Natural Product Target: Cytochrome P450 2C9

Target ID:   NPT212
Target Name:   Cytochrome P450 2C9
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ P11712]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC471614 Ketoconazole 10
NPC308885 Zucapsaicin 7
NPC208280 Glyburide 6
NPC469308 Sb-203580 6
NPC119818 (3R)-6,7-Dimethoxy-3-[(5R)-4-Methoxy-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-3H-2-Benzofuran-1-One 6
NPC70940 Dexibuprofen 5
NPC20791 Quercetin 5
NPC229113 Dicumarol 5
NPC149571 Raloxifene 5
NPC169749 Myricetin 5
NPC70290 1R,9S-Hydrastine 5
NPC473206 Diphenyleneiodonium 4
NPC248573 Cis-Resveratrol 4
NPC116775 Kaempferol 4
NPC116961 Loratadine 4
NPC190945 Nifedipine 4
NPC68441 Gossypol 4
NPC242895 Phloretin 3
NPC202771 Noscapine 3
NPC226941 Colchicine 3
NPC228343 Nordihydroguaiaretic Acid 3
NPC36836 Nicardipine 3
NPC78540 Chrysin 3
NPC42793 Verapamil 3
NPC471603 Sb-202190 3
NPC302950 Hesperetin 3
NPC218530 Dihydrocapsaicin 3
NPC129687 Asarinin 3
NPC195268 Papaverine 3
NPC476440 Tpck 2
NPC321053 Hydrochlorothiazide 2
NPC176814 Arctigenin 2
NPC33338 (1S)-1-Methyl-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol 2
NPC72788 (6S)-6-[(5R)-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-6H-Furo[3,4-G][1,3]Benzodioxol-8-One 2
NPC100079 Chelerythrine 2
NPC141791 2-Phenylethyl (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoate 2
NPC105488 Cycloserine 2
NPC328267 Fluoxetine 2
NPC254847 Emodin 2
NPC293454 Carnosic Acid 2
NPC228932 (2R)-2-Azaniumyl-3-Sulfosulfanylpropanoate 2
NPC148014 n.a. 2
NPC50898 Apigenin 2
NPC293799 Gs-39783 2
NPC208553 Paclitaxel 2
NPC115159 (Z)-1-(2,4-Dihydroxyphenyl)-3-(4-Hydroxyphenyl)Prop-2-En-1-One 2
NPC471615 Pleconaril 2
NPC476464 Chloroquine 2
NPC264166 Quinidine 2
NPC294909 Rauwolfia Serpentina 2
NPC316574 Mesalamine 2
NPC212415 Beta-Lapachone 2
NPC230805 8-Hydroxy-2-Methyl-1H-Quinazolin-4-One 2
NPC316896 Escitalopram 2
NPC231772 Acacetin 2
NPC316910 Celecoxib 2
NPC43945 Menadione 2
NPC51443 Fisetin 2
NPC234560 Daidzein 2
NPC470090 Sp-600125 2
NPC1075 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 2
NPC282294 Ethacrynic Acid 2
NPC193536 Spermidine 2
NPC93882 Nonivamide 2
NPC317567 Rifampicin 2
NPC215584 Elliptecine 2
NPC125416 Chlorhexidine 2
NPC46451 Sanguinarium 2
NPC282307 Pomiferin 2
NPC2989 Warfarin 2
NPC194857 4-Ethyl-3-Methyl-N-[2-[4-[(4-Methylcyclohexyl)Carbamoylsulfamoyl]Phenyl]Ethyl]-5-Oxo-2H-Pyrrole-1-Carboxamide 2
NPC318591 Propranolol 2
NPC471593 Sc-560 2
NPC58427 4-[(Z)-2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol 2
NPC320656 Sertraline 2
NPC220765 Serotonin 2
NPC13768 (R)-Pinocembrin 1
NPC171928 Sesamin 1
NPC291389 Harmol 1
NPC99734 Ethinyl Estradiol 1
NPC133771 (4R)-4-Hydroxy-4-Methyloxan-2-One 1
NPC245244 3-[(2R)-Piperidin-2-Yl]Pyridine 1
NPC314087 Adamantan-2-Ol 1
NPC205421 Isocorydine 1
NPC326248 N-Methylhistamine 1
NPC24019 Oxoglaucine 1
NPC227622 Erythromycin 1
NPC178134 Ellagic Acid 1
NPC292265 Ciprofloxacin 1
NPC73020 Hydrastine 1
NPC36491 Simvastatin 1
NPC207554 Tryptanthrin 1
