Ingredient ID: NPC99179
Ingredient ID: NPC92213
Ingredient ID: NPC88097
Ingredient ID: NPC78990
Ingredient ID: NPC51141
Ingredient ID: NPC48887
Ingredient ID: NPC488041
Ingredient ID: NPC488040
Ingredient ID: NPC488039
Ingredient ID: NPC488038
Ingredient ID: NPC488037
Ingredient ID: NPC488036
Ingredient ID: NPC488035
Ingredient ID: NPC488034
Ingredient ID: NPC485314
Ingredient ID: NPC42793
Ingredient ID: NPC41122
Ingredient ID: NPC3990
Ingredient ID: NPC38749
Ingredient ID: NPC329307
Ingredient ID: NPC328155
Ingredient ID: NPC327549
Ingredient ID: NPC318805
Ingredient ID: NPC307789
Ingredient ID: NPC303519
Ingredient ID: NPC293624
Ingredient ID: NPC27405
Ingredient ID: NPC261384
Ingredient ID: NPC260015
Ingredient ID: NPC251580
Ingredient ID: NPC239584
Ingredient ID: NPC239282
Ingredient ID: NPC232489
Ingredient ID: NPC229317
Ingredient ID: NPC22849
Ingredient ID: NPC225774
Ingredient ID: NPC218761
Ingredient ID: NPC218652
Ingredient ID: NPC196231
Ingredient ID: NPC195538
Ingredient ID: NPC183485
Ingredient ID: NPC182767
Ingredient ID: NPC181964
Ingredient ID: NPC181796
Ingredient ID: NPC168384
Ingredient ID: NPC162026
Ingredient ID: NPC160842
Ingredient ID: NPC155350
Ingredient ID: NPC15237
Ingredient ID: NPC148597
Ingredient ID: NPC145304
Ingredient ID: NPC13565
Ingredient ID: NPC132842
Ingredient ID: NPC120414
Ingredient ID: NPC11999
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Peptide receptor (family A GPCR) | OPRK1 | Kappa opioid receptor | P41145 | CHEMBL237 |
Therapeutic Target | Peptide receptor (family A GPCR) | OPRD1 | Delta opioid receptor | P41143 | CHEMBL236 |
Therapeutic Target | Peptide receptor (family A GPCR) | CCKBR | Cholecystokinin B receptor | P32239 | CHEMBL298 |
Therapeutic Target | Peptide receptor (family A GPCR) | OPRM1 | Mu opioid receptor | P35372 | CHEMBL233 |
Drug Transporter | Potassium channels | KCNH2 | HERG | Q12809 | CHEMBL240 |
Drug Transporter | SLC superfamily of solute carriers | SLC6A4 | Serotonin transporter | P31645 | CHEMBL228 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HTR2C | Serotonin 2c (5-HT2c) receptor | P28335 | CHEMBL225 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HTR2A | Serotonin 2a (5-HT2a) receptor | P28223 | CHEMBL224 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD3 | Dopamine D3 receptor | P35462 | CHEMBL234 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HTR2B | Serotonin 2b (5-HT2b) receptor | P41595 | CHEMBL1833 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2A | Alpha-2a adrenergic receptor | P08913 | CHEMBL1867 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 23 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT01645709 | Safety, Tolerability, and Efficacy of IA Verapamil in the Treatment of Joint Pain in Subjects With Osteoarthritis of the Knee | osteoarthritis, knee | Verapamil (NPC42793) | NP level |
NCT02235558 | Superselective Administration of VErapamil During Recanalization in Acute Ischemic Stroke | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT00593463 | Drug Discrimination in Methadone-Maintained Humans Study 1 | drug dependence | Verapamil (NPC42793) | NP level |
NCT04351763 | Amiodarone or Verapamil in COVID-19 Hospitalized Patients With Symptoms | COVID-19 | Verapamil (NPC42793) | NP level |
NCT01607073 | Verapamil as Therapy for Children and Young Adults With Dravet Syndrome | Dravet syndrome | Verapamil (NPC42793) | NP level |
NCT04545151 | Verapamil SR in Adults With Type 1 Diabetes | type 1 diabetes mellitus | Verapamil (NPC42793) | NP level |
NCT00518947 | Pharmacotherapy of Treatment-Resistant Mania | bipolar disorder | Verapamil (NPC42793) | NP level |
NCT02823106 | Superselective Citicoline and Verapamil for Ischemic Neuroprotection and Greater Effective Response | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT00804895 | Cluster Headache Cortivazol Injection (CHCI) | pain | Verapamil (NPC42793) | NP level |
NCT03782662 | Drug Interaction Study With RV521 in Healthy Volunteer Subjects | Respiratory Syncytial Virus Infection | Verapamil (NPC42793) | NP level |
NCT03013933 | Brentuximab Vedotin, Cyclosporine, and Verapamil Hydrochloride in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma | Hodgkins lymphoma | Verapamil (NPC42793) | NP level |
NCT00000556 | Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) | atrial fibrillation | Verapamil (NPC42793) | NP level |
NCT02372253 | Verapamil for Beta Cell Survival Therapy in Type 1 Diabetes | type 1 diabetes mellitus | Verapamil (NPC42793) | NP level |
NCT03296800 | Study to Evaluate Effects of Probenecid, Rifampin and Verapamil on Bexagliflozin in Healthy Subjects | type 2 diabetes mellitus | Verapamil (NPC42793) | NP level |
NCT00589303 | AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study | atrial fibrillation;heart failure | Verapamil (NPC42793) | NP level |
NCT00313157 | RATe Control in Atrial Fibrillation | atrial fibrillation | Verapamil (NPC42793) | NP level |
NCT04233034 | Hybrid Closed Loop Therapy and Verapamil for Beta Cell Preservation in New Onset Type 1 Diabetes | type 1 diabetes mellitus | Verapamil (NPC42793) | NP level |
NCT04356196 | Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia. | hemorrhage | Verapamil (NPC42793) | NP level |
NCT03347786 | Verapamil for Neuroprotection in Stroke | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT01261286 | Drug-Disease Interaction in Crohn's Disease | Crohn's disease | Verapamil (NPC42793) | NP level |
