Natural Product: NPC180504

Natural Product ID:  NPC180504
Common Name:   A-443654
IUPAC Name:   (2S)-1-(1H-indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan-2-amine
Synonyms:   A-443654; A-4436554
Molecular Formula:   C24H23N5O
Standard InCHIKey:  YWTBGJGMTBHQTM-IBGZPJMESA-N
Standard InCHI:  InChI=1S/C24H23N5O/c1-15-22-10-16(6-7-24(22)29-28-15)17-9-20(13-26-11-17)30-14-19(25)8-18-12-27-23-5-3-2-4-21(18)23/h2-7,9-13,19,27H,8,14,25H2,1H3,(H,28,29)/t19-/m0/s1
Canonical SMILES:  N[C@@H](Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)c(C)[nH]n2
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO14928 Huperzia serrata Species Lycopodiaceae Eukaryota HerDing*
NPO14928 Huperzia serrata Species Lycopodiaceae Eukaryota TCMID*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT783 Cell Line MIA PaCa-2 Homo sapiens EC50 = 100 nM 16678413
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens Ki = 0.16 nM 16678413
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens IC50 = 0.16 nM 17523610
NPT1016 Organism Canis familiaris Canis lupus familiaris Activity = 60 mmHg 17523610
NPT3106 Individual Protein Ribosomal protein S6 kinase alpha 1 Homo sapiens Activity = 78 % 17850214
NPT3106 Individual Protein Ribosomal protein S6 kinase alpha 1 Homo sapiens Activity = 32 % 17850214
NPT1614 Individual Protein MAP kinase p38 delta Homo sapiens Activity = 86 % 17850214
NPT1614 Individual Protein MAP kinase p38 delta Homo sapiens Activity = 68 % 17850214
NPT1615 Individual Protein MAP kinase p38 gamma Homo sapiens Activity = 87 % 17850214
NPT1615 Individual Protein MAP kinase p38 gamma Homo sapiens Activity = 83 % 17850214
NPT1695 Individual Protein Serine/threonine-protein kinase PAK 4 Homo sapiens Activity = 99 % 17850214
NPT1695 Individual Protein Serine/threonine-protein kinase PAK 4 Homo sapiens Activity = 90 % 17850214
NPT3107 Individual Protein Rho-associated protein kinase 2 Homo sapiens Activity = 8 % 17850214
NPT1696 Individual Protein Serine/threonine-protein kinase PAK7 Homo sapiens Activity = 104 % 17850214
NPT1696 Individual Protein Serine/threonine-protein kinase PAK7 Homo sapiens Activity = 96 % 17850214
NPT1697 Individual Protein Serine/threonine-protein kinase PAK6 Homo sapiens Activity = 87 % 17850214
NPT1699 Individual Protein 3-phosphoinositide dependent protein kinase-1 Homo sapiens Activity = 88 % 17850214
NPT1699 Individual Protein 3-phosphoinositide dependent protein kinase-1 Homo sapiens Activity = 79 % 17850214
NPT2 Others Unspecified Activity = 86 % 17850214
NPT2 Others Unspecified Activity = 54 % 17850214
NPT1265 Individual Protein Serine/threonine-protein kinase PIM1 Homo sapiens Activity = 57 % 17850214
NPT1265 Individual Protein Serine/threonine-protein kinase PIM1 Homo sapiens Activity = 15 % 17850214
NPT1700 Individual Protein Serine/threonine-protein kinase PIM2 Homo sapiens Activity = 59 % 17850214
NPT1700 Individual Protein Serine/threonine-protein kinase PIM2 Homo sapiens Activity = 15 % 17850214
NPT1701 Individual Protein Serine/threonine-protein kinase PIM3 Homo sapiens Activity = 54 % 17850214
NPT1701 Individual Protein Serine/threonine-protein kinase PIM3 Homo sapiens Activity = 13 % 17850214
NPT1703 Individual Protein cAMP-dependent protein kinase alpha-catalytic subunit Homo sapiens Activity = 26 % 17850214
NPT1703 Individual Protein cAMP-dependent protein kinase alpha-catalytic subunit Homo sapiens Activity = 3 % 17850214
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens Activity = 5 % 17850214
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens Activity = 3 % 17850214
NPT1430 Individual Protein Serine/threonine-protein kinase AKT2 Homo sapiens Activity = 17 % 17850214
NPT1430 Individual Protein Serine/threonine-protein kinase AKT2 Homo sapiens Activity = 2 % 17850214
NPT182 Individual Protein Protein kinase C alpha Homo sapiens Activity = 73 % 17850214
NPT182 Individual Protein Protein kinase C alpha Homo sapiens Activity = 29 % 17850214
NPT3455 Individual Protein Protein kinase C zeta Homo sapiens Activity = 82 % 17850214
NPT3455 Individual Protein Protein kinase C zeta Homo sapiens Activity = 66 % 17850214
NPT3364 Individual Protein Protein kinase C mu Homo sapiens Activity = 63 % 17850214
NPT3364 Individual Protein Protein kinase C mu Homo sapiens Activity = 23 % 17850214
NPT1705 Individual Protein Ribosomal protein S6 kinase alpha 3 Homo sapiens Activity = 74 % 17850214
NPT1705 Individual Protein Ribosomal protein S6 kinase alpha 3 Homo sapiens Activity = 27 % 17850214
NPT1611 Individual Protein Ribosomal protein S6 kinase 1 Homo sapiens Activity = 88 % 17850214
NPT1611 Individual Protein Ribosomal protein S6 kinase 1 Homo sapiens Activity = 32 % 17850214
NPT1448 Individual Protein Serine/threonine-protein kinase Sgk1 Homo sapiens Activity = 78 % 17850214
NPT1448 Individual Protein Serine/threonine-protein kinase Sgk1 Homo sapiens Activity = 53 % 17850214
NPT2626 Individual Protein Myosin light chain kinase, smooth muscle Homo sapiens Activity = 69 % 17850214
NPT2626 Individual Protein Myosin light chain kinase, smooth muscle Homo sapiens Activity = 27 % 17850214
NPT3813 Individual Protein Tyrosine-protein kinase SRC Gallus gallus Activity = 91 % 17850214
NPT3813 Individual Protein Tyrosine-protein kinase SRC Gallus gallus Activity = 86 % 17850214
NPT3291 Individual Protein Serine/threonine-protein kinase SRPK1 Homo sapiens Activity = 92 % 17850214
NPT3291 Individual Protein Serine/threonine-protein kinase SRPK1 Homo sapiens Activity = 91 % 17850214
NPT2 Others Unspecified Activity = 84 % 17850214
NPT2 Others Unspecified Activity = 67 % 17850214
NPT1433 Individual Protein Serine/threonine-protein kinase Aurora-B Homo sapiens Activity = 81 % 17850214
NPT1433 Individual Protein Serine/threonine-protein kinase Aurora-B Homo sapiens Activity = 80 % 17850214
NPT3206 Individual Protein Serine/threonine-protein kinase Aurora-C Homo sapiens Activity = 100 % 17850214
NPT3206 Individual Protein Serine/threonine-protein kinase Aurora-C Homo sapiens Activity = 92 % 17850214
NPT3344 Individual Protein BR serine/threonine-protein kinase 2 Homo sapiens Activity = 88 % 17850214
NPT3344 Individual Protein BR serine/threonine-protein kinase 2 Homo sapiens Activity = 79 % 17850214
NPT3232 Individual Protein CaM kinase I alpha Homo sapiens Activity = 89 % 17850214
NPT3232 Individual Protein CaM kinase I alpha Homo sapiens Activity = 77 % 17850214
NPT3248 Individual Protein CaM-kinase kinase alpha Homo sapiens Activity = 112 % 17850214
NPT3248 Individual Protein CaM-kinase kinase alpha Homo sapiens Activity = 117 % 17850214
NPT1678 Individual Protein CaM-kinase kinase beta Homo sapiens Activity = 83 % 17850214
NPT1678 Individual Protein CaM-kinase kinase beta Homo sapiens Activity = 63 % 17850214
NPT3814 Protein Complex Cyclin-dependent kinase 2/cyclin A Homo sapiens Activity = 82 % 17850214
NPT3814 Protein Complex Cyclin-dependent kinase 2/cyclin A Homo sapiens Activity = 31 % 17850214
NPT1608 Individual Protein Serine/threonine-protein kinase Chk1 Homo sapiens Activity = 100 % 17850214
NPT1608 Individual Protein Serine/threonine-protein kinase Chk1 Homo sapiens Activity = 99 % 17850214
NPT1680 Individual Protein Serine/threonine-protein kinase Chk2 Homo sapiens Activity = 94 % 17850214
NPT1680 Individual Protein Serine/threonine-protein kinase Chk2 Homo sapiens Activity = 95 % 17850214
NPT3266 Individual Protein Casein kinase I delta Homo sapiens Activity = 95 % 17850214
NPT3266 Individual Protein Casein kinase I delta Homo sapiens Activity = 74 % 17850214
NPT1609 Protein Complex Casein kinase II Homo sapiens Activity = 96 % 17850214
NPT1609 Protein Complex Casein kinase II Homo sapiens Activity = 90 % 17850214
NPT3113 Individual Protein Tyrosine-protein kinase CSK Homo sapiens Activity = 99 % 17850214
NPT3113 Individual Protein Tyrosine-protein kinase CSK Homo sapiens Activity = 93 % 17850214
NPT3114 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A Homo sapiens Activity = 10 % 17850214
NPT3114 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A Homo sapiens Activity = 7 % 17850214
NPT3399 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 2 Homo sapiens Activity = 79 % 17850214
NPT3399 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 2 Homo sapiens Activity = 26 % 17850214
NPT3460 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 3 Homo sapiens Activity = 41 % 17850214
NPT3460 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 3 Homo sapiens Activity = 8 % 17850214
NPT1344 Individual Protein Serine/threonine-protein kinase EEF2K Homo sapiens Activity = 93 % 17850214
NPT1344 Individual Protein Serine/threonine-protein kinase EEF2K Homo sapiens Activity = 94 % 17850214
NPT281 Individual Protein MAP kinase ERK1 Homo sapiens Activity = 77 % 17850214
NPT281 Individual Protein MAP kinase ERK1 Homo sapiens Activity = 59 % 17850214
NPT282 Individual Protein MAP kinase ERK2 Homo sapiens Activity = 78 % 17850214
NPT282 Individual Protein MAP kinase ERK2 Homo sapiens Activity = 64 % 17850214
NPT3363 Individual Protein Mitogen-activated protein kinase 15 Homo sapiens Activity = 61 % 17850214
NPT3363 Individual Protein Mitogen-activated protein kinase 15 Homo sapiens Activity = 28 % 17850214
NPT591 Individual Protein Glycogen synthase kinase-3 beta Homo sapiens Activity = 81 % 17850214
NPT591 Individual Protein Glycogen synthase kinase-3 beta Homo sapiens Activity = 33 % 17850214
NPT1658 Individual Protein Serine/threonine-protein kinase NEK2 Homo sapiens Activity = 101 % 17850214
NPT1658 Individual Protein Serine/threonine-protein kinase NEK2 Homo sapiens Activity = 95 % 17850214
NPT1657 Individual Protein Serine/threonine-protein kinase NEK6 Homo sapiens Activity = 95 % 17850214
NPT3284 Individual Protein Serine/threonine-protein kinase NEK7 Homo sapiens Activity = 86 % 17850214
NPT3284 Individual Protein Serine/threonine-protein kinase NEK7 Homo sapiens Activity = 84 % 17850214
NPT283 Individual Protein MAP kinase p38 alpha Homo sapiens Activity = 131 % 17850214
NPT283 Individual Protein MAP kinase p38 alpha Homo sapiens Activity = 92 % 17850214
NPT1616 Individual Protein MAP kinase p38 beta Homo sapiens Activity = 114 % 17850214
NPT1616 Individual Protein MAP kinase p38 beta Homo sapiens Activity = 105 % 17850214
NPT3432 Individual Protein Homeodomain-interacting protein kinase 2 Homo sapiens Activity = 73 % 17850214
NPT3432 Individual Protein Homeodomain-interacting protein kinase 2 Homo sapiens Activity = 24 % 17850214
NPT3409 Individual Protein Homeodomain-interacting protein kinase 3 Homo sapiens Activity = 90 % 17850214
