| Target ID | Target Name | Target Organism | # Natural Product | # Activity Record |
|---|---|---|---|---|
| NPT463 | HMG-CoA reductase | Rattus norvegicus | 5 | 21 |
| NPT2954 | Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic | Mus musculus | 4 | 4 |
| NPT4862 | 11-beta-hydroxysteroid dehydrogenase 1 | Mus musculus | 16 | 28 |
| NPT4861 | 11-beta-hydroxysteroid dehydrogenase 2 | Mus musculus | 10 | 10 |
| NPT683 | Aldehyde reductase | Homo sapiens | 3 | 3 |
| NPT680 | Aldehyde reductase | Rattus norvegicus | 2 | 3 |
| NPT4260 | 11-beta-hydroxysteroid dehydrogenase 1 | Rattus norvegicus | 3 | 8 |
| NPT3582 | Ketopantoate reductase | Escherichia coli K-12 | 8 | 11 |
| NPT1334 | 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum | 16 | 21 |
| NPT1335 | Glucose-6-phosphate 1-dehydrogenase | Saccharomyces cerevisiae S288c | 8 | 8 |
| NPT1336 | 6-phosphogluconate dehydrogenase | Homo sapiens | 9 | 10 |
| NPT1564 | Malate dehydrogenase | Thermus thermophilus | 5 | 5 |
| NPT3945 | 1-deoxyxylulose-5-phosphate reductoisomerase | Escherichia coli K-12 | 2 | 11 |
| NPT3946 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycobacterium tuberculosis | 2 | 11 |
| NPT1578 | Aldose reductase | Sus scrofa | 7 | 7 |
| NPT1576 | Aldo-keto reductase family 1 member C21 | Mus musculus | 4 | 5 |
| NPT1576 | Aldo-keto reductase family 1 member C21 | Mus musculus | 4 | 5 |
| NPT1551 | Sorbitol dehydrogenase | Homo sapiens | 13 | 14 |
| NPT2684 | Malate dehydrogenase mitochondrial | Sus scrofa | 7 | 8 |
| NPT2683 | Malate dehydrogenase cytoplasmic | Homo sapiens | 6 | 7 |
| NPT2683 | Malate dehydrogenase cytoplasmic | Homo sapiens | 6 | 7 |
| NPT3947 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | 2 | 3 |
| NPT2666 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Schizosaccharomyces pombe 972h- | 3 | 3 |
| NPT5062 | Estradiol 17-beta-dehydrogenase 12 | Homo sapiens | 1 | 2 |
| NPT5062 | Estradiol 17-beta-dehydrogenase 12 | Homo sapiens | 1 | 2 |
| NPT1565 | Aldose reductase | Oryctolagus cuniculus | 1 | 2 |
| NPT1587 | Estradiol 17-beta-dehydrogenase 1 | Homo sapiens | 18 | 43 |
| NPT1581 | Carbonyl reductase [NADPH] 1 | Homo sapiens | 7 | 17 |
| NPT1581 | Carbonyl reductase [NADPH] 1 | Homo sapiens | 7 | 17 |
| NPT1581 | Carbonyl reductase [NADPH] 1 | Homo sapiens | 7 | 17 |
| NPT1589 | Aldehyde reductase | Sus scrofa | 1 | 1 |
| NPT1588 | Estradiol 17-beta-dehydrogenase 2 | Homo sapiens | 16 | 23 |
| NPT1588 | Estradiol 17-beta-dehydrogenase 2 | Homo sapiens | 16 | 23 |
| NPT958 | Estradiol 17-beta-dehydrogenase 3 | Homo sapiens | 9 | 27 |
| NPT3718 | Malate dehydrogenase | Plasmodium falciparum | 2 | 2 |
| NPT3719 | Malate dehydrogenase cytoplasmic | Sus scrofa | 2 | 2 |
| NPT1770 | Alcohol dehydrogenase alpha chain | Homo sapiens | 3 | 3 |
| NPT4522 | Glucose-6-phosphate 1-dehydrogenase | Trypanosoma brucei | 2 | 4 |
| NPT5918 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic | Arabidopsis thaliana | 1 | 1 |
| NPT5919 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli | 1 | 1 |
| NPT5917 | 1-deoxyxylulose-5-phosphate reductoisomerase | Synechocystis sp. (strain PCC 6803 / Kazusa) | 1 | 1 |
| NPT151 | 15-hydroxyprostaglandin dehydrogenase [NAD+] | Homo sapiens | 296 | 406 |
| NPT710 | Aldose reductase-related protein 1 | Rattus norvegicus | 1 | 1 |
