Unknown.
Italy; Algeria; Libya; France; Morocco; Spain
Ingredient ID: NPC90701
Ingredient ID: NPC87828
Ingredient ID: NPC86947
Ingredient ID: NPC85270
Ingredient ID: NPC76145
Ingredient ID: NPC75097
Ingredient ID: NPC66913
Ingredient ID: NPC63027
Ingredient ID: NPC62086
Ingredient ID: NPC52370
Ingredient ID: NPC49074
Ingredient ID: NPC482397
Ingredient ID: NPC482396
Ingredient ID: NPC482395
Ingredient ID: NPC482394
Ingredient ID: NPC482393
Ingredient ID: NPC482392
Ingredient ID: NPC482391
Ingredient ID: NPC482390
Ingredient ID: NPC482389
Ingredient ID: NPC482388
Ingredient ID: NPC476464
Ingredient ID: NPC41080
Ingredient ID: NPC39333
Ingredient ID: NPC36490
Ingredient ID: NPC36002
Ingredient ID: NPC35344
Ingredient ID: NPC299964
Ingredient ID: NPC288411
Ingredient ID: NPC278525
Ingredient ID: NPC264779
Ingredient ID: NPC259976
Ingredient ID: NPC248520
Ingredient ID: NPC248047
Ingredient ID: NPC243728
Ingredient ID: NPC242582
Ingredient ID: NPC241055
Ingredient ID: NPC232924
Ingredient ID: NPC230301
Ingredient ID: NPC226803
Ingredient ID: NPC22481
Ingredient ID: NPC223951
Ingredient ID: NPC221134
Ingredient ID: NPC218988
Ingredient ID: NPC216216
Ingredient ID: NPC214251
Ingredient ID: NPC211722
Ingredient ID: NPC211608
Ingredient ID: NPC211342
Ingredient ID: NPC209011
Ingredient ID: NPC198865
Ingredient ID: NPC194677
Ingredient ID: NPC190036
Ingredient ID: NPC189470
Ingredient ID: NPC186944
Ingredient ID: NPC185072
Ingredient ID: NPC184615
Ingredient ID: NPC179024
Ingredient ID: NPC177465
Ingredient ID: NPC176740
Ingredient ID: NPC175313
Ingredient ID: NPC168829
Ingredient ID: NPC168409
Ingredient ID: NPC168255
Ingredient ID: NPC166963
Ingredient ID: NPC154920
Ingredient ID: NPC149700
Ingredient ID: NPC142632
Ingredient ID: NPC141777
Ingredient ID: NPC141003
Ingredient ID: NPC138466
Ingredient ID: NPC13789
Ingredient ID: NPC128457
Ingredient ID: NPC122792
Ingredient ID: NPC117862
Ingredient ID: NPC116628
Ingredient ID: NPC115119
Ingredient ID: NPC114526
Ingredient ID: NPC114239
Ingredient ID: NPC113650
Ingredient ID: NPC11358
Ingredient ID: NPC112355
Ingredient ID: NPC105004
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
Therapeutic Target | Membrane receptor | SIGMAR1 | Sigma opioid receptor | Q99720 | CHEMBL287 |
Therapeutic Target | Metallo protease | MMP2 | Matrix metalloproteinase-2 | P08253 | CHEMBL333 |
Therapeutic Target | Small molecule receptor (family A GPCR) | CNR2 | Cannabinoid CB2 receptor | P34972 | CHEMBL253 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA1D | Alpha-1d adrenergic receptor | P25100 | CHEMBL223 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA1A | Alpha-1a adrenergic receptor | P35348 | CHEMBL229 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 87 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT01718054 | Vascular Function Intervention Trial in Sickle Cell Disease | sickle cell anemia | Chloroquine (NPC476464) | NP level |
NCT01546389 | Sanaria™ PfSPZ Challenge Vaccine | malaria | Chloroquine (NPC476464) | NP level |
NCT00521924 | Induction of Remission in RA Patients at Low Disease Activity by Additional Infliximab Therapy (Study P04644AM1) (TERMINATED) | rheumatoid arthritis | Chloroquine (NPC476464) | NP level |
NCT01500980 | Malaria Challenge in Healthy Volunteers | malaria | Chloroquine (NPC476464) | NP level |
NCT01640574 | Comparison Between 7 and 14 Day Primaquine Combined With Dihydroartemisinin-piperaquine or 3 Day Chloroquine Radical Cure of P. Vivax (BPD) | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT00282919 | A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT01103713 | Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa | pregnancy | Chloroquine (NPC476464) | NP level |
NCT00442403 | Safety and Efficacy of Chloroquine Associated With Dehydroepiandrosterone Sulphate to Treat Uncomplicated Falciparum Malaria | malaria | Chloroquine (NPC476464) | NP level |
NCT00082563 | Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT01290601 | Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults | malaria | Chloroquine (NPC476464) | NP level |
NCT03503058 | Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria | malaria | Chloroquine (NPC476464) | NP level |
NCT00811096 | Pilot Human Study of Tinidazole Efficacy For Radical Cure Of Plasmodium Vivax | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT04333628 | Chloroquine for Mild Symptomatic and Asymptomatic COVID-19 | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT01941095 | A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis | rheumatoid arthritis | Chloroquine (NPC476464) | NP level |
NCT04351295 | Efficacy of Faviprevir in COVID-19 Treatment | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT00131703 | Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women | pregnancy;malaria | Chloroquine (NPC476464) | NP level |
NCT04447534 | Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19 | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT01946880 | Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE) | systemic lupus erythematosus | Chloroquine (NPC476464) | NP level |
NCT02691910 | Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax Infection | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT01023477 | Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial) | breast ductal carcinoma in situ | Chloroquine (NPC476464) | NP level |
NCT04349371 | Saved From COVID-19 - Chloroquine (CQ) Prophylaxis for Health Care Workers at Risk for COVID | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT00084227 | Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT02511054 | Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B... | malaria | Chloroquine (NPC476464) | NP level |
NCT01376167 | Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT04420247 | Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19 | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT02432417 | The Addition of Chloroquine to Chemoradiation for Glioblastoma, | glioblastoma multiforme | Chloroquine (NPC476464) | NP level |
NCT04319900 | Clinical Trial of Favipiravir Tablets Combine With Chloroquine Phosphate in the Treatment of Novel Coronavirus Pneumonia | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT00074841 | Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT01205178 | G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine) | malaria | Chloroquine (NPC476464) | NP level |
NCT00677833 | Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT00118807 | Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children | malaria | Chloroquine (NPC476464) | NP level |
NCT02610686 | Evaluating the Efficacy of Chloroquine for the Treatment of Plasmodium Vivax Infections in Central Vietnam | malaria | Chloroquine (NPC476464) | NP level |
