Organism ID | Organism Name | Taxonomy Level | Family | SuperKingdom | Isolation Part | Collection Location | Collection Time | Reference |
---|---|---|---|---|---|---|---|---|
NPO13661 | Tripterygium wilfordii | Species | Celastraceae | Eukaryota | TCMID* |
Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT927 | Cell Line | PBMC | Homo sapiens | Inhibition | = | 13.3 | % | 10579865 |
NPT927 | Cell Line | PBMC | Homo sapiens | Inhibition | = | 15.4 | % | 10579865 |
NPT927 | Cell Line | PBMC | Homo sapiens | Inhibition | = | 37.9 | % | 10579865 |
NPT927 | Cell Line | PBMC | Homo sapiens | Inhibition | = | -52.2 | % | 10579865 |
NPT927 | Cell Line | PBMC | Homo sapiens | Inhibition | = | 64.5 | % | 10579865 |
NPT927 | Cell Line | PBMC | Homo sapiens | Inhibition | = | 42.3 | % | 10579865 |
NPT1872 | Cell Line | Bcap37 | Homo sapiens | IC50 | > | 100000 | nM | 27133593 |
NPT2 | Others | Unspecified | IC50 | > | 100000 | nM | 27133593 | |
NPT65 | Cell Line | HepG2 | Homo sapiens | IC50 | = | 43730 | nM | 27133593 |
NPT75 | Cell Line | U251 | Homo sapiens | IC50 | > | 100000 | nM | 27133593 |
NPT83 | Cell Line | MCF7 | Homo sapiens | IC50 | > | 100000 | nM | 27133593 |
NPT81 | Cell Line | A549 | Homo sapiens | IC50 | = | 32840 | nM | 27133593 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC215419 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.9623 | High Similarity | NPC265513 |
0.9266 | High Similarity | NPC93287 |
0.9091 | High Similarity | NPC470253 |
0.9009 | High Similarity | NPC471721 |
0.9 | High Similarity | NPC280789 |
0.8839 | High Similarity | NPC130591 |
0.8839 | High Similarity | NPC234637 |
0.8796 | High Similarity | NPC471186 |
0.875 | High Similarity | NPC471481 |
0.8707 | High Similarity | NPC202015 |
0.8707 | High Similarity | NPC476645 |
0.8696 | High Similarity | NPC80605 |
0.8696 | High Similarity | NPC323440 |
0.8696 | High Similarity | NPC222968 |
0.8661 | High Similarity | NPC218855 |
0.8611 | High Similarity | NPC247976 |
0.8584 | High Similarity | NPC143768 |
0.8559 | High Similarity | NPC476234 |
0.85 | High Similarity | NPC85511 |
0.8487 | Intermediate Similarity | NPC269923 |
0.8487 | Intermediate Similarity | NPC167323 |
0.8475 | Intermediate Similarity | NPC472680 |
0.8475 | Intermediate Similarity | NPC472679 |
0.8462 | Intermediate Similarity | NPC318173 |
0.8426 | Intermediate Similarity | NPC109514 |
0.8403 | Intermediate Similarity | NPC472981 |
0.8396 | Intermediate Similarity | NPC219573 |
0.8396 | Intermediate Similarity | NPC185208 |
0.8393 | Intermediate Similarity | NPC470252 |
0.8378 | Intermediate Similarity | NPC100767 |
0.8378 | Intermediate Similarity | NPC94751 |
0.8378 | Intermediate Similarity | NPC142326 |
0.8348 | Intermediate Similarity | NPC196673 |
0.8347 | Intermediate Similarity | NPC472681 |
0.8333 | Intermediate Similarity | NPC471188 |
0.8333 | Intermediate Similarity | NPC471189 |
0.8318 | Intermediate Similarity | NPC239185 |
0.8305 | Intermediate Similarity | NPC472698 |
0.8305 | Intermediate Similarity | NPC472697 |
0.8304 | Intermediate Similarity | NPC112903 |
0.8291 | Intermediate Similarity | NPC469843 |
