NPASS Natural Product

Natural Product: NPC139867

Natural Product ID:	NPC139867
Common Name:	Mitomycin
IUPAC Name:
Synonyms:	Mitomycin; Mitomycin C; Mitosol; Mitozytrex; Mutamycin; Mytozytrex; NSC-26980
Molecular Formula:	C15H18N4O5
Standard InCHIKey:	NWIBSHFKIJFRCO-WUDYKRTCSA-N
Standard InCHI:	InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
Canonical SMILES:	CO[C@@]12[C@H]3N[C@H]3CN2C2=C([C@H]1COC(=N)O)C(=O)C(=C(C2=O)C)N
First Find Year:
Max Developmental Stage:
Synthetic Gene Cluster:	;

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Reference
NPO22810	Streptomyces	Species	Streptomycetaceae	Bacteria	StreptomeDB*
NPO9597	Streptomyces verticillatus	Species	Streptomycetaceae	Bacteria	StreptomeDB*
NPO13952	Streptomyces lavendulae	Species	Streptomycetaceae	Bacteria	StreptomeDB*
NPO13952.16	Streptomyces lavendulae nrrl 2564	Subspecies	Streptomycetaceae	Bacteria	StreptomeDB*
NPO7758	Streptomyces caespitosus	Species	Streptomycetaceae	Bacteria	StreptomeDB*

Biological Activity

Activity Type	# Activity
AC50	6
EC50	10
ED50	33
GI50	80
IC50	873
Ki	1
LD50	2
MIC	8
Others	187
Potency	50

Activity Type	# Activity
Cell Line	1040
Individual Protein	9
Organism	61
Others	133
Uncleic Acid	7