NPT3409 Individual Protein Homeodomain-interacting protein kinase 3 Homo sapiens Activity = 71 % 17850214
NPT981 Individual Protein Inhibitor of nuclear factor kappa B kinase beta subunit Homo sapiens Activity = 93 % 17850214
NPT981 Individual Protein Inhibitor of nuclear factor kappa B kinase beta subunit Homo sapiens Activity = 89 % 17850214
NPT1426 Individual Protein c-Jun N-terminal kinase 1 Homo sapiens Activity = 89 % 17850214
NPT1426 Individual Protein c-Jun N-terminal kinase 1 Homo sapiens Activity = 90 % 17850214
NPT1427 Individual Protein c-Jun N-terminal kinase 2 Homo sapiens Activity = 94 % 17850214
NPT1427 Individual Protein c-Jun N-terminal kinase 2 Homo sapiens Activity = 78 % 17850214
NPT3207 Individual Protein c-Jun N-terminal kinase 3 Homo sapiens Activity = 81 % 17850214
NPT3207 Individual Protein c-Jun N-terminal kinase 3 Homo sapiens Activity = 86 % 17850214
NPT3815 Individual Protein Tyrosine-protein kinase LCK Mus musculus Activity = 97 % 17850214
NPT1441 Individual Protein MAP kinase-activated protein kinase 2 Homo sapiens Activity = 92 % 17850214
NPT1441 Individual Protein MAP kinase-activated protein kinase 2 Homo sapiens Activity = 73 % 17850214
NPT3461 Individual Protein MAP kinase-activated protein kinase 3 Homo sapiens Activity = 91 % 17850214
NPT3461 Individual Protein MAP kinase-activated protein kinase 3 Homo sapiens Activity = 96 % 17850214
NPT3280 Individual Protein Serine/threonine-protein kinase c-TAK1 Homo sapiens Activity = 100 % 17850214
NPT3280 Individual Protein Serine/threonine-protein kinase c-TAK1 Homo sapiens Activity = 83 % 17850214
NPT3282 Individual Protein Maternal embryonic leucine zipper kinase Homo sapiens Activity = 96 % 17850214
NPT3282 Individual Protein Maternal embryonic leucine zipper kinase Homo sapiens Activity = 63 % 17850214
NPT491 Individual Protein Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens Activity = 84 % 17850214
NPT491 Individual Protein Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens Activity = 67 % 17850214
NPT3283 Individual Protein MAP kinase-interacting serine/threonine-protein kinase MNK1 Homo sapiens Activity = 120 % 17850214
NPT3283 Individual Protein MAP kinase-interacting serine/threonine-protein kinase MNK1 Homo sapiens Activity = 109 % 17850214
NPT3213 Individual Protein MAP kinase signal-integrating kinase 2 Homo sapiens Activity = 97 % 17850214
NPT3213 Individual Protein MAP kinase signal-integrating kinase 2 Homo sapiens Activity = 80 % 17850214
NPT1613 Individual Protein Ribosomal protein S6 kinase alpha 5 Homo sapiens Activity = 19 % 17850214
NPT1613 Individual Protein Ribosomal protein S6 kinase alpha 5 Homo sapiens Activity = 9 % 17850214
NPT3331 Individual Protein Serine/threonine-protein kinase MST2 Homo sapiens Activity = 76 % 17850214
NPT3331 Individual Protein Serine/threonine-protein kinase MST2 Homo sapiens Activity = 29 % 17850214
NPT831 Individual Protein Serine/threonine-protein kinase PLK1 Homo sapiens Activity = 89 % 17850214
NPT831 Individual Protein Serine/threonine-protein kinase PLK1 Homo sapiens Activity = 80 % 17850214
NPT1612 Individual Protein MAP kinase-activated protein kinase 5 Homo sapiens Activity = 107 % 17850214
NPT3357 Individual Protein Protein kinase N2 Homo sapiens Activity = 17 % 17850214
NPT3357 Individual Protein Protein kinase N2 Homo sapiens Activity = 2 % 17850214
NPT3107 Individual Protein Rho-associated protein kinase 2 Homo sapiens Activity = 48 % 17850214
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens IC50 = 0.16 nM 19497644
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens Ki = 0.16 nM 19465931
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens IC50 = 2.5 nM 19465931
NPT1430 Individual Protein Serine/threonine-protein kinase AKT2 Homo sapiens IC50 = 30 nM 19465931
NPT2546 Individual Protein Serine/threonine-protein kinase AKT3 Homo sapiens IC50 = 51 nM 19465931
NPT2729 Individual Protein Tyrosine-protein kinase ABL Homo sapiens Inhibition = 4 % 19465931
NPT2 Others Unspecified Inhibition = 1 % 19465931
NPT2 Others Unspecified Inhibition = 4 % 19465931
NPT2 Others Unspecified Inhibition = 5 % 19465931
NPT2 Others Unspecified Inhibition = 9 % 19465931
NPT3214 Individual Protein Tyrosine-protein kinase ABL2 Homo sapiens Inhibition = 6 % 19465931
NPT3293 Individual Protein Activin receptor type-1B Homo sapiens Inhibition = 0 % 19465931
NPT4031 Individual Protein G-protein coupled receptor kinase 2 Homo sapiens Inhibition = 4 % 19465931
NPT5020 Individual Protein Beta-adrenergic receptor kinase 2 Homo sapiens Inhibition = 1 % 19465931
NPT728 Individual Protein Serine/threonine-protein kinase AKT Homo sapiens Inhibition = 100 % 19465931
NPT1430 Individual Protein Serine/threonine-protein kinase AKT2 Homo sapiens Inhibition = 94 % 19465931
NPT2546 Individual Protein Serine/threonine-protein kinase AKT3 Homo sapiens Inhibition = 99 % 19465931
NPT1661 Individual Protein ALK tyrosine kinase receptor Homo sapiens Inhibition = 17 % 19465931
NPT4091 Protein Complex AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1 Homo sapiens Inhibition = 57 % 19465931
NPT1432 Individual Protein Serine/threonine-protein kinase Aurora-A Homo sapiens Inhibition = 9 % 19465931
NPT1433 Individual Protein Serine/threonine-protein kinase Aurora-B Homo sapiens Inhibition = 17 % 19465931
NPT3312 Individual Protein Tyrosine-protein kinase BLK Homo sapiens Inhibition = 9 % 19465931
NPT2750 Individual Protein Tyrosine-protein kinase BMX Homo sapiens Inhibition = -2 % 19465931
NPT1434 Individual Protein Serine/threonine-protein kinase B-raf Homo sapiens Inhibition = 72 % 19465931
NPT2 Others Unspecified Inhibition = 45 % 19465931
NPT3315 Individual Protein BR serine/threonine-protein kinase 1 Homo sapiens Inhibition = 24 % 19465931
NPT833 Individual Protein Tyrosine-protein kinase BTK Homo sapiens Inhibition = 4 % 19465931
NPT1672 Individual Protein CaM kinase I delta Homo sapiens Inhibition = 29 % 19465931
NPT1674 Individual Protein CaM kinase II alpha Homo sapiens Inhibition = 80 % 19465931
NPT1630 Individual Protein CaM kinase II beta Homo sapiens Inhibition = 65 % 19465931
NPT1675 Individual Protein CaM kinase II delta Homo sapiens Inhibition = 90 % 19465931
NPT1677 Individual Protein CaM kinase IV Homo sapiens Inhibition = 9 % 19465931
NPT3329 Individual Protein Serine/threonine-protein kinase MRCK-A Homo sapiens Inhibition = 93 % 19465931
NPT3330 Individual Protein Serine/threonine-protein kinase MRCK beta Homo sapiens Inhibition = 94 % 19465931
NPT1570 Protein Complex Cyclin-dependent kinase 1/cyclin B Homo sapiens Inhibition = 81 % 19465931
NPT3814 Protein Complex Cyclin-dependent kinase 2/cyclin A Homo sapiens Inhibition = 85 % 19465931
NPT1509 Protein Complex Cyclin-dependent kinase 5/CDK5 activator 1 Homo sapiens Inhibition = 85 % 19465931
NPT1608 Individual Protein Serine/threonine-protein kinase Chk1 Homo sapiens Inhibition = 4 % 19465931
NPT1681 Individual Protein Dual specificty protein kinase CLK1 Homo sapiens Inhibition = 99 % 19465931
NPT1682 Individual Protein Dual specificity protein kinase CLK2 Homo sapiens Inhibition = 97 % 19465931
NPT1683 Individual Protein Dual specificity protein kinase CLK3 Homo sapiens Inhibition = 92 % 19465931
NPT3267 Individual Protein Macrophage colony stimulating factor receptor Homo sapiens Inhibition = 5 % 19465931
NPT3113 Individual Protein Tyrosine-protein kinase CSK Homo sapiens Inhibition = -1 % 19465931
NPT3168 Individual Protein Casein kinase I alpha Homo sapiens Inhibition = 18 % 19465931
NPT3266 Individual Protein Casein kinase I delta Homo sapiens Inhibition = 32 % 19465931
NPT3226 Individual Protein Casein kinase I epsilon Homo sapiens Inhibition = 42 % 19465931
NPT1684 Individual Protein Casein kinase I gamma 1 Homo sapiens Inhibition = 62 % 19465931
NPT1685 Individual Protein Casein kinase I gamma 2 Homo sapiens Inhibition = 81 % 19465931
NPT1686 Individual Protein Casein kinase I isoform gamma-3 Homo sapiens Inhibition = 57 % 19465931
NPT1598 Individual Protein Casein kinase II alpha Homo sapiens Inhibition = 2 % 19465931
NPT3273 Individual Protein Casein kinase II alpha (prime) Homo sapiens Inhibition = 6 % 19465931
NPT1687 Individual Protein Death-associated protein kinase 3 Homo sapiens Inhibition = 32 % 19465931
NPT3336 Individual Protein Serine/threonine-protein kinase DCLK2 Homo sapiens Inhibition = 11 % 19465931
NPT3114 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A Homo sapiens Inhibition = 102 % 19465931
NPT3274 Individual Protein Dual specificity tyrosine-phosphorylation-regulated kinase 1B Homo sapiens Inhibition = 99 % 19465931
NPT3460 Individual Protein Dual-specificity tyrosine-phosphorylation regulated kinase 3 Homo sapiens Inhibition = 96 % 19465931
NPT3459 Individual Protein Dual specificity tyrosine-phosphorylation-regulated kinase 4 Homo sapiens Inhibition = 30 % 19465931
NPT285 Individual Protein Epidermal growth factor receptor erbB1 Homo sapiens Inhibition = -5 % 19465931
NPT3375 Protein Family Epidermal growth factor receptor Homo sapiens Inhibition = 6 % 19465931
NPT3375 Protein Family Epidermal growth factor receptor Homo sapiens Inhibition = -3 % 19465931
NPT3354 Individual Protein Ephrin type-A receptor 1 Homo sapiens Inhibition = -1 % 19465931
NPT3225 Individual Protein Ephrin type-A receptor 2 Homo sapiens Inhibition = 8 % 19465931
NPT3217 Individual Protein Ephrin type-A receptor 3 Homo sapiens Inhibition = -5 % 19465931
NPT3218 Individual Protein Ephrin type-A receptor 4 Homo sapiens Inhibition = -4 % 19465931
NPT3219 Individual Protein Ephrin type-A receptor 5 Homo sapiens Inhibition = 1 % 19465931
NPT3216 Individual Protein Ephrin type-A receptor 8 Homo sapiens Inhibition = 3 % 19465931
NPT3212 Individual Protein Ephrin type-B receptor 1 Homo sapiens Inhibition = 1 % 19465931
NPT2941 Individual Protein Ephrin type-B receptor 2 Homo sapiens Inhibition = 1 % 19465931
NPT3359 Individual Protein Ephrin type-B receptor 3 Homo sapiens Inhibition = 2 % 19465931
NPT2572 Individual Protein Ephrin type-B receptor 4 Homo sapiens Inhibition = 16 % 19465931
NPT286 Individual Protein Receptor protein-tyrosine kinase erbB-2 Homo sapiens Inhibition = -6 % 19465931
NPT1435 Individual Protein Receptor protein-tyrosine kinase erbB-4 Homo sapiens Inhibition = -1 % 19465931
NPT3244 Individual Protein Tyrosine-protein kinase FER Homo sapiens Inhibition = 14 % 19465931
NPT1437 Individual Protein Tyrosine-protein kinase FES Homo sapiens Inhibition = 40 % 19465931
NPT1480 Individual Protein Fibroblast growth factor receptor 1 Homo sapiens Inhibition = 14 % 19465931
