Plant ID: NPO21040
Plant Latin Name: Ambrosia Artemisiifolia
Taxonomy Genus: Ambrosia
Taxonomy Family: Asteraceae
NCBI TaxonomyDB:
4212
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC97906
Ingredient ID: NPC97038
Ingredient ID: NPC95788
Ingredient ID: NPC94831
Ingredient ID: NPC94645
Ingredient ID: NPC94299
Ingredient ID: NPC93485
Ingredient ID: NPC91568
Ingredient ID: NPC88261
Ingredient ID: NPC8274
Ingredient ID: NPC82466
Ingredient ID: NPC80998
Ingredient ID: NPC79615
Ingredient ID: NPC78577
Ingredient ID: NPC76405
Ingredient ID: NPC73011
Ingredient ID: NPC69461
Ingredient ID: NPC68693
Ingredient ID: NPC54755
Ingredient ID: NPC479923
Ingredient ID: NPC479922
Ingredient ID: NPC479921
Ingredient ID: NPC479920
Ingredient ID: NPC479919
Ingredient ID: NPC479918
Ingredient ID: NPC479917
Ingredient ID: NPC46901
Ingredient ID: NPC43909
Ingredient ID: NPC43303
Ingredient ID: NPC3953
Ingredient ID: NPC3736
Ingredient ID: NPC312911
Ingredient ID: NPC312747
Ingredient ID: NPC312416
Ingredient ID: NPC311788
Ingredient ID: NPC310463
Ingredient ID: NPC307268
Ingredient ID: NPC305957
Ingredient ID: NPC29877
Ingredient ID: NPC294861
Ingredient ID: NPC293625
Ingredient ID: NPC289728
Ingredient ID: NPC287515
Ingredient ID: NPC277981
Ingredient ID: NPC273664
Ingredient ID: NPC27340
Ingredient ID: NPC269870
Ingredient ID: NPC265961
Ingredient ID: NPC263422
Ingredient ID: NPC255545
Ingredient ID: NPC253605
Ingredient ID: NPC252179
Ingredient ID: NPC251345
Ingredient ID: NPC2496
Ingredient ID: NPC242886
Ingredient ID: NPC242417
Ingredient ID: NPC227561
Ingredient ID: NPC223434
Ingredient ID: NPC221304
Ingredient ID: NPC221204
Ingredient ID: NPC208704
Ingredient ID: NPC207188
Ingredient ID: NPC205766
Ingredient ID: NPC20134
Ingredient ID: NPC190753
Ingredient ID: NPC187521
Ingredient ID: NPC18543
Ingredient ID: NPC184334
Ingredient ID: NPC182921
Ingredient ID: NPC180024
Ingredient ID: NPC171048
Ingredient ID: NPC164155
Ingredient ID: NPC163406
Ingredient ID: NPC155680
Ingredient ID: NPC154793
Ingredient ID: NPC153949
Ingredient ID: NPC153590
Ingredient ID: NPC148091
Ingredient ID: NPC14418
Ingredient ID: NPC136181
Ingredient ID: NPC131209
Ingredient ID: NPC130834
Ingredient ID: NPC124512
Ingredient ID: NPC12363
Ingredient ID: NPC122279
Ingredient ID: NPC118833
Ingredient ID: NPC110247
Ingredient ID: NPC108566
Ingredient ID: NPC10647
Ingredient ID: NPC105593
Ingredient ID: NPC104868
Ingredient ID: NPC100940
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 7 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT03597971 | HMPL004-6599 Phase I Dose-escalating Study | Crohn's disease;ulcerative colitis | Andrographolide (NPC124512) | NP level |
NCT01805791 | A Phase III Trial of HMPL-004 in Patients With Mild to Moderate Active Ulcerative Colitis | ulcerative colitis | Andrographolide (NPC124512) | NP level |
NCT02273635 | Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MS | primary progressive multiple sclerosis | Andrographolide (NPC124512) | NP level |
NCT00659802 | Phase II Study of HMPL-004 in Patients With Ulcerative Colitis | ulcerative colitis | Andrographolide (NPC124512) | NP level |
NCT00655733 | Phase II Study of HMPL-004 in Subjects With Crohn's Disease | Crohn's disease | Andrographolide (NPC124512) | NP level |
NCT01993472 | Study of Andrographolides With or Without Capecitabine to Treat Colorectal Cancer | colorectal neoplasm | Andrographolide (NPC124512) | NP level |
NCT01882764 | HMPL-004 Maintenance Treatment in Subjects With Mild to Moderate Ulcerative Colitis | ulcerative colitis | Andrographolide (NPC124512) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
NCT03597971,NCT00659802,NCT01805791,NCT01882764
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
NCT03597971,NCT00655733
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
NCT01993472
|
Primary progressive multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40.1 |
NCT02273635
|