NCT00082576 | Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africa | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT00682578 | A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan | Plasmodium falciparum malaria;Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT02378532 | The Addition of Chloroquine to Chemoradiation for Glioblastoma | glioblastoma multiforme | Chloroquine (NPC476464) | NP level |
NCT00440999 | Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria | malaria | Chloroquine (NPC476464) | NP level |
NCT01074905 | Study on the Treatment of Vivax Malaria | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT04392622 | d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma | xerostomia | Limonene (NPC76145) | NP level |
NCT01894633 | Study of Whole-brain Irradiation With Chloroquine for Brain Metastases | brain disease | Chloroquine (NPC476464) | NP level |
NCT04303299 | Fight COVID-19 Trial | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT04360759 | Chloroquine Outpatient Treatment Evaluation for HIV-Covid-19 | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT01708876 | P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine | malaria | Chloroquine (NPC476464) | NP level |
NCT00158548 | ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan | Plasmodium falciparum malaria;Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT04351724 | Austrian CoronaVirus Adaptive Clinical Trial (COVID-19) | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT01814423 | Pharmacokinetic Study of Multi-dose Chloroquine | malaria | Chloroquine (NPC476464) | NP level |
NCT00819390 | Chloroquine for Reducing Immune Activation in HIV- Infected Individuals | HIV infection | Chloroquine (NPC476464) | NP level |
NCT02698748 | Evaluating the Role of Chloroquine for Malaria Elimination | malaria | Chloroquine (NPC476464) | NP level |
NCT03278808 | Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis | malaria | Chloroquine (NPC476464) | NP level |
NCT01575782 | Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer | small cell lung carcinoma | Chloroquine (NPC476464) | NP level |
NCT02773979 | PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT01777477 | Adjuvant Effect of Chloroquine on Gemcitabine | pancreatic carcinoma | Chloroquine (NPC476464) | NP level |
NCT01378286 | Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria | malaria | Chloroquine (NPC476464) | NP level |
NCT04853082 | Limonene on Regulating Metabolism-related Fatty Liver Disease (MAFLD) and Analysis of TCM Constitution | Hepatic steatosis | Limonene (NPC76145) | NP level |
NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients | prostate cancer | Rutin (NPC176740) | NP level |
NCT01100060 | A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects | malaria | Chloroquine (NPC476464) | NP level |
NCT00972725 | Evaluation of the Immune Response of a HIV Candidate Vaccine After Administration of One Chloroquine Dose | AIDS | Chloroquine (NPC476464) | NP level |
NCT00849602 | The Effect of Chloroquine in the Treatment of Patients With Dengue | Dengue Hemorrhagic Fever | Chloroquine (NPC476464) | NP level |
NCT04397679 | Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma | gliosarcoma | Chloroquine (NPC476464) | NP level |
NCT01103063 | Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa | pregnancy | Chloroquine (NPC476464) | NP level |
NCT00084240 | Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT02563496 | A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT01078779 | The Chloroquine for Influenza Prevention Trial | influenza | Chloroquine (NPC476464) | NP level |
NCT00323375 | Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With Chloroquine | malaria | Chloroquine (NPC476464) | NP level |
NCT02389374 | A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh | malaria | Chloroquine (NPC476464) | NP level |
NCT02996695 | Safety and Efficacy of Sanaria's PfSPZ-CVac in Malian Adults | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT02216123 | Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT02001012 | P. Knowlesi Trial of Artemether-lumefantrine vs Chloroquine | malaria | Chloroquine (NPC476464) | NP level |
NCT00969306 | Chloroquine as an Anti-Autophagy Drug in Stage IV Small Cell Lung Cancer (SCLC) Patients | small cell lung carcinoma | Chloroquine (NPC476464) | NP level |
NCT00871156 | Tafenoquine/Chloroquine DDI Study | malaria | Chloroquine (NPC476464) | NP level |
NCT02071537 | Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors | cancer | Chloroquine (NPC476464) | NP level |
NCT00486694 | Artesunate Plus Sulfadoxine-Pyrimethamine Versus Chloroquine for Vivax Malaria | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
NCT02333890 | A Phase 2 Randomized, Double-blind Trial Evaluating the Effects of Chloroquine in Breast Cancer | breast cancer | Chloroquine (NPC476464) | NP level |
NCT04345406 | Angiotensin Converting Enzyme Inhibitors in Treatment of Covid 19 | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT00844207 | A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine | malaria | Chloroquine (NPC476464) | NP level |
NCT04368910 | Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria | malaria | Chloroquine (NPC476464) | NP level |
NCT00224978 | Chloroquine for Treatment of Glioblastoma Multiforme | glioblastoma multiforme | Chloroquine (NPC476464) | NP level |
NCT00367653 | Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria. | malaria | Chloroquine (NPC476464) | NP level |
NCT04353336 | Efficacay of Chloroquine or Hydroxychloroquine in COVID-19 Treatment | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT00290420 | Prevention of P. Vivax Malaria During Pregnancy in Bolivia | malaria | Chloroquine (NPC476464) | NP level |
NCT01443130 | Chloroquine for Malaria in Pregnancy | malaria | Chloroquine (NPC476464) | NP level |
NCT01292408 | Autophagy Inhibition Using Hydrochloroquine in Breast Cancer Patients | breast cancer | Chloroquine (NPC476464) | NP level |
NCT01680406 | Ethiopia Antimalarial in Vivo Efficacy Study 2012 | malaria | Chloroquine (NPC476464) | NP level |
NCT01438177 | Chloroquine in Combination With VELCADE and Cyclophosphamide for Relapsed and Refractory Multiple Myeloma | multiple myeloma | Chloroquine (NPC476464) | NP level |
NCT00959517 | Trial of Artesunate Combination Therapy in Pakistan | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT00379821 | Chloroquine Alone or in Combination for Malaria in Children in Malawi | Plasmodium falciparum malaria | Chloroquine (NPC476464) | NP level |
NCT04627467 | Prevention With Chloroquine in Health Personnel Exposed to Infection With Coronavirus Disease 2019 (COVID-19) (TS-COVID) | COVID-19 | Chloroquine (NPC476464) | NP level |