NPT1481 Individual Protein Fibroblast growth factor receptor 2 Homo sapiens Inhibition = 3 % 19465931
NPT3227 Individual Protein Fibroblast growth factor receptor 3 Homo sapiens Inhibition = -1 % 19465931
NPT2 Others Unspecified Inhibition = 8 % 19465931
NPT3372 Individual Protein Fibroblast growth factor receptor 4 Homo sapiens Inhibition = -2 % 19465931
NPT3112 Individual Protein Tyrosine-protein kinase FGR Homo sapiens Inhibition = 36 % 19465931
NPT301 Individual Protein Vascular endothelial growth factor receptor 1 Homo sapiens Inhibition = -2 % 19465931
NPT1650 Individual Protein Tyrosine-protein kinase receptor FLT3 Homo sapiens Inhibition = 89 % 19465931
NPT2 Others Unspecified Inhibition = 98 % 19465931
NPT2573 Individual Protein Vascular endothelial growth factor receptor 3 Homo sapiens Inhibition = 1 % 19465931
NPT3204 Individual Protein Tyrosine-protein kinase FRK Homo sapiens Inhibition = 6 % 19465931
NPT14 Individual Protein Tyrosine-protein kinase FYN Homo sapiens Inhibition = 28 % 19465931
NPT3447 Individual Protein G protein-coupled receptor kinase 4 Homo sapiens Inhibition = 72 % 19465931
NPT3457 Individual Protein G protein-coupled receptor kinase 5 Homo sapiens Inhibition = 46 % 19465931
NPT4088 Individual Protein G protein-coupled receptor kinase 6 Homo sapiens Inhibition = 78 % 19465931
NPT3438 Individual Protein G protein-coupled receptor kinase 7 Homo sapiens Inhibition = 102 % 19465931
NPT676 Individual Protein Glycogen synthase kinase-3 alpha Homo sapiens Inhibition = 84 % 19465931
NPT591 Individual Protein Glycogen synthase kinase-3 beta Homo sapiens Inhibition = 92 % 19465931
NPT3205 Individual Protein Tyrosine-protein kinase HCK Homo sapiens Inhibition = 8 % 19465931
NPT3444 Individual Protein Homeodomain-interacting protein kinase 1 Homo sapiens Inhibition = 68 % 19465931
NPT3439 Individual Protein Homeodomain-interacting protein kinase 4 Homo sapiens Inhibition = 75 % 19465931
NPT1438 Individual Protein Insulin-like growth factor I receptor Homo sapiens Inhibition = 5 % 19465931
NPT981 Individual Protein Inhibitor of nuclear factor kappa B kinase beta subunit Homo sapiens Inhibition = 11 % 19465931
NPT2574 Individual Protein Insulin receptor Homo sapiens Inhibition = -3 % 19465931
NPT3286 Individual Protein Insulin receptor-related protein Homo sapiens Inhibition = 1 % 19465931
NPT3425 Individual Protein Interleukin-1 receptor-associated kinase 4 Homo sapiens Inhibition = 53 % 19465931
NPT1439 Individual Protein Tyrosine-protein kinase ITK/TSK Homo sapiens Inhibition = 2 % 19465931
NPT3246 Individual Protein Tyrosine-protein kinase JAK2 Homo sapiens Inhibition = 3 % 19465931
NPT3246 Individual Protein Tyrosine-protein kinase JAK2 Homo sapiens Inhibition = -1 % 19465931
NPT1440 Individual Protein Tyrosine-protein kinase JAK3 Homo sapiens Inhibition = 1 % 19465931
NPT1478 Individual Protein Vascular endothelial growth factor receptor 2 Homo sapiens Inhibition = 16 % 19465931
NPT1479 Individual Protein Stem cell growth factor receptor Homo sapiens Inhibition = 4 % 19465931
NPT2 Others Unspecified Inhibition = 0 % 19465931
NPT13 Individual Protein Tyrosine-protein kinase LCK Homo sapiens Inhibition = 14 % 19465931
NPT3309 Individual Protein Leukocyte tyrosine kinase receptor Homo sapiens Inhibition = 35 % 19465931
NPT3111 Individual Protein Tyrosine-protein kinase Lyn Homo sapiens Inhibition = 8 % 19465931
NPT3111 Individual Protein Tyrosine-protein kinase Lyn Homo sapiens Inhibition = 7 % 19465931
NPT491 Individual Protein Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens Inhibition = 42 % 19465931
NPT1690 Individual Protein Dual specificity mitogen-activated protein kinase kinase 2 Homo sapiens Inhibition = 42 % 19465931
NPT1691 Individual Protein Dual specificity mitogen-activated protein kinase kinase 6 Homo sapiens Inhibition = 40 % 19465931
NPT2571 Individual Protein Mitogen-activated protein kinase kinase kinase 8 Homo sapiens Inhibition = 50 % 19465931
NPT3326 Individual Protein Mitogen-activated protein kinase kinase kinase 9 Homo sapiens Inhibition = 15 % 19465931
NPT3406 Individual Protein Mitogen-activated protein kinase kinase kinase kinase 2 Homo sapiens Inhibition = 98 % 19465931
NPT3316 Individual Protein Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens Inhibition = 99 % 19465931
NPT3109 Individual Protein Mitogen-activated protein kinase kinase kinase kinase 5 Homo sapiens Inhibition = 98 % 19465931
NPT282 Individual Protein MAP kinase ERK2 Homo sapiens Inhibition = 61 % 19465931
NPT1616 Individual Protein MAP kinase p38 beta Homo sapiens Inhibition = 6 % 19465931
NPT1615 Individual Protein MAP kinase p38 gamma Homo sapiens Inhibition = 24 % 19465931
NPT1614 Individual Protein MAP kinase p38 delta Homo sapiens Inhibition = 36 % 19465931
NPT283 Individual Protein MAP kinase p38 alpha Homo sapiens Inhibition = 3 % 19465931
NPT3311 Individual Protein Mitogen-activated protein kinase kinase kinase kinase 3 Homo sapiens Inhibition = 43 % 19465931
NPT1441 Individual Protein MAP kinase-activated protein kinase 2 Homo sapiens Inhibition = 3 % 19465931
NPT3461 Individual Protein MAP kinase-activated protein kinase 3 Homo sapiens Inhibition = 2 % 19465931
NPT1612 Individual Protein MAP kinase-activated protein kinase 5 Homo sapiens Inhibition = 10 % 19465931
NPT3317 Individual Protein Serine/threonine-protein kinase MARK1 Homo sapiens Inhibition = 65 % 19465931
NPT3235 Individual Protein MAP/microtubule affinity-regulating kinase 2 Homo sapiens Inhibition = 68 % 19465931
NPT3388 Individual Protein Tyrosine-protein kinase CTK Homo sapiens Inhibition = -10 % 19465931
NPT3320 Individual Protein Proto-oncogene tyrosine-protein kinase MER Homo sapiens Inhibition = 5 % 19465931
NPT1337 Individual Protein Hepatocyte growth factor receptor Homo sapiens Inhibition = 12 % 19465931
NPT3381 Individual Protein Misshapen-like kinase 1 Homo sapiens Inhibition = 98 % 19465931
NPT3390 Individual Protein Macrophage-stimulating protein receptor Homo sapiens Inhibition = 10 % 19465931
NPT1693 Individual Protein Serine/threonine-protein kinase MST4 Homo sapiens Inhibition = 88 % 19465931
NPT3333 Individual Protein Muscle, skeletal receptor tyrosine protein kinase Homo sapiens Inhibition = 6 % 19465931
NPT3243 Individual Protein myosin light chain kinase 2 Homo sapiens Inhibition = 22 % 19465931
NPT3340 Individual Protein Serine/threonine-protein kinase Nek1 Homo sapiens Inhibition = 44 % 19465931
NPT1658 Individual Protein Serine/threonine-protein kinase NEK2 Homo sapiens Inhibition = 2 % 19465931
NPT3396 Individual Protein Serine/threonine-protein kinase Nek4 Homo sapiens Inhibition = 41 % 19465931
NPT1657 Individual Protein Serine/threonine-protein kinase NEK6 Homo sapiens Inhibition = 3 % 19465931
NPT3284 Individual Protein Serine/threonine-protein kinase NEK7 Homo sapiens Inhibition = 1 % 19465931
NPT3241 Individual Protein Serine/threonine-protein kinase NEK9 Homo sapiens Inhibition = 15 % 19465931
NPT3239 Individual Protein Nerve growth factor receptor Trk-A Homo sapiens Inhibition = 42 % 19465931
NPT3270 Individual Protein Neurotrophic tyrosine kinase receptor type 2 Homo sapiens Inhibition = 12 % 19465931
NPT3271 Individual Protein NT-3 growth factor receptor Homo sapiens Inhibition = 28 % 19465931
NPT1442 Individual Protein Serine/threonine-protein kinase PAK 2 Homo sapiens Inhibition = 55 % 19465931
NPT3247 Individual Protein Serine/threonine-protein kinase PAK 3 Homo sapiens Inhibition = 45 % 19465931
NPT1695 Individual Protein Serine/threonine-protein kinase PAK 4 Homo sapiens Inhibition = 26 % 19465931
NPT1697 Individual Protein Serine/threonine-protein kinase PAK6 Homo sapiens Inhibition = 32 % 19465931
NPT1696 Individual Protein Serine/threonine-protein kinase PAK7 Homo sapiens Inhibition = 25 % 19465931
NPT3020 Individual Protein Platelet-derived growth factor receptor alpha Homo sapiens Inhibition = 1 % 19465931
NPT2 Others Unspecified Inhibition = 11 % 19465931
NPT2575 Individual Protein Platelet-derived growth factor receptor beta Homo sapiens Inhibition = 18 % 19465931
NPT1699 Individual Protein 3-phosphoinositide dependent protein kinase-1 Homo sapiens Inhibition = 88 % 19465931
NPT3224 Individual Protein Phosphorylase kinase gamma subunit 1 Homo sapiens Inhibition = 76 % 19465931
NPT3223 Individual Protein Phosphorylase kinase gamma subunit 2 Homo sapiens Inhibition = 11 % 19465931
NPT1265 Individual Protein Serine/threonine-protein kinase PIM1 Homo sapiens Inhibition = 100 % 19465931
NPT1700 Individual Protein Serine/threonine-protein kinase PIM2 Homo sapiens Inhibition = 95 % 19465931
NPT1656 Individual Protein Protein kinase N1 Homo sapiens Inhibition = 100 % 19465931
NPT831 Individual Protein Serine/threonine-protein kinase PLK1 Homo sapiens Inhibition = 1 % 19465931
NPT3414 Individual Protein Serine/threonine-protein kinase PLK2 Homo sapiens Inhibition = 6 % 19465931
NPT3358 Individual Protein Serine/threonine-protein kinase PLK3 Homo sapiens Inhibition = 7 % 19465931
NPT1703 Individual Protein cAMP-dependent protein kinase alpha-catalytic subunit Homo sapiens Inhibition = 99 % 19465931
NPT182 Individual Protein Protein kinase C alpha Homo sapiens Inhibition = 95 % 19465931
NPT760 Individual Protein Protein kinase C beta Homo sapiens Inhibition = 97 % 19465931
NPT760 Individual Protein Protein kinase C beta Homo sapiens Inhibition = 68 % 19465931
NPT881 Individual Protein Protein kinase C delta Homo sapiens Inhibition = 100 % 19465931
NPT761 Individual Protein Protein kinase C epsilon Homo sapiens Inhibition = 99 % 19465931
NPT880 Individual Protein Protein kinase C gamma Homo sapiens Inhibition = 108 % 19465931
NPT3124 Individual Protein Protein kinase C eta Homo sapiens Inhibition = 99 % 19465931
NPT3394 Individual Protein Protein kinase C iota Homo sapiens Inhibition = 10 % 19465931
NPT3366 Individual Protein Protein kinase C nu Homo sapiens Inhibition = 94 % 19465931
NPT887 Individual Protein Protein kinase C theta Homo sapiens Inhibition = 98 % 19465931
NPT3455 Individual Protein Protein kinase C zeta Homo sapiens Inhibition = 26 % 19465931
NPT3364 Individual Protein Protein kinase C mu Homo sapiens Inhibition = 97 % 19465931
NPT3365 Individual Protein Serine/threonine-protein kinase D2 Homo sapiens Inhibition = 98 % 19465931
NPT3367 Individual Protein cGMP-dependent protein kinase 1 beta Homo sapiens Inhibition = 99 % 19465931
NPT3368 Individual Protein cGMP-dependent protein kinase 2 Homo sapiens Inhibition = 96 % 19465931
NPT3262 Individual Protein Serine/threonine-protein kinase PRKX Homo sapiens Inhibition = 99 % 19465931
NPT3263 Individual Protein Protein tyrosine kinase 2 beta Homo sapiens Inhibition = 2 % 19465931