NCT02772354 | Radiofrequency Ablation of Symptomatic Frequent Ventricular Premature Complexes in Pediatric Population | Ventricular arrhythmia | Verapamil (NPC42793) | NP level |
NCT02912663 | Magnesium And Verapamil After Recanalization in Ischemia of the Cerebrum: a Clinical and Translational Study. | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT02209155 | R-Verapamil for the Prophylaxis of Episodic Cluster Headache | pain | Verapamil (NPC42793) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
OPRK1,OPRD1,ADRA2A,KCNH2,HTR2C,OPRM1,SLC6A4
NCT02209155,NCT00804895 |
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
SLC6A4,ADRA2A,OPRK1,DRD3,HTR2B,HTR2C,HTR2A,OPRM1
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
OPRM1,OPRD1,CACNA1C,OPRK1,ADRA2A,CACNA1F,HTR2A
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
HTR2B,DRD3,HTR2C,SLC6A4,ADRA2A,HTR2A
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
OPRD1,CCKBR,OPRK1,HTR2C,KCNH2,CACNA1F
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
ABCG2,CACNA1C,HTR2B,KCNH2,ABCB1,HTR2A
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
OPRD1,CCKBR,ADRA2A,ABCB1,CACNA1F,HTR2A
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
OPRD1,OPRK1,HTR2B,HTR2C,KCNH2,ADRA2A
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
CACNA1C,HTR2A,SLC6A4,HTR2C,DRD3
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
SLC6A4,CCKBR,HTR2C,HTR2A,OPRD1
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
OPRK1,OPRD1,OPRM1,SLC6A4,HTR2A
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
HTR2C,OPRK1,SLC6A4,ADRA2A,OPRM1
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
OPRD1,CCKBR,OPRK1,HTR2C,SLC6A4
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
CACNA1C,KCNH2,ADRA2A,SLC6A4,CACNA1F
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
OPRD1,CACNA1C,CCKBR,KCNH2,SLC6A4
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
OPRD1,CCKBR,KCNH2,OPRD1,CACNA1F
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
OPRD1,CCKBR,HTR2C,KCNH2,SLC6A4
|
Opioid use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C43 |
OPRD1,OPRM1,ADRA2A,OPRK1
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
HTR2C,OPRM1,SLC6A4,OPRD1
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
OPRM1,OPRK1,ABCG2,OPRD1
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
HTR2A,DRD3,HTR2C,SLC6A4
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SLC6A4,HTR2C,HTR2A,DRD3
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
OPRK1,HTR2A,DRD3
NCT00518947 |
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
NCT02823106,NCT02235558,NCT03347786,NCT02912663
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
OPRK1,KCNH2,ABCB1,OPRD1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
OPRK1,HTR2C,KCNH2,HTR2A
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
OPRD1,ABCG2,CCKBR,HTR2C
|
Coronary vasospastic diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA85 |
OPRM1,OPRK1,OPRD1
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
SLC6A4,OPRM1,HTR2C
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
HTR2A,HTR2C,HTR2B
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
OPRD1,SLC6A4,OPRM1
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
ABCB1,CCKBR,DRD3
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
SLC6A4,CCKBR,OPRM1
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
HTR2A,HTR2C,HTR2B
|
Sleep-wake disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7B2Z |
HTR2A,KCNH2,HTR2C
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT02372253,NCT04233034,NCT04545151
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT00589303,NCT00313157,NCT00000556
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
ADRA2A,HTR2B,CACNA1C
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CCKBR,OPRK1,HTR2C
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
HTR2C,KCNH2,ABCG2
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
HTR2C,KCNH2,KCNH2
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
CCKBR,OPRK1,HTR2C
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
HTR2A,SLC6A4,ABCG2
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
OPRK1,KCNH2,SLC6A4
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
HTR2C,KCNH2,ADRA2A
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
HTR2A,SLC6A4
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
SLC6A4,HTR2A
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
SLC6A4,OPRM1
|
Binge eating disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B82 |
OPRM1,SLC6A4
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ABCG2,OPRD1
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
KCNH2
NCT00589303 |
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
HTR2A,DRD3
|
PruritusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EC90 |
OPRK1,OPRM1
|
Bowel habit changeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME05 |
OPRD1,OPRM1
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
HTR2A,HTR2C
|
Chronic insomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00 |
HTR2C,HTR2A
|
Spinal painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84 |
OPRD1,OPRM1
|
Psychoactive substances use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G |
HTR2C,DRD3
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
HTR2A
NCT03296800 |
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
DRD3,ABCG2
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
OPRD1,HTR2C
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
HTR2B,HTR2A
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
HTR2A
|
Acute painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG31 |
