Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT561 | Organism | Tetrahymena pyriformis | Tetrahymena pyriformis | GI50 | = | 293156818.6 | nM | 10.1007/s00044-009-9166-z |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC324353 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.6923 | Remote Similarity | NPC294703 |
0.6667 | Remote Similarity | NPC219266 |
0.6429 | Remote Similarity | NPC52403 |
0.6207 | Remote Similarity | NPC256186 |
0.6207 | Remote Similarity | NPC23071 |
0.6207 | Remote Similarity | NPC245688 |
0.6207 | Remote Similarity | NPC199270 |
0.6154 | Remote Similarity | NPC311000 |
0.6071 | Remote Similarity | NPC299484 |
0.6071 | Remote Similarity | NPC88839 |
0.6071 | Remote Similarity | NPC110344 |
0.6 | Remote Similarity | NPC275462 |
0.6 | Remote Similarity | NPC213764 |
0.6 | Remote Similarity | NPC88887 |
0.6 | Remote Similarity | NPC232554 |
0.5926 | Remote Similarity | NPC236761 |
0.5862 | Remote Similarity | NPC39977 |
0.5806 | Remote Similarity | NPC560 |
0.5806 | Remote Similarity | NPC252154 |
0.5667 | Remote Similarity | NPC94144 |
0.5667 | Remote Similarity | NPC87529 |
0.5625 | Remote Similarity | NPC276332 |
0.5625 | Remote Similarity | NPC320326 |
0.5625 | Remote Similarity | NPC39869 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC324353 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.6154 | Remote Similarity | NPD8223 | Approved |
PubChem CID   | 13569 |
ChEMBL   | CHEMBL2260957 |
ZINC   |
Molecular Weight:   | 108.03 |
ALogP:   | -0.2688 |
MLogP:   | 1.68 |
XLogP:   | 0.982 |
# Rotatable Bonds:   | 5 |
Polar Surface Area:   | 20.23 |
# H-Bond Aceptor:   | 1 |
# H-Bond Donor:   | 1 |
# Rings:   | 0 |
# Heavy Atoms:   | 6 |