Drug Information

Drug ID:  NPD1281
Drug Name:  Naproxen Sodium
Molecular Formula:  C14H14O3.Na
Canonical SMILES:  COc1ccc2c(c1)ccc(c2)[C@@H](C(=O)[O-])C.[Na+]
Standard InCHI:  InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
Standard InCHIKey:  CDBRNDSHEYLDJV-FVGYRXGTSA-M
Max Developmental Stage:  Approved
Max Developmental Stage Source:  ChEMBL

  Structural Similarity Between NPASS Natural Products and NPD1281

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
High Similarity 0.9744 NPC111088
High Similarity 0.8824 NPC328694
High Similarity 0.878 NPC75432
High Similarity 0.8718 NPC109241
High Similarity 0.8672 NPC183103
High Similarity 0.864 NPC474737
High Similarity 0.8596 NPC1065
High Similarity 0.8571 NPC428300
High Similarity 0.8538 NPC213122
Intermediate Similarity 0.8492 NPC177925
Intermediate Similarity 0.843 NPC25648
Intermediate Similarity 0.8421 NPC241224
Intermediate Similarity 0.8376 NPC234639
Intermediate Similarity 0.8374 NPC478121
Intermediate Similarity 0.8372 NPC470725
Intermediate Similarity 0.832 NPC121168
Intermediate Similarity 0.8308 NPC164295
Intermediate Similarity 0.8308 NPC239134
Intermediate Similarity 0.8281 NPC223807
Intermediate Similarity 0.8264 NPC283169
Intermediate Similarity 0.8261 NPC38209
Intermediate Similarity 0.8246 NPC300166
Intermediate Similarity 0.8235 NPC470723
Intermediate Similarity 0.8226 NPC103916
Intermediate Similarity 0.8209 NPC186647
Intermediate Similarity 0.8197 NPC312105
Intermediate Similarity 0.8188 NPC290038
Intermediate Similarity 0.8182 NPC470406
Intermediate Similarity 0.8174 NPC298224
Intermediate Similarity 0.8168 NPC279596
Intermediate Similarity 0.816 NPC241001
Intermediate Similarity 0.8154 NPC57552
Intermediate Similarity 0.8148 NPC233707
Intermediate Similarity 0.8148 NPC475104
Intermediate Similarity 0.8125 NPC232387
Intermediate Similarity 0.812 NPC209858
Intermediate Similarity 0.812 NPC324117
Intermediate Similarity 0.812 NPC27394
Intermediate Similarity 0.812 NPC274876
Intermediate Similarity 0.8115 NPC322358
Intermediate Similarity 0.8106 NPC312560
Intermediate Similarity 0.8092 NPC475102
Intermediate Similarity 0.8074 NPC290601
Intermediate Similarity 0.8067 NPC259554
Intermediate Similarity 0.8065 NPC63010
Intermediate Similarity 0.8065 NPC205502
Intermediate Similarity 0.8062 NPC474264
Intermediate Similarity 0.806 NPC88065
Intermediate Similarity 0.806 NPC95485
Intermediate Similarity 0.806 NPC470844
Intermediate Similarity 0.806 NPC89504
Intermediate Similarity 0.8058 NPC260152
Intermediate Similarity 0.8058 NPC471305
Intermediate Similarity 0.8047 NPC470163
Intermediate Similarity 0.8047 NPC470162
Intermediate Similarity 0.8045 NPC472524
Intermediate Similarity 0.803 NPC258073
Intermediate Similarity 0.8029 NPC29599
Intermediate Similarity 0.8029 NPC472523
Intermediate Similarity 0.8017 NPC280760
Intermediate Similarity 0.8016 NPC129176
Intermediate Similarity 0.8015 NPC206028
Intermediate Similarity 0.8 NPC471670
Intermediate Similarity 0.8 NPC234956
Intermediate Similarity 0.8 NPC42657
Intermediate Similarity 0.7986 NPC472840
Intermediate Similarity 0.7985 NPC1249
Intermediate Similarity 0.7984 NPC469954
Intermediate Similarity 0.7969 NPC182646
Intermediate Similarity 0.7967 NPC51345
Intermediate Similarity 0.7958 NPC95526
Intermediate Similarity 0.7958 NPC127827
Intermediate Similarity 0.7956 NPC470407
Intermediate Similarity 0.7955 NPC249425
Intermediate Similarity 0.7953 NPC249340
Intermediate Similarity 0.7953 NPC162935
Intermediate Similarity 0.7943 NPC473927
Intermediate Similarity 0.7943 NPC163846
Intermediate Similarity 0.7943 NPC225173
Intermediate Similarity 0.7941 NPC156888
Intermediate Similarity 0.7941 NPC6100
Intermediate Similarity 0.7941 NPC470721
Intermediate Similarity 0.7941 NPC470722
Intermediate Similarity 0.7939 NPC181675
Intermediate Similarity 0.792 NPC171023
Intermediate Similarity 0.792 NPC293424
Intermediate Similarity 0.791 NPC205915
Intermediate Similarity 0.7907 NPC89630
Intermediate Similarity 0.7907 NPC107846
Intermediate Similarity 0.7907 NPC56332
Intermediate Similarity 0.7907 NPC30216
Intermediate Similarity 0.7903 NPC33900
Intermediate Similarity 0.7902 NPC261322
Intermediate Similarity 0.7902 NPC472298
Intermediate Similarity 0.7902 NPC300983
Intermediate Similarity 0.7902 NPC475722
Intermediate Similarity 0.7899 NPC168471
Intermediate Similarity 0.7899 NPC246474
