Organism ID | Organism Name | Taxonomy Level | Family | SuperKingdom | Isolation Part | Collection Location | Collection Time | Reference |
---|---|---|---|---|---|---|---|---|
NPO22810 | Streptomyces | Species | Streptomycetaceae | Bacteria | StreptomeDB* |
Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT32 | Organism | Mus musculus | Mus musculus | LD50 | = | 10 | mg/kg | 23489622 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC313420 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.6765 | Remote Similarity | NPC314510 |
0.6479 | Remote Similarity | NPC41429 |
0.6232 | Remote Similarity | NPC216415 |
0.6232 | Remote Similarity | NPC476537 |
0.619 | Remote Similarity | NPC193872 |
0.6143 | Remote Similarity | NPC329564 |
0.6143 | Remote Similarity | NPC327170 |
0.6094 | Remote Similarity | NPC80350 |
0.6 | Remote Similarity | NPC321468 |
0.6 | Remote Similarity | NPC320598 |
0.6 | Remote Similarity | NPC317143 |
0.6 | Remote Similarity | NPC327748 |
0.6 | Remote Similarity | NPC316826 |
0.5938 | Remote Similarity | NPC87359 |
0.5938 | Remote Similarity | NPC180402 |
0.5897 | Remote Similarity | NPC315897 |
0.5775 | Remote Similarity | NPC254541 |
0.5732 | Remote Similarity | NPC191774 |
0.5714 | Remote Similarity | NPC318260 |
0.5714 | Remote Similarity | NPC317147 |
0.5714 | Remote Similarity | NPC472579 |
0.5634 | Remote Similarity | NPC472578 |
0.5634 | Remote Similarity | NPC189301 |
0.5634 | Remote Similarity | NPC176164 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC313420 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.6618 | Remote Similarity | NPD1155 | Discontinued |
0.629 | Remote Similarity | NPD379 | Clinical (unspecified phase) |
0.5897 | Remote Similarity | NPD1825 | Clinical (unspecified phase) |
0.5882 | Remote Similarity | NPD1830 | Clinical (unspecified phase) |
0.5769 | Remote Similarity | NPD5386 | Phase 2 |
0.5765 | Remote Similarity | NPD4829 | Discontinued |
0.5732 | Remote Similarity | NPD4278 | Clinical (unspecified phase) |
0.5696 | Remote Similarity | NPD1147 | Phase 2 |
0.5692 | Remote Similarity | NPD362 | Phase 1 |
0.5667 | Remote Similarity | NPD9453 | Phase 3 |
0.5641 | Remote Similarity | NPD2702 | Phase 1 |
0.5641 | Remote Similarity | NPD2704 | Phase 3 |
0.56 | Remote Similarity | NPD1827 | Clinical (unspecified phase) |
0.56 | Remote Similarity | NPD1828 | Approved |
0.56 | Remote Similarity | NPD1829 | Clinical (unspecified phase) |
PubChem CID   | 160703 |
ChEMBL   | CHEMBL2392458 |
ZINC   |
Molecular Weight:   | 198.15 |
ALogP:   | -1.4578 |
MLogP:   | 1.9 |
XLogP:   | -0.512 |
# Rotatable Bonds:   | 7 |
Polar Surface Area:   | 108.48 |
# H-Bond Aceptor:   | 5 |
# H-Bond Donor:   | 4 |
# Rings:   | 1 |
# Heavy Atoms:   | 14 |