Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT2 | Others | Unspecified | Inhibition | = | 97.3 | % | 18942825 | |
NPT2 | Others | Unspecified | Inhibition | = | 98.4 | % | 10924177 | |
NPT2 | Others | Unspecified | IC50 | = | 1330 | nM | 24224843 | |
NPT2 | Others | Unspecified | IC50 | = | 900 | nM | 15969497 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC196243 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.9745 | High Similarity | NPC276506 |
0.9745 | High Similarity | NPC198254 |
0.9745 | High Similarity | NPC274198 |
0.9554 | High Similarity | NPC304074 |
0.9554 | High Similarity | NPC290755 |
0.9554 | High Similarity | NPC471771 |
0.949 | High Similarity | NPC223207 |
0.9299 | High Similarity | NPC475544 |
0.9299 | High Similarity | NPC469243 |
0.9212 | High Similarity | NPC153554 |
0.9045 | High Similarity | NPC473580 |
0.8909 | High Similarity | NPC475532 |
0.8855 | High Similarity | NPC165285 |
0.8786 | High Similarity | NPC240130 |
0.8786 | High Similarity | NPC61332 |
0.8727 | High Similarity | NPC129486 |
0.8636 | High Similarity | NPC302715 |
0.8631 | High Similarity | NPC17698 |
0.8596 | High Similarity | NPC473404 |
0.8563 | High Similarity | NPC94862 |
0.8503 | High Similarity | NPC280022 |
0.85 | High Similarity | NPC233702 |
0.848 | Intermediate Similarity | NPC119652 |
0.848 | Intermediate Similarity | NPC97526 |
0.8443 | Intermediate Similarity | NPC328649 |
0.8353 | Intermediate Similarity | NPC306804 |
0.8323 | Intermediate Similarity | NPC63931 |
0.8305 | Intermediate Similarity | NPC102959 |
0.8258 | Intermediate Similarity | NPC60516 |
0.825 | Intermediate Similarity | NPC16188 |
0.8225 | Intermediate Similarity | NPC141957 |
0.8221 | Intermediate Similarity | NPC202198 |
0.8217 | Intermediate Similarity | NPC48202 |
0.8198 | Intermediate Similarity | NPC155506 |
0.8198 | Intermediate Similarity | NPC159767 |
0.8187 | Intermediate Similarity | NPC230611 |
0.8166 | Intermediate Similarity | NPC61004 |
0.8161 | Intermediate Similarity | NPC45037 |
0.8161 | Intermediate Similarity | NPC269750 |
0.8161 | Intermediate Similarity | NPC194671 |
0.8153 | Intermediate Similarity | NPC132636 |
0.814 | Intermediate Similarity | NPC137627 |
0.8129 | Intermediate Similarity | NPC46009 |
0.8095 | Intermediate Similarity | NPC241794 |
0.8092 | Intermediate Similarity | NPC473402 |
0.8092 | Intermediate Similarity | NPC279871 |
0.8079 | Intermediate Similarity | NPC294951 |
0.8077 | Intermediate Similarity | NPC477632 |
0.8077 | Intermediate Similarity | NPC477638 |
0.8046 | Intermediate Similarity | NPC50016 |
0.8043 | Intermediate Similarity | NPC477552 |
0.8043 | Intermediate Similarity | NPC477550 |
0.8035 | Intermediate Similarity | NPC273755 |
0.8012 | Intermediate Similarity | NPC294516 |
0.8012 | Intermediate Similarity | NPC107938 |
0.7989 | Intermediate Similarity | NPC26108 |
0.7989 | Intermediate Similarity | NPC476227 |
0.7977 | Intermediate Similarity | NPC89831 |
0.7962 | Intermediate Similarity | NPC267237 |
0.7957 | Intermediate Similarity | NPC477551 |
0.7947 | Intermediate Similarity | NPC478005 |