NPC102008 Atorvastatin 1
NPC326651 (3R)-3-Hexadecanoyloxy-4-(Trimethylazaniumyl)Butanoate 1
NPC143168 Embelin 1
NPC471785 Sid11111800 1
NPC250266 2-(4-Hydroxyphenyl)-7-Methoxychromen-4-One 1
NPC178263 (1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Ol 1
NPC292998 7-Methoxy-2-Methyl-3-Phenylchromen-4-One 1
NPC74539 Bergapten 1
NPC108957 N-[(7R)-1,2,3,10-Tetramethoxy-9-Oxo-6,7-Dihydro-5H-Benzo[A]Heptalen-7-Yl]Acetamide 1
NPC41719 Karanjin 1
NPC228785 Mangostin 1
NPC147000 Pseudoephedrine 1
NPC66191 Dactinomycin 1
NPC20322 Aminopyrine 1
NPC76327 Acetaminophen 1
NPC37496 Glabranin 1
NPC21216 Estrone Sulfuric Acid 1
NPC109083 Curcumin 1
NPC329003 Oleoylethanolamide 1
NPC256849 Caffeine 1
NPC315403 Sulfanilamide 1
NPC329567 Levofloxacin 1
NPC229084 (1Z,6Z)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 1
NPC148231 Dibenzothiophene 1
NPC260977 Artemisinin 1
NPC185903 L-Carnosine 1
NPC294409 Biochanin 1
NPC78625 Ricinine 1
NPC315822 3-(4-Methoxyphenyl)-5-[[4-(4-Methoxyphenyl)-5-Methyl-1,2,4-Triazol-3-Yl]Sulfanylmethyl]-1,2,4-Oxadiazole 1
NPC209560 Formononetin 1
NPC116632 4',7-Dimethoxy-5-Hydroxygenistein 1
NPC149300 Tannic Acid 1
NPC187432 Galangin 1
NPC7491 n.a. 1
NPC473432 Amsacrine 1
NPC266597 Pratol 1
NPC190334 4-Amino-1-[(2R,3R,4S,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One 1
NPC298093 Rotenone 1
NPC7688 Silybin B 1
NPC212631 (E)-1-(2,6-Dihydroxy-4-Methoxyphenyl)-3-Phenylprop-2-En-1-One 1
NPC155444 Ergocryptine 1
NPC51146 Psoralen 1
NPC274455 Ibuprofen 1
NPC190461 n.a. 1
NPC85276 Deoxiepinephrine 1
NPC212794 Isoboldine 1
NPC231884 (S)-Verapamil 1
NPC161423 Testosterone 1
NPC278175 (Z)-1-[6-[(3-Acetyl-2,4,6-Trihydroxy-5-Methylphenyl)Methyl]-5,7-Dihydroxy-2,2-Dimethylchromen-8-Yl]-3-Phenylprop-2-En-1-One 1
NPC86452 n.a. 1
NPC39426 Genistein 1
NPC213216 5,7-Dihydroxy-2-(2-Hydroxyphenyl)Chromen-4-One 1
NPC120671 (6R)-6-[(5R)-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-6H-Furo[3,4-G][1,3]Benzodioxol-8-One 1
NPC476483 Vorinostat 1
NPC161571 Resveratrol 1
NPC52247 Hymecromone 1
NPC279121 Luteolin 1
NPC191104 Bergamottin 1
NPC92111 5-Meo-Dmt 1
NPC317400 Tolbutamide 1
NPC213308 2-(5-Hydroxy-1H-Indol-3-Yl)Acetic Acid 1
NPC125039 Silibinin 1
NPC235077 Triamcinolone 1
NPC164697 (-)-Usnic Acid 1
NPC236070 (2R)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-Trimethyltridecyl]-3,4-Dihydrochromen-6-Ol 1
NPC169089 n.a. 1
NPC3531 Valproic Acid 1
NPC95162 Fraxetin 1
NPC216361 Morin 1
NPC127447 Techtochrysin 1
NPC237946 Podofilox 1
NPC19174 Isoliquiritigenin 1
NPC283908 Pimaric Acid 1
NPC306843 Boldine 1
NPC194881 n.a. 1
NPC96286 Osthole 1
NPC320242 Metoprolol 1
NPC469812 Ivermectin 1
NPC239312 Baicalein 1
NPC66083 Haplamine 1
NPC32441 Naringenin 1
NPC307176 Progesterone 1
NPC10286 4-[(1R)-1-Hydroxy-2-(Methylamino)Ethyl]Phenol 1

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4. Species Source: species sources that all natural products that have available activity against this target derived from.

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