NCT02348788 | Artemether-lumefantrine vs Chloroquine for Uncomplicated P. Vivax Malaria in Malaysia | Plasmodium vivax malaria | Chloroquine (NPC476464) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ADRA1D,CNR2,CNR1,SIGMAR1,ADRA1A,ACHE
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
ACHE,SIGMAR1,CNR1,MMP2,TMEM97,CNR2
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
NCT01443130,NCT00118807,NCT01708876,NCT00440999,NCT00323375,NCT04368910,NCT03278808,NCT02389374,NCT00844207,NCT00082563,NCT01100060,NCT00871156,NCT01814423,NCT00158548,NCT01205178,NCT00084240,NCT01290601,NCT01546389,NCT00367653,NCT00074841,NCT00677833,NCT00084227,NCT00959517,NCT02610686,NCT00082576,NCT00131703,NCT01680406,NCT00682578,NCT02698748,NCT02511054,NCT00282919,NCT03503058,NCT02001012,NCT00442403,NCT00379821,NCT00290420,NCT01500980,NCT02773979,NCT01378286,NCT02996695
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ACHE,CNR1,CNR1,F2
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
ACHE,CNR2,MMP2,F2
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
SIGMAR1,CNR1,TMEM97,CNR2
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ACHE,CNR1,CNR2,ADRA1D
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ACHE,MMP2,F2,CNR2
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
SIGMAR1,ADRA1A,ACHE
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
SIGMAR1,TMEM97,ACHE
|
Pregnancy/childbirth/puerperium maternal infectionDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JB63 |
NCT00131703,NCT01103713,NCT01103063
|
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT02378532,NCT02432417,NCT00224978
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
CNR1,MMP2,ADRA1D
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
SIGMAR1,TMEM97
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
ADRA1A,ADRA1D
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CNR1,CNR2
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
CNR2,CNR1
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
ADRA1A,ADRA1D
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ACHE,ADRA1D
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SIGMAR1,ACHE
|
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
ADRA1D,SIGMAR1
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
ADRA1A
NCT01705652 |
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
F2,CNR1
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ACHE
NCT01946880 |
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NCT01941095,NCT00521924
|
Small cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.1 |
NCT00969306,NCT01575782
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
NCT01292408,NCT02333890
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
CNR1,MMP2
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
CNR2,MMP2
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
CNR1,ADRA1D
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
ACHE,F2
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
ADRA1A,MMP2
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
ACHE,CNR2
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
TMEM97,CNR2
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
CNR2,CNR1
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04303299,NCT04360759,NCT04627467,NCT04351724,NCT04345406,NCT04351295,NCT04353336,NCT04349371,NCT04333628,NCT04420247,NCT04447534,NCT04319900
|
Malaria due to Plasmodium vivaxDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F41 |
NCT00682578,NCT02348788,NCT00486694,NCT02563496,NCT01640574,NCT00158548,NCT02691910,NCT02216123,NCT00811096,NCT01074905,NCT01376167
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Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
F2
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Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
CNR1
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Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Cannabis use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C41 |
CNR1
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CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
SIGMAR1
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PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Bulimia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B81 |
SIGMAR1
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Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
CNR1
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ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
CNR1
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Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
CNR1
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Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
MMP2
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CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
SIGMAR1
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Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
ADRA1D
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SomnolenceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG42 |
SIGMAR1
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Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F2
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Intellectual development disorderDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD90 |
SIGMAR1
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Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
CNR1
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Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
SIGMAR1
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Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F2
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Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
F2
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Immune system diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01-4B41 |
SIGMAR1
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DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
SIGMAR1
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Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
F2
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Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
SIGMAR1
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Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
F2
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Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
F2
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Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
SIGMAR1
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Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F2
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Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
