Target ID |
Target Type |
Target Name |
Target Organism |
Activity Type |
Activity Relation |
Value |
Unit |
Reference |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED50 |
= |
18.5 |
mg/kg |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
19.2 |
mg/kg |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
41.5 |
mg/kg |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
22.4 |
mg/kg |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
> |
7.9 |
mg/kg |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
11.7 |
mg/kg |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
IC50 |
= |
2500000 |
nM |
6161252 |
NPT1537 |
Protein Family |
Phosphodiesterase 4 |
Rattus norvegicus |
Ki |
= |
530000 |
nM |
6161252 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
1150000 |
nM |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
42.4 |
% |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
25.1 |
% |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
51.9 |
% |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
52.5 |
% |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
13 |
% |
6161252 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
0 |
% |
6161252 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
2.6 |
|
6161252 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
ED50 |
= |
37 |
umol/kg |
1527785 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
0.9 |
nM |
1527785 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
0.92 |
nM |
1527785 |
NPT5438 |
Protein Family |
Heart phosphodiesterase |
Bos taurus |
IC50 |
= |
92000 |
nM |
1527785 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
Activity |
= |
130 |
% |
1527785 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
Activity |
= |
170 |
% |
1527785 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
LD50 |
= |
1900 |
umol/kg |
1527785 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
47.2 |
mg/kg |
6134832 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
IC50 |
= |
6520 |
nM |
1331454 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
700 |
nM |
2258897 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
1310 |
nM |
2258897 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
940 |
nM |
2258897 |
NPT5099 |
Protein Family |
Phosphodiesterase 1 |
Homo sapiens |
IC50 |
= |
356000 |
nM |
9379444 |
NPT5439 |
Protein Family |
Phosphodiesterase 3 |
Homo sapiens |
IC50 |
= |
240000 |
nM |
9379444 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
IC50 |
= |
81000 |
nM |
9379444 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
EC50 |
= |
28000 |
nM |
9379444 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
EC20 |
= |
0.088 |
nM |
9379444 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Kd |
= |
29512.09 |
nM |
9379444 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
23000 |
nM |
1501234 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
9700 |
nM |
1501234 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8470 |
nM |
1501234 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
16000 |
nM |
1501234 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
25300 |
nM |
1501234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
2 |
% |
1501234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
5 |
% |
1501234 |
NPT5440 |
Individual Protein |
Phosphodiesterase 1B |
Bos taurus |
Inhibition |
= |
46 |
% |
8120866 |
NPT5441 |
Individual Protein |
Phosphodiesterase 1C |
Homo sapiens |
Inhibition |
= |
13 |
% |
8120866 |
NPT5442 |
Individual Protein |
Phosphodiesterase 2A |
Bos taurus |
Inhibition |
= |
0 |
% |
8120866 |
NPT5439 |
Protein Family |
Phosphodiesterase 3 |
Homo sapiens |
Inhibition |
= |
30 |
% |
8120866 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
Inhibition |
= |
26 |
% |
8120866 |
NPT273 |
Individual Protein |
Phosphodiesterase 5A |
Homo sapiens |
Inhibition |
= |
13 |
% |
8120866 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
IC50 |
= |
19000 |
nM |
8120866 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
9435909 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
17000 |
nM |
9435909 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
19000 |
nM |
9435909 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
9400 |
nM |
9435909 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
8230124 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
22000 |
nM |
8230124 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
41.5 |
mg/kg |
7108903 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
22.4 |
mg/kg |
7108903 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
309000 |
nM |
1969485 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
ED50 |
= |
140 |
mg/kg |
1969485 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8500 |
nM |