0.8257 | Intermediate Similarity | NPC136810 |
0.8257 | Intermediate Similarity | NPC476993 |
0.8257 | Intermediate Similarity | NPC128248 |
0.8257 | Intermediate Similarity | NPC133809 |
0.8241 | Intermediate Similarity | NPC134882 |
0.8214 | Intermediate Similarity | NPC83409 |
0.8214 | Intermediate Similarity | NPC185763 |
0.8197 | Intermediate Similarity | NPC328107 |
0.819 | Intermediate Similarity | NPC326664 |
0.819 | Intermediate Similarity | NPC294458 |
0.8175 | Intermediate Similarity | NPC471334 |
0.8174 | Intermediate Similarity | NPC292834 |
0.8148 | Intermediate Similarity | NPC265220 |
0.8145 | Intermediate Similarity | NPC470648 |
0.8113 | Intermediate Similarity | NPC323420 |
0.8091 | Intermediate Similarity | NPC225079 |
0.808 | Intermediate Similarity | NPC316553 |
0.808 | Intermediate Similarity | NPC51448 |
0.808 | Intermediate Similarity | NPC472678 |
0.808 | Intermediate Similarity | NPC115797 |
0.808 | Intermediate Similarity | NPC478165 |
0.808 | Intermediate Similarity | NPC478162 |
0.8073 | Intermediate Similarity | NPC75724 |
0.8067 | Intermediate Similarity | NPC268930 |
0.8067 | Intermediate Similarity | NPC61651 |
0.8036 | Intermediate Similarity | NPC329282 |
0.8019 | Intermediate Similarity | NPC220596 |
0.8017 | Intermediate Similarity | NPC186128 |
0.8 | Intermediate Similarity | NPC474106 |
0.8 | Intermediate Similarity | NPC221825 |
0.8 | Intermediate Similarity | NPC54647 |
0.7984 | Intermediate Similarity | NPC472694 |
0.7984 | Intermediate Similarity | NPC472693 |
0.7983 | Intermediate Similarity | NPC158157 |
0.7965 | Intermediate Similarity | NPC172483 |
0.7963 | Intermediate Similarity | NPC260233 |
0.7946 | Intermediate Similarity | NPC472691 |
0.7946 | Intermediate Similarity | NPC471829 |
0.7946 | Intermediate Similarity | NPC474866 |
0.7946 | Intermediate Similarity | NPC475939 |
0.7946 | Intermediate Similarity | NPC329556 |
0.7944 | Intermediate Similarity | NPC153885 |
0.7944 | Intermediate Similarity | NPC59677 |
0.7931 | Intermediate Similarity | NPC474057 |
0.792 | Intermediate Similarity | NPC328997 |
0.792 | Intermediate Similarity | NPC294050 |
0.7909 | Intermediate Similarity | NPC49994 |
0.7903 | Intermediate Similarity | NPC318067 |
0.7899 | Intermediate Similarity | NPC260886 |
0.787 | Intermediate Similarity | NPC289883 |
0.787 | Intermediate Similarity | NPC238219 |
0.7857 | Intermediate Similarity | NPC146239 |
0.785 | Intermediate Similarity | NPC133461 |
0.7846 | Intermediate Similarity | NPC477139 |
0.784 | Intermediate Similarity | NPC478108 |
0.7833 | Intermediate Similarity | NPC212891 |
0.783 | Intermediate Similarity | NPC298115 |
0.7829 | Intermediate Similarity | NPC471851 |
0.7818 | Intermediate Similarity | NPC226041 |
0.7818 | Intermediate Similarity | NPC324602 |
0.7807 | Intermediate Similarity | NPC134120 |
0.7788 | Intermediate Similarity | NPC274443 |
0.7786 | Intermediate Similarity | NPC474659 |
0.7778 | Intermediate Similarity | NPC155232 |
0.7778 | Intermediate Similarity | NPC475002 |
0.7778 | Intermediate Similarity | NPC95126 |
0.776 | Intermediate Similarity | NPC325740 |
0.776 | Intermediate Similarity | NPC51079 |