0.7937 | Intermediate Similarity | NPC476989 |
0.7935 | Intermediate Similarity | NPC477639 |
0.7919 | Intermediate Similarity | NPC475123 |
0.7919 | Intermediate Similarity | NPC475204 |
0.7919 | Intermediate Similarity | NPC40234 |
0.7914 | Intermediate Similarity | NPC311658 |
0.791 | Intermediate Similarity | NPC475409 |
0.791 | Intermediate Similarity | NPC475564 |
0.791 | Intermediate Similarity | NPC170302 |
0.7898 | Intermediate Similarity | NPC244866 |
0.7892 | Intermediate Similarity | NPC261934 |
0.7892 | Intermediate Similarity | NPC56685 |
0.7892 | Intermediate Similarity | NPC5194 |
0.7886 | Intermediate Similarity | NPC473354 |
0.7861 | Intermediate Similarity | NPC66490 |
0.7861 | Intermediate Similarity | NPC469443 |
0.7857 | Intermediate Similarity | NPC473305 |
0.7857 | Intermediate Similarity | NPC163961 |
0.7857 | Intermediate Similarity | NPC477636 |
0.7838 | Intermediate Similarity | NPC329295 |
0.7834 | Intermediate Similarity | NPC326966 |
0.7829 | Intermediate Similarity | NPC248670 |
0.7821 | Intermediate Similarity | NPC471526 |
0.7797 | Intermediate Similarity | NPC473546 |
0.7784 | Intermediate Similarity | NPC136797 |
0.7784 | Intermediate Similarity | NPC262166 |
0.7784 | Intermediate Similarity | NPC471165 |
0.7784 | Intermediate Similarity | NPC158277 |
0.7772 | Intermediate Similarity | NPC477631 |
0.7771 | Intermediate Similarity | NPC473491 |
0.7765 | Intermediate Similarity | NPC244336 |
0.7764 | Intermediate Similarity | NPC214988 |
0.7707 | Intermediate Similarity | NPC325651 |
0.7706 | Intermediate Similarity | NPC326349 |
0.7706 | Intermediate Similarity | NPC323336 |
0.7705 | Intermediate Similarity | NPC234069 |
0.7701 | Intermediate Similarity | NPC209463 |
0.7701 | Intermediate Similarity | NPC302597 |
0.7667 | Intermediate Similarity | NPC476321 |
0.7663 | Intermediate Similarity | NPC174122 |
0.7663 | Intermediate Similarity | NPC64140 |
0.7661 | Intermediate Similarity | NPC287757 |
0.7661 | Intermediate Similarity | NPC319320 |
0.7637 | Intermediate Similarity | NPC138083 |
0.7617 | Intermediate Similarity | NPC220060 |
0.7611 | Intermediate Similarity | NPC32064 |
0.761 | Intermediate Similarity | NPC257390 |
0.76 | Intermediate Similarity | NPC478007 |
0.7593 | Intermediate Similarity | NPC242159 |
0.7593 | Intermediate Similarity | NPC313694 |
0.7588 | Intermediate Similarity | NPC244509 |
0.7584 | Intermediate Similarity | NPC164608 |
0.7582 | Intermediate Similarity | NPC471048 |
0.7582 | Intermediate Similarity | NPC471049 |
0.7582 | Intermediate Similarity | NPC471050 |
0.7579 | Intermediate Similarity | NPC473450 |
0.7578 | Intermediate Similarity | NPC314835 |
0.7577 | Intermediate Similarity | NPC469444 |
0.7561 | Intermediate Similarity | NPC168861 |
0.7558 | Intermediate Similarity | NPC1390 |
0.7558 | Intermediate Similarity | NPC62104 |
0.7554 | Intermediate Similarity | NPC96275 |
0.753 | Intermediate Similarity | NPC81026 |
0.753 | Intermediate Similarity | NPC314114 |
0.7529 | Intermediate Similarity | NPC289776 |
0.7529 | Intermediate Similarity | NPC191863 |
