Natural Product Target: DNA topoisomerase II

Target ID:   NPT320
Target Name:   DNA topoisomerase II
Target Type:   Protein Family
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ Q02880]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC185498 Etoposide 28
NPC473432 Amsacrine 10
NPC329567 Levofloxacin 4
NPC163527 (5Ar,8Ar,9R)-4-Hydroxy-9-(4-Hydroxy-3,5-Dimethoxyphenyl)-5A,6,8A,9-Tetrahydro-5H-[2]Benzofuro[5,6-F][1,3]Benzodioxol-8-One 2
NPC28657 Cholesterol 1
NPC257728 Novobiocin 1
NPC261012 Doxorubicin 1
NPC292265 Ciprofloxacin 1
NPC255909 Diplamine 1
NPC282793 n.a. 1
NPC157583 n.a. 1
NPC163867 n.a. 1
NPC71460 (3S,5S,10S,13R,17R)-17-((R)-1,5-Dimethyl-Hexyl)-10,13-Dimethyl-Hexadecahydro-Cyclopenta[A]Phenanthren-3-Ol 1
NPC77022 n.a. 1
NPC66699 Shermilamine B 1
NPC1203 Rebeccamycin 1
NPC173344 Kuanoniamine D 1
NPC472533 n.a. 1
NPC124636 n.a. 1
NPC469966 n.a. 1
NPC268170 Adociaquinone B 1
NPC237946 Podofilox 1

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4. Species Source: species sources that all natural products that have available activity against this target derived from.

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