NPT3215 Individual Protein Tyrosine-protein kinase BRK Homo sapiens Inhibition = 0 % 19465931
NPT1424 Individual Protein Serine/threonine-protein kinase RAF Homo sapiens Inhibition = 81 % 19465931
NPT3370 Individual Protein Tyrosine-protein kinase receptor RET Homo sapiens Inhibition = 30 % 19465931
NPT2 Others Unspecified Inhibition = 48 % 19465931
NPT2 Others Unspecified Inhibition = 29 % 19465931
NPT592 Individual Protein Rho-associated protein kinase 1 Homo sapiens Inhibition = 99 % 19465931
NPT3107 Individual Protein Rho-associated protein kinase 2 Homo sapiens Inhibition = 100 % 19465931
NPT3373 Individual Protein Proto-oncogene tyrosine-protein kinase ROS Homo sapiens Inhibition = 17 % 19465931
NPT3106 Individual Protein Ribosomal protein S6 kinase alpha 1 Homo sapiens Inhibition = 96 % 19465931
NPT3234 Individual Protein Ribosomal protein S6 kinase alpha 2 Homo sapiens Inhibition = 85 % 19465931
NPT1705 Individual Protein Ribosomal protein S6 kinase alpha 3 Homo sapiens Inhibition = 98 % 19465931
NPT3374 Individual Protein Ribosomal protein S6 kinase alpha 4 Homo sapiens Inhibition = 97 % 19465931
NPT1613 Individual Protein Ribosomal protein S6 kinase alpha 5 Homo sapiens Inhibition = 102 % 19465931
NPT3254 Individual Protein Ribosomal protein S6 kinase alpha 6 Homo sapiens Inhibition = 87 % 19465931
NPT1611 Individual Protein Ribosomal protein S6 kinase 1 Homo sapiens Inhibition = 99 % 19465931
NPT1448 Individual Protein Serine/threonine-protein kinase Sgk1 Homo sapiens Inhibition = 85 % 19465931
NPT3456 Individual Protein Serine/threonine-protein kinase Sgk2 Homo sapiens Inhibition = 89 % 19465931
NPT3418 Individual Protein Serine/threonine-protein kinase Sgk3 Homo sapiens Inhibition = 78 % 19465931
NPT36 Individual Protein Tyrosine-protein kinase SRC Homo sapiens Inhibition = 11 % 19465931
NPT36 Individual Protein Tyrosine-protein kinase SRC Homo sapiens Inhibition = 5 % 19465931
NPT3350 Individual Protein Tyrosine-protein kinase Srms Homo sapiens Inhibition = -1 % 19465931
NPT3291 Individual Protein Serine/threonine-protein kinase SRPK1 Homo sapiens Inhibition = 27 % 19465931
NPT3292 Individual Protein Serine/threonine-protein kinase SRPK2 Homo sapiens Inhibition = 39 % 19465931
NPT3462 Individual Protein Testis-specific serine/threonine-protein kinase 2 Homo sapiens Inhibition = 4 % 19465931
NPT3299 Individual Protein Testis-specific serine/threonine-protein kinase 1 Homo sapiens Inhibition = 71 % 19465931
NPT3419 Individual Protein Serine/threonine-protein kinase SRPK3 Homo sapiens Inhibition = 3 % 19465931
NPT3332 Individual Protein Serine/threonine-protein kinase 24 Homo sapiens Inhibition = 76 % 19465931
NPT1717 Individual Protein Serine/threonine-protein kinase 25 Homo sapiens Inhibition = 102 % 19465931
NPT3331 Individual Protein Serine/threonine-protein kinase MST2 Homo sapiens Inhibition = 93 % 19465931
NPT1711 Individual Protein Serine/threonine-protein kinase MST1 Homo sapiens Inhibition = 90 % 19465931
NPT1432 Individual Protein Serine/threonine-protein kinase Aurora-A Homo sapiens Inhibition = 16 % 19465931
NPT1449 Individual Protein Tyrosine-protein kinase SYK Homo sapiens Inhibition = 0 % 19465931
NPT3426 Individual Protein Serine/threonine-protein kinase TAO2 Homo sapiens Inhibition = 35 % 19465931
NPT3417 Individual Protein Serine/threonine-protein kinase TBK1 Homo sapiens Inhibition = 39 % 19465931
NPT2576 Individual Protein Tyrosine-protein kinase TIE-2 Homo sapiens Inhibition = -1 % 19465931
NPT3277 Individual Protein Tyrosine-protein kinase receptor TYRO3 Homo sapiens Inhibition = 14 % 19465931
NPT1663 Individual Protein Tyrosine-protein kinase YES Homo sapiens Inhibition = 20 % 19465931
NPT3259 Individual Protein Tyrosine-protein kinase ZAP-70 Homo sapiens Inhibition = 11 % 19465931
NPT3454 Individual Protein PAS domain-containing serine/threonine-protein kinase Homo sapiens Inhibition = 36 % 19465931
NPT532 Individual Protein Lysine-specific demethylase 4A Homo sapiens Potency 35481.3 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 8199.5 nM PubChem BioAssay data set
NPT152 Individual Protein Nuclear factor erythroid 2-related factor 2 Homo sapiens Potency 5173.5 nM PubChem BioAssay data set
NPT198 Individual Protein Vitamin D receptor Homo sapiens Potency 2511.9 nM PubChem BioAssay data set
NPT803 Individual Protein Flap endonuclease 1 Homo sapiens Potency 44668.4 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 794.3 nM PubChem BioAssay data set
NPT65 Cell Line HepG2 Homo sapiens Potency 4466.8 nM PubChem BioAssay data set
NPT154 Individual Protein Mothers against decapentaplegic homolog 3 Homo sapiens Potency 1000 nM PubChem BioAssay data set
NPT2 Others Unspecified AC50 = 7400 nM PubChem BioAssay data set
NPT2 Others Unspecified AC50 = 1770 nM PubChem BioAssay data set
NPT2 Others Unspecified AC50 = 2850 nM PubChem BioAssay data set
NPT10 Individual Protein Geminin Homo sapiens Potency 2310.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 3548.1 nM PubChem BioAssay data set
NPT10 Individual Protein Geminin Homo sapiens Potency 580.5 nM PubChem BioAssay data set
NPT478 Individual Protein Ataxin-2 Homo sapiens Potency 11220.2 nM PubChem BioAssay data set
NPT101 Individual Protein Glucagon-like peptide 1 receptor Homo sapiens Potency 501.2 nM PubChem BioAssay data set
NPT1043 Individual Protein Glycoprotein hormones alpha chain Homo sapiens Potency 2511.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 580.5 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 10322.5 nM PubChem BioAssay data set
NPT861 Individual Protein Isocitrate dehydrogenase [NADP] cytoplasmic Homo sapiens Potency 18356.4 nM PubChem BioAssay data set
NPT1899 Cell Line DSH1 Homo sapiens IC50 = 360.93 nM 10.6019/CHEMBL1201861
NPT464 Cell Line Daudi Homo sapiens IC50 = 354.63 nM 10.6019/CHEMBL1201861
NPT1900 Cell Line DU-4475 Homo sapiens IC50 = 800.63 nM 10.6019/CHEMBL1201861
NPT4601 Cell Line EHEB Homo sapiens IC50 = 402.1 nM 10.6019/CHEMBL1201861
NPT394 Cell Line EKVX Homo sapiens IC50 = 2565.65 nM 10.6019/CHEMBL1201861
NPT1901 Cell Line EM-2 Homo sapiens IC50 = 583.37 nM 10.6019/CHEMBL1201861
NPT1902 Cell Line ES1 Homo sapiens IC50 = 739.09 nM 10.6019/CHEMBL1201861
NPT1905 Cell Line ES4 Homo sapiens IC50 = 37.74 nM 10.6019/CHEMBL1201861
NPT1903 Cell Line ES5 Homo sapiens IC50 = 8012.92 nM 10.6019/CHEMBL1201861
NPT1904 Cell Line ES3 Homo sapiens IC50 = 3472.04 nM 10.6019/CHEMBL1201861
NPT1906 Cell Line EB-3 Homo sapiens IC50 = 334.39 nM 10.6019/CHEMBL1201861
NPT1907 Cell Line EB2 Homo sapiens IC50 = 9151.13 nM 10.6019/CHEMBL1201861
NPT1908 Cell Line EC-GI-10 Homo sapiens IC50 = 2457.56 nM 10.6019/CHEMBL1201861
NPT1910 Cell Line ECC4 Homo sapiens IC50 = 29058.82 nM 10.6019/CHEMBL1201861
NPT376 Cell Line A498 Homo sapiens IC50 = 68046 nM 10.6019/CHEMBL1201861
NPT1912 Cell Line COLO-800 Homo sapiens IC50 = 217220.72 nM 10.6019/CHEMBL1201861
NPT1189 Cell Line DG-75 Homo sapiens IC50 = 545.85 nM 10.6019/CHEMBL1201861
NPT1913 Cell Line DJM-1 Homo sapiens IC50 = 331.16 nM 10.6019/CHEMBL1201861
NPT2280 Cell Line A704 Homo sapiens IC50 = 260.96 nM 10.6019/CHEMBL1201861
NPT1911 Cell Line C2BBe1 Homo sapiens IC50 = 2073.22 nM 10.6019/CHEMBL1201861
NPT1914 Cell Line COLO-824 Homo sapiens IC50 = 3301.5 nM 10.6019/CHEMBL1201861
NPT1915 Cell Line COLO-829 Homo sapiens IC50 = 14469.99 nM 10.6019/CHEMBL1201861
NPT576 Cell Line DMS-114 Homo sapiens IC50 = 983.34 nM 10.6019/CHEMBL1201861
NPT1916 Cell Line ACN Homo sapiens IC50 = 908.85 nM 10.6019/CHEMBL1201861
NPT1452 Cell Line C8166 Homo sapiens IC50 = 52733.03 nM 10.6019/CHEMBL1201861
NPT1917 Cell Line CA46 Homo sapiens IC50 = 2065.98 nM 10.6019/CHEMBL1201861
NPT1918 Cell Line DMS-79 Homo sapiens IC50 = 750.46 nM 10.6019/CHEMBL1201861
NPT1919 Cell Line DOHH-2 Homo sapiens IC50 = 240.02 nM 10.6019/CHEMBL1201861
NPT1920 Cell Line ALL-PO Homo sapiens IC50 = 796.71 nM 10.6019/CHEMBL1201861
NPT1921 Cell Line COR-L279 Homo sapiens IC50 = 569.81 nM 10.6019/CHEMBL1201861
NPT1922 Cell Line COR-L88 Homo sapiens IC50 = 737.55 nM 10.6019/CHEMBL1201861
NPT1923 Cell Line DMS-153 Homo sapiens IC50 = 668.56 nM 10.6019/CHEMBL1201861
NPT1924 Cell Line AM-38 Homo sapiens IC50 = 18566.32 nM 10.6019/CHEMBL1201861
NPT1925 Cell Line CAL-148 Homo sapiens IC50 = 88.25 nM 10.6019/CHEMBL1201861
NPT1926 Cell Line CP66-MEL Homo sapiens IC50 = 459.12 nM 10.6019/CHEMBL1201861
NPT1927 Cell Line ARH-77 Homo sapiens IC50 = 297.72 nM 10.6019/CHEMBL1201861
NPT1928 Cell Line ATN-1 Homo sapiens IC50 = 1923.05 nM 10.6019/CHEMBL1201861
NPT5021 Cell Line CP67-MEL Homo sapiens IC50 = 312.73 nM 10.6019/CHEMBL1201861
NPT1929 Cell Line CPC-N Homo sapiens IC50 = 303.67 nM 10.6019/CHEMBL1201861
NPT1930 Cell Line CTB-1 Homo sapiens IC50 = 508.66 nM 10.6019/CHEMBL1201861
NPT1932 Cell Line CTV-1 Homo sapiens IC50 = 323.24 nM 10.6019/CHEMBL1201861
NPT1933 Cell Line CW-2 Homo sapiens IC50 = 145549.47 nM 10.6019/CHEMBL1201861
NPT1094 Cell Line 697 Homo sapiens IC50 = 32.81 nM 10.6019/CHEMBL1201861
NPT1931 Cell Line BB30-HNC Homo sapiens IC50 = 219.63 nM 10.6019/CHEMBL1201861
NPT1934 Cell Line BB49-HNC Homo sapiens IC50 = 3026.19 nM 10.6019/CHEMBL1201861
NPT1935 Cell Line BB65-RCC Homo sapiens IC50 = 597.14 nM 10.6019/CHEMBL1201861
NPT929 Cell Line BC1 cell line IC50 = 700.83 nM 10.6019/CHEMBL1201861
NPT1937 Cell Line CAS-1 Homo sapiens IC50 = 2796.38 nM 10.6019/CHEMBL1201861
NPT1939 Cell Line 8-MG-BA Homo sapiens IC50 = 163.01 nM 10.6019/CHEMBL1201861
NPT1936 Cell Line BC-3 Homo sapiens IC50 = 342.35 nM 10.6019/CHEMBL1201861
NPT1940 Cell Line BE-13 Homo sapiens IC50 = 502.24 nM 10.6019/CHEMBL1201861
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 143.88 nM 10.6019/CHEMBL1201861
NPT1938 Cell Line Calu-6 Homo sapiens IC50 = 137.42 nM 10.6019/CHEMBL1201861
NPT1941 Cell Line A101D Homo sapiens IC50 = 132.65 nM 10.6019/CHEMBL1201861
NPT1942 Cell Line CESS Homo sapiens IC50 = 191.24 nM 10.6019/CHEMBL1201861
NPT1943 Cell Line CGTH-W-1 Homo sapiens IC50 = 245.66 nM 10.6019/CHEMBL1201861
NPT1944 Cell Line D-247MG Homo sapiens IC50 = 973.71 nM 10.6019/CHEMBL1201861
NPT1945 Cell Line CHP-126 Homo sapiens IC50 = 267.36 nM 10.6019/CHEMBL1201861
NPT1946 Cell Line D-263MG Homo sapiens IC50 = 4108.51 nM 10.6019/CHEMBL1201861
NPT1947 Cell Line D283 Med IC50 = 96497.78 nM 10.6019/CHEMBL1201861
NPT1948 Cell Line A253 cell line IC50 = 392.62 nM 10.6019/CHEMBL1201861
NPT1949 Cell Line BL-41 Homo sapiens IC50 = 96.35 nM 10.6019/CHEMBL1201861
NPT1950 Cell Line BL-70 Homo sapiens IC50 = 57.03 nM 10.6019/CHEMBL1201861
NPT1951 Cell Line CMK Homo sapiens IC50 = 275.47 nM 10.6019/CHEMBL1201861