2795597 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
25000 |
nM |
2795597 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
3 |
|
2795597 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
EC50 |
= |
28200 |
nM |
1331453 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
EC15 |
= |
0.062 |
nM |
1331453 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
Ki |
= |
56800 |
nM |
1331453 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
9800 |
nM |
1331453 |
NPT4262 |
Individual Protein |
Adenosine A2a receptor |
Cavia porcellus |
Ki |
= |
16600 |
nM |
1331453 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED50 |
= |
23.4 |
mg/kg |
1331453 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED15 |
= |
20.2 |
mg kg-1 i.d. |
1331453 |
NPT4262 |
Individual Protein |
Adenosine A2a receptor |
Cavia porcellus |
Ki |
= |
13000 |
nM |
6279840 |
NPT5444 |
Protein Family |
Adenosine receptor |
Rattus norvegicus |
Ki |
= |
9000 |
nM |
6279840 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
20000 |
nM |
6279840 |
NPT5444 |
Protein Family |
Adenosine receptor |
Rattus norvegicus |
Ki |
= |
20000 |
nM |
6279840 |
NPT5444 |
Protein Family |
Adenosine receptor |
Rattus norvegicus |
Ki |
= |
2000 |
nM |
6279840 |
NPT5444 |
Protein Family |
Adenosine receptor |
Rattus norvegicus |
Ki |
= |
22000 |
nM |
6279840 |
NPT5444 |
Protein Family |
Adenosine receptor |
Rattus norvegicus |
Ki |
= |
4500 |
nM |
6279840 |
NPT5444 |
Protein Family |
Adenosine receptor |
Rattus norvegicus |
Ki |
= |
150 |
nM |
6279840 |
NPT5438 |
Protein Family |
Heart phosphodiesterase |
Bos taurus |
IC50 |
= |
412000 |
nM |
6265639 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
23000 |
nM |
1992150 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
16000 |
nM |
1992150 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
3806581 |
NPT4262 |
Individual Protein |
Adenosine A2a receptor |
Cavia porcellus |
Ki |
= |
14000 |
nM |
3806581 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
8500 |
nM |
8071944 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
25000 |
nM |
8071944 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
3 |
|
8071944 |
NPT1774 |
Protein Family |
Sodium channel alpha subunits; brain (Types I, II, III) |
Homo sapiens |
Inhibition |
= |
6.9 |
% |
2579237 |
NPT1774 |
Protein Family |
Sodium channel alpha subunits; brain (Types I, II, III) |
Homo sapiens |
Inhibition |
= |
7 |
% |
2579237 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
13000 |
nM |
2724296 |
NPT2812 |
Protein Family |
Adenosine A2 receptor |
Homo sapiens |
Ki |
= |
14000 |
nM |
2724296 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8700 |
nM |
2724296 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
17000 |
nM |
2724296 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
IC50 |
= |
28000 |
nM |
6090665 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
IC50 |
= |
42000 |
nM |
6090665 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
Inhibition |
= |
39 |
% |
9873649 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
Inhibition |
= |
27 |
% |
9873649 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
3800 |
nM |
10737748 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Inhibition |
= |
2100 |
% |
10737748 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
10737748 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
IC50 |
> |
10000 |
nM |
3361572 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
IC50 |
> |
10000 |
nM |
3361572 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
IC50 |
= |
10000 |
nM |
3361572 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
IC50 |
= |
3000 |
nM |
3361572 |
NPT5222 |
Individual Protein |
Phosphodiesterase 3B |
Bos taurus |
IC50 |
= |
90000 |
nM |
6279846 |
NPT5222 |
Individual Protein |
Phosphodiesterase 3B |
Bos taurus |
IC50 |
= |
210000 |
nM |
6279846 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
85000 |
nM |
6279846 |
NPT5222 |
Individual Protein |
Phosphodiesterase 3B |
Bos taurus |
Ki |
= |
77000 |
nM |
6279846 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
180000 |
nM |
6279846 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
110000 |
nM |
6279846 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Kb |
= |
8700 |
nM |
12139454 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Kb |
= |
13700 |
nM |
12139454 |
NPT5445 |
Individual Protein |
Adenosine A2b receptor |
Mus musculus |
Kb |
= |
16000 |
nM |
12139454 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8500 |
nM |
7932565 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
25000 |
nM |
7932565 |
NPT1760 |
Individual Protein |
Adenosine A3 receptor |
Rattus norvegicus |
Inhibition |
= |
23.1 |
% |
7932565 |
NPT2555 |
Others |
Adenosine receptors; A1 & A3 |