0.7752 | Intermediate Similarity | NPC472692 |
0.7752 | Intermediate Similarity | NPC472682 |
0.775 | Intermediate Similarity | NPC9274 |
0.7744 | Intermediate Similarity | NPC475957 |
0.7739 | Intermediate Similarity | NPC37914 |
0.7739 | Intermediate Similarity | NPC244933 |
0.7739 | Intermediate Similarity | NPC85560 |
0.7739 | Intermediate Similarity | NPC472699 |
0.7739 | Intermediate Similarity | NPC472700 |
0.7731 | Intermediate Similarity | NPC67377 |
0.7724 | Intermediate Similarity | NPC238861 |
0.7724 | Intermediate Similarity | NPC77000 |
0.7724 | Intermediate Similarity | NPC133389 |
0.7724 | Intermediate Similarity | NPC476225 |
0.7724 | Intermediate Similarity | NPC183339 |
0.7724 | Intermediate Similarity | NPC234337 |
0.7712 | Intermediate Similarity | NPC66208 |
0.771 | Intermediate Similarity | NPC78307 |
0.7699 | Intermediate Similarity | NPC244427 |
0.7699 | Intermediate Similarity | NPC222390 |
0.7685 | Intermediate Similarity | NPC125226 |
0.7685 | Intermediate Similarity | NPC141607 |
0.7685 | Intermediate Similarity | NPC187725 |
0.7674 | Intermediate Similarity | NPC25736 |
0.7672 | Intermediate Similarity | NPC472701 |
0.7672 | Intermediate Similarity | NPC21929 |
0.7672 | Intermediate Similarity | NPC472683 |
0.7672 | Intermediate Similarity | NPC472696 |
0.7672 | Intermediate Similarity | NPC472695 |
0.7667 | Intermediate Similarity | NPC217111 |
0.7667 | Intermediate Similarity | NPC93181 |
0.7667 | Intermediate Similarity | NPC186933 |
0.7667 | Intermediate Similarity | NPC474095 |
0.7667 | Intermediate Similarity | NPC221275 |
0.7667 | Intermediate Similarity | NPC476357 |
0.7656 | Intermediate Similarity | NPC84672 |
0.7656 | Intermediate Similarity | NPC176130 |
0.7656 | Intermediate Similarity | NPC78364 |
0.7656 | Intermediate Similarity | NPC69424 |
0.7652 | Intermediate Similarity | NPC202225 |
0.7652 | Intermediate Similarity | NPC23894 |
0.7642 | Intermediate Similarity | NPC204784 |
0.7634 | Intermediate Similarity | NPC144257 |
0.7632 | Intermediate Similarity | NPC19856 |
0.7627 | Intermediate Similarity | NPC137315 |
0.7623 | Intermediate Similarity | NPC45794 |
0.7615 | Intermediate Similarity | NPC188844 |
0.7615 | Intermediate Similarity | NPC1682 |
0.7611 | Intermediate Similarity | NPC472879 |
0.7607 | Intermediate Similarity | NPC475006 |
0.76 | Intermediate Similarity | NPC293831 |
0.76 | Intermediate Similarity | NPC369 |
0.7593 | Intermediate Similarity | NPC173413 |
0.7593 | Intermediate Similarity | NPC19256 |
0.7593 | Intermediate Similarity | NPC277277 |
0.7589 | Intermediate Similarity | NPC329387 |
0.7589 | Intermediate Similarity | NPC317280 |
0.7586 | Intermediate Similarity | NPC25385 |
0.7586 | Intermediate Similarity | NPC193640 |
0.7586 | Intermediate Similarity | NPC475905 |
0.7581 | Intermediate Similarity | NPC133302 |
0.7578 | Intermediate Similarity | NPC71610 |
0.7576 | Intermediate Similarity | NPC115458 |
0.757 | Intermediate Similarity | NPC267262 |
0.7559 | Intermediate Similarity | NPC295664 |
0.7547 | Intermediate Similarity | NPC307 |
0.7547 | Intermediate Similarity | NPC160339 |
0.754 | Intermediate Similarity | NPC65627 |