F2
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Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
SIGMAR1
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Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
CNR2
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Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
SIGMAR1
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Epileptic encephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A62 |
SIGMAR1
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Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MMP2
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ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
F2
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Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
MMP2
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Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
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Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
CNR2
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Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
MMP2
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General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
CNR2
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Anorexia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B80 |
CNR1
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DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
ACHE
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Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
SIGMAR1
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Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
F2
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AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
F2
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Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
CNR1
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Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
CNR2
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Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
CNR1
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Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
MMP2
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Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
F2
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Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
ADRA1D
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Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
MMP2
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Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
CNR1
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Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
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Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
NCT01438177
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Dengue with warning signsDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D21 |
NCT00849602
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Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT01718054
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Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT01777477
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GliosarcomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH9RC8 |
NCT04397679
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Brain diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70-8E61 |
NCT01894633
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Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT02071537
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Other specified non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92.Y |
NCT04853082
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XerostomiaDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA02.1 |
NCT04392622
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InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
NCT01078779
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Congenital human immunodeficiency virus infectionDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA62.6 |
NCT00972725
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Ductal carcinoma in situ of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65.2 |
NCT01023477
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Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT00819390
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Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
TMEM97
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Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
SIGMAR1
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PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
ACHE
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Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE
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Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
MMP2
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Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
F2
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Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
F2
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Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
F2
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West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ACHE
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Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
F2
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Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
F2
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Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
ACHE
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Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ACHE
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Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
CNR1
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Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
F2
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Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
TMEM97
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Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CNR1
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Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
MMP2
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Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
ACHE
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Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
TMEM97
|