Plant ID: NPO5111
Plant Latin Name: Thalictrum Acutifolium
Taxonomy Genus: Thalictrum
Taxonomy Family: Ranunculaceae
NCBI TaxonomyDB:
1277762
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC8187
Ingredient ID: NPC66052
Ingredient ID: NPC309853
Ingredient ID: NPC293908
Ingredient ID: NPC28246
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 9 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT01528969 | Effect of Xylitol on Oral Microbiota in Children | bacterial disease | Sorbitol (NPC66052) | NP level |
NCT03747679 | Palatability (Taste) of Oral Formulations of Bosutinib | chronic myelogenous leukemia | Sorbitol (NPC66052) | NP level |
NCT04573153 | Metabolic Cofactor Supplementation and Hydroxychloroquine Combination in Covid-19 Patients | COVID-19 | Sorbitol (NPC66052) | NP level |
NCT04330326 | Metabolic Cofactor Supplementation in Obese Patients With Non-Alcoholic Fatty Liver Disease | non-alcoholic fatty liver disease | Sorbitol (NPC66052) | NP level |
NCT00374881 | A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human Subjects | pain | Sorbitol (NPC66052) | NP level |
NCT04762758 | Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients | Charcot-Marie-Tooth disease | Sorbitol (NPC66052) | NP level |
NCT03636971 | Gait Analysis Following Knee Viscosupplementation | osteoarthritis | Sorbitol (NPC66052) | NP level |
NCT05450458 | Hyaluronic Acid in Overuse Knee Pain | injury | Sorbitol (NPC66052) | NP level |
NCT01474499 | A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation | Constipation | Sorbitol (NPC66052) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
NCT04330326
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
NCT00374881
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT03636971
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04573153
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
NCT01528969
|
Chronic myeloid leukaemia, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4XG8 |
NCT03747679
|
ConstipationDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME05.0 |
NCT01474499
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
NCT05450458
|
Hereditary sensory or autonomic neuropathy, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C21.Z |
NCT04762758
|