0.7538 | Intermediate Similarity | NPC262819 |
0.7538 | Intermediate Similarity | NPC276238 |
0.7537 | Intermediate Similarity | NPC472308 |
0.7523 | Intermediate Similarity | NPC284475 |
0.7521 | Intermediate Similarity | NPC211439 |
0.7521 | Intermediate Similarity | NPC274839 |
0.7521 | Intermediate Similarity | NPC203732 |
0.7521 | Intermediate Similarity | NPC228936 |
0.7521 | Intermediate Similarity | NPC470007 |
0.752 | Intermediate Similarity | NPC144547 |
0.7519 | Intermediate Similarity | NPC72667 |
0.75 | Intermediate Similarity | NPC470765 |
0.75 | Intermediate Similarity | NPC478107 |
0.75 | Intermediate Similarity | NPC275576 |
0.75 | Intermediate Similarity | NPC477476 |
0.75 | Intermediate Similarity | NPC470649 |
0.75 | Intermediate Similarity | NPC477475 |
0.7481 | Intermediate Similarity | NPC31799 |
0.7481 | Intermediate Similarity | NPC199253 |
0.7481 | Intermediate Similarity | NPC108129 |
0.7481 | Intermediate Similarity | NPC136588 |
0.748 | Intermediate Similarity | NPC198014 |
0.7477 | Intermediate Similarity | NPC69057 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC215419 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.8571 | High Similarity | NPD4141 | Clinical (unspecified phase) |
0.8318 | Intermediate Similarity | NPD3495 | Discontinued |
0.812 | Intermediate Similarity | NPD5951 | Approved |
0.8067 | Intermediate Similarity | NPD7610 | Discontinued |
0.7946 | Intermediate Similarity | NPD1930 | Approved |
0.7946 | Intermediate Similarity | NPD1931 | Clinical (unspecified phase) |
0.7946 | Intermediate Similarity | NPD1929 | Approved |
0.7851 | Intermediate Similarity | NPD7009 | Phase 2 |
0.7838 | Intermediate Similarity | NPD2066 | Phase 3 |
0.7724 | Intermediate Similarity | NPD3412 | Clinical (unspecified phase) |
0.7724 | Intermediate Similarity | NPD7163 | Clinical (unspecified phase) |
0.7699 | Intermediate Similarity | NPD1932 | Approved |
0.7615 | Intermediate Similarity | NPD7631 | Approved |
0.7607 | Intermediate Similarity | NPD2329 | Discontinued |
0.7538 | Intermediate Similarity | NPD7008 | Discontinued |
0.7538 | Intermediate Similarity | NPD5952 | Clinical (unspecified phase) |
0.7523 | Intermediate Similarity | NPD7609 | Phase 3 |
0.752 | Intermediate Similarity | NPD7457 | Clinical (unspecified phase) |
0.75 | Intermediate Similarity | NPD6858 | Approved |
0.75 | Intermediate Similarity | NPD7094 | Approved |
0.7459 | Intermediate Similarity | NPD3317 | Approved |
0.7424 | Intermediate Similarity | NPD7961 | Discontinued |
0.7387 | Intermediate Similarity | NPD5122 | Clinical (unspecified phase) |
0.7381 | Intermediate Similarity | NPD4879 | Approved |
0.7315 | Intermediate Similarity | NPD650 | Approved |
0.7311 | Intermediate Similarity | NPD6831 | Clinical (unspecified phase) |
0.7297 | Intermediate Similarity | NPD1088 | Approved |
0.7265 | Intermediate Similarity | NPD1237 | Approved |
0.7168 | Intermediate Similarity | NPD1693 | Approved |
0.7168 | Intermediate Similarity | NPD688 | Clinical (unspecified phase) |
0.7154 | Intermediate Similarity | NPD6010 | Discontinued |
0.7132 | Intermediate Similarity | NPD4878 | Approved |