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT137	Cell Line	L1210	Mus musculus	IC50	=	90	nM	1906107
NPT137	Cell Line	L1210	Mus musculus	IC50	=	1500	nM	1906107
NPT2	Others	Unspecified		Ratio	=	16.7		1906107
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	58	%	11311054
NPT146	Cell Line	SK-OV-3	Homo sapiens	IC50	=	180	nM	14980672
NPT148	Cell Line	HCT-15	Homo sapiens	IC50	=	70	nM	14980672
NPT784	Cell Line	MDA-MB-468	Homo sapiens	IC50	=	270	nM	14980672
NPT396	Cell Line	T47D	Homo sapiens	IC50	=	400	nM	14980672
NPT137	Cell Line	L1210	Mus musculus	ID50	=	3.10E-06	nM	3397995
NPT137	Cell Line	L1210	Mus musculus	ID50	=	1.82E-07	nM	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	89	%	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	52	%	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	2	%	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	1	%	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	98	%	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	100	%	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	73	%	3397995
NPT137	Cell Line	L1210	Mus musculus	Survival	=	7	%	3397995
NPT2831	Cell Line	P388/S	Mus musculus	IC50	=	48	nM	8544183
NPT552	Cell Line	P388/ADR	Mus musculus	IC50	=	535	nM	8544183
NPT4452	Cell Line	CCD 19Lu	Homo sapiens	IC50	=	2	ug/ml	10.1016/S0960-894X(97)00071-1
NPT168	Cell Line	P388	Mus musculus	IC50	=	0.01	ug/ml	10.1016/S0960-894X(97)00071-1
NPT4453	Cell Line	Lu-99 cell line		IC50	=	0.01	ug/ml	10.1016/S0960-894X(97)00071-1
NPT404	Cell Line	CCRF-CEM	Homo sapiens	IC50	=	0.02	ug/ml	10.1016/S0960-894X(97)00071-1
NPT317	Uncleic Acid	Nucleic Acid		IC50	=	13	nM	1906109
NPT317	Uncleic Acid	Nucleic Acid		IC50	=	14.8	nM	1906109
NPT317	Uncleic Acid	Nucleic Acid		IC50	=	32.2	nM	1906109
NPT168	Cell Line	P388	Mus musculus	IC50	=	50.8	nM	1906109
NPT168	Cell Line	P388	Mus musculus	IC50	=	0.06	ug/ml	9873721
NPT788	Cell Line	SNU1	Homo sapiens	IC50	=	2.32	ug/ml	9873721
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	590	nM	8021919
NPT1317	Cell Line	CCRF S-180	Mus musculus	ED50	=	1.7	mg/kg	8021919
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	270	nM	10.1016/0960-894X(96)00418-0
NPT2	Others	Unspecified		IC50	=	90	nM	10.1016/0960-894X(96)00418-0
NPT2	Others	Unspecified		Ratio	=	0.33		10.1016/0960-894X(96)00418-0
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	1100	nM	8021918
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	1400	nM	8021918
NPT32	Organism	Mus musculus	Mus musculus	ED50	=	3.7	mg/kg	8021918
NPT168	Cell Line	P388	Mus musculus	IC50	=	1.5	ug/ml	12620075
NPT4590	Cell Line	EL4	Mus musculus	IC50	=	3.94	ug/ml	12620075
NPT2609	Cell Line	BeWo	Homo sapiens	IC50	=	0.85	ug/ml	12620075
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	0.02	ug/ml	12620075
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	0.93	ug/ml	12620075
NPT32	Organism	Mus musculus	Mus musculus	ED50	=	1.6	mg/kg	7636865
NPT605	Organism	Homo sapiens	Homo sapiens	IC50	=	500	nM	11606141
NPT2319	Cell Line	A204	Homo sapiens	ID50	=	0.02	ug/ml	2500528
NPT1183	Cell Line	WiDr	Homo sapiens	ID50	=	0.031	ug/ml	2500528
NPT137	Cell Line	L1210	Mus musculus	ID50	=	0.031	ug/ml	2500528
NPT81	Cell Line	A549	Homo sapiens	IC50	=	0.47	ug/ml	2754710
NPT319	Cell Line	B16	Mus musculus	IC50	=	3.6	ug/ml	2754710
NPT319	Cell Line	B16	Mus musculus	IC50	=	1.5	ug/ml	2754710
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	1.1	ug/ml	2754710
NPT605	Organism	Homo sapiens	Homo sapiens	IC50	=	2.8	ug/ml	2754710
NPT2	Others	Unspecified		IC50	=	8.1	ug/ml	2754710
NPT2	Others	Unspecified		IC50	=	0.24	ug/ml	2754710
NPT81	Cell Line	A549	Homo sapiens	IC50	=	0.015	ug/ml	2754710
NPT81	Cell Line	A549	Homo sapiens	IC50	=	0.08	ug/ml	2754710
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	0.015	ug/ml	2754710
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	0.01	ug/ml	2754710
NPT3171	Cell Line	V79	Cricetulus griseus	IC50	=	800	nM	7966141
NPT3171	Cell Line	V79	Cricetulus griseus	IC50	=	400	nM	7966141
NPT3171	Cell Line	V79	Cricetulus griseus	Ratio	=	2		7966141
NPT3804	Cell Line	Human Tumor Cell lines		GI50	=	831.76	nM	15163210
NPT886	Cell Line	NIH3T3	Mus musculus	IC50	=	1700	nM	11855992
NPT886	Cell Line	NIH3T3	Mus musculus	Inhibition	=	88	%	11855992
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	50	nM	8709111
NPT4459	Cell Line	833K		IC50	=	328	nM	8709111
NPT134	Cell Line	SK-BR-3	Homo sapiens	IC50	=	993	nM	8709111
NPT2786	Cell Line	DC3F	Cricetulus griseus	IC50	=	82	nM	8709111
NPT4591	Cell Line	DC3F/AD-II	Cricetulus griseus	IC50	=	110	nM	8709111
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	810	nM	1495011
NPT4592	Cell Line	CHO-AA8	Cricetulus griseus	IC50	=	1.08	nM	2909741
NPT2	Others	Unspecified		Ratio	=	86		2909741
NPT2	Others	Unspecified		Ratio	=	2.35		2909741
NPT2	Others	Unspecified		Ratio	=	0.78		2909741
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	100	%	10.1016/S0960-894X(01)80148-7
NPT2	Others	Unspecified		Ratio	=	24		3091833
NPT4593	Cell Line	Clone 62		IC50	=	1500	nM	9276025
NPT4594	Cell Line	H2987 cell line		IC50	=	1600	nM	9276025
NPT179	Cell Line	A2780	Homo sapiens	IC50	=	50	nM	10698444
NPT571	Cell Line	A2780cisR	Homo sapiens	IC50	=	60	nM	10698444
NPT4595	Cell Line	CH1	Homo sapiens	IC50	=	40	nM	10698444