0.7529 | Intermediate Similarity | NPC133470 |
0.7527 | Intermediate Similarity | NPC473407 |
0.7527 | Intermediate Similarity | NPC473378 |
0.7525 | Intermediate Similarity | NPC478008 |
0.7516 | Intermediate Similarity | NPC477937 |
0.7514 | Intermediate Similarity | NPC114806 |
0.75 | Intermediate Similarity | NPC324850 |
0.7485 | Intermediate Similarity | NPC476268 |
0.7473 | Intermediate Similarity | NPC51047 |
0.7473 | Intermediate Similarity | NPC477637 |
0.747 | Intermediate Similarity | NPC266741 |
0.7462 | Intermediate Similarity | NPC469445 |
0.7457 | Intermediate Similarity | NPC24617 |
0.7446 | Intermediate Similarity | NPC235194 |
0.7446 | Intermediate Similarity | NPC299806 |
0.7438 | Intermediate Similarity | NPC255447 |
0.7436 | Intermediate Similarity | NPC219350 |
0.7436 | Intermediate Similarity | NPC194699 |
0.7421 | Intermediate Similarity | NPC111428 |
0.7412 | Intermediate Similarity | NPC300443 |
0.7405 | Intermediate Similarity | NPC276120 |
0.7386 | Intermediate Similarity | NPC210377 |
0.7386 | Intermediate Similarity | NPC217804 |
0.7386 | Intermediate Similarity | NPC22883 |
0.7386 | Intermediate Similarity | NPC5719 |
0.7379 | Intermediate Similarity | NPC323244 |
0.7353 | Intermediate Similarity | NPC324081 |
0.7345 | Intermediate Similarity | NPC15068 |
0.733 | Intermediate Similarity | NPC471592 |
0.7326 | Intermediate Similarity | NPC246591 |
0.7326 | Intermediate Similarity | NPC39431 |
0.7312 | Intermediate Similarity | NPC473322 |
0.7303 | Intermediate Similarity | NPC63040 |
0.7288 | Intermediate Similarity | NPC472923 |
0.7287 | Intermediate Similarity | NPC29531 |
0.7286 | Intermediate Similarity | NPC277306 |
0.7286 | Intermediate Similarity | NPC469442 |
0.7278 | Intermediate Similarity | NPC328494 |
0.7267 | Intermediate Similarity | NPC473341 |
0.7263 | Intermediate Similarity | NPC65714 |
0.7263 | Intermediate Similarity | NPC328763 |
0.7261 | Intermediate Similarity | NPC27581 |
0.7249 | Intermediate Similarity | NPC470728 |
0.7249 | Intermediate Similarity | NPC248822 |
0.7238 | Intermediate Similarity | NPC328924 |
0.7225 | Intermediate Similarity | NPC80514 |
0.7214 | Intermediate Similarity | NPC25539 |
0.7202 | Intermediate Similarity | NPC326241 |
0.7197 | Intermediate Similarity | NPC71684 |
0.7188 | Intermediate Similarity | NPC473371 |
0.7184 | Intermediate Similarity | NPC469903 |
0.7174 | Intermediate Similarity | NPC475421 |
0.7173 | Intermediate Similarity | NPC314083 |
0.7168 | Intermediate Similarity | NPC122590 |
0.7167 | Intermediate Similarity | NPC469904 |
0.7167 | Intermediate Similarity | NPC186617 |
0.7166 | Intermediate Similarity | NPC315542 |
0.7143 | Intermediate Similarity | NPC91953 |
0.7135 | Intermediate Similarity | NPC471563 |
0.7127 | Intermediate Similarity | NPC471568 |
0.7127 | Intermediate Similarity | NPC473693 |
0.7127 | Intermediate Similarity | NPC196091 |
0.7119 | Intermediate Similarity | NPC473003 |
0.7119 | Intermediate Similarity | NPC469902 |
0.7119 | Intermediate Similarity | NPC471527 |
0.7113 | Intermediate Similarity | NPC50548 |