0.7117 | Intermediate Similarity | NPD1089 | Approved |
0.7117 | Intermediate Similarity | NPD1090 | Approved |
0.7117 | Intermediate Similarity | NPD1086 | Approved |
0.7107 | Intermediate Similarity | NPD1317 | Discontinued |
0.7054 | Intermediate Similarity | NPD1201 | Approved |
0.7031 | Intermediate Similarity | NPD3019 | Approved |
0.7027 | Intermediate Similarity | NPD800 | Approved |
0.6991 | Remote Similarity | NPD1508 | Approved |
0.697 | Remote Similarity | NPD1470 | Approved |
0.696 | Remote Similarity | NPD2629 | Approved |
0.6957 | Remote Similarity | NPD1989 | Approved |
0.6923 | Remote Similarity | NPD7236 | Approved |
0.6916 | Remote Similarity | NPD942 | Approved |
0.6903 | Remote Similarity | NPD1239 | Approved |
0.6901 | Remote Similarity | NPD7003 | Approved |
0.6899 | Remote Similarity | NPD2932 | Approved |
0.6899 | Remote Similarity | NPD2345 | Approved |
0.6899 | Remote Similarity | NPD4199 | Phase 3 |
0.6897 | Remote Similarity | NPD1564 | Approved |
0.6897 | Remote Similarity | NPD1566 | Phase 3 |
0.6897 | Remote Similarity | NPD1565 | Approved |
0.6891 | Remote Similarity | NPD6647 | Phase 2 |
0.6891 | Remote Similarity | NPD5700 | Clinical (unspecified phase) |
0.687 | Remote Similarity | NPD6048 | Clinical (unspecified phase) |
0.687 | Remote Similarity | NPD6049 | Phase 2 |
0.6855 | Remote Similarity | NPD1609 | Clinical (unspecified phase) |
0.6847 | Remote Similarity | NPD1087 | Approved |
0.6833 | Remote Similarity | NPD5909 | Discontinued |
0.6822 | Remote Similarity | NPD4196 | Clinical (unspecified phase) |
0.681 | Remote Similarity | NPD1843 | Approved |
0.6803 | Remote Similarity | NPD7239 | Suspended |
0.6786 | Remote Similarity | NPD1509 | Clinical (unspecified phase) |
0.6777 | Remote Similarity | NPD5048 | Discontinued |
0.6774 | Remote Similarity | NPD2181 | Clinical (unspecified phase) |
0.6759 | Remote Similarity | NPD8165 | Discontinued |
0.6742 | Remote Similarity | NPD3972 | Approved |
0.6741 | Remote Similarity | NPD7084 | Phase 3 |
0.6738 | Remote Similarity | NPD5405 | Approved |
0.6738 | Remote Similarity | NPD5406 | Approved |
0.6738 | Remote Similarity | NPD5408 | Approved |
0.6738 | Remote Similarity | NPD5404 | Approved |
0.6726 | Remote Similarity | NPD5347 | Phase 2 |
0.6726 | Remote Similarity | NPD5346 | Phase 2 |
0.6718 | Remote Similarity | NPD3026 | Approved |
0.6718 | Remote Similarity | NPD3023 | Approved |
0.6692 | Remote Similarity | NPD5157 | Phase 1 |
0.6692 | Remote Similarity | NPD5159 | Phase 2 |
0.6692 | Remote Similarity | NPD3024 | Approved |
0.6692 | Remote Similarity | NPD5158 | Clinical (unspecified phase) |
0.6692 | Remote Similarity | NPD3025 | Approved |
0.669 | Remote Similarity | NPD2346 | Discontinued |
0.6667 | Remote Similarity | NPD6273 | Approved |
0.6667 | Remote Similarity | NPD6287 | Discontinued |
0.6667 | Remote Similarity | NPD6007 | Clinical (unspecified phase) |
0.6667 | Remote Similarity | NPD3673 | Approved |
0.6667 | Remote Similarity | NPD2798 | Approved |
0.6667 | Remote Similarity | NPD3672 | Approved |
0.6644 | Remote Similarity | NPD3226 | Approved |
0.6644 | Remote Similarity | NPD7458 | Discontinued |
