Natural Product Target: Isocitrate lyase

Target ID:   NPT1087
Target Name:   Isocitrate lyase
Target Type:   Individual Protein
Organism of Target:   Candida albicans
Target External ID:   Uniprot_ID:[ Q9P8Q7]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC124886 n.a. 11
NPC220765 Serotonin 3
NPC276657 Hyrtiosin B 3
NPC219087 Hyrtiosin A 3
NPC171787 5-Hydroxyindole-3-Carbaldehyde 3
NPC276517 1-Carboxy-6-Hydroxy-3,4-Dihydro-Beta-Carboline 3
NPC325544 Halisulfate 1 2
NPC169098 Itaconate 2
NPC177962 2-(3,7-Dimethyl-9-((1S,4As,8As)-2,5,5,8A-Tetramethyl-1,4,4A,5,6,7,8,8A-Octahydronaphthalen-1-Yl)Nona-2,7-Dienyl)Benzene-1,4-Diol 2
NPC122599 Cadiolide E 2
NPC235033 Cadiolide G 2
NPC81137 Cadiolide I 2
NPC74360 Methyl 5-Hydroxy-1H-Indole-3-Carboxylate 2
NPC323074 Sodium (2R,3R)-9-(2,5-Dihydroxyphenyl)-3,7-Dimethyl-1-((1S,4As,8As)-5,5,8A-Trimethyl-2-Methylene-Decahydronaphthalen-1-Yl)Non-7-En-2-Yl Sulfate 2
NPC270918 6-Hydroxy-3,4-Dihydro-1-Oxo-Beta-Carboline 2
NPC220311 5,5'-Methylenebis(3,4-Dibromobenzene-1,2-Diol) 2
NPC75557 5-((R,5Z,9Z)-13-(Furan-3-Yl)-2,6,10-Trimethyltrideca-5,9-Dienylidene)-4-Hydroxy-3-Methylfuran-2(5H)-One 1
NPC324405 Sodium(E)-((1R,4As,4Bs,8As,10As)-4B,8,8,10A-Tetramethyl-1-(2-(2-Oxo-2,5-Dihydro-1H-Pyrrol-3-Yl)Ethyl)Decahydrophenanthren-2(1H,3H,4Bh)-Ylidene)Methyl Sulfate 1
NPC190086 Sargachromanol M 1
NPC475045 Methyl 2-[5-Hydroxy-2-[(6E,10E,13S)-13-Hydroxy-3,7,11,15-Tetramethyl-12-Oxohexadeca-1,6,10,14-Tetraen-3-Yl]Oxyphenyl]Acetate 1
NPC477797 [(E)-2-[2-[(3,4-dihydroxyphenyl)-hydroxymethyl]-1,3-benzodioxol-5-yl]ethenyl] sulfate 1
NPC283284 (7E,12E,18R,20Z)-Variabilin 1
NPC475706 (5Z)-4-Hydroxy-5-[(2R,5Z,9Z)-13-(2-Hydroxy-5-Oxo-2H-Furan-3-Yl)-2,6,10-Trimethyltrideca-5,9-Dienylidene]-3-Methylfuran-2-One 1
NPC196621 Sargachromanol P 1
NPC474943 Methyl 2-[5-Hydroxy-2-[(6E,10E,12S)-12-Hydroxy-3,7,11,15-Tetramethyl-13-Oxohexadeca-1,6,10,14-Tetraen-3-Yl]Oxyphenyl]Acetate 1
NPC477796 [(Z)-2-[2-[(3,4-dihydroxyphenyl)-[4-[2-(dimethylamino)ethyl]imidazol-1-yl]methyl]-1,3-benzodioxol-5-yl]ethenyl] sulfate 1
NPC46586 Sargachromanol E 1
NPC474411 2-[4-[(3E,7E,12R,14R)-14,15-Dihydroxy-16-Methoxy-14-Methoxycarbonyl-4,8,12,15-Tetramethyl-16-Oxohexadeca-3,7-Dienyl]-5-Oxo-2H-Pyrrol-1-Yl]Acetic Acid 1
NPC8538 Bahamaolide A 1
NPC144745 (R,6Z,10Z)-14-(Furan-3-Yl)-3,7,11-Trimethyltetradeca-6,10-Dienoic Acid 1
NPC325960 Sodium(E)-((1R,4As,4Bs,8As,10As)-1-(2-((S)-5-Methoxy-2-Oxo-2,5-Dihydrofuran-3-Yl)Ethyl)-4B,8,8,10A-Tetramethyldecahydrophenanthren-2(1H,3H,4Bh)-Ylidene)Methyl Sulfate 1
NPC476018 Nahocol D1 1
NPC475005 Methyl 2-[5-Hydroxy-2-[(6E,10Z,12S)-12-Hydroxy-3,7,11,15-Tetramethyl-13-Oxohexadeca-1,6,10,14-Tetraen-3-Yl]Oxyphenyl]Acetate 1