Rattus norvegicus |
Ratio |
> |
10 |
|
7932565 |
NPT2687 |
Others |
Adenosine receptor A2a and A3 |
Rattus norvegicus |
Ratio |
> |
4 |
|
7932565 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
8182711 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
19000 |
nM |
8182711 |
NPT605 |
Organism |
Homo sapiens |
Homo sapiens |
IC50 |
= |
335000 |
nM |
2415706 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
ED50 |
= |
140 |
mg/kg |
2415706 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8500 |
nM |
2342066 |
NPT5438 |
Protein Family |
Heart phosphodiesterase |
Bos taurus |
IC50 |
= |
286000 |
nM |
6265635 |
NPT5438 |
Protein Family |
Heart phosphodiesterase |
Bos taurus |
IC50 |
= |
412000 |
nM |
6265635 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8500 |
nM |
1738138 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ratio |
= |
25000 |
nM |
1738138 |
NPT4749 |
Others |
Adenosine receptors; A1 & A2 |
Rattus norvegicus |
Ratio |
= |
3 |
|
1738138 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
EC50 |
= |
28200 |
nM |
8496906 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
EC15 |
= |
0.062 |
nM |
8496906 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED50 |
= |
23.4 |
mg/kg |
8496906 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED15 |
= |
20.2 |
mg/kg |
8496906 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
Ki |
= |
56800 |
nM |
8496906 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
9800 |
nM |
8496906 |
NPT2812 |
Protein Family |
Adenosine A2 receptor |
Homo sapiens |
Ki |
= |
16600 |
nM |
8496906 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
23000 |
nM |
1548682 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
16000 |
nM |
1548682 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8470 |
nM |
1548682 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
13000 |
nM |
1548682 |
NPT2 |
Others |
Unspecified |
|
Kb |
= |
4800 |
nM |
1548682 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
25300 |
nM |
1548682 |
NPT2 |
Others |
Unspecified |
|
Kb |
= |
5700 |
nM |
1548682 |
NPT4749 |
Others |
Adenosine receptors; A1 & A2 |
Rattus norvegicus |
Ratio |
= |
0.7 |
|
1548682 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
9070 |
nM |
12014951 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
6920 |
nM |
12014951 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
6700 |
nM |
12014951 |
NPT3054 |
Individual Protein |
Adenosine A2b receptor |
Rattus norvegicus |
Ki |
= |
15100 |
nM |
12014951 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
0.46 |
|
12014951 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
0.44 |
|
12014951 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
23000 |
nM |
8355252 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8470 |
nM |
8355252 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
16000 |
nM |
8355252 |
NPT4757 |
Others |
Adenosine receptors; A1 & A2 |
Homo sapiens |
Ratio |
= |
0.7 |
|
8355252 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
IC50 |
= |
3.02E+12 |
nM |
2991519 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
IC50 |
= |
1.41E+13 |
nM |
2991519 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
IC50 |
= |
12700 |
nM |
2991519 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
IC50 |
= |
2430 |
nM |
2991519 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
2213834 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
25000 |
nM |
2213834 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
17000 |
nM |
2213834 |
NPT5099 |
Protein Family |
Phosphodiesterase 1 |
Homo sapiens |
IC50 |
= |
320000 |
nM |
2985781 |
NPT5100 |
Individual Protein |
Phosphodiesterase 2A |
Homo sapiens |
IC50 |
= |
210000 |
nM |
2985781 |
NPT5439 |
Protein Family |
Phosphodiesterase 3 |
Homo sapiens |
IC50 |
= |
360000 |
nM |
2985781 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
0.9 |
nM |
6319701 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED50 |
= |
43 |
nM |
6319701 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
2984420 |
NPT4262 |
Individual Protein |
Adenosine A2a receptor |
Cavia porcellus |
Ki |
= |
14000 |
nM |
2984420 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1 |
|
2984420 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
8410976 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
8000 |
nM |
8410976 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED50 |
= |
70.8 |
nM |
3965705 |
NPT2560 |
Protein Family |
Phosphodiesterase 4 |
Homo sapiens |
IC50 |
= |
1780000 |
nM |
3965705 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8470 |
nM |
2754711 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
25300 |
nM |
2754711 |
NPT4749 |
Others |
Adenosine receptors; A1 & A2 |
Rattus norvegicus |
Ratio |
= |
2.99 |
|