0.6642 | Remote Similarity | NPD6330 | Clinical (unspecified phase) |
0.6641 | Remote Similarity | NPD5836 | Discontinued |
0.6638 | Remote Similarity | NPD1563 | Approved |
0.6613 | Remote Similarity | NPD2182 | Approved |
0.6606 | Remote Similarity | NPD226 | Approved |
0.6599 | Remote Similarity | NPD7422 | Clinical (unspecified phase) |
0.6594 | Remote Similarity | NPD5422 | Clinical (unspecified phase) |
0.6589 | Remote Similarity | NPD405 | Clinical (unspecified phase) |
0.6573 | Remote Similarity | NPD7702 | Clinical (unspecified phase) |
0.6549 | Remote Similarity | NPD4793 | Discontinued |
0.6547 | Remote Similarity | NPD7714 | Approved |
0.6547 | Remote Similarity | NPD6663 | Approved |
0.6547 | Remote Similarity | NPD7713 | Phase 3 |
0.6547 | Remote Similarity | NPD7715 | Approved |
0.6531 | Remote Similarity | NPD7390 | Discontinued |
0.6529 | Remote Similarity | NPD2193 | Phase 2 |
0.6529 | Remote Similarity | NPD2648 | Phase 3 |
0.6522 | Remote Similarity | NPD6966 | Discovery |
0.6514 | Remote Similarity | NPD1507 | Clinical (unspecified phase) |
0.6512 | Remote Similarity | NPD4198 | Discontinued |
0.6504 | Remote Similarity | NPD1018 | Approved |
0.65 | Remote Similarity | NPD7798 | Approved |
0.6496 | Remote Similarity | NPD5736 | Approved |
0.6489 | Remote Similarity | NPD3091 | Approved |
0.6486 | Remote Similarity | NPD9491 | Approved |
0.6484 | Remote Similarity | NPD2652 | Approved |
0.6484 | Remote Similarity | NPD4869 | Clinical (unspecified phase) |
0.6484 | Remote Similarity | NPD2650 | Approved |
0.6483 | Remote Similarity | NPD7421 | Clinical (unspecified phase) |
0.6475 | Remote Similarity | NPD6766 | Clinical (unspecified phase) |
0.6475 | Remote Similarity | NPD5765 | Approved |
0.6452 | Remote Similarity | NPD6685 | Approved |
0.6449 | Remote Similarity | NPD7055 | Discontinued |
0.6446 | Remote Similarity | NPD3135 | Clinical (unspecified phase) |
0.6444 | Remote Similarity | NPD182 | Clinical (unspecified phase) |
0.6439 | Remote Similarity | NPD1245 | Approved |
0.6438 | Remote Similarity | NPD4628 | Phase 3 |
0.6438 | Remote Similarity | NPD8166 | Discontinued |
0.6434 | Remote Similarity | NPD2799 | Discontinued |
0.6424 | Remote Similarity | NPD5808 | Clinical (unspecified phase) |
0.6423 | Remote Similarity | NPD4980 | Approved |
0.6423 | Remote Similarity | NPD164 | Approved |
0.6418 | Remote Similarity | NPD5618 | Discontinued |
0.6412 | Remote Similarity | NPD6065 | Approved |
0.6408 | Remote Similarity | NPD6817 | Clinical (unspecified phase) |
0.6397 | Remote Similarity | NPD1283 | Approved |
0.6397 | Remote Similarity | NPD1876 | Approved |
0.6393 | Remote Similarity | NPD2196 | Discontinued |
0.6391 | Remote Similarity | NPD3095 | Discontinued |
0.6387 | Remote Similarity | NPD7057 | Phase 3 |
0.6387 | Remote Similarity | NPD7058 | Phase 2 |
0.6383 | Remote Similarity | NPD7966 | Clinical (unspecified phase) |
0.6379 | Remote Similarity | NPD9258 | Approved |
0.6379 | Remote Similarity | NPD9256 | Approved |
0.6378 | Remote Similarity | NPD3643 | Approved |
0.6378 | Remote Similarity | NPD3644 | Approved |