| NPT711 | Aldose reductase | Bos taurus | 13 | 23 |
| NPT711 | Aldose reductase | Bos taurus | 13 | 23 |
| NPT4734 | Dehydrogenase/reductase SDR family member 9 | Homo sapiens | 1 | 1 |
| NPT1347 | Alcohol dehydrogenase | Equus caballus | 14 | 16 |
| NPT5638 | Dehydrogenase/reductase SDR family member 9 | Rattus norvegicus | 1 | 2 |
| NPT149 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Homo sapiens | 290 | 470 |
| NPT149 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Homo sapiens | 290 | 470 |
| NPT149 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Homo sapiens | 290 | 470 |
| NPT366 | Quinone reductase 2 | Homo sapiens | 15 | 32 |
| NPT2817 | Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens | 9 | 31 |
| NPT6383 | Inosine-5'-monophosphate dehydrogenase 2 | Mus musculus | 7 | 7 |
| NPT68 | Aldose reductase | Rattus norvegicus | 176 | 224 |
| NPT1137 | 11-beta-hydroxysteroid dehydrogenase 1 | Homo sapiens | 31 | 65 |
| NPT1138 | 11-beta-hydroxysteroid dehydrogenase 2 | Homo sapiens | 19 | 41 |
| NPT861 | Isocitrate dehydrogenase [NADP] cytoplasmic | Homo sapiens | 305 | 378 |
| NPT590 | 3-alpha-hydroxysteroid dehydrogenase | Rattus norvegicus | 4 | 5 |
| NPT5046 | Inosine-5'-monophosphate dehydrogenase | Escherichia coli K-12 | 1 | 1 |
| NPT3727 | L-lactate dehydrogenase B chain | Homo sapiens | 2 | 4 |
| NPT900 | 3-keto-steroid reductase | Homo sapiens | 29 | 46 |
| NPT900 | 3-keto-steroid reductase | Homo sapiens | 29 | 46 |
| NPT905 | Glucose-6-phosphate 1-dehydrogenase | Homo sapiens | 20 | 26 |
| NPT906 | Testosterone 17-beta-dehydrogenase 3 | Rattus norvegicus | 3 | 4 |
| NPT4364 | 17-beta-hydroxysteroid-dehydrogenase | Cochliobolus lunatus | 1 | 2 |
| NPT41 | Aldose reductase | Homo sapiens | 119 | 165 |
| NPT2519 | HMG-CoA reductase | Mus musculus | 1 | 2 |
| NPT4284 | Photosystem Q(B) protein | Spinacia oleracea | 7 | 29 |
| NPT3506 | Aldo-keto reductase family 1 member C4 | Homo sapiens | 9 | 10 |
| NPT3506 | Aldo-keto reductase family 1 member C4 | Homo sapiens | 9 | 10 |
| NPT3506 | Aldo-keto reductase family 1 member C4 | Homo sapiens | 9 | 10 |
| NPT6196 | 6-phosphogluconate dehydrogenase, decarboxylating | Ovis aries | 1 | 1 |
| NPT5434 | 3-oxoacyl-(Acyl-carrier protein) reductase | Plasmodium falciparum (isolate 3D7) | 1 | 1 |
| NPT4762 | Inosine-5'-monophosphate dehydrogenase 1 | Homo sapiens | 2 | 13 |
| NPT5340 | Inosine-5'-monophosphate dehydrogenase (IMPDH) | Homo sapiens | 5 | 5 |
| NPT4259 | 11-beta-hydroxysteroid dehydrogenase 2 | Rattus norvegicus | 3 | 4 |
| NPT253 | HMG-CoA reductase | Homo sapiens | 10 | 59 |
| NPT1088 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Sus scrofa | 26 | 27 |
| NPT6071 | Alcohol dehydrogenase gamma chain | Homo sapiens | 2 | 2 |
| NPT642 | NADP-dependent malic enzyme, mitochondrial | Homo sapiens | 2 | 2 |
| NPT644 | L-lactate dehydrogenase A chain | Homo sapiens | 5 | 14 |
| NPT4242 | Aldose reductase | Mus musculus | 1 | 1 |
| NPT1270 | Aldo-keto reductase family 1 member B10 | Homo sapiens | 25 | 49 |
| NPT2981 | dTDP-4-dehydrorhamnose reductase | Mycobacterium tuberculosis | 1 | 1 |
| NPT6072 | Alcohol dehydrogenase class II | Homo sapiens | 2 | 2 |
| NPT6073 | Alcohol dehydrogenase class IV | Homo sapiens | 2 | 2 |
| NPT6070 | Alcohol dehydrogenase beta chain | Homo sapiens | 2 | 2 |