2754711 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
6000 |
nM |
2002461 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
9200 |
nM |
2002461 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
25000 |
nM |
2002461 |
NPT4749 |
Others |
Adenosine receptors; A1 & A2 |
Rattus norvegicus |
Ratio |
= |
2.7 |
|
2002461 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
3800 |
nM |
15214785 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6200 |
nM |
15214785 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
21000 |
nM |
15214785 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
15214785 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
106 |
% |
10411473 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
3.75 |
|
3172125 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
66 |
% |
3172125 |
NPT2811 |
Individual Protein |
Adenosine A1 receptor |
Cavia porcellus |
Ki |
= |
23000 |
nM |
1613758 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
16000 |
nM |
1613758 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
13000 |
nM |
1613758 |
NPT5446 |
Individual Protein |
Brain adenylate cyclase 1 |
Homo sapiens |
Kb |
= |
14000 |
nM |
1613758 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8470 |
nM |
1613758 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
25300 |
nM |
1613758 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
3800 |
nM |
10956220 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
21000 |
nM |
10956220 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
10956220 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
3172141 |
NPT2812 |
Protein Family |
Adenosine A2 receptor |
Homo sapiens |
Ki |
= |
14000 |
nM |
3172141 |
NPT2554 |
Protein Family |
Adenosine A2 receptor |
Rattus norvegicus |
Ki |
= |
4800 |
nM |
3172141 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
286000 |
nM |
6273558 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
412000 |
nM |
6273558 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
7400 |
nM |
3172141 |
NPT2812 |
Protein Family |
Adenosine A2 receptor |
Homo sapiens |
Ki |
= |
13800 |
nM |
3172141 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
77000 |
nM |
6279842 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
180000 |
nM |
6279842 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
150000 |
nM |
6279842 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
90000 |
nM |
6279842 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
210000 |
nM |
6279842 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
190000 |
nM |
6279842 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
IC50 |
= |
6520 |
nM |
1479586 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Inhibition |
= |
60 |
% |
11063618 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
MIC |
= |
30 |
ug/ml |
11063618 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
IC50 |
= |
20000 |
nM |
3806606 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
100000 |
nM |
6276544 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
190000 |
nM |
6276544 |
NPT5447 |
Individual Protein |
Phosphodiesterase 1A |
Bos taurus |
IC50 |
= |
500000 |
nM |
2547071 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Kd |
= |
12000 |
nM |
15771445 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
7059 |
nM |
15664822 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
0.6 |
nM |
15664822 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
0.6 |
nM |
15664822 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
14 |
nM |
15664822 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
9070 |
nM |
16250640 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
3800 |
nM |
16335918 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
21000 |
nM |
16335918 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
16335918 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6200 |
nM |
16335918 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
7900 |
nM |
16335918 |
NPT5448 |
Others |
Adenosine receptors; A1 & A3 |
Homo sapiens |
Ratio Ki |
= |
0.07 |
|
16335918 |
NPT5448 |
Others |
Adenosine receptors; A1 & A3 |
Homo sapiens |
Ratio Ki |
= |
0.092 |
|
16335918 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
9070 |
nM |
16759111 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6920 |
nM |
16759111 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
6700 |
nM |
16759111 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
22300 |
nM |
16759111 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
21000 |
nM |
16789747 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
3800 |
nM |
16789747 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
7900 |
nM |
16789747 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6200 |
nM |