NPC477795 [(Z)-2-[2-[(3,4-dihydroxyphenyl)-[4-[2-(dimethylamino)ethyl]imidazol-1-yl]methyl]-1,3-benzodioxol-5-yl]ethenyl] sulfate 1
NPC474431 2-[4-[(4Z,8Z,12R,14R)-14,15-Dihydroxy-16-Methoxy-14-Methoxycarbonyl-4,8,12,15-Tetramethyl-16-Oxohexadeca-4,8-Dienyl]-5-Oxo-2H-Pyrrol-1-Yl]Acetic Acid 1
NPC476020 (6E,10E)-16-(2,5-Dihydroxy-3-Methylphenyl)-4,14-Dihydroxy-2,6,10,14-Tetramethylhexadeca-2,6,10-Trien-5-One 1
NPC327527 Suvanine's Sodium Salt 1
NPC474237 Sargachromanol O 1
NPC475012 Methyl 2-(2-((E)-3,7-Dimethyl-8-((1R,5R)-3-Methyl-5-(2-Methylprop-1-Enyl)-4-Oxocyclopent-2-Enyl)Octa-1,6-Dien-3-Yloxy)-5-Hydroxyphenyl)Acetate 1
NPC477039 n.a. 1
NPC276962 Sargachromano N 1
NPC476025 Nahocol A 1
NPC474143 Sargachromanol I 1
NPC177967 Z/E-Synoilide A 1
NPC114918 Sargahydroquinoic Acid 1
NPC477038 [(E)-2-[3-(furan-3-yl)propyl]-6-methyl-8-[(1S,6R)-1,2,6-trimethylcyclohex-2-en-1-yl]oct-5-enyl] sulfate 1
NPC474424 (5Z)-4-Hydroxy-5-[(2R,6E,10E)-13-(2-Hydroxy-5-Oxo-2H-Furan-4-Yl)-2,6,10-Trimethyltrideca-6,10-Dienylidene]-3-Methylfuran-2-One 1
NPC475011 Methyl 2-[5-Hydroxy-2-[(6E,13E)-12-Hydroxy-3,7,11,15-Tetramethylhexadeca-1,6,13,15-Tetraen-3-Yl]Oxyphenyl]Acetate 1
NPC475714 5-((R,5Z,9Z)-13-(2,5-Dimethoxy-2,5-Dihydrofuran-3-Yl)-2,6,10-Trimethyltrideca-5,9-Dienylidene)-4-Hydroxy-3-Methylfuran-2(5H)-One 1
NPC474407 (2R)-Dimethyl 2-((R,6E,10E)-13-(Furan-3-Yl)-2,6,10-Trimethyltrideca-6,10-Dienyl)-2,3-Dihydroxy-3-Methylsuccinate 1
NPC147896 Sargachromanol A 1
NPC477040 n.a. 1
NPC67183 (3R,6Z,10Z)-14-(2,5-Dioxofuran-3-Yl)-3,7,11-Trimethyltetradeca-6,10-Dienoic Acid 1
NPC204535 Sargachromano D 1
NPC470500 Eudistomin Y8 1
NPC208906 (R,7E,11E)-14-(Furan-3-Yl)-3,7,11-Trimethyltetradeca-7,11-Dienoic Acid 1
NPC477798 [(E)-2-[2-[(3,4-dihydroxyphenyl)-hydroxymethyl]-1,3-benzodioxol-5-yl]ethenyl] sulfate 1
NPC232295 Sargachromanol C 1
NPC477794 [(E)-2-[2-(3,4-dihydroxyphenyl)-3-[2-hydroxy-4-[(E)-2-sulfonatooxyethenyl]phenoxy]-2,3-dihydro-1,4-benzodioxin-6-yl]ethenyl] sulfate 1
NPC471235 Cadiolide H 1
NPC27041 Eudistomin Y1 1
NPC474425 (2S)-Dimethyl 2-((R,5Z,9Z)-13-(Furan-3-Yl)-2,6,10-Trimethyltrideca-5,9-Dienyl)-2,3-Dihydroxy-3-Methylsuccinate 1
NPC477800 [(E)-2-[3-(3,4-dihydroxyphenyl)-2-[2-hydroxy-4-[(E)-2-sulfonatooxyethenyl]phenoxy]-2,3-dihydro-1,4-benzodioxin-6-yl]ethenyl] sulfate 1
NPC474130 Sargachromanol F 1
NPC477802 Isojaspisin 1
NPC471237 Synoilide A 1
NPC317217 Halisulfate 2 1
NPC279189 Eudistomin Y2 1
NPC474426 (2R)-Dimethyl 2-((R,5Z,9Z)-13-(Furan-3-Yl)-2,6,10-Trimethyltrideca-5,9-Dienyl)-2,3-Dihydroxy-3-Methylsuccinate 1
NPC476925 Suvanine 1
NPC271832 Sargachromanol G 1
NPC62867 Coscinoquinol 1
NPC471236 Synoilide B 1