Intermediate Similarity 0.7899 NPC162851
Intermediate Similarity 0.7899 NPC218092
Intermediate Similarity 0.7891 NPC476332
Intermediate Similarity 0.7891 NPC473464
Intermediate Similarity 0.7891 NPC176208
Intermediate Similarity 0.7891 NPC152946
Intermediate Similarity 0.7887 NPC181464
Intermediate Similarity 0.7887 NPC125801
Intermediate Similarity 0.7874 NPC212559
Intermediate Similarity 0.7874 NPC100108
Intermediate Similarity 0.7874 NPC277798
Intermediate Similarity 0.7868 NPC475549
Intermediate Similarity 0.7863 NPC100129
Intermediate Similarity 0.7863 NPC12870
Intermediate Similarity 0.7863 NPC24327
Intermediate Similarity 0.7857 NPC158871
Intermediate Similarity 0.7852 NPC68779
Intermediate Similarity 0.7852 NPC5310
Intermediate Similarity 0.7852 NPC300776
Intermediate Similarity 0.7852 NPC4982
Intermediate Similarity 0.7852 NPC311339
Intermediate Similarity 0.7852 NPC176814
Intermediate Similarity 0.7851 NPC473809
Intermediate Similarity 0.784 NPC240664
Intermediate Similarity 0.784 NPC45104
Intermediate Similarity 0.7833 NPC75440
Intermediate Similarity 0.7832 NPC24193
Intermediate Similarity 0.7829 NPC473942
Intermediate Similarity 0.7829 NPC470887
Intermediate Similarity 0.7826 NPC476191
Intermediate Similarity 0.7823 NPC220540
Intermediate Similarity 0.782 NPC245395
Intermediate Similarity 0.782 NPC27659
Intermediate Similarity 0.7812 NPC177291
Intermediate Similarity 0.7812 NPC194416
Intermediate Similarity 0.7805 NPC165106
Intermediate Similarity 0.7805 NPC141003
Intermediate Similarity 0.7805 NPC35344
Intermediate Similarity 0.7801 NPC300603
Intermediate Similarity 0.7801 NPC472836
Intermediate Similarity 0.7801 NPC91694
Intermediate Similarity 0.7801 NPC308006
Intermediate Similarity 0.7794 NPC113295
Intermediate Similarity 0.7794 NPC211386
Intermediate Similarity 0.7794 NPC22644
Intermediate Similarity 0.7793 NPC118332
Intermediate Similarity 0.7787 NPC23332
Intermediate Similarity 0.7786 NPC125134
Intermediate Similarity 0.7786 NPC86455
Intermediate Similarity 0.7786 NPC137920
Intermediate Similarity 0.7786 NPC94076
Intermediate Similarity 0.7786 NPC201297
Intermediate Similarity 0.7786 NPC182255
Intermediate Similarity 0.777 NPC165172
Intermediate Similarity 0.7769 NPC273837
Intermediate Similarity 0.7761 NPC301717
Intermediate Similarity 0.776 NPC19290
Intermediate Similarity 0.7754 NPC265335
Intermediate Similarity 0.7752 NPC30462
Intermediate Similarity 0.7744 NPC131684
Intermediate Similarity 0.7742 NPC221275
Intermediate Similarity 0.774 NPC44606
Intermediate Similarity 0.7737 NPC115861
Intermediate Similarity 0.7734 NPC259703
Intermediate Similarity 0.7734 NPC322569
Intermediate Similarity 0.7734 NPC32322
Intermediate Similarity 0.7731 NPC238115
Intermediate Similarity 0.7731 NPC473855
Intermediate Similarity 0.773 NPC474036
Intermediate Similarity 0.773 NPC84266
Intermediate Similarity 0.7727 NPC53781
Intermediate Similarity 0.7727 NPC45537
Intermediate Similarity 0.7724 NPC119929
Intermediate Similarity 0.7724 NPC199462
Intermediate Similarity 0.7721 NPC110958
Intermediate Similarity 0.7721 NPC19890
Intermediate Similarity 0.7717 NPC264976
Intermediate Similarity 0.7714 NPC149780
Intermediate Similarity 0.771 NPC4286
Intermediate Similarity 0.771 NPC165556
Intermediate Similarity 0.771 NPC105031
Intermediate Similarity 0.771 NPC76119
Intermediate Similarity 0.771 NPC53305
Intermediate Similarity 0.771 NPC17348
Intermediate Similarity 0.771 NPC257589
Intermediate Similarity 0.7705 NPC475852
Intermediate Similarity 0.7705 NPC303521
Intermediate Similarity 0.7705 NPC183648
Intermediate Similarity 0.7704 NPC474340
Intermediate Similarity 0.7698 NPC1268
Intermediate Similarity 0.7698 NPC223336
Intermediate Similarity 0.7692 NPC39361
Intermediate Similarity 0.7692 NPC474691
Intermediate Similarity 0.7692 NPC275145
Intermediate Similarity 0.7692 NPC60389
Intermediate Similarity 0.7692 NPC320287
Intermediate Similarity 0.7692 NPC211565
Intermediate Similarity 0.7692 NPC58752
Intermediate Similarity 0.7687 NPC253488
Intermediate Similarity 0.7687 NPC473271
Intermediate Similarity 0.7687 NPC477691
Intermediate Similarity 0.7686 NPC201959

Drug Structure

External Identifiers

TTD  
DrugBank  
ChEMBL  
IUPHAR/BPS  
PharmaGKB  
KEGG Drug  
PubChem CID  
ChEBI  
CAS Number  

Drug Properties

Molecular Weight  229.09
ALogP  -0.6746
MLogP  2.67
XLogP  3.269
HDA  2
HBD  0
Rotatable Bonds  6
TPSA  49.36
RO5 Violation  0