Drug Information

Drug ID:  NPD385
Drug Name:  Menthol; (-)-menthol
Molecular Formula:  C10H20O
Canonical SMILES:  C[C@@H]1CC[C@H]([C@@H](C1)O)C(C)C
Standard InCHI:  InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1
Standard InCHIKey:  NOOLISFMXDJSKH-KXUCPTDWSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  TTD; DrugBank; IUPHAR/BPS

  Structural Similarity Between NPASS Natural Products and NPD385

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
High Similarity 1.0 NPC84030
High Similarity 1.0 NPC198540
High Similarity 1.0 NPC287550
High Similarity 1.0 NPC223468
High Similarity 1.0 NPC147343
High Similarity 1.0 NPC176309
High Similarity 0.8864 NPC144891
High Similarity 0.86 NPC53209
Intermediate Similarity 0.8367 NPC307022
Intermediate Similarity 0.8077 NPC471269
Intermediate Similarity 0.8077 NPC67508
Intermediate Similarity 0.8077 NPC84824
Intermediate Similarity 0.7963 NPC47663
Intermediate Similarity 0.7907 NPC177022
Intermediate Similarity 0.7818 NPC185116
Intermediate Similarity 0.7778 NPC236588
Intermediate Similarity 0.7778 NPC135438
Intermediate Similarity 0.7778 NPC160261
Intermediate Similarity 0.7778 NPC469759
Intermediate Similarity 0.7755 NPC314087
Intermediate Similarity 0.7736 NPC166894
Intermediate Similarity 0.7736 NPC89069
Intermediate Similarity 0.7736 NPC277917
Intermediate Similarity 0.7736 NPC283655
Intermediate Similarity 0.7736 NPC178223
Intermediate Similarity 0.7708 NPC77550
Intermediate Similarity 0.7708 NPC108441
Intermediate Similarity 0.7647 NPC274261
Intermediate Similarity 0.7647 NPC291724
Intermediate Similarity 0.7636 NPC475515
Intermediate Similarity 0.7636 NPC215671
Intermediate Similarity 0.7636 NPC87296
Intermediate Similarity 0.7556 NPC221022
Intermediate Similarity 0.7544 NPC95804
Intermediate Similarity 0.7544 NPC185547
Intermediate Similarity 0.7455 NPC150713
Intermediate Similarity 0.7455 NPC29976
Intermediate Similarity 0.7414 NPC292419
Intermediate Similarity 0.7414 NPC290791
Intermediate Similarity 0.7358 NPC36002
Intermediate Similarity 0.7358 NPC102336
Intermediate Similarity 0.7347 NPC473914
Intermediate Similarity 0.7288 NPC101128
Intermediate Similarity 0.7288 NPC94897
Intermediate Similarity 0.7273 NPC328441
Intermediate Similarity 0.7255 NPC316035
Intermediate Similarity 0.7255 NPC294858
Intermediate Similarity 0.7241 NPC218585
Intermediate Similarity 0.7241 NPC148174
Intermediate Similarity 0.7241 NPC71460
Intermediate Similarity 0.7209 NPC283682
Intermediate Similarity 0.72 NPC14552
Intermediate Similarity 0.7167 NPC41577
Intermediate Similarity 0.7167 NPC2728
Intermediate Similarity 0.7167 NPC474380
Intermediate Similarity 0.7167 NPC282619
Intermediate Similarity 0.7167 NPC473276
Intermediate Similarity 0.7167 NPC80463
Intermediate Similarity 0.7167 NPC11555
Intermediate Similarity 0.7167 NPC172613
Intermediate Similarity 0.7167 NPC60837
Intermediate Similarity 0.7167 NPC260116
Intermediate Similarity 0.7167 NPC208198
Intermediate Similarity 0.7143 NPC240994
Intermediate Similarity 0.7143 NPC313795
Intermediate Similarity 0.7143 NPC215358
Intermediate Similarity 0.7119 NPC209686
Intermediate Similarity 0.7119 NPC236099
Intermediate Similarity 0.7119 NPC249078
Intermediate Similarity 0.7119 NPC114891
Intermediate Similarity 0.7091 NPC300189
Intermediate Similarity 0.7049 NPC44122
Intermediate Similarity 0.7049 NPC473929
Intermediate Similarity 0.7049 NPC142712
Intermediate Similarity 0.7037 NPC161473
Intermediate Similarity 0.7 NPC159654
Intermediate Similarity 0.7 NPC281540
Intermediate Similarity 0.7 NPC68656
Intermediate Similarity 0.7 NPC225415
Intermediate Similarity 0.7 NPC118937
Intermediate Similarity 0.7 NPC219940
Intermediate Similarity 0.7 NPC167995
Intermediate Similarity 0.7 NPC144650
Intermediate Similarity 0.7 NPC69149
Remote Similarity 0.6977 NPC1748
Remote Similarity 0.6977 NPC66124
Remote Similarity 0.6977 NPC193062
Remote Similarity 0.6977 NPC319034
Remote Similarity 0.6977 NPC72324
Remote Similarity 0.6964 NPC170780
Remote Similarity 0.6964 NPC3025
Remote Similarity 0.6935 NPC48079
Remote Similarity 0.6935 NPC185874