OPRM1
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
SLC6A4
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
HTR2A
|
Pancreatic malfunctionDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC30-DC3Z |
CCKBR
|
Tension-type headacheDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A81 |
OPRM1
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
OPRM1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
ABCB1
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
CCKBR
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
KCNH2
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
SLC6A4
|
PrurigoDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EC91 |
OPRK1
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
DRD3
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CCKBR
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
SLC6A4
|
Breathing abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11 |
OPRM1
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
DRD3
|
Digestive system diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DE2Z |
OPRM1
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
SLC6A4
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
DRD3
|
Skin sensation disturbanceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME65 |
OPRM1
|
Pancreatic internal secretion disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A4Y |
CCKBR
|
Diagnostic imagingDisease Category: NADisease ICD-11 Code: N.A. |
CCKBR
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
SLC6A4
|
concerning food/fluid intake symptomDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG43 |
SLC6A4
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
DRD3
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
HTR2A
|
Mental/behavioural/neurodevelopmental disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20-6E8Z |
OPRM1
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
HTR2A
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
DRD3
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
HTR2C
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
ABCB1
|
Functional bladder disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC50 |
OPRD1
|
Gastric ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA60 |
CCKBR
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
HTR2A
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
CCKBR
|
Social anxiety disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B04 |
HTR2A
|
Soft tissue disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB56 |
SLC6A4
|
Gastroduodenal motor/secretory disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41 |
DRD3
|
Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
SLC6A4
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
CCKBR
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
DRD3
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
HTR2A
|
Stomach diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA43-DA4Y |
CCKBR
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
HTR2B
|
Large intestine motility disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB32 |
OPRM1
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
HTR2A
|
Non-specific cutaneous vascular symptonDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME64 |
OPRK1
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
HTR2A
|
Acute upper respiratory infectionDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA07 |
DRD3
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
DRD3
|
Tonus and reflex abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB47 |
HTR2C
|
Ejaculatory dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA03 |
SLC6A4
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
KCNH2
|
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
HTR2A
|
Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G.2Z |
NCT00593463
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04351763
|
Pneumonia due to Respiratory syncytial virusDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.11 |
NCT03782662
|
Dravet syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61.11 |
NCT01607073
|
Ventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC71 |
NCT02772354
|
Osteoarthritis of kneeDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
NCT01645709
|
Hodgkin lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B30 |
NCT03013933
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Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
NCT01261286
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Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT04356196
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Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
HTR2A
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Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
HTR2C
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Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
HTR2C
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
ADRA2A
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Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
ABCG2
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
HTR2C
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Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
ADRA2A
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Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
HTR2C
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Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2
|