	Approved
0.5765	Remote Similarity	NPD4269	Approved
0.5765	Remote Similarity	NPD4270	Approved
0.5761	Remote Similarity	NPD5122	Clinical (unspecified phase)
0.5761	Remote Similarity	NPD7748	Approved
0.575	Remote Similarity	NPD4058	Approved
0.5714	Remote Similarity	NPD6050	Approved
0.5714	Remote Similarity	NPD5694	Approved
0.5714	Remote Similarity	NPD4252	Approved
0.5714	Remote Similarity	NPD5141	Approved
0.5714	Remote Similarity	NPD5368	Approved
0.5714	Remote Similarity	NPD5693	Phase 1
0.5698	Remote Similarity	NPD5362	Discontinued
0.5696	Remote Similarity	NPD5276	Approved
0.5667	Remote Similarity	NPD6101	Approved
0.5667	Remote Similarity	NPD5783	Phase 3
0.5667	Remote Similarity	NPD5764	Clinical (unspecified phase)
0.5663	Remote Similarity	NPD5784	Clinical (unspecified phase)
0.5652	Remote Similarity	NPD6399	Phase 3
0.5652	Remote Similarity	NPD4202	Approved
0.5647	Remote Similarity	NPD4692	Approved
0.5647	Remote Similarity	NPD4139	Approved
0.5634	Remote Similarity	NPD9287	Clinical (unspecified phase)
0.5625	Remote Similarity	NPD39	Approved
0.5625	Remote Similarity	NPD9090	Phase 3
0.5618	Remote Similarity	NPD3573	Approved
0.5616	Remote Similarity	NPD4246	Clinical (unspecified phase)
0.5612	Remote Similarity	NPD4754	Approved
0.56	Remote Similarity	NPD5697	Approved

Bioactivity similarity: Similar Natural Products in NPASS

Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
☉ A: chemistry similarity;
☉ B: biological targets similarity;
☉ C: networks similarity;
☉ D: cell-based bioactivity similarity;
☉ E: similarity based on clinical data.

Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity

B: biological targets similarity

C: networks similarity

D: cell-based bioactivity similarity

E: similarity based on clinical data