0.6378 | Remote Similarity | NPD3642 | Approved |
0.6372 | Remote Similarity | NPD5734 | Clinical (unspecified phase) |
0.637 | Remote Similarity | NPD6637 | Approved |
0.6364 | Remote Similarity | NPD1238 | Approved |
0.6364 | Remote Similarity | NPD7741 | Discontinued |
0.6357 | Remote Similarity | NPD2313 | Discontinued |
0.6356 | Remote Similarity | NPD1202 | Approved |
0.6351 | Remote Similarity | NPD3300 | Phase 2 |
0.635 | Remote Similarity | NPD1164 | Approved |
0.6339 | Remote Similarity | NPD3971 | Phase 1 |
0.6335 | Remote Similarity | NPD7799 | Discontinued |
0.633 | Remote Similarity | NPD225 | Approved |
0.633 | Remote Similarity | NPD227 | Approved |
0.6325 | Remote Similarity | NPD6079 | Approved |
0.6323 | Remote Similarity | NPD8443 | Clinical (unspecified phase) |
0.6319 | Remote Similarity | NPD3299 | Clinical (unspecified phase) |
0.6319 | Remote Similarity | NPD7305 | Phase 1 |
0.6316 | Remote Similarity | NPD6591 | Clinical (unspecified phase) |
0.6316 | Remote Similarity | NPD1651 | Approved |
0.6308 | Remote Similarity | NPD1711 | Phase 2 |
0.6308 | Remote Similarity | NPD4766 | Approved |
0.6308 | Remote Similarity | NPD1246 | Approved |
0.6304 | Remote Similarity | NPD6085 | Phase 2 |
0.6304 | Remote Similarity | NPD5740 | Clinical (unspecified phase) |
0.6303 | Remote Similarity | NPD4629 | Approved |
0.6303 | Remote Similarity | NPD4814 | Discontinued |
0.6303 | Remote Similarity | NPD4094 | Approved |
0.6303 | Remote Similarity | NPD5210 | Approved |
0.6299 | Remote Similarity | NPD3646 | Clinical (unspecified phase) |
0.6296 | Remote Similarity | NPD3092 | Approved |
0.6296 | Remote Similarity | NPD4216 | Approved |
0.6296 | Remote Similarity | NPD4215 | Approved |
0.6296 | Remote Similarity | NPD3132 | Approved |
0.6296 | Remote Similarity | NPD2611 | Approved |
0.6296 | Remote Similarity | NPD3131 | Approved |
0.6296 | Remote Similarity | NPD2610 | Approved |
0.6296 | Remote Similarity | NPD2608 | Approved |
0.6296 | Remote Similarity | NPD4218 | Approved |
0.6296 | Remote Similarity | NPD2612 | Approved |
0.6296 | Remote Similarity | NPD2609 | Approved |
0.6296 | Remote Similarity | NPD4217 | Approved |
0.6294 | Remote Similarity | NPD3528 | Clinical (unspecified phase) |
0.6284 | Remote Similarity | NPD7295 | Approved |
0.6283 | Remote Similarity | NPD3665 | Phase 1 |
0.6283 | Remote Similarity | NPD3666 | Approved |
0.6283 | Remote Similarity | NPD3133 | Approved |
0.6281 | Remote Similarity | NPD9495 | Approved |
0.6261 | Remote Similarity | NPD506 | Clinical (unspecified phase) |
0.6258 | Remote Similarity | NPD7819 | Suspended |
0.625 | Remote Similarity | NPD3880 | Clinical (unspecified phase) |
0.625 | Remote Similarity | NPD5206 | Clinical (unspecified phase) |
0.6241 | Remote Similarity | NPD2846 | Clinical (unspecified phase) |
0.6241 | Remote Similarity | NPD3764 | Approved |
PubChem CID   | 21672229 |
ChEMBL   | CHEMBL444235 |
ZINC   |
Molecular Weight:   | 314.19 |
ALogP:   | 0.1421 |
MLogP:   | 3.33 |
XLogP:   | 4.495 |
# Rotatable Bonds:   | 7 |
Polar Surface Area:   | 54.37 |
# H-Bond Aceptor:   | 3 |
# H-Bond Donor:   | 1 |
# Rings:   | 3 |
# Heavy Atoms:   | 23 |