NPT1953 Cell Line D-336MG Homo sapiens IC50 = 421.44 nM 10.6019/CHEMBL1201861
NPT1955 Cell Line A3-KAW Homo sapiens IC50 = 196.23 nM 10.6019/CHEMBL1201861
NPT4606 Cell Line BOKU Homo sapiens IC50 = 3092.02 nM 10.6019/CHEMBL1201861
NPT1952 Cell Line COLO-320-HSR Homo sapiens IC50 = 937.47 nM 10.6019/CHEMBL1201861
NPT1956 Cell Line COLO-668 Homo sapiens IC50 = 405.44 nM 10.6019/CHEMBL1201861
NPT1957 Cell Line D-502MG Homo sapiens IC50 = 3279.65 nM 10.6019/CHEMBL1201861
NPT1958 Cell Line A388 Homo sapiens IC50 = 84.33 nM 10.6019/CHEMBL1201861
NPT1959 Cell Line A4-Fuk Homo sapiens IC50 = 102.54 nM 10.6019/CHEMBL1201861
NPT845 Cell Line BT-474 Homo sapiens IC50 = 584.44 nM 10.6019/CHEMBL1201861
NPT1960 Cell Line BV-173 Homo sapiens IC50 = 268.78 nM 10.6019/CHEMBL1201861
NPT1962 Cell Line DB Homo sapiens IC50 = 374.8 nM 10.6019/CHEMBL1201861
NPT1963 Cell Line Becker Homo sapiens IC50 = 303.17 nM 10.6019/CHEMBL1201861
NPT1964 Cell Line COLO-684 Homo sapiens IC50 = 79.47 nM 10.6019/CHEMBL1201861
NPT1965 Cell Line DEL Homo sapiens IC50 = 231.45 nM 10.6019/CHEMBL1201861
NPT1966 Cell Line NCI-H1838 Homo sapiens IC50 = 8262.59 nM 10.6019/CHEMBL1201861
NPT639 Cell Line NCI-H187 Homo sapiens IC50 = 464.04 nM 10.6019/CHEMBL1201861
NPT1967 Cell Line NCI-H526 Homo sapiens IC50 = 1658.12 nM 10.6019/CHEMBL1201861
NPT1968 Cell Line OMC-1 Homo sapiens IC50 = 190.9 nM 10.6019/CHEMBL1201861
NPT389 Cell Line RPMI-8226 Homo sapiens IC50 = 670.14 nM 10.6019/CHEMBL1201861
NPT926 Cell Line SK-MEL-1 Homo sapiens IC50 = 41406.34 nM 10.6019/CHEMBL1201861
NPT1969 Cell Line TGW Homo sapiens IC50 = 569.42 nM 10.6019/CHEMBL1201861
NPT1970 Cell Line THP-1 Homo sapiens IC50 = 43012.34 nM 10.6019/CHEMBL1201861
NPT1971 Cell Line GI-1 Homo sapiens IC50 = 187.46 nM 10.6019/CHEMBL1201861
NPT1972 Cell Line GI-ME-N Homo sapiens IC50 = 278.39 nM 10.6019/CHEMBL1201861
NPT116 Cell Line HL-60 Homo sapiens IC50 = 500.33 nM 10.6019/CHEMBL1201861
NPT1973 Cell Line IST-SL1 Homo sapiens IC50 = 434.08 nM 10.6019/CHEMBL1201861
NPT1974 Cell Line IST-SL2 Homo sapiens IC50 = 193.69 nM 10.6019/CHEMBL1201861
NPT1975 Cell Line KS-1 Homo sapiens IC50 = 53.54 nM 10.6019/CHEMBL1201861
NPT1976 Cell Line LNCaP-Clone-FGC Homo sapiens IC50 = 18394.93 nM 10.6019/CHEMBL1201861
NPT1977 Cell Line LOUCY Homo sapiens IC50 = 157.83 nM 10.6019/CHEMBL1201861
NPT2209 Cell Line MFH-ino Homo sapiens IC50 = 235.53 nM 10.6019/CHEMBL1201861
NPT1978 Cell Line MFM-223 Homo sapiens IC50 = 3304.82 nM 10.6019/CHEMBL1201861
NPT1979 Cell Line NB13 Homo sapiens IC50 = 332.31 nM 10.6019/CHEMBL1201861
NPT1980 Cell Line NB14 Homo sapiens IC50 = 1968.79 nM 10.6019/CHEMBL1201861
NPT1981 Cell Line NCI-H1882 Homo sapiens IC50 = 428.49 nM 10.6019/CHEMBL1201861
NPT1982 Cell Line NCI-H1963 Homo sapiens IC50 = 392 nM 10.6019/CHEMBL1201861
NPT1983 Cell Line NCI-H64 Homo sapiens IC50 = 3155.58 nM 10.6019/CHEMBL1201861
NPT1984 Cell Line ONS-76 Homo sapiens IC50 = 443.96 nM 10.6019/CHEMBL1201861
NPT1986 Cell Line RPMI 8402 Homo sapiens IC50 = 183.65 nM 10.6019/CHEMBL1201861
NPT1987 Cell Line RPMI-8866 Homo sapiens IC50 = 55033.61 nM 10.6019/CHEMBL1201861
NPT147 Cell Line SK-MEL-2 Homo sapiens IC50 = 832.58 nM 10.6019/CHEMBL1201861
NPT1988 Cell Line SW684 Homo sapiens IC50 = 15906.5 nM 10.6019/CHEMBL1201861
NPT384 Cell Line TK-10 Homo sapiens IC50 = 226.08 nM 10.6019/CHEMBL1201861
NPT1989 Cell Line GOTO Homo sapiens IC50 = 366.19 nM 10.6019/CHEMBL1201861
NPT1990 Cell Line J-RT3-T3-5 Homo sapiens IC50 = 184.59 nM 10.6019/CHEMBL1201861
NPT1991 Cell Line KU812 cell line IC50 = 96.49 nM 10.6019/CHEMBL1201861
NPT1992 Cell Line KURAMOCHI Homo sapiens IC50 = 244.25 nM 10.6019/CHEMBL1201861
NPT390 Cell Line LOX IMVI Homo sapiens IC50 = 797.13 nM 10.6019/CHEMBL1201861
NPT1993 Cell Line LP-1 Homo sapiens IC50 = 34806.77 nM 10.6019/CHEMBL1201861
NPT1994 Cell Line MHH-CALL-2 Homo sapiens IC50 = 12635.65 nM 10.6019/CHEMBL1201861
NPT1995 Cell Line NB17 Homo sapiens IC50 = 112.22 nM 10.6019/CHEMBL1201861
NPT1996 Cell Line NB5 Homo sapiens IC50 = 665.12 nM 10.6019/CHEMBL1201861
NPT1396 Cell Line NCI-H69 Homo sapiens IC50 = 317.92 nM 10.6019/CHEMBL1201861
NPT1985 Cell Line OPM-2 Homo sapiens IC50 = 314.39 nM 10.6019/CHEMBL1201861
NPT1997 Cell Line OS-RC-2 Homo sapiens IC50 = 175.45 nM 10.6019/CHEMBL1201861
NPT1998 Cell Line RS4-11 Homo sapiens IC50 = 168.41 nM 10.6019/CHEMBL1201861
NPT1999 Cell Line TUR Homo sapiens IC50 = 111115.92 nM 10.6019/CHEMBL1201861
NPT2000 Cell Line GR-ST Homo sapiens IC50 = 448.37 nM 10.6019/CHEMBL1201861
NPT379 Cell Line HOP-62 Homo sapiens IC50 = 140.35 nM 10.6019/CHEMBL1201861
NPT2001 Cell Line JAR Homo sapiens IC50 = 155.61 nM 10.6019/CHEMBL1201861
NPT2002 Cell Line KY821 Homo sapiens IC50 = 246 nM 10.6019/CHEMBL1201861
NPT2003 Cell Line LS-1034 Homo sapiens IC50 = 630.03 nM 10.6019/CHEMBL1201861
NPT2004 Cell Line LS-123 Homo sapiens IC50 = 337.1 nM 10.6019/CHEMBL1201861
NPT2005 Cell Line MHH-NB-11 Homo sapiens IC50 = 2333.59 nM 10.6019/CHEMBL1201861
NPT2006 Cell Line MHH-PREB-1 Homo sapiens IC50 = 270.51 nM 10.6019/CHEMBL1201861
NPT2007 Cell Line NB6 Homo sapiens IC50 = 479.75 nM 10.6019/CHEMBL1201861
NPT2008 Cell Line NB69 Homo sapiens IC50 = 226.69 nM 10.6019/CHEMBL1201861
NPT2009 Cell Line NCI-H2081 Homo sapiens IC50 = 1258.79 nM 10.6019/CHEMBL1201861
NPT2010 Cell Line NCI-H716 Homo sapiens IC50 = 219277.05 nM 10.6019/CHEMBL1201861
NPT2011 Cell Line NCI-H719 Homo sapiens IC50 = 1936.15 nM 10.6019/CHEMBL1201861
NPT2012 Cell Line NCI-H720 Homo sapiens IC50 = 154.46 nM 10.6019/CHEMBL1201861
NPT456 Cell Line OVCAR-4 Homo sapiens IC50 = 243.27 nM 10.6019/CHEMBL1201861
NPT406 Cell Line RXF 393 Homo sapiens IC50 = 656.56 nM 10.6019/CHEMBL1201861
NPT2013 Cell Line SK-MM-2 Homo sapiens IC50 = 622.9 nM 10.6019/CHEMBL1201861
NPT2014 Cell Line SW872 Homo sapiens IC50 = 255.39 nM 10.6019/CHEMBL1201861
NPT2015 Cell Line U-266 Homo sapiens IC50 = 1821.36 nM 10.6019/CHEMBL1201861
NPT2016 Cell Line ES6 Homo sapiens IC50 = 91.53 nM 10.6019/CHEMBL1201861
NPT2017 Cell Line ES7 Homo sapiens IC50 = 77766.68 nM 10.6019/CHEMBL1201861
NPT2018 Cell Line GT3TKB Homo sapiens IC50 = 3144.33 nM 10.6019/CHEMBL1201861
NPT2019 Cell Line JVM-2 Homo sapiens IC50 = 3047.89 nM 10.6019/CHEMBL1201861
NPT2020 Cell Line JVM-3 Homo sapiens IC50 = 1478.98 nM 10.6019/CHEMBL1201861
NPT2021 Cell Line LS-411N Homo sapiens IC50 = 87.45 nM 10.6019/CHEMBL1201861
NPT2022 Cell Line LS-513 Homo sapiens IC50 = 35876.37 nM 10.6019/CHEMBL1201861
NPT2023 Cell Line NB7 Homo sapiens IC50 = 6641.85 nM 10.6019/CHEMBL1201861
NPT2024 Cell Line NCI-H209 Homo sapiens IC50 = 246.36 nM 10.6019/CHEMBL1201861
NPT2025 Cell Line NCI-H747 Homo sapiens IC50 = 82.55 nM 10.6019/CHEMBL1201861
NPT80 Cell Line Raji Homo sapiens IC50 = 380.02 nM 10.6019/CHEMBL1201861
NPT2026 Cell Line Ramos-2G6-4C10 Homo sapiens IC50 = 170.12 nM 10.6019/CHEMBL1201861
NPT2027 Cell Line SK-N-DZ Homo sapiens IC50 = 6418.84 nM 10.6019/CHEMBL1201861
NPT2029 Cell Line SW 954 Homo sapiens IC50 = 177.07 nM 10.6019/CHEMBL1201861
NPT2030 Cell Line U-698-M Homo sapiens IC50 = 13298.99 nM 10.6019/CHEMBL1201861
NPT1535 Cell Line U-87 MG Homo sapiens IC50 = 19803.88 nM 10.6019/CHEMBL1201861
NPT2031 Cell Line ES8 Homo sapiens IC50 = 151.13 nM 10.6019/CHEMBL1201861
NPT2032 Cell Line HAL-01 Homo sapiens IC50 = 10952.71 nM 10.6019/CHEMBL1201861
NPT2033 Cell Line JIYOYE Homo sapiens IC50 = 188.45 nM 10.6019/CHEMBL1201861
NPT111 Cell Line K562 Homo sapiens IC50 = 385.36 nM 10.6019/CHEMBL1201861
NPT2034 Cell Line LU-134-A Homo sapiens IC50 = 362.82 nM 10.6019/CHEMBL1201861
NPT2035 Cell Line NCCIT Homo sapiens IC50 = 234.23 nM 10.6019/CHEMBL1201861
NPT2036 Cell Line NCI-H1092 Homo sapiens IC50 = 938.39 nM 10.6019/CHEMBL1201861
NPT2037 Cell Line NCI-H2107 Homo sapiens IC50 = 958.37 nM 10.6019/CHEMBL1201861
NPT1082 Cell Line NCI-H2126 Homo sapiens IC50 = 309.18 nM 10.6019/CHEMBL1201861
NPT2038 Cell Line NCI-H748 Homo sapiens IC50 = 508.44 nM 10.6019/CHEMBL1201861
NPT2040 Cell Line P30-OHK Homo sapiens IC50 = 26740.39 nM 10.6019/CHEMBL1201861
NPT2041 Cell Line P31-FUJ Homo sapiens IC50 = 17338.73 nM 10.6019/CHEMBL1201861
NPT2028 Cell Line SK-N-FI Homo sapiens IC50 = 844.76 nM 10.6019/CHEMBL1201861
NPT2043 Cell Line SK-NEP-1 Homo sapiens IC50 = 518.67 nM 10.6019/CHEMBL1201861
NPT2044 Cell Line SW 962 Homo sapiens IC50 = 254.68 nM 10.6019/CHEMBL1201861
NPT2045 Cell Line ETK-1 Homo sapiens IC50 = 101.06 nM 10.6019/CHEMBL1201861
NPT2046 Cell Line EVSA-T Homo sapiens IC50 = 220.18 nM 10.6019/CHEMBL1201861
NPT2047 Cell Line HC-1 Homo sapiens IC50 = 207.78 nM 10.6019/CHEMBL1201861
NPT2048 Cell Line HCC1187 Homo sapiens IC50 = 1130.72 nM 10.6019/CHEMBL1201861
NPT2049 Cell Line HT Homo sapiens IC50 = 373.34 nM 10.6019/CHEMBL1201861
NPT2050 Cell Line K052 Homo sapiens IC50 = 88780.94 nM 10.6019/CHEMBL1201861
NPT2051 Cell Line K5 Homo sapiens IC50 = 427.64 nM 10.6019/CHEMBL1201861
NPT2052 Cell Line KALS-1 Homo sapiens IC50 = 203.07 nM 10.6019/CHEMBL1201861
NPT2053 Cell Line LU-139 Homo sapiens IC50 = 367.29 nM 10.6019/CHEMBL1201861
NPT2054 Cell Line LU-165 Homo sapiens IC50 = 619.95 nM 10.6019/CHEMBL1201861
NPT2055 Cell Line ML-2 Homo sapiens IC50 = 192.41 nM 10.6019/CHEMBL1201861
NPT2056 Cell Line MLMA Homo sapiens IC50 = 447.01 nM 10.6019/CHEMBL1201861
NPT2057 Cell Line NCI-H1155 Homo sapiens IC50 = 563.94 nM 10.6019/CHEMBL1201861
NPT2058 Cell Line NCI-H128 Homo sapiens IC50 = 5588.22 nM 10.6019/CHEMBL1201861
NPT2059 Cell Line NCI-H2141 Homo sapiens IC50 = 539.67 nM 10.6019/CHEMBL1201861
NPT2039 Cell Line NCI-H82 Homo sapiens IC50 = 164.22 nM 10.6019/CHEMBL1201861
NPT2061 Cell Line NCI-H889 Homo sapiens IC50 = 9788.49 nM 10.6019/CHEMBL1201861
NPT2042 Cell Line SBC-1 Homo sapiens IC50 = 160.17 nM 10.6019/CHEMBL1201861
NPT2062 Cell Line SCC-15 Homo sapiens IC50 = 4697.95 nM 10.6019/CHEMBL1201861
NPT2063 Cell Line SK-PN-DW Homo sapiens IC50 = 221.52 nM 10.6019/CHEMBL1201861
NPT2404 Cell Line SW982 Homo sapiens IC50 = 166.3 nM 10.6019/CHEMBL1201861
NPT403 Cell Line UACC-257 Homo sapiens IC50 = 5999.92 nM 10.6019/CHEMBL1201861
NPT2065 Cell Line EW-1 Homo sapiens IC50 = 221.38 nM 10.6019/CHEMBL1201861
NPT2066 Cell Line EW-11 Homo sapiens IC50 = 205927.26 nM 10.6019/CHEMBL1201861
NPT2067 Cell Line KARPAS-299 Homo sapiens IC50 = 472.74 nM 10.6019/CHEMBL1201861
NPT2068 Cell Line L-363 Homo sapiens IC50 = 153.11 nM 10.6019/CHEMBL1201861
NPT2069 Cell Line Lu-65 Homo sapiens IC50 = 13895.01 nM 10.6019/CHEMBL1201861
NPT2071 Cell Line MMAC-SF Homo sapiens IC50 = 5203.56 nM 10.6019/CHEMBL1201861
NPT2073 Cell Line NCI-H1304 Homo sapiens IC50 = 163.31 nM 10.6019/CHEMBL1201861
NPT2060 Cell Line NCI-H2171 Homo sapiens IC50 = 6915.72 nM 10.6019/CHEMBL1201861