0.7113 | Intermediate Similarity | NPC323662 |
0.7111 | Intermediate Similarity | NPC473502 |
0.7102 | Intermediate Similarity | NPC56635 |
0.7099 | Intermediate Similarity | NPC296712 |
0.7083 | Intermediate Similarity | NPC197921 |
0.7072 | Intermediate Similarity | NPC315388 |
0.707 | Intermediate Similarity | NPC283760 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC196243 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.8951 | High Similarity | NPD8303 | Discontinued |
0.8875 | High Similarity | NPD8019 | Approved |
0.8758 | High Similarity | NPD7495 | Discontinued |
0.8447 | Intermediate Similarity | NPD7523 | Phase 3 |
0.7937 | Intermediate Similarity | NPD7450 | Phase 2 |
0.7888 | Intermediate Similarity | NPD8076 | Discontinued |
0.7857 | Intermediate Similarity | NPD7617 | Discontinued |
0.7853 | Intermediate Similarity | NPD7066 | Clinical (unspecified phase) |
0.7811 | Intermediate Similarity | NPD7118 | Clinical (unspecified phase) |
0.7778 | Intermediate Similarity | NPD6809 | Clinical (unspecified phase) |
0.7702 | Intermediate Similarity | NPD6901 | Phase 3 |
0.7684 | Intermediate Similarity | NPD5200 | Clinical (unspecified phase) |
0.7633 | Intermediate Similarity | NPD6670 | Clinical (unspecified phase) |
0.7619 | Intermediate Similarity | NPD6078 | Clinical (unspecified phase) |
0.7515 | Intermediate Similarity | NPD7303 | Discontinued |
0.744 | Intermediate Similarity | NPD8290 | Clinical (unspecified phase) |
0.7353 | Intermediate Similarity | NPD5348 | Clinical (unspecified phase) |
0.7333 | Intermediate Similarity | NPD6866 | Clinical (unspecified phase) |
0.7333 | Intermediate Similarity | NPD6867 | Clinical (unspecified phase) |
0.7329 | Intermediate Similarity | NPD3136 | Phase 2 |
0.7317 | Intermediate Similarity | NPD4782 | Clinical (unspecified phase) |
0.7301 | Intermediate Similarity | NPD4791 | Clinical (unspecified phase) |
0.7263 | Intermediate Similarity | NPD7484 | Phase 3 |
0.7263 | Intermediate Similarity | NPD7485 | Phase 3 |
0.7258 | Intermediate Similarity | NPD5946 | Clinical (unspecified phase) |
0.725 | Intermediate Similarity | NPD7451 | Discontinued |
0.7246 | Intermediate Similarity | NPD7978 | Discontinued |
0.7222 | Intermediate Similarity | NPD7608 | Discontinued |
0.7222 | Intermediate Similarity | NPD4652 | Approved |
0.7193 | Intermediate Similarity | NPD6682 | Clinical (unspecified phase) |
0.7191 | Intermediate Similarity | NPD2098 | Approved |
0.7168 | Intermediate Similarity | NPD7131 | Phase 3 |
0.7143 | Intermediate Similarity | NPD5339 | Clinical (unspecified phase) |
0.7135 | Intermediate Similarity | NPD6297 | Approved |
0.7135 | Intermediate Similarity | NPD5445 | Approved |
0.7101 | Intermediate Similarity | NPD5341 | Clinical (unspecified phase) |
0.7088 | Intermediate Similarity | NPD5137 | Approved |
0.7079 | Intermediate Similarity | NPD2097 | Approved |
0.7074 | Intermediate Similarity | NPD6851 | Approved |
0.7074 | Intermediate Similarity | NPD6853 | Approved |
0.7072 | Intermediate Similarity | NPD2888 | Approved |
