Drug Information| Drug ID:   | NPD601 |
| Drug Name:   | Isoproterenol |
| Molecular Formula:   | C11H17NO3 |
| Canonical SMILES:   | CC(NCC(c1ccc(c(c1)O)O)O)C |
| Standard InCHI:   | "InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3" |
| Standard InCHIKey:   | JWZZKOKVBUJMES-UHFFFAOYSA-N |
| Max Developmental Stage:   | Phase 4 |
| Max Developmental Stage Source:   | TTD; ChEMBL; IUPHAR/BPS |
  Structural Similarity Between NPASS Natural Products and NPD601Similarity is measured using the Tanimoto coefficient (Tc) , which compares the binary fingerprints of two molecules. Tc is calculated as the intersection divided by the union of '1' bits in the fingerprints, ranging from 0 to 1, with 1 indicating highest similarity.
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.
  Similar Natural Products High Similarity: Tc>=0.85; Intermediate Similarity: 0.7 <= Tc < 0.85; Remote Similarity: 0.5 <= Tc < 0.7
| Similarity Level | Similarity Score | Natural Product ID |
|---|---|---|
| High Similarity | 1.0 | NPC483291 |
| High Similarity | 1.0 | NPC611998 |
| Intermediate Similarity | 0.7353 | NPC323775 |
| Intermediate Similarity | 0.7353 | NPC236347 |
| Intermediate Similarity | 0.7353 | NPC599888 |
| Intermediate Similarity | 0.7353 | NPC611709 |
| Remote Similarity | 0.6667 | NPC118522 |
| Remote Similarity | 0.6667 | NPC115627 |
| Remote Similarity | 0.6667 | NPC169207 |
| Remote Similarity | 0.6667 | NPC599811 |
| Remote Similarity | 0.6667 | NPC602688 |
| Remote Similarity | 0.5227 | NPC130592 |
| Remote Similarity | 0.5116 | NPC141126 |
| Molecular Weight   | 211.12 |
| ALogP   | -1.7879 |
| MLogP   | 2.23 |
| XLogP   | 0.813 |
| HDA   | 2 |
| HBD   | 4 |
| Rotatable Bonds   | 9 |
| TPSA   | 72.72 |
| RO5 Violation   | 0 |