NPT2075 Cell Line NCI-H2196 Homo sapiens IC50 = 648.41 nM 10.6019/CHEMBL1201861
NPT788 Cell Line SNU1 Homo sapiens IC50 = 400.14 nM 10.6019/CHEMBL1201861
NPT2077 Cell Line SCC-3 Homo sapiens IC50 = 620.41 nM 10.6019/CHEMBL1201861
NPT2078 Cell Line SK-UT-1 Homo sapiens IC50 = 81.38 nM 10.6019/CHEMBL1201861
NPT2079 Cell Line EW-12 Homo sapiens IC50 = 238637.58 nM 10.6019/CHEMBL1201861
NPT2080 Cell Line EW-13 Homo sapiens IC50 = 2666.58 nM 10.6019/CHEMBL1201861
NPT2081 Cell Line HCC1599 Homo sapiens IC50 = 162.28 nM 10.6019/CHEMBL1201861
NPT2082 Cell Line HT-144 Homo sapiens IC50 = 152.59 nM 10.6019/CHEMBL1201861
NPT2083 Cell Line KARPAS-422 Homo sapiens IC50 = 294.33 nM 10.6019/CHEMBL1201861
NPT2084 Cell Line KARPAS-45 Homo sapiens IC50 = 295.7 nM 10.6019/CHEMBL1201861
NPT2085 Cell Line Kasumi 1 IC50 = 66173.3 nM 10.6019/CHEMBL1201861
NPT2086 Cell Line L-428 Homo sapiens IC50 = 21163.54 nM 10.6019/CHEMBL1201861
NPT2087 Cell Line L-540 Homo sapiens IC50 = 345.91 nM 10.6019/CHEMBL1201861
NPT2070 Cell Line LXF-289 cell line IC50 = 179.4 nM 10.6019/CHEMBL1201861
NPT2072 Cell Line MN-60 Homo sapiens IC50 = 487.21 nM 10.6019/CHEMBL1201861
NPT2088 Cell Line MOLT-16 Homo sapiens IC50 = 83.71 nM 10.6019/CHEMBL1201861
NPT2074 Cell Line NCI-H1355 Homo sapiens IC50 = 113.2 nM 10.6019/CHEMBL1201861
NPT2089 Cell Line NCI-H1395 Homo sapiens IC50 = 75870.88 nM 10.6019/CHEMBL1201861
NPT405 Cell Line NCI-H226 Homo sapiens IC50 = 32214.99 nM 10.6019/CHEMBL1201861
NPT2090 Cell Line SNU-16 Homo sapiens IC50 = 1728.12 nM 10.6019/CHEMBL1201861
NPT2091 Cell Line SNU-5 Homo sapiens IC50 = 3842.4 nM 10.6019/CHEMBL1201861
NPT2092 Cell Line NEC8 Homo sapiens IC50 = 3320.59 nM 10.6019/CHEMBL1201861
NPT2093 Cell Line PF-382 Homo sapiens IC50 = 637.67 nM 10.6019/CHEMBL1201861
NPT2094 Cell Line SKM-1 Homo sapiens IC50 = 16973.77 nM 10.6019/CHEMBL1201861
NPT392 Cell Line SNB-75 Homo sapiens IC50 = 115.72 nM 10.6019/CHEMBL1201861
NPT2096 Cell Line VA-ES-BJ Homo sapiens IC50 = 129.3 nM 10.6019/CHEMBL1201861
NPT2097 Cell Line EW-16 Homo sapiens IC50 = 215.98 nM 10.6019/CHEMBL1201861
NPT2098 Cell Line EW-18 Homo sapiens IC50 = 205742.83 nM 10.6019/CHEMBL1201861
NPT2099 Cell Line KE-37 Homo sapiens IC50 = 110.19 nM 10.6019/CHEMBL1201861
NPT2100 Cell Line KG-1 IC50 = 3758.02 nM 10.6019/CHEMBL1201861
NPT1358 Cell Line LAMA-84 Homo sapiens IC50 = 609.69 nM 10.6019/CHEMBL1201861
NPT2101 Cell Line LAN-6 Homo sapiens IC50 = 885.77 nM 10.6019/CHEMBL1201861
NPT2102 Cell Line MC-CAR Homo sapiens IC50 = 1801.28 nM 10.6019/CHEMBL1201861
NPT112 Cell Line MOLT-4 Homo sapiens IC50 = 130.92 nM 10.6019/CHEMBL1201861
NPT2103 Cell Line MONO-MAC-6 Homo sapiens IC50 = 77.23 nM 10.6019/CHEMBL1201861
NPT2104 Cell Line NCI-H1417 Homo sapiens IC50 = 583.77 nM 10.6019/CHEMBL1201861
NPT2105 Cell Line NCI-H1436 Homo sapiens IC50 = 477.24 nM 10.6019/CHEMBL1201861
NPT370 Cell Line NCI-H23 Homo sapiens IC50 = 1173.71 nM 10.6019/CHEMBL1201861
NPT2106 Cell Line NH-12 Homo sapiens IC50 = 133531.18 nM 10.6019/CHEMBL1201861
NPT2107 Cell Line PSN1 Homo sapiens IC50 = 47.29 nM 10.6019/CHEMBL1201861
NPT2109 Cell Line SCH Homo sapiens IC50 = 2132.42 nM 10.6019/CHEMBL1201861
NPT2110 Cell Line SCLC-21H Homo sapiens IC50 = 1357.18 nM 10.6019/CHEMBL1201861
NPT2095 Cell Line TALL-1 Homo sapiens IC50 = 241.79 nM 10.6019/CHEMBL1201861
NPT2112 Cell Line TE-1 Homo sapiens IC50 = 110.54 nM 10.6019/CHEMBL1201861
NPT2113 Cell Line EW-24 Homo sapiens IC50 = 837.09 nM 10.6019/CHEMBL1201861
NPT2115 Cell Line HCC2157 Homo sapiens IC50 = 560.63 nM 10.6019/CHEMBL1201861
NPT2116 Cell Line HCC2218 Homo sapiens IC50 = 266.09 nM 10.6019/CHEMBL1201861
NPT2117 Cell Line HuTu80 Homo sapiens IC50 = 113.71 nM 10.6019/CHEMBL1201861
NPT2118 Cell Line KGN Homo sapiens IC50 = 117.69 nM 10.6019/CHEMBL1201861
NPT2119 Cell Line KINGS-1 Homo sapiens IC50 = 291.91 nM 10.6019/CHEMBL1201861
NPT2120 Cell Line LB1047-RCC Homo sapiens IC50 = 87.19 nM 10.6019/CHEMBL1201861
NPT2121 Cell Line LB2241-RCC Homo sapiens IC50 = 33194.86 nM 10.6019/CHEMBL1201861
NPT2122 Cell Line MC116 Homo sapiens IC50 = 137.46 nM 10.6019/CHEMBL1201861
NPT2123 Cell Line MPP-89 Homo sapiens IC50 = 485.19 nM 10.6019/CHEMBL1201861
NPT2124 Cell Line MRK-nu-1 Homo sapiens IC50 = 103.74 nM 10.6019/CHEMBL1201861
NPT2125 Cell Line NCI-H1522 Homo sapiens IC50 = 464.29 nM 10.6019/CHEMBL1201861
NPT2126 Cell Line NKM-1 Homo sapiens IC50 = 6195.98 nM 10.6019/CHEMBL1201861
NPT2127 Cell Line NMC-G1 Homo sapiens IC50 = 880.43 nM 10.6019/CHEMBL1201861
NPT2108 Cell Line QIMR-WIL Homo sapiens IC50 = 256.47 nM 10.6019/CHEMBL1201861
NPT2128 Cell Line RCC10RGB Homo sapiens IC50 = 16089.98 nM 10.6019/CHEMBL1201861
NPT2111 Cell Line SF-126 Homo sapiens IC50 = 310.74 nM 10.6019/CHEMBL1201861
NPT395 Cell Line SF-268 Homo sapiens IC50 = 2856.94 nM 10.6019/CHEMBL1201861
NPT2129 Cell Line SNU-C1 Homo sapiens IC50 = 2631.62 nM 10.6019/CHEMBL1201861
NPT2130 Cell Line TE-10 Homo sapiens IC50 = 89.4 nM 10.6019/CHEMBL1201861
NPT2456 Cell Line TE-11 Homo sapiens IC50 = 130.16 nM 10.6019/CHEMBL1201861
NPT2131 Cell Line WSU-NHL Homo sapiens IC50 = 188382.41 nM 10.6019/CHEMBL1201861
NPT2114 Cell Line EW-3 Homo sapiens IC50 = 1113.46 nM 10.6019/CHEMBL1201861
NPT2132 Cell Line EOL1 Homo sapiens IC50 = 164.89 nM 10.6019/CHEMBL1201861
NPT2448 Cell Line KLE Homo sapiens IC50 = 226.05 nM 10.6019/CHEMBL1201861
NPT2134 Cell Line LB2518-MEL Homo sapiens IC50 = 397.21 nM 10.6019/CHEMBL1201861
NPT2135 Cell Line LB373-MEL-D Homo sapiens IC50 = 531.12 nM 10.6019/CHEMBL1201861
NPT2136 Cell Line MDA-MB-134-VI Homo sapiens IC50 = 489.17 nM 10.6019/CHEMBL1201861
NPT2137 Cell Line MS-1 Homo sapiens IC50 = 3549.84 nM 10.6019/CHEMBL1201861
NPT2138 Cell Line MSTO-211H Homo sapiens IC50 = 105678.98 nM 10.6019/CHEMBL1201861
NPT2139 Cell Line NCI-H1581 Homo sapiens IC50 = 605.82 nM 10.6019/CHEMBL1201861
NPT2140 Cell Line NOMO-1 Homo sapiens IC50 = 560.7 nM 10.6019/CHEMBL1201861
NPT2141 Cell Line NOS-1 Homo sapiens IC50 = 93.76 nM 10.6019/CHEMBL1201861
NPT2142 Cell Line REH Homo sapiens IC50 = 12898.45 nM 10.6019/CHEMBL1201861
NPT374 Cell Line SF-539 Homo sapiens IC50 = 3793.07 nM 10.6019/CHEMBL1201861
NPT2455 Cell Line SNU-C2B Homo sapiens IC50 = 290.27 nM 10.6019/CHEMBL1201861
NPT385 Cell Line SR Homo sapiens IC50 = 183.83 nM 10.6019/CHEMBL1201861
NPT2144 Cell Line TE-12 Homo sapiens IC50 = 193.83 nM 10.6019/CHEMBL1201861
NPT2146 Cell Line YT Homo sapiens IC50 = 274977.97 nM 10.6019/CHEMBL1201861
NPT2460 Cell Line HCE-4 Homo sapiens IC50 = 104.44 nM 10.6019/CHEMBL1201861
NPT2133 Cell Line KM-H2 Homo sapiens IC50 = 1779.71 nM 10.6019/CHEMBL1201861
NPT386 Cell Line KM12 Homo sapiens IC50 = 140.89 nM 10.6019/CHEMBL1201861
NPT2147 Cell Line LB647-SCLC Homo sapiens IC50 = 224.03 nM 10.6019/CHEMBL1201861
NPT2148 Cell Line LB771-HNC Homo sapiens IC50 = 222.39 nM 10.6019/CHEMBL1201861
NPT1649 Cell Line MV4-11 Homo sapiens IC50 = 57.74 nM 10.6019/CHEMBL1201861
NPT2149 Cell Line MZ1-PC Homo sapiens IC50 = 79.54 nM 10.6019/CHEMBL1201861
NPT2150 Cell Line NCI-H1648 Homo sapiens IC50 = 183.32 nM 10.6019/CHEMBL1201861
NPT388 Cell Line NCI-H322M Homo sapiens IC50 = 7232.24 nM 10.6019/CHEMBL1201861
NPT2151 Cell Line NCI-H345 Homo sapiens IC50 = 750.32 nM 10.6019/CHEMBL1201861
NPT2152 Cell Line NTERA-2-cl-D1 Homo sapiens IC50 = 27.59 nM 10.6019/CHEMBL1201861
NPT2153 Cell Line RH-1 Homo sapiens IC50 = 106593.34 nM 10.6019/CHEMBL1201861
NPT2154 Cell Line SH-4 Homo sapiens IC50 = 184.99 nM 10.6019/CHEMBL1201861
NPT2155 Cell Line SHP77 Homo sapiens IC50 = 10563.05 nM 10.6019/CHEMBL1201861
NPT2143 Cell Line ST486 Homo sapiens IC50 = 203.93 nM 10.6019/CHEMBL1201861
NPT2156 Cell Line SU-DHL-1 Homo sapiens IC50 = 796.93 nM 10.6019/CHEMBL1201861
NPT2157 Cell Line SUP-T1 Homo sapiens IC50 = 276180.32 nM 10.6019/CHEMBL1201861
NPT2145 Cell Line TE-15 Homo sapiens IC50 = 59.09 nM 10.6019/CHEMBL1201861
NPT2158 Cell Line TE-441-T Homo sapiens IC50 = 797.81 nM 10.6019/CHEMBL1201861
NPT2159 Cell Line TE-5 Homo sapiens IC50 = 168.89 nM 10.6019/CHEMBL1201861
NPT2160 Cell Line no-10 Homo sapiens IC50 = 129.02 nM 10.6019/CHEMBL1201861
NPT2161 Cell Line no-11 Homo sapiens IC50 = 129.9 nM 10.6019/CHEMBL1201861
NPT2162 Cell Line HCE-T Homo sapiens IC50 = 450.8 nM 10.6019/CHEMBL1201861
NPT2485 Cell Line IA-LM Homo sapiens IC50 = 200 nM 10.6019/CHEMBL1201861
NPT2163 Cell Line KMOE-2 Homo sapiens IC50 = 1489.95 nM 10.6019/CHEMBL1201861
NPT2164 Cell Line KMS-12-PE Homo sapiens IC50 = 47462.6 nM 10.6019/CHEMBL1201861
NPT2165 Cell Line KNS-42 Homo sapiens IC50 = 248.2 nM 10.6019/CHEMBL1201861
NPT2166 Cell Line LB831-BLC Homo sapiens IC50 = 194.08 nM 10.6019/CHEMBL1201861
NPT2167 Cell Line LB996-RCC Homo sapiens IC50 = 122.19 nM 10.6019/CHEMBL1201861
NPT2168 Cell Line MZ2-MEL Homo sapiens IC50 = 2100.26 nM 10.6019/CHEMBL1201861
NPT1820 Cell Line NCI-H1650 Homo sapiens IC50 = 1865.21 nM 10.6019/CHEMBL1201861
NPT937 Cell Line NCI-H446 Homo sapiens IC50 = 394.93 nM 10.6019/CHEMBL1201861
NPT2170 Cell Line RKO Homo sapiens IC50 = 136.17 nM 10.6019/CHEMBL1201861
NPT2171 Cell Line SIG-M5 Homo sapiens IC50 = 130.47 nM 10.6019/CHEMBL1201861
NPT2172 Cell Line SIMA Homo sapiens IC50 = 246153.42 nM 10.6019/CHEMBL1201861
NPT2173 Cell Line TE-6 Homo sapiens IC50 = 860.22 nM 10.6019/CHEMBL1201861
NPT2174 Cell Line TE-8 Homo sapiens IC50 = 137.48 nM 10.6019/CHEMBL1201861
NPT2175 Cell Line GAK Homo sapiens IC50 = 16810.39 nM 10.6019/CHEMBL1201861
NPT2176 Cell Line HD-MY-Z Homo sapiens IC50 = 1774.7 nM 10.6019/CHEMBL1201861
NPT2178 Cell Line KNS-81-FD Homo sapiens IC50 = 1799.56 nM 10.6019/CHEMBL1201861
NPT2179 Cell Line LC-1F Homo sapiens IC50 = 181.05 nM 10.6019/CHEMBL1201861
NPT2180 Cell Line LC-2-ad Homo sapiens IC50 = 22.15 nM 10.6019/CHEMBL1201861
NPT2181 Cell Line MEG-01 Homo sapiens IC50 = 813.84 nM 10.6019/CHEMBL1201861
NPT2169 Cell Line MZ7-mel Homo sapiens IC50 = 564.34 nM 10.6019/CHEMBL1201861
NPT2183 Cell Line NCI-H1694 Homo sapiens IC50 = 508.67 nM 10.6019/CHEMBL1201861
NPT2184 Cell Line NCI-H510A Homo sapiens IC50 = 229.2 nM 10.6019/CHEMBL1201861
NPT2185 Cell Line OCI-AML2 Homo sapiens IC50 = 210.37 nM 10.6019/CHEMBL1201861
NPT2186 Cell Line RL Homo sapiens IC50 = 173261.67 nM 10.6019/CHEMBL1201861
NPT2187 Cell Line RL95-2 Homo sapiens IC50 = 22.81 nM 10.6019/CHEMBL1201861
NPT2188 Cell Line SJSA-1 Homo sapiens IC50 = 376.5 nM 10.6019/CHEMBL1201861
NPT2189 Cell Line TE-9 Homo sapiens IC50 = 388.97 nM 10.6019/CHEMBL1201861
NPT2190 Cell Line GB-1 Homo sapiens IC50 = 199.12 nM 10.6019/CHEMBL1201861
NPT2191 Cell Line GCIY Homo sapiens IC50 = 261.31 nM 10.6019/CHEMBL1201861
NPT2177 Cell Line HDLM-2 Homo sapiens IC50 = 3166.35 nM 10.6019/CHEMBL1201861