16789747 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
16789747 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
17665891 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6200 |
nM |
17665891 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
7900 |
nM |
17665891 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
176 |
|
17533133 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
114 |
|
17533133 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
77 |
|
17533133 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
54 |
|
17533133 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
159 |
|
17533133 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
64 |
|
17533133 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
42 |
|
17533133 |
NPT1726 |
Organism |
Vibrio harveyi |
Vibrio harveyi |
Activity |
= |
15 |
|
17533133 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
8500 |
nM |
10757709 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
39 |
% |
18686943 |
NPT802 |
Individual Protein |
Alkaline phosphatase, tissue-nonspecific isozyme |
Homo sapiens |
Ki |
= |
82000 |
nM |
19038545 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
19301821 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
3800 |
nM |
19301821 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
21000 |
nM |
19301821 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6200 |
nM |
19301821 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
7900 |
nM |
19301821 |
NPT31 |
Individual Protein |
Cyclooxygenase-2 |
Homo sapiens |
Inhibition |
< |
30 |
% |
12444669 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
26000 |
nM |
9514015 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
22000 |
nM |
9514015 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
565000 |
nM |
9514015 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
21000 |
nM |
18468446 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
86000 |
nM |
18468446 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6200 |
nM |
18468446 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
7900 |
nM |
18468446 |
NPT5049 |
Individual Protein |
Adenosine A1 receptor |
Bos taurus |
Ki |
= |
3800 |
nM |
18468446 |
NPT613 |
Individual Protein |
Solute carrier family 22 member 1 |
Homo sapiens |
Inhibition |
= |
-4.4 |
% |
18788725 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6200 |
nM |
19569717 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
4200 |
nM |
19569717 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
7850 |
nM |
19569717 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
52300 |
nM |
19569717 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8500 |
nM |
19569717 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
25000 |
nM |
19569717 |
NPT3054 |
Individual Protein |
Adenosine A2b receptor |
Rattus norvegicus |
Ki |
= |
15100 |
nM |
19569717 |
NPT1760 |
Individual Protein |
Adenosine A3 receptor |
Rattus norvegicus |
Ki |
= |
100000 |
nM |
19569717 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
550000 |
nM |
20004571 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
400000 |
nM |
20004571 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
430000 |
nM |
20004571 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
300000 |
nM |
20004571 |
NPT1149 |
Individual Protein |
Phospholipase A-2-activating protein |
Homo sapiens |
IC50 |
> |
5000 |
nM |
20031422 |
NPT802 |
Individual Protein |
Alkaline phosphatase, tissue-nonspecific isozyme |
Homo sapiens |
IC50 |
> |
5000 |
nM |
20031422 |
NPT801 |
Individual Protein |
Intestinal alkaline phosphatase |
Homo sapiens |
IC50 |
> |
5000 |
nM |
20031422 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
6700 |
nM |
20188574 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
22300 |
nM |
20188574 |
NPT1760 |
Individual Protein |
Adenosine A3 receptor |
Rattus norvegicus |
Ki |
= |
85000 |
nM |
20188574 |
NPT3054 |
Individual Protein |
Adenosine A2b receptor |
Rattus norvegicus |
Ki |
= |
15100 |
nM |
20188574 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
9070 |
nM |
20188574 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
22000 |
nM |
20188574 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
20188574 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6770 |
nM |
20188574 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
10100 |
nM |
20202853 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
18500 |
nM |
20202853 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
2700 |
nM |
20202853 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
85100 |
nM |
20202853 |
NPT605 |
Organism |
Homo sapiens |
Homo sapiens |
Activity |
= |
1 |
% |
20022146 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
9070 |
nM |
20537438 |