0.7072 | Intermediate Similarity | NPD2890 | Approved |
0.7072 | Intermediate Similarity | NPD2017 | Approved |
0.7072 | Intermediate Similarity | NPD2889 | Approved |
0.7065 | Intermediate Similarity | NPD8022 | Clinical (unspecified phase) |
0.7063 | Intermediate Similarity | NPD4677 | Discontinued |
0.7055 | Intermediate Similarity | NPD5263 | Approved |
0.7048 | Intermediate Similarity | NPD8292 | Phase 2 |
0.703 | Intermediate Similarity | NPD5729 | Clinical (unspecified phase) |
0.7 | Intermediate Similarity | NPD3071 | Approved |
0.7 | Intermediate Similarity | NPD3073 | Approved |
0.7 | Intermediate Similarity | NPD3072 | Approved |
0.6988 | Remote Similarity | NPD6346 | Approved |
0.6983 | Remote Similarity | NPD5967 | Approved |
0.697 | Remote Similarity | NPD1329 | Clinical (unspecified phase) |
0.697 | Remote Similarity | NPD1330 | Phase 2 |
0.697 | Remote Similarity | NPD3632 | Clinical (unspecified phase) |
0.6946 | Remote Similarity | NPD3908 | Approved |
0.6937 | Remote Similarity | NPD4761 | Approved |
0.6937 | Remote Similarity | NPD4762 | Approved |
0.6923 | Remote Similarity | NPD5301 | Clinical (unspecified phase) |
0.6909 | Remote Similarity | NPD6919 | Clinical (unspecified phase) |
0.6905 | Remote Similarity | NPD6073 | Approved |
0.6882 | Remote Similarity | NPD6897 | Clinical (unspecified phase) |
0.6879 | Remote Similarity | NPD9568 | Approved |
0.6879 | Remote Similarity | NPD8323 | Discontinued |
0.6867 | Remote Similarity | NPD5581 | Approved |
0.686 | Remote Similarity | NPD6860 | Clinical (unspecified phase) |
0.6859 | Remote Similarity | NPD6967 | Phase 2 |
0.6855 | Remote Similarity | NPD4504 | Clinical (unspecified phase) |
0.6848 | Remote Similarity | NPD4676 | Approved |
0.6842 | Remote Similarity | NPD7720 | Phase 2 |
0.6839 | Remote Similarity | NPD7554 | Discontinued |
0.6834 | Remote Similarity | NPD6255 | Approved |
0.6834 | Remote Similarity | NPD6254 | Approved |
0.6834 | Remote Similarity | NPD6256 | Approved |
0.6827 | Remote Similarity | NPD8405 | Clinical (unspecified phase) |
0.6824 | Remote Similarity | NPD7728 | Clinical (unspecified phase) |
0.6813 | Remote Similarity | NPD8031 | Discontinued |
0.681 | Remote Similarity | NPD3125 | Approved |
0.6804 | Remote Similarity | NPD7283 | Approved |
0.6802 | Remote Similarity | NPD6681 | Discovery |
0.68 | Remote Similarity | NPD8163 | Clinical (unspecified phase) |
0.68 | Remote Similarity | NPD8162 | Phase 2 |
0.6788 | Remote Similarity | NPD4177 | Approved |
0.6788 | Remote Similarity | NPD4175 | Approved |
0.6788 | Remote Similarity | NPD3040 | Approved |
0.6784 | Remote Similarity | NPD6253 | Approved |
0.6782 | Remote Similarity | NPD7602 | Clinical (unspecified phase) |
0.6766 | Remote Similarity | NPD5152 | Clinical (unspecified phase) |
0.6758 | Remote Similarity | NPD4565 | Clinical (unspecified phase) |
0.6758 | Remote Similarity | NPD4564 | Clinical (unspecified phase) |
0.6746 | Remote Similarity | NPD4757 | Clinical (unspecified phase) |
0.6743 | Remote Similarity | NPD6884 | Clinical (unspecified phase) |
