Ingredient ID: NPC68873
Ingredient ID: NPC290598
Ingredient ID: NPC279884
Ingredient ID: NPC230726
Ingredient ID: NPC214289
Ingredient ID: NPC150560
Ingredient ID: NPC149209
Ingredient ID: NPC104195
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 2 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT05218850 | The Use of Butyrate Therapy in Pediatric Ulcerative Colitis | ulcerative colitis | Butanoic Acid (NPC149209) | NP level |
NCT01118663 | Safety and Efficacy Study of a New Formulation of Acetylcysteine Injection | drug-induced liver injury | Acetic Acid (NPC68873) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Drug-induced or toxic liver disease, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB95.Z |
NCT01118663
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
NCT05218850
|