Remote Similarity 0.6935 NPC473230
Remote Similarity 0.6935 NPC269077
Remote Similarity 0.6935 NPC139207
Remote Similarity 0.6935 NPC204233
Remote Similarity 0.6935 NPC475884
Remote Similarity 0.6935 NPC253303
Remote Similarity 0.6909 NPC32222
Remote Similarity 0.6909 NPC202146
Remote Similarity 0.6889 NPC61665
Remote Similarity 0.6885 NPC300442
Remote Similarity 0.6885 NPC258595
Remote Similarity 0.6852 NPC476149
Remote Similarity 0.6852 NPC300235
Remote Similarity 0.6852 NPC244869
Remote Similarity 0.6852 NPC476136
Remote Similarity 0.6825 NPC474756
Remote Similarity 0.6825 NPC244790
Remote Similarity 0.6825 NPC266578
Remote Similarity 0.6825 NPC469987
Remote Similarity 0.6825 NPC475893
Remote Similarity 0.6825 NPC472741
Remote Similarity 0.6774 NPC475897
Remote Similarity 0.6744 NPC267243
Remote Similarity 0.6744 NPC122962
Remote Similarity 0.6724 NPC476735
Remote Similarity 0.6724 NPC474769
Remote Similarity 0.6724 NPC189290
Remote Similarity 0.6719 NPC210323
Remote Similarity 0.6719 NPC470833
Remote Similarity 0.6719 NPC129829
Remote Similarity 0.6719 NPC299948
Remote Similarity 0.6719 NPC107919
Remote Similarity 0.6719 NPC66407
Remote Similarity 0.6719 NPC254037
Remote Similarity 0.6719 NPC234511
Remote Similarity 0.6719 NPC470830
Remote Similarity 0.6719 NPC241085
Remote Similarity 0.6719 NPC477820
Remote Similarity 0.6667 NPC472984
Remote Similarity 0.6667 NPC476928
Remote Similarity 0.6667 NPC210316
Remote Similarity 0.6667 NPC251335
Remote Similarity 0.6667 NPC87439
Remote Similarity 0.6667 NPC97967
Remote Similarity 0.6667 NPC63190
Remote Similarity 0.6615 NPC63588
Remote Similarity 0.6615 NPC232925
Remote Similarity 0.6615 NPC45296
Remote Similarity 0.6615 NPC231945
Remote Similarity 0.6615 NPC251201
Remote Similarity 0.6615 NPC92801
Remote Similarity 0.6615 NPC192192
Remote Similarity 0.6615 NPC283316
Remote Similarity 0.6615 NPC282454
Remote Similarity 0.6613 NPC472946
Remote Similarity 0.661 NPC95958
Remote Similarity 0.66 NPC302939
Remote Similarity 0.66 NPC287331
Remote Similarity 0.6562 NPC96484
Remote Similarity 0.6562 NPC276616
Remote Similarity 0.6562 NPC2648
Remote Similarity 0.6562 NPC245795
Remote Similarity 0.6552 NPC291147
Remote Similarity 0.6552 NPC119425
Remote Similarity 0.6522 NPC474392
Remote Similarity 0.6522 NPC474914
Remote Similarity 0.6515 NPC110799
Remote Similarity 0.6515 NPC131506
Remote Similarity 0.6515 NPC470071
Remote Similarity 0.6515 NPC127094
Remote Similarity 0.6515 NPC187471
Remote Similarity 0.6515 NPC89310
Remote Similarity 0.6515 NPC478103
Remote Similarity 0.6515 NPC301226
Remote Similarity 0.6515 NPC109457
Remote Similarity 0.6515 NPC242992
Remote Similarity 0.6515 NPC252182
Remote Similarity 0.6515 NPC195530
Remote Similarity 0.6515 NPC1340
Remote Similarity 0.6515 NPC157422
Remote Similarity 0.6515 NPC473279
Remote Similarity 0.6515 NPC23954
Remote Similarity 0.6515 NPC111234
Remote Similarity 0.6515 NPC157777
Remote Similarity 0.6515 NPC164022
Remote Similarity 0.6515 NPC100586
Remote Similarity 0.6515 NPC167706
Remote Similarity 0.6512 NPC24506
Remote Similarity 0.6512 NPC112242
Remote Similarity 0.6512 NPC225783
Remote Similarity 0.6512 NPC147096
Remote Similarity 0.6512 NPC236797
Remote Similarity 0.6512 NPC163556
Remote Similarity 0.6512 NPC185041
Remote Similarity 0.6508 NPC202017
Remote Similarity 0.6508 NPC326310
Remote Similarity 0.65 NPC475412
Remote Similarity 0.6462 NPC213178
Remote Similarity 0.6462 NPC327728
Remote Similarity 0.6462 NPC6120
Remote Similarity 0.6462 NPC131892
Remote Similarity 0.6452 NPC96793
Remote Similarity 0.6452 NPC323424
Remote Similarity 0.6441 NPC240206
Remote Similarity 0.6418 NPC95165
Remote Similarity 0.6418 NPC470610
Remote Similarity 0.6418 NPC201373

Drug Structure

External Identifiers

TTD   DAP000876
DrugBank   DB00825
ChEMBL   CHEMBL470670
IUPHAR/BPS   2430
PharmaGKB   PA164776605
KEGG Drug   D00064
PubChem CID   16666
ChEBI   15409
CAS Number  2216-51-5

Drug Properties

Molecular Weight  156.15
ALogP  0.6563
MLogP  2.45
XLogP  3.211
HDA  1
HBD  1
Rotatable Bonds  5
TPSA  20.23
RO5 Violation  0