Plant ID: NPO10150
Plant Latin Name: Anemone Raddeana
Taxonomy Genus: Anemone
Taxonomy Family: Ranunculaceae
NCBI TaxonomyDB:
387928
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC96026
Ingredient ID: NPC95615
Ingredient ID: NPC84252
Ingredient ID: NPC60288
Ingredient ID: NPC47042
Ingredient ID: NPC36408
Ingredient ID: NPC294355
Ingredient ID: NPC281584
Ingredient ID: NPC274327
Ingredient ID: NPC269440
Ingredient ID: NPC268465
Ingredient ID: NPC266960
Ingredient ID: NPC264317
Ingredient ID: NPC255580
Ingredient ID: NPC245127
Ingredient ID: NPC242419
Ingredient ID: NPC231738
Ingredient ID: NPC201252
Ingredient ID: NPC194282
Ingredient ID: NPC188261
Ingredient ID: NPC18772
Ingredient ID: NPC182261
Ingredient ID: NPC178383
Ingredient ID: NPC167072
Ingredient ID: NPC165287
Ingredient ID: NPC163666
Ingredient ID: NPC152316
Ingredient ID: NPC146511
Ingredient ID: NPC123096
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Nuclear hormone receptor subfamily 1 | NR1H4 | Bile acid receptor FXR | Q96RI1 | CHEMBL2047 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 2 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00701987 | Safety, Tolerability, and Preliminary Efficacy Study of ALS-357 in Patients With Cutaneous Metastatic Melanoma | melanoma | Betulinic Acid (NPC264317) | NP level |
NCT00346502 | Evaluation of 20% Betulinic Acid Ointment for Treatment of Dysplastic Nevi (Moderate to Severe Dysplasia) | dysplastic nevus | Betulinic Acid (NPC264317) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NCT00701987
|
Dysplastic naevusDisease Category: X.Extension CodesDisease ICD-11 Code: XH9035 |
NCT00346502
|