0.6734 | Remote Similarity | NPD7811 | Phase 3 |
0.6734 | Remote Similarity | NPD7810 | Phase 3 |
0.6728 | Remote Similarity | NPD4706 | Clinical (unspecified phase) |
0.6727 | Remote Similarity | NPD4151 | Approved |
0.6723 | Remote Similarity | NPD7613 | Discontinued |
0.672 | Remote Similarity | NPD7695 | Clinical (unspecified phase) |
0.6719 | Remote Similarity | NPD6556 | Clinical (unspecified phase) |
0.6717 | Remote Similarity | NPD7282 | Approved |
0.6715 | Remote Similarity | NPD6188 | Approved |
0.6715 | Remote Similarity | NPD6189 | Approved |
0.6706 | Remote Similarity | NPD5725 | Approved |
0.6705 | Remote Similarity | NPD6088 | Approved |
0.6705 | Remote Similarity | NPD7596 | Clinical (unspecified phase) |
0.6701 | Remote Similarity | NPD7669 | Phase 3 |
0.6687 | Remote Similarity | NPD2561 | Approved |
0.6687 | Remote Similarity | NPD2562 | Approved |
0.6687 | Remote Similarity | NPD9569 | Approved |
0.6686 | Remote Similarity | NPD6623 | Phase 3 |
0.6667 | Remote Similarity | NPD3055 | Approved |
0.6667 | Remote Similarity | NPD6747 | Phase 1 |
0.6667 | Remote Similarity | NPD3053 | Approved |
0.6667 | Remote Similarity | NPD2976 | Clinical (unspecified phase) |
0.6667 | Remote Similarity | NPD6187 | Approved |
0.6667 | Remote Similarity | NPD6294 | Approved |
0.6667 | Remote Similarity | NPD6295 | Approved |
0.6649 | Remote Similarity | NPD6089 | Clinical (unspecified phase) |
0.6649 | Remote Similarity | NPD8103 | Clinical (unspecified phase) |
0.663 | Remote Similarity | NPD2541 | Clinical (unspecified phase) |
0.6629 | Remote Similarity | NPD3400 | Discontinued |
0.6629 | Remote Similarity | NPD1967 | Approved |
0.6629 | Remote Similarity | NPD1968 | Approved |
0.6627 | Remote Similarity | NPD259 | Phase 1 |
0.6615 | Remote Similarity | NPD7132 | Clinical (unspecified phase) |
0.6615 | Remote Similarity | NPD8025 | Phase 2 |
0.661 | Remote Similarity | NPD6631 | Clinical (unspecified phase) |
0.6608 | Remote Similarity | NPD2568 | Approved |
0.6607 | Remote Similarity | NPD4497 | Clinical (unspecified phase) |
0.6606 | Remote Similarity | NPD5311 | Approved |
0.6606 | Remote Similarity | NPD5310 | Approved |
0.6604 | Remote Similarity | NPD256 | Approved |
0.6604 | Remote Similarity | NPD255 | Approved |
0.6601 | Remote Similarity | NPD6480 | Clinical (unspecified phase) |
0.6595 | Remote Similarity | NPD8245 | Clinical (unspecified phase) |
0.6593 | Remote Similarity | NPD5355 | Approved |
0.6593 | Remote Similarity | NPD5356 | Approved |
0.6591 | Remote Similarity | NPD7910 | Clinical (unspecified phase) |
0.6588 | Remote Similarity | NPD4153 | Approved |
0.6588 | Remote Similarity | NPD5296 | Approved |
0.6573 | Remote Similarity | NPD6796 | Discontinued |
0.6571 | Remote Similarity | NPD2211 | Approved |
0.6571 | Remote Similarity | NPD2209 | Approved |
0.657 | Remote Similarity | NPD3553 | Approved |
0.657 | Remote Similarity | NPD3552 | Approved |
0.657 | Remote Similarity | NPD3554 | Approved |
0.657 | Remote Similarity | NPD3555 | Approved |
0.6566 | Remote Similarity | NPD2585 | Clinical (unspecified phase) |