NPT2192 Cell Line HEL Homo sapiens IC50 = 422.46 nM 10.6019/CHEMBL1201861
NPT2193 Cell Line IM-9 Homo sapiens IC50 = 35702.51 nM 10.6019/CHEMBL1201861
NPT2194 Cell Line IMR-5 Homo sapiens IC50 = 599.66 nM 10.6019/CHEMBL1201861
NPT2195 Cell Line LC4-1 Homo sapiens IC50 = 216.65 nM 10.6019/CHEMBL1201861
NPT2182 Cell Line Mo Homo sapiens IC50 = 28646.03 nM 10.6019/CHEMBL1201861
NPT623 Cell Line NALM-6 Homo sapiens IC50 = 127.98 nM 10.6019/CHEMBL1201861
NPT2196 Cell Line NB1 Homo sapiens IC50 = 117.48 nM 10.6019/CHEMBL1201861
NPT2198 Cell Line NCI-H524 Homo sapiens IC50 = 859.54 nM 10.6019/CHEMBL1201861
NPT2199 Cell Line OCUB-M Homo sapiens IC50 = 25.73 nM 10.6019/CHEMBL1201861
NPT2200 Cell Line RPMI-6666 Homo sapiens IC50 = 151.72 nM 10.6019/CHEMBL1201861
NPT2201 Cell Line SK-LMS-1 Homo sapiens IC50 = 276.37 nM 10.6019/CHEMBL1201861
NPT2202 Cell Line TGBC1TKB Homo sapiens IC50 = 120.43 nM 10.6019/CHEMBL1201861
NPT2339 Cell Line TGBC24TKB Homo sapiens IC50 = 810.31 nM 10.6019/CHEMBL1201861
NPT2203 Cell Line GDM-1 Homo sapiens IC50 = 9550.22 nM 10.6019/CHEMBL1201861
NPT2204 Cell Line HH Homo sapiens IC50 = 223.23 nM 10.6019/CHEMBL1201861
NPT2205 Cell Line IST-MEL1 Homo sapiens IC50 = 446.62 nM 10.6019/CHEMBL1201861
NPT2206 Cell Line IST-MES1 Homo sapiens IC50 = 1780.12 nM 10.6019/CHEMBL1201861
NPT5022 Cell Line KP-N-RT-BM-1 Homo sapiens IC50 = 910.79 nM 10.6019/CHEMBL1201861
NPT2208 Cell Line KP-N-YS Homo sapiens IC50 = 4863.3 nM 10.6019/CHEMBL1201861
NPT2210 Cell Line NB10 Homo sapiens IC50 = 6379.27 nM 10.6019/CHEMBL1201861
NPT2197 Cell Line NCI-H1770 Homo sapiens IC50 = 212460.48 nM 10.6019/CHEMBL1201861
NPT2 Others Unspecified Potency 1258.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 1299.5 nM PubChem BioAssay data set
NPT154 Individual Protein Mothers against decapentaplegic homolog 3 Homo sapiens Potency 1636 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 7307.8 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 891.3 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 316.2 nM PubChem BioAssay data set

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC180504 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.8214 Intermediate Similarity NPC314954
0.8157 Intermediate Similarity NPC94157
0.8111 Intermediate Similarity NPC208284
0.8106 Intermediate Similarity NPC469554
0.8 Intermediate Similarity NPC470549
0.7982 Intermediate Similarity NPC132642
0.7981 Intermediate Similarity NPC19872
0.7964 Intermediate Similarity NPC170114
0.7948 Intermediate Similarity NPC101543
0.7917 Intermediate Similarity NPC285558
0.787 Intermediate Similarity NPC476138
0.787 Intermediate Similarity NPC245816
0.787 Intermediate Similarity NPC475774
0.7826 Intermediate Similarity NPC475253
0.781 Intermediate Similarity NPC76748
0.7808 Intermediate Similarity NPC476465
0.7773 Intermediate Similarity NPC92111
0.7773 Intermediate Similarity NPC473181
0.7762 Intermediate Similarity NPC296527
0.7748 Intermediate Similarity NPC26679
0.7738 Intermediate Similarity NPC167860
0.7738 Intermediate Similarity NPC123976
0.7738 Intermediate Similarity NPC199667
0.7731 Intermediate Similarity NPC176538
0.7713 Intermediate Similarity NPC476287
0.77 Intermediate Similarity NPC307963
0.7696 Intermediate Similarity NPC473185
0.7678 Intermediate Similarity NPC242928
0.7668 Intermediate Similarity NPC473180
0.7615 Intermediate Similarity NPC232727
0.7613 Intermediate Similarity NPC185782
0.7574 Intermediate Similarity NPC39370
0.7569 Intermediate Similarity NPC329793
0.7569 Intermediate Similarity NPC329747
0.7564 Intermediate Similarity NPC473186
0.7546 Intermediate Similarity NPC251090
0.7544 Intermediate Similarity NPC193267
0.7544 Intermediate Similarity NPC473179
0.7544 Intermediate Similarity NPC213530
0.7523 Intermediate Similarity NPC128823
0.7512 Intermediate Similarity NPC267928
0.7511 Intermediate Similarity NPC477533
0.749 Intermediate Similarity NPC26543
0.7479 Intermediate Similarity NPC471891
0.7477 Intermediate Similarity NPC72211
0.7465 Intermediate Similarity NPC70259
0.7465 Intermediate Similarity NPC13880
0.7454 Intermediate Similarity NPC84853
0.7437 Intermediate Similarity NPC473183
0.7432 Intermediate Similarity NPC470930
0.7432 Intermediate Similarity NPC475070
0.7426 Intermediate Similarity NPC24802
0.7422 Intermediate Similarity NPC5145
0.7419 Intermediate Similarity NPC205934
0.7419 Intermediate Similarity NPC43787
0.7415 Intermediate Similarity NPC196718
0.7412 Intermediate Similarity NPC470799
0.7412 Intermediate Similarity NPC8022
0.7411 Intermediate Similarity NPC477111
0.7411 Intermediate Similarity NPC314957
0.7409 Intermediate Similarity NPC121772
0.7406 Intermediate Similarity NPC284678
0.7401 Intermediate Similarity NPC266931
0.7401 Intermediate Similarity NPC469592
0.7401 Intermediate Similarity NPC471080
0.7399 Intermediate Similarity NPC477113
0.7393 Intermediate Similarity NPC474798
0.7387 Intermediate Similarity NPC162484
0.738 Intermediate Similarity NPC304926
0.738 Intermediate Similarity NPC476041
0.7376 Intermediate Similarity NPC476044
0.7375 Intermediate Similarity NPC477861
0.7364 Intermediate Similarity NPC187558
0.7353 Intermediate Similarity NPC473184
0.7345 Intermediate Similarity NPC11464
0.7345 Intermediate Similarity NPC471304
0.7342 Intermediate Similarity NPC102593
0.7339 Intermediate Similarity NPC53534
0.7336 Intermediate Similarity NPC288349
0.7336 Intermediate Similarity NPC477110
0.7333 Intermediate Similarity NPC101350
0.7333 Intermediate Similarity NPC475910
0.7328 Intermediate Similarity NPC310118
0.7328 Intermediate Similarity NPC477532
0.7316 Intermediate Similarity NPC292958
0.7311 Intermediate Similarity NPC141053
0.7302 Intermediate Similarity NPC152620
0.7297 Intermediate Similarity NPC267423
0.7294 Intermediate Similarity NPC475190
0.7292 Intermediate Similarity NPC235685
0.729 Intermediate Similarity NPC473189
0.729 Intermediate Similarity NPC15102
0.7285 Intermediate Similarity NPC287437
0.7277 Intermediate Similarity NPC470500
0.7277 Intermediate Similarity NPC176127
0.7273 Intermediate Similarity NPC469594
0.7265 Intermediate Similarity NPC130570
0.7265 Intermediate Similarity NPC475085
0.7265 Intermediate Similarity NPC291535
0.7265 Intermediate Similarity NPC475112
0.7261 Intermediate Similarity NPC11408
0.7257 Intermediate Similarity NPC287208
0.7249 Intermediate Similarity NPC478074
0.7248 Intermediate Similarity NPC99666
0.7248 Intermediate Similarity NPC324149
0.7246 Intermediate Similarity NPC110151
0.7244 Intermediate Similarity NPC476106
0.7232 Intermediate Similarity NPC223427
0.7227 Intermediate Similarity NPC476451
0.7227 Intermediate Similarity NPC194967
0.722 Intermediate Similarity NPC15801
0.7207 Intermediate Similarity NPC476167
0.7202 Intermediate Similarity NPC217554
0.7195 Intermediate Similarity NPC77555
0.7195 Intermediate Similarity NPC243834
0.7195 Intermediate Similarity NPC70956
0.7188 Intermediate Similarity NPC193761
0.7186 Intermediate Similarity NPC472027
0.7184 Intermediate Similarity NPC284141
0.7182 Intermediate Similarity NPC131017
0.7178 Intermediate Similarity NPC295228
0.7176 Intermediate Similarity NPC171171
0.7175 Intermediate Similarity NPC315957
0.7174 Intermediate Similarity NPC162530
0.7174 Intermediate Similarity NPC477610
0.7173 Intermediate Similarity NPC6215
0.7171 Intermediate Similarity NPC258048
0.717 Intermediate Similarity NPC59269
0.7167 Intermediate Similarity NPC473182
0.7163 Intermediate Similarity NPC84478
0.7163 Intermediate Similarity NPC204717
0.7162 Intermediate Similarity NPC192315
0.7149 Intermediate Similarity NPC216612
0.7149 Intermediate Similarity NPC201697
0.7149 Intermediate Similarity NPC209769
0.7143 Intermediate Similarity NPC252251
0.7131 Intermediate Similarity NPC103687
0.7131 Intermediate Similarity NPC153467
0.7131 Intermediate Similarity NPC132631
0.7131 Intermediate Similarity NPC81175
0.713 Intermediate Similarity NPC314002
0.7125 Intermediate Similarity NPC49547
0.7124 Intermediate Similarity NPC96321
0.7116 Intermediate Similarity NPC220765
0.7112 Intermediate Similarity NPC36405
0.7106 Intermediate Similarity NPC60621
0.7102 Intermediate Similarity NPC478081
0.71 Intermediate Similarity NPC473757
0.7093 Intermediate Similarity NPC470164
0.7093 Intermediate Similarity NPC323345
0.7087 Intermediate Similarity NPC187501
0.7085 Intermediate Similarity NPC475666
0.7083 Intermediate Similarity NPC260434
0.7083 Intermediate Similarity NPC477531
0.7074 Intermediate Similarity NPC469589
0.7061 Intermediate Similarity NPC477066
0.7059 Intermediate Similarity NPC227908
0.7056 Intermediate Similarity NPC48353
0.7056 Intermediate Similarity NPC316981
0.7054 Intermediate Similarity NPC18487
0.7051 Intermediate Similarity NPC473041
0.7048 Intermediate Similarity NPC118832
0.7048 Intermediate Similarity NPC47059
0.7048 Intermediate Similarity NPC165349
0.7048 Intermediate Similarity NPC329708
0.7048 Intermediate Similarity NPC264166
0.7048 Intermediate Similarity NPC274291
0.7045 Intermediate Similarity NPC81939
0.7042 Intermediate Similarity NPC209174
0.7042 Intermediate Similarity NPC224764
0.7033 Intermediate Similarity NPC477067
0.7033 Intermediate Similarity NPC478082
0.7031 Intermediate Similarity NPC82548
0.7028 Intermediate Similarity NPC91868
0.7028 Intermediate Similarity NPC63971
0.7026 Intermediate Similarity NPC39500
0.7022 Intermediate Similarity NPC234197
0.7014 Intermediate Similarity NPC195268
0.7014 Intermediate Similarity NPC133140
0.7012 Intermediate Similarity NPC474688
0.7009 Intermediate Similarity NPC305984
0.7 Intermediate Similarity NPC95783
0.7 Intermediate Similarity NPC476116
0.6992 Remote Similarity NPC225279
0.6992 Remote Similarity NPC86078
0.6987 Remote Similarity NPC193777
0.6987 Remote Similarity NPC202503
0.6987 Remote Similarity NPC470018
0.6986 Remote Similarity NPC46580
0.6986 Remote Similarity NPC317030
0.6979 Remote Similarity NPC477609
0.6977 Remote Similarity NPC42979
0.6976 Remote Similarity NPC78609
0.6976 Remote Similarity NPC208522
0.6975 Remote Similarity NPC122436
0.6971 Remote Similarity NPC326363
0.697 Remote Similarity NPC290689
0.6966 Remote Similarity NPC251936
0.6964 Remote Similarity NPC473540
0.6964 Remote Similarity NPC473312

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC180504 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.8605 High Similarity NPD3402 Phase 1
0.8592 High Similarity NPD6140 Clinical (unspecified phase)
0.8304 Intermediate Similarity NPD5044 Phase 2
0.8282 Intermediate Similarity NPD4343 Phase 1
0.8282 Intermediate Similarity NPD4344 Clinical (unspecified phase)