NPT312 |
Organism |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Potency |
= |
7079.5 |
nM |
PubChem BioAssay data set |
NPT211 |
Individual Protein |
Hypoxia-inducible factor 1 alpha |
Homo sapiens |
Potency |
= |
3162.3 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
= |
18356.4 |
nM |
PubChem BioAssay data set |
NPT53 |
Individual Protein |
4'-phosphopantetheinyl transferase ffp |
Bacillus subtilis |
Potency |
= |
56234.1 |
nM |
PubChem BioAssay data set |
NPT583 |
Individual Protein |
Inositol monophosphatase 1 |
Rattus norvegicus |
Potency |
= |
7943.3 |
nM |
PubChem BioAssay data set |
NPT150 |
Individual Protein |
Anthrax lethal factor |
Bacillus anthracis |
Potency |
= |
794.3 |
nM |
PubChem BioAssay data set |
NPT347 |
Cell Line |
Lymphoblastoid cells |
Homo sapiens |
Potency |
= |
39810.7 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
1995.3 |
nM |
PubChem BioAssay data set |
NPT5 |
Individual Protein |
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 |
Homo sapiens |
Potency |
|
3358.7 |
nM |
PubChem BioAssay data set |
NPT5 |
Individual Protein |
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 |
Homo sapiens |
Potency |
|
281.8 |
nM |
PubChem BioAssay data set |
NPT62 |
Individual Protein |
6-phospho-1-fructokinase |
Trypanosoma brucei |
Potency |
|
756.9 |
nM |
PubChem BioAssay data set |
NPT63 |
Individual Protein |
Bromodomain adjacent to zinc finger domain protein 2B |
Homo sapiens |
Potency |
|
2511.9 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
6513.1 |
nM |
PubChem BioAssay data set |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
> |
10000 |
nM |
21661720 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Kd |
= |
3162.28 |
nM |
21661720 |
NPT2 |
Others |
Unspecified |
|
FC |
= |
-1.8 |
|
21661720 |
NPT2 |
Others |
Unspecified |
|
FC |
= |
0 |
|
21661720 |
NPT2 |
Others |
Unspecified |
|
FC |
= |
0.1 |
|
21661720 |
NPT2 |
Others |
Unspecified |
|
FC |
= |
-0.1 |
|
21661720 |
NPT2 |
Others |
Unspecified |
|
FC |
= |
-0.4 |
|
21661720 |
NPT7 |
Individual Protein |
Thioredoxin reductase 1, cytoplasmic |
Rattus norvegicus |
Potency |
|
14125.4 |
nM |
PubChem BioAssay data set |
NPT71 |
Cell Line |
HEK293 |
Homo sapiens |
Potency |
|
517.1 |
nM |
PubChem BioAssay data set |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
IC50 |
= |
17104 |
nM |
DrugMatrix in vitro pharmacology data |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
9977 |
nM |
DrugMatrix in vitro pharmacology data |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
IC50 |
= |
12007 |
nM |
DrugMatrix in vitro pharmacology data |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
6741 |
nM |
DrugMatrix in vitro pharmacology data |
NPT367 |
Cell Line |
MDA-N |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT368 |
Cell Line |
SN12C |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT369 |
Cell Line |
ACHN |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT370 |
Cell Line |
NCI-H23 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT371 |
Cell Line |
UO-31 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT116 |
Cell Line |
HL-60 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT372 |
Cell Line |
HOP-92 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT90 |
Cell Line |
DU-145 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT374 |
Cell Line |
SF-539 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT373 |
Cell Line |
SK-MEL-5 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT375 |
Cell Line |
Malme-3M |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT111 |
Cell Line |
K562 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT377 |
Cell Line |
OVCAR-3 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT112 |
Cell Line |
MOLT-4 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT379 |
Cell Line |
HOP-62 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT378 |
Cell Line |
NCI/ADR-RES |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT381 |
Cell Line |
OVCAR-8 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT380 |
Cell Line |
U-251 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT382 |
Cell Line |
OVCAR-5 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT383 |
Cell Line |
SNB-19 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT82 |
Cell Line |
MDA-MB-231 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT385 |
Cell Line |
SR |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT384 |
Cell Line |
TK-10 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT323 |
Cell Line |
SW-620 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT455 |
Cell Line |
NCI-H522 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT386 |
Cell Line |
KM12 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT387 |
Cell Line |