0.6562 | Remote Similarity | NPD5192 | Clinical (unspecified phase) |
0.655 | Remote Similarity | NPD555 | Phase 2 |
0.655 | Remote Similarity | NPD8643 | Discontinued |
0.6548 | Remote Similarity | NPD7979 | Clinical (unspecified phase) |
0.6548 | Remote Similarity | NPD7668 | Phase 2 |
0.6546 | Remote Similarity | NPD6557 | Phase 2 |
0.6531 | Remote Similarity | NPD7855 | Clinical (unspecified phase) |
0.6529 | Remote Similarity | NPD5745 | Approved |
0.6529 | Remote Similarity | NPD5747 | Discontinued |
0.6529 | Remote Similarity | NPD7634 | Clinical (unspecified phase) |
0.6517 | Remote Similarity | NPD5856 | Discontinued |
0.6512 | Remote Similarity | NPD8172 | Phase 2 |
0.6512 | Remote Similarity | NPD8173 | Phase 2 |
0.6512 | Remote Similarity | NPD5314 | Approved |
0.6509 | Remote Similarity | NPD9537 | Phase 1 |
0.6509 | Remote Similarity | NPD9536 | Phase 1 |
0.6495 | Remote Similarity | NPD7280 | Phase 3 |
0.6495 | Remote Similarity | NPD7281 | Phase 3 |
0.6491 | Remote Similarity | NPD5323 | Approved |
0.6474 | Remote Similarity | NPD4126 | Approved |
0.6474 | Remote Similarity | NPD8154 | Clinical (unspecified phase) |
0.6474 | Remote Similarity | NPD6852 | Discontinued |
0.6474 | Remote Similarity | NPD6720 | Clinical (unspecified phase) |
0.6458 | Remote Similarity | NPD5557 | Phase 1 |
0.6458 | Remote Similarity | NPD5484 | Approved |
0.6458 | Remote Similarity | NPD5485 | Approved |
0.6452 | Remote Similarity | NPD8070 | Approved |
0.645 | Remote Similarity | NPD6359 | Clinical (unspecified phase) |
0.645 | Remote Similarity | NPD4125 | Approved |
0.6448 | Remote Similarity | NPD6677 | Suspended |
0.6447 | Remote Similarity | NPD6835 | Approved |
0.6447 | Remote Similarity | NPD4157 | Discontinued |
0.6446 | Remote Similarity | NPD4659 | Approved |
0.6444 | Remote Similarity | NPD4186 | Clinical (unspecified phase) |
0.6432 | Remote Similarity | NPD7080 | Clinical (unspecified phase) |
0.6432 | Remote Similarity | NPD6646 | Discontinued |
0.6429 | Remote Similarity | NPD3455 | Phase 2 |
0.6429 | Remote Similarity | NPD258 | Approved |
0.6429 | Remote Similarity | NPD257 | Approved |
0.6429 | Remote Similarity | NPD3608 | Clinical (unspecified phase) |
0.6425 | Remote Similarity | NPD5614 | Approved |
0.6425 | Remote Similarity | NPD6973 | Clinical (unspecified phase) |
0.6425 | Remote Similarity | NPD5613 | Approved |
0.6421 | Remote Similarity | NPD3451 | Clinical (unspecified phase) |
0.642 | Remote Similarity | NPD4256 | Phase 2 |
0.642 | Remote Similarity | NPD4257 | Approved |
0.6416 | Remote Similarity | NPD6817 | Clinical (unspecified phase) |
0.6413 | Remote Similarity | NPD7011 | Discontinued |
0.6412 | Remote Similarity | NPD5746 | Approved |
0.6411 | Remote Similarity | NPD3803 | Clinical (unspecified phase) |
PubChem CID   | 11051314 |
ChEMBL   | CHEMBL453427 |
ZINC   |
Molecular Weight:   | 956.51 |
ALogP:   | -5.639 |
MLogP:   | 4.65 |
XLogP:   | 5.586 |
# Rotatable Bonds:   | 31 |
Polar Surface Area:   | 334.95 |
# H-Bond Aceptor:   | 18 |
# H-Bond Donor:   | 12 |
# Rings:   | 4 |
# Heavy Atoms:   | 69 |