NPC318515 Sodium(E)-((1R,4As,4Bs,8As,10As)-4B,8,8,10A-Tetramethyl-1-(2-(5-Oxo-2,5-Dihydrofuran-3-Yl)Ethyl)Decahydrophenanthren-2(1H,3H,4Bh)-Ylidene)Methyl Sulfate 1
NPC200553 Eudistomin Y3 1
NPC477037 [(E,2R,3R)-1-[(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]-9-(2,5-dihydroxyphenyl)-3,7-dimethylnon-7-en-2-yl] hydrogen sulfate 1
NPC245386 Bis(2,3-Dibromo-4,5-Dihydroxybenzyl)Ether 1
NPC318581 Sodium;[(Z,2R,3R)-1-[(1S,4As,8As)-2,5,5,8A-Tetramethyl-1,4,4A,6,7,8-Hexahydronaphthalen-1-Yl]-9-(2,5-Dihydroxyphenyl)-3,7-Dimethylnon-7-En-2-Yl] Sulfate 1
NPC32152 Sargachromanol B 1
NPC475044 Methyl 2-[5-Hydroxy-2-[(6E)-12-Hydroxy-3,7,11,15-Tetramethyl-13-Oxohexadeca-1,6,14-Trien-3-Yl]Oxyphenyl]Acetate 1
NPC477799 [(E)-2-[3-(3,4-dihydroxyphenyl)-2-[2-hydroxy-4-[(E)-2-sulfonatooxyethenyl]phenoxy]-2,3-dihydro-1,4-benzodioxin-6-yl]ethenyl] sulfate 1
NPC59654 Sargachromanol K 1
NPC319030 Sodium(E)-((1R,4As,4Bs,8As,10As)-1-(2-((2S,3S,4R,5R)-3,4-Dihydroxy-2,5-Dimethoxytetrahydrofuran-3-Yl)Ethyl)-4B,8,8,10A-Tetramethyldecahydrophenanthren-2(1H,3H,4Bh)-Ylidene)Methyl Sulfate 1
NPC475028 Nahocol A1 1
NPC477803 4-(1,2,2-trimethoxyethyl)benzene-1,2-diol 1
NPC475880 Sargachromanol H 1
NPC475063 Methyl 2-[5-Hydroxy-2-[(6E,12R)-12-Hydroxy-3,7,11,15-Tetramethyl-13-Oxohexadeca-1,6,14-Trien-3-Yl]Oxyphenyl]Acetate 1
NPC319692 Sodium(E)-((1R,4As,4Bs,8As,10As)-1-(2-((R)-5-Methoxy-2-Oxo-2,5-Dihydrofuran-3-Yl)Ethyl)-4B,8,8,10A-Tetramethyldecahydrophenanthren-2(1H,3H,4Bh)-Ylidene)Methyl Sulfate 1
NPC477801 Jaspisin 1
NPC474131 Sargachromanol L 1
NPC470504 Eudistomin Y12 1
NPC477804 [(E)-2-[3-(3,4-dihydroxyphenyl)-2-sulfonatooxy-2,3-dihydro-1,4-benzodioxin-6-yl]ethenyl] sulfate 1
NPC475029 Nahocol D2 1
NPC324078 Sodium(E)-((1R,4As,4Bs,8As,10As)-1-(2-((S)-2-Hydroxy-5-Oxo-2,5-Dihydrofuran-3-Yl)Ethyl)-4B,8,8,10A-Tetramethyldecahydrophenanthren-2(1H,3H,4Bh)-Ylidene)Methyl Sulfate 1
NPC470505 Eudistomin Y13 1
NPC474438 5-((2R,E)-13-(Furan-3-Yl)-10-Hydroxy-2,6,10-Trimethyltridec-6-Enylidene)-4-Hydroxy-3-Methylfuran-2(5H)-One 1
NPC477805 [(E)-2-[2-[(3,4-dihydroxyphenyl)-[4-[2-(dimethylamino)ethyl]imidazol-1-yl]methyl]-1,3-benzodioxol-5-yl]ethenyl] sulfate 1
NPC197766 Z/E-Synoilide B 1
NPC324243 Sodium(E)-((1R,4As,4Bs,8As,10As)-1-(2-((2S,5R)-2,5-Dimethoxy-2,5-Dihydrofuran-3-Yl)Ethyl)-4B,8,8,10A-Tetramethyldecahydrophenanthren-2(1H,3H,4Bh)-Ylidene)Methyl Sulfate 1
NPC474246 Sargachromanol J 1
NPC474439 5-((R,6E,10E)-13-(2,5-Dimethoxy-2,5-Dihydrofuran-3-Yl)-2,6,10-Trimethyltrideca-6,10-Dienylidene)-4-Hydroxy-3-Methylfuran-2(5H)-One 1
NPC477806 [(E)-2-[2-[(3,4-dihydroxyphenyl)-[4-[2-(dimethylamino)ethyl]imidazol-1-yl]methyl]-1,3-benzodioxol-5-yl]ethenyl] sulfate 1
NPC73132 Z/E-Cadiolide H 1

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