M14 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT445 |
Individual Protein |
Peripheral myelin protein 22 |
Rattus norvegicus |
Potency |
|
2.9 |
nM |
PubChem BioAssay data set |
NPT388 |
Cell Line |
NCI-H322M |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT389 |
Cell Line |
RPMI-8226 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT390 |
Cell Line |
LOX IMVI |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT147 |
Cell Line |
SK-MEL-2 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT391 |
Cell Line |
HCC 2998 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT81 |
Cell Line |
A549 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT392 |
Cell Line |
SNB-75 |
Homo sapiens |
GI50 |
|
91201.08 |
nM |
PubChem BioAssay data set |
NPT393 |
Cell Line |
HCT-116 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT148 |
Cell Line |
HCT-15 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT394 |
Cell Line |
EKVX |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT395 |
Cell Line |
SF-268 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT306 |
Cell Line |
PC-3 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT396 |
Cell Line |
T47D |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT397 |
Cell Line |
NCI-H460 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT308 |
Cell Line |
CAKI-1 |
Homo sapiens |
GI50 |
|
22908.68 |
nM |
PubChem BioAssay data set |
NPT458 |
Cell Line |
IGROV-1 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT399 |
Cell Line |
SF-295 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT401 |
Cell Line |
786-0 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT402 |
Cell Line |
Hs-578T |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT403 |
Cell Line |
UACC-257 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT404 |
Cell Line |
CCRF-CEM |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT405 |
Cell Line |
NCI-H226 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT170 |
Cell Line |
SK-MEL-28 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT407 |
Cell Line |
COLO 205 |
Homo sapiens |
GI50 |
|
100000 |
nM |
PubChem BioAssay data set |
NPT433 |
Subcellular |
Liver microsomes |
Homo sapiens |
Activity |
= |
0 |
nmol |
22931300 |
NPT10 |
Individual Protein |
Geminin |
Homo sapiens |
Potency |
|
1258.9 |
nM |
PubChem BioAssay data set |
NPT103 |
Individual Protein |
Nuclear receptor ROR-gamma |
Homo sapiens |
Potency |
|
42163.2 |
nM |
PubChem BioAssay data set |
NPT1417 |
Individual Protein |
Transcriptional regulator ERG |
Homo sapiens |
Potency |
|
7079.5 |
nM |
PubChem BioAssay data set |
NPT622 |
Individual Protein |
Solute carrier organic anion transporter family member 2B1 |
Homo sapiens |
Inhibition |
= |
-25.5 |
% |
22541068 |
NPT72 |
Individual Protein |
Solute carrier organic anion transporter family member 1B3 |
Homo sapiens |
Inhibition |
= |
2.5 |
% |
22541068 |
NPT73 |
Individual Protein |
Solute carrier organic anion transporter family member 1B1 |
Homo sapiens |
Inhibition |
= |
0.8 |
% |
22541068 |
NPT5449 |
Individual Protein |
PDE7B protein |
Bos taurus |
Ratio |
= |
1 |
|
10.1007/s00044-008-9125-0 |
NPT5449 |
Individual Protein |
PDE7B protein |
Bos taurus |
IC50 |
= |
1720000 |
nM |
10.1007/s00044-008-9125-0 |
NPT2 |
Others |
Unspecified |
|
Potency |
|
9441.1 |
nM |
PubChem BioAssay data set |
NPT160 |
Individual Protein |
TAR DNA-binding protein 43 |
Homo sapiens |
Potency |
|
11220.2 |
nM |
PubChem BioAssay data set |
NPT861 |
Individual Protein |
Isocitrate dehydrogenase [NADP] cytoplasmic |
Homo sapiens |
Potency |
|
20596.2 |
nM |
PubChem BioAssay data set |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
22300 |
nM |
23200243 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
29400 |
nM |
23200243 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
1700 |
nM |
23200243 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
2030 |
nM |
23200243 |
NPT73 |
Individual Protein |
Solute carrier organic anion transporter family member 1B1 |
Homo sapiens |
Inhibition |
= |
90.11 |
% |
23571415 |
NPT72 |
Individual Protein |
Solute carrier organic anion transporter family member 1B3 |
Homo sapiens |
Inhibition |
= |
72.46 |
% |
23571415 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
Ki |
= |
22300 |
nM |
24139167 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
22000 |
nM |
24139167 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
6700 |
nM |
24139167 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
14000 |
nM |
24139167 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6770 |
nM |
24139167 |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
9070 |
nM |
24139167 |
NPT169 |
Cell Line |
B16-F10 |
Mus musculus |
Activity |
= |
127.6 |
% |
24433966 |
NPT169 |
Cell Line |