0.822 Intermediate Similarity NPD6961 Discontinued
0.7895 Intermediate Similarity NPD5559 Phase 2
0.7883 Intermediate Similarity NPD5612 Discontinued
0.785 Intermediate Similarity NPD3825 Phase 3
0.7808 Intermediate Similarity NPD2187 Approved
0.7808 Intermediate Similarity NPD2189 Approved
0.7783 Intermediate Similarity NPD1304 Clinical (unspecified phase)
0.7723 Intermediate Similarity NPD6147 Clinical (unspecified phase)
0.7718 Intermediate Similarity NPD7659 Discontinued
0.7717 Intermediate Similarity NPD8403 Phase 1
0.7703 Intermediate Similarity NPD3939 Suspended
0.77 Intermediate Similarity NPD1038 Approved
0.7692 Intermediate Similarity NPD3343 Phase 3
0.7685 Intermediate Similarity NPD4118 Clinical (unspecified phase)
0.7682 Intermediate Similarity NPD7558 Phase 2
0.7653 Intermediate Similarity NPD3404 Approved
0.7649 Intermediate Similarity NPD5018 Phase 3
0.7626 Intermediate Similarity NPD4886 Phase 2
0.7623 Intermediate Similarity NPD5066 Phase 2
0.7623 Intermediate Similarity NPD5067 Phase 2
0.7619 Intermediate Similarity NPD6610 Clinical (unspecified phase)
0.7611 Intermediate Similarity NPD7823 Clinical (unspecified phase)
0.7605 Intermediate Similarity NPD7392 Phase 2
0.7602 Intermediate Similarity NPD1392 Approved
0.7589 Intermediate Similarity NPD3330 Phase 1
0.7588 Intermediate Similarity NPD7678 Clinical (unspecified phase)
0.7573 Intermediate Similarity NPD4440 Clinical (unspecified phase)
0.7557 Intermediate Similarity NPD3003 Approved
0.7556 Intermediate Similarity NPD5944 Phase 1
0.7556 Intermediate Similarity NPD5945 Phase 1
0.7553 Intermediate Similarity NPD6750 Phase 2
0.7546 Intermediate Similarity NPD3477 Phase 2
0.7546 Intermediate Similarity NPD3478 Clinical (unspecified phase)
0.7521 Intermediate Similarity NPD6131 Phase 1
0.7511 Intermediate Similarity NPD4421 Approved
0.75 Intermediate Similarity NPD5256 Discontinued
0.75 Intermediate Similarity NPD3324 Clinical (unspecified phase)
0.75 Intermediate Similarity NPD7051 Phase 3
0.75 Intermediate Similarity NPD7050 Clinical (unspecified phase)
0.7469 Intermediate Similarity NPD5483 Clinical (unspecified phase)
0.7455 Intermediate Similarity NPD2125 Clinical (unspecified phase)
0.7448 Intermediate Similarity NPD4858 Phase 2
0.7445 Intermediate Similarity NPD5902 Approved
0.7445 Intermediate Similarity NPD5903 Approved
0.7431 Intermediate Similarity NPD7948 Phase 1
0.7427 Intermediate Similarity NPD565 Phase 2
0.7404 Intermediate Similarity NPD6968 Phase 2
0.7404 Intermediate Similarity NPD6969 Phase 2
0.7399 Intermediate Similarity NPD3842 Clinical (unspecified phase)
0.7389 Intermediate Similarity NPD3570 Phase 2
0.7389 Intermediate Similarity NPD6220 Phase 3
0.7383 Intermediate Similarity NPD1033 Clinical (unspecified phase)
0.7383 Intermediate Similarity NPD1034 Phase 3
0.7381 Intermediate Similarity NPD4442 Phase 2
0.7375 Intermediate Similarity NPD2921 Clinical (unspecified phase)
0.7366 Intermediate Similarity NPD7222 Phase 2
0.7362 Intermediate Similarity NPD6759 Phase 2
0.7357 Intermediate Similarity NPD4927 Discontinued
0.7355 Intermediate Similarity NPD7592 Phase 2
0.7348 Intermediate Similarity NPD4429 Discontinued
0.7347 Intermediate Similarity NPD5482 Discontinued
0.7339 Intermediate Similarity NPD6306 Phase 2
0.7339 Intermediate Similarity NPD6251 Discontinued
0.7336 Intermediate Similarity NPD4919 Phase 3
0.7336 Intermediate Similarity NPD4921 Phase 3
0.7336 Intermediate Similarity NPD4920 Clinical (unspecified phase)
0.7333 Intermediate Similarity NPD5528 Clinical (unspecified phase)
0.7333 Intermediate Similarity NPD5529 Phase 1
0.7331 Intermediate Similarity NPD5022 Discontinued
0.7328 Intermediate Similarity NPD4881 Clinical (unspecified phase)
0.7327 Intermediate Similarity NPD6569 Phase 2
0.7322 Intermediate Similarity NPD3006 Discontinued
0.7321 Intermediate Similarity NPD6150 Discontinued
0.7316 Intermediate Similarity NPD7194 Discontinued
0.7316 Intermediate Similarity NPD3875 Discontinued
0.7294 Intermediate Similarity NPD5575 Clinical (unspecified phase)
0.7285 Intermediate Similarity NPD1768 Approved
0.7284 Intermediate Similarity NPD6242 Discontinued
0.7257 Intermediate Similarity NPD5842 Clinical (unspecified phase)
0.7251 Intermediate Similarity NPD3504 Approved
0.7251 Intermediate Similarity NPD3503 Approved
0.725 Intermediate Similarity NPD4454 Phase 2
0.7236 Intermediate Similarity NPD5644 Phase 1
0.7222 Intermediate Similarity NPD6160 Clinical (unspecified phase)
0.7215 Intermediate Similarity NPD1624 Phase 2
0.7212 Intermediate Similarity NPD7452 Approved
0.7212 Intermediate Similarity NPD7453 Approved
0.721 Intermediate Similarity NPD6634 Clinical (unspecified phase)
0.721 Intermediate Similarity NPD6633 Phase 2
0.7207 Intermediate Similarity NPD5999 Phase 2
0.7207 Intermediate Similarity NPD4548 Discontinued
0.7206 Intermediate Similarity NPD6243 Phase 3
0.7206 Intermediate Similarity NPD6244 Phase 3
0.7202 Intermediate Similarity NPD5912 Clinical (unspecified phase)
0.7202 Intermediate Similarity NPD5913 Phase 3
0.72 Intermediate Similarity NPD4795 Phase 2
0.7198 Intermediate Similarity NPD6985 Discontinued
0.7191 Intermediate Similarity NPD5045 Phase 2
0.7188 Intermediate Similarity NPD6208 Discontinued
0.7183 Intermediate Similarity NPD6595 Phase 3
0.7183 Intermediate Similarity NPD6531 Approved
0.7183 Intermediate Similarity NPD6530 Approved
0.7181 Intermediate Similarity NPD5658 Approved
0.7175 Intermediate Similarity NPD1739 Approved
0.7175 Intermediate Similarity NPD1740 Approved
0.717 Intermediate Similarity NPD4072 Approved
0.717 Intermediate Similarity NPD4071 Approved
0.7168 Intermediate Similarity NPD4862 Clinical (unspecified phase)
0.7167 Intermediate Similarity NPD6494 Phase 2
0.7167 Intermediate Similarity NPD3514 Clinical (unspecified phase)
0.7165 Intermediate Similarity NPD5949 Phase 3
0.7156 Intermediate Similarity NPD5065 Approved
0.7143 Intermediate Similarity NPD7067 Approved
0.7143 Intermediate Similarity NPD7068 Approved
0.7131 Intermediate Similarity NPD5911 Clinical (unspecified phase)
0.7124 Intermediate Similarity NPD5948 Phase 2
0.7101 Intermediate Similarity NPD6553 Clinical (unspecified phase)
0.7092 Intermediate Similarity NPD8442 Discontinued
0.7089 Intermediate Similarity NPD6203 Clinical (unspecified phase)
0.7087 Intermediate Similarity NPD7470 Discontinued
0.7087 Intermediate Similarity NPD4502 Phase 2
0.7083 Intermediate Similarity NPD5083 Clinical (unspecified phase)
0.7082 Intermediate Similarity NPD3440 Clinical (unspecified phase)
0.7076 Intermediate Similarity NPD6824 Clinical (unspecified phase)
0.7073 Intermediate Similarity NPD5802 Phase 2
0.7061 Intermediate Similarity NPD4865 Approved
0.7059 Intermediate Similarity NPD7176 Clinical (unspecified phase)
0.7059 Intermediate Similarity NPD7603 Discontinued
0.7053 Intermediate Similarity NPD1418 Phase 2
0.7052 Intermediate Similarity NPD4353 Phase 2
0.7051 Intermediate Similarity NPD5632 Approved
0.7051 Intermediate Similarity NPD4889 Approved
0.7048 Intermediate Similarity NPD4033 Approved
0.7048 Intermediate Similarity NPD4035 Approved
0.7048 Intermediate Similarity NPD4122 Approved
0.7048 Intermediate Similarity NPD4039 Approved
0.7048 Intermediate Similarity NPD3397 Phase 2
0.7048 Intermediate Similarity NPD4034 Approved
0.7048 Intermediate Similarity NPD4038 Approved
0.7048 Intermediate Similarity NPD32 Approved
0.7048 Intermediate Similarity NPD31 Approved
0.7048 Intermediate Similarity NPD4036 Approved
0.7048 Intermediate Similarity NPD4037 Approved
0.7042 Intermediate Similarity NPD5479 Discontinued
0.7042 Intermediate Similarity NPD8512 Phase 3
0.7035 Intermediate Similarity NPD5669 Clinical (unspecified phase)
0.7027 Intermediate Similarity NPD1951 Clinical (unspecified phase)
0.7027 Intermediate Similarity NPD6491 Clinical (unspecified phase)
0.7027 Intermediate Similarity NPD6861 Clinical (unspecified phase)
0.7026 Intermediate Similarity NPD1322 Clinical (unspecified phase)
0.7018 Intermediate Similarity NPD2444 Phase 2
0.7017 Intermediate Similarity NPD3938 Phase 1
0.7017 Intermediate Similarity NPD4890 Phase 2
0.7016 Intermediate Similarity NPD8100 Phase 3
0.7014 Intermediate Similarity NPD3922 Approved
0.7014 Intermediate Similarity NPD3921 Approved
0.7014 Intermediate Similarity NPD3923 Approved
0.7014 Intermediate Similarity NPD3924 Approved
0.7013 Intermediate Similarity NPD4131 Phase 3
0.7009 Intermediate Similarity NPD3084 Phase 3
0.7009 Intermediate Similarity NPD1032 Phase 2
0.7004 Intermediate Similarity NPD5450 Discontinued
0.7004 Intermediate Similarity NPD6736 Discontinued
0.7 Intermediate Similarity NPD6956 Phase 1
0.6996 Remote Similarity NPD4295 Clinical (unspecified phase)
0.6996 Remote Similarity NPD6528 Phase 1
0.6996 Remote Similarity NPD6760 Discontinued
0.6983 Remote Similarity NPD5097 Phase 2
0.6981 Remote Similarity NPD1078 Clinical (unspecified phase)
0.6979 Remote Similarity NPD8405 Clinical (unspecified phase)
0.6972 Remote Similarity NPD7424 Clinical (unspecified phase)
0.6972 Remote Similarity NPD6503 Clinical (unspecified phase)
0.6971 Remote Similarity NPD3302 Clinical (unspecified phase)
0.6966 Remote Similarity NPD6772 Clinical (unspecified phase)
0.6964 Remote Similarity NPD6473 Phase 1
0.6957 Remote Similarity NPD2510 Approved
0.6957 Remote Similarity NPD2509 Approved
0.6951 Remote Similarity NPD6590 Discontinued
0.6951 Remote Similarity NPD4418 Discontinued
0.6938 Remote Similarity NPD8284 Discontinued
0.6937 Remote Similarity NPD4372 Phase 1
0.6932 Remote Similarity NPD8101 Phase 3
0.693 Remote Similarity NPD2144 Approved
0.6923 Remote Similarity NPD3255 Phase 1
0.6923 Remote Similarity NPD3254 Phase 1
0.6923 Remote Similarity NPD3342 Phase 2
0.692 Remote Similarity NPD8358 Approved
0.692 Remote Similarity NPD6205 Discontinued
0.6917 Remote Similarity NPD3844 Clinical (unspecified phase)
0.6917 Remote Similarity NPD2311 Clinical (unspecified phase)
0.6916 Remote Similarity NPD4511 Phase 1
0.6912 Remote Similarity NPD4204 Approved
0.6912 Remote Similarity NPD4203 Approved
0.6912 Remote Similarity NPD7414 Clinical (unspecified phase)
0.6911 Remote Similarity NPD7673 Phase 3

Structure

External Identifiers

PubChem CID   10172943
ChEMBL   CHEMBL379300
ZINC  

Physicochemical Properties

Molecular Weight:  397.19
ALogP:  -1.2817
MLogP:  3.44
XLogP:  4.207
# Rotatable Bonds:  8
Polar Surface Area:  92.61
# H-Bond Aceptor:  5
# H-Bond Donor:  3
# Rings:  5
# Heavy Atoms:  30

Download Data

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General Info & Identifiers & Properties  
Structure MOL file  
Source Organisms  
Biological Activities  
Similar NPs/Drugs