B16-F10 |
Mus musculus |
Activity |
= |
131.7 |
% |
24433966 |
NPT169 |
Cell Line |
B16-F10 |
Mus musculus |
Activity |
= |
166.8 |
% |
24433966 |
NPT169 |
Cell Line |
B16-F10 |
Mus musculus |
Activity |
= |
95.5 |
% |
24433966 |
NPT169 |
Cell Line |
B16-F10 |
Mus musculus |
Activity |
= |
94.4 |
% |
24433966 |
NPT169 |
Cell Line |
B16-F10 |
Mus musculus |
Activity |
= |
91.4 |
% |
24433966 |
NPT2 |
Others |
Unspecified |
|
ED50 |
= |
2.09 |
umol/ml |
24445313 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Survival |
= |
100 |
% |
24556147 |
NPT444 |
Individual Protein |
Ubiquitin carboxyl-terminal hydrolase 1 |
Homo sapiens |
Potency |
|
1258.9 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
1.1 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
76958.8 |
nM |
PubChem BioAssay data set |
NPT153 |
Individual Protein |
Androgen Receptor |
Homo sapiens |
Potency |
|
1.7 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
18833.6 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
62475.4 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
197.6 |
nM |
PubChem BioAssay data set |
NPT152 |
Individual Protein |
Nuclear factor erythroid 2-related factor 2 |
Homo sapiens |
Potency |
|
68589.6 |
nM |
PubChem BioAssay data set |
NPT104 |
Individual Protein |
Cerebroside-sulfatase |
Homo sapiens |
Potency |
|
37933 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
26603.2 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
21872.4 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
10682.2 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
29849.3 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
9901.7 |
nM |
PubChem BioAssay data set |
NPT11 |
Individual Protein |
Guanine nucleotide-binding protein G(s), subunit alpha |
Homo sapiens |
Potency |
|
11220.2 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
53 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
5.3 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
24658.6 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
30637.9 |
nM |
PubChem BioAssay data set |
NPT1446 |
Individual Protein |
PI3-kinase p110-delta subunit |
Homo sapiens |
IC50 |
= |
75000 |
nM |
10.1039/C2MD20044A |
NPT1444 |
Individual Protein |
PI3-kinase p110-alpha subunit |
Homo sapiens |
IC50 |
= |
300000 |
nM |
10.1039/C2MD20044A |
NPT3376 |
Individual Protein |
PI3-kinase p110-beta subunit |
Homo sapiens |
IC50 |
= |
800000 |
nM |
10.1039/C2MD20044A |
NPT1445 |
Individual Protein |
PI3-kinase p110-gamma subunit |
Homo sapiens |
IC50 |
= |
800000 |
nM |
10.1039/C2MD20044A |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
515000 |
nM |
229222 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
1475000 |
nM |
229222 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
5 |
% |
229222 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
51 |
% |
85712 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
50 |
% |
85712 |
NPT2 |
Others |
Unspecified |
|
EC50 |
= |
144000 |
nM |
24681028 |
NPT1316 |
Individual Protein |
Adenosine A2a receptor |
Rattus norvegicus |
Ki |
= |
25000 |
nM |
24164628 |
NPT1315 |
Individual Protein |
Adenosine A1 receptor |
Rattus norvegicus |
Ki |
= |
8500 |
nM |
24164628 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
170.7 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
91.4 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
204 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
131.7 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
183.2 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
94.4 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
127.6 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
95.5 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
166.8 |
% |
24853321 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
19900 |
nM |
25462283 |
NPT1445 |
Individual Protein |
PI3-kinase p110-gamma subunit |
Homo sapiens |
IC50 |
= |
2904000 |
nM |
25050878 |
NPT2 |
Others |
Unspecified |
|
AC50 |
|
22387.2 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
27906.7 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
2683.2 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
13800.6 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
841.3 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
21689.9 |
nM |
PubChem BioAssay data set |
NPT4059 |
Individual Protein |
Adenosine A2b receptor |
Homo sapiens |
Ki |
= |
9070 |
nM |
26824742 |
NPT216 |
Individual Protein |
Adenosine A1 receptor |
Homo sapiens |
Ki |
= |
6770 |
nM |
10.1039/C5MD00573F |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
Ki |
= |
1710 |
nM |
10.1039/C5MD00573F |
NPT5454 |
Individual Protein |
Transmembrane domain-containing protein TMIGD3 |
Homo sapiens |
Ki |
= |
86400 |
nM |
10.1039/C5MD00573F |