NPT146	Cell Line	SK-OV-3	Homo sapiens	IC50	=	200	nM	10698444
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	40	nM	10698444
NPT605	Organism	Homo sapiens	Homo sapiens	Inhibition	=	65	%	11311062
NPT2842	Cell Line	EMT6	Mus musculus	ED50	=	0.7	nM	7452674
NPT2842	Cell Line	EMT6	Mus musculus	ED50	=	0.001	nM	7452674
NPT2	Others	Unspecified		Ratio	=	700		7452674
NPT1183	Cell Line	WiDr	Homo sapiens	IC50	=	10	nM	1920349
NPT179	Cell Line	A2780	Homo sapiens	IC50	=	200	nM	1920349
NPT179	Cell Line	A2780	Homo sapiens	IC50	=	100	nM	1920349
NPT660	Cell Line	SW480	Homo sapiens	IC50	=	7	nM	1920349
NPT389	Cell Line	RPMI-8226	Homo sapiens	IC50	=	200	nM	1920349
NPT81	Cell Line	A549	Homo sapiens	IC50	=	0.08	ug/ml	11585450
NPT91	Cell Line	KB	Homo sapiens	IC50	=	0.1	ug/ml	11585450
NPT1535	Cell Line	U-87 MG	Homo sapiens	IC50	=	0.97	ug/ml	11585450
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	0.45	ug/ml	11585450
NPT180	Cell Line	HCT-8	Homo sapiens	IC50	=	0.15	ug/ml	11585450
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	1.55	ug/ml	11585450
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	0.36	ug/ml	11585450
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	8.4	mg/kg	8496913
NPT32	Organism	Mus musculus	Mus musculus	ED50	=	4.4	mg/kg	8496913
NPT111	Cell Line	K562	Homo sapiens	IC50	=	15.8	nM	12699386
NPT111	Cell Line	K562	Homo sapiens	IC50	=	1	nM	12699386
NPT137	Cell Line	L1210	Mus musculus	IC50	=	600	nM	10.1016/0960-894X(95)00353-U
NPT91	Cell Line	KB	Homo sapiens	IC50	=	400	nM	10.1016/0960-894X(95)00353-U
NPT2	Others	Unspecified		ID50	<	0.7	nM	11012027
NPT2	Others	Unspecified		ID50	=	2.66	nM	11012027
NPT83	Cell Line	MCF7	Homo sapiens	ID50	=	42.92	nM	11012027
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	67.9	%	10509925
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	52.69	%	10509925
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	79.24	%	10509925
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	63.49	%	10509925
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	70.1	%	10509925
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	87.54	%	10509925
NPT137	Cell Line	L1210	Mus musculus	IC50	=	600	nM	10.1016/S0960-894X(97)00100-5
NPT91	Cell Line	KB	Homo sapiens	IC50	=	400	nM	10.1016/S0960-894X(97)00100-5
NPT2	Others	Unspecified		IC50	=	525	nM	15743178
NPT2	Others	Unspecified		IC50	=	133	nM	15743178
NPT308	Cell Line	CAKI-1	Homo sapiens	IC50	=	251	nM	15743178
NPT308	Cell Line	CAKI-1	Homo sapiens	IC50	=	40	nM	15743178
NPT148	Cell Line	HCT-15	Homo sapiens	IG50	=	1.6	nM	16384701
NPT1872	Cell Line	Bcap37	Homo sapiens	IC50	=	2.33	ug/ml	16455245
NPT2170	Cell Line	RKO	Homo sapiens	IC50	=	1.75	ug/ml	16455245
NPT659	Cell Line	SMMC-7721	Homo sapiens	IC50	=	2.44	ug/ml	16455245
NPT111	Cell Line	K562	Homo sapiens	IC50	=	3.35	ug/ml	16455245
NPT447	Organism	Streptomyces	Streptomyces	IZ	=	30	mm	17506585
NPT168	Cell Line	P388	Mus musculus	IC50	=	0.15	ug/ml	17576066
NPT90	Cell Line	DU-145	Homo sapiens	Inhibition	=	56	%	17950603
NPT323	Cell Line	SW-620	Homo sapiens	Inhibition	=	67	%	17950603
NPT2	Others	Unspecified		Inhibition	=	84	%	17950603
NPT139	Cell Line	HT-29	Homo sapiens	Inhibition	=	86	%	17950603
NPT83	Cell Line	MCF7	Homo sapiens	Inhibition	=	78	%	17950603
NPT306	Cell Line	PC-3	Homo sapiens	EC50	=	140	nM	17950604
NPT81	Cell Line	A549	Homo sapiens	EC50	=	430	nM	17950604
NPT83	Cell Line	MCF7	Homo sapiens	EC50	=	960	nM	17950604
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	200	nM	18037301
NPT81	Cell Line	A549	Homo sapiens	IC50	=	400	nM	18037301
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	5000	nM	18037301
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	1200	nM	18037301
NPT81	Cell Line	A549	Homo sapiens	IC50	=	4500	nM	18037301
NPT81	Cell Line	A549	Homo sapiens	IC50	=	240	nM	18037301
NPT168	Cell Line	P388	Mus musculus	GI	=	43	%	10785435
NPT2	Others	Unspecified		IC50	=	3	ug/ml	11277765
NPT91	Cell Line	KB	Homo sapiens	IC50	=	0.01	ug/ml	12502326
NPT2	Others	Unspecified		IC50	=	0.01	ug/ml	12502326
NPT91	Cell Line	KB	Homo sapiens	IC50	=	0.01	ug/ml	11473432
NPT2	Others	Unspecified		IC50	=	0.01	ug/ml	11473432
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	10		17950497
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	13		17950497
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	11		17950497
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0		17950497
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	46.67	%	17950497
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	5.49	%	17950497
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	900	nM	18222567
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	2100	nM	18222567
NPT1171	Cell Line	HEp-2	Homo sapiens	GI	=	60	%	19201604
NPT407	Cell Line	COLO 205	Homo sapiens	GI	=	41	%	19201604
NPT323	Cell Line	SW-620	Homo sapiens	GI	=	29	%	19201604
NPT136	Cell Line	SK-N-SH	Homo sapiens	GI	=	85	%	19201604
NPT2	Others	Unspecified		Inhibition	=	100	%	18456372
NPT2	Others	Unspecified		GI50	=	100	nM	11473418
NPT2	Others	Unspecified		GI50	=	120	nM	11473418
NPT2	Others	Unspecified		GI50	=	23	nM	11473418
NPT2	Others	Unspecified		GI50	=	180	nM	11473418
NPT2	Others	Unspecified		GI50	=	64	nM	11473418
NPT2	Others	Unspecified		GI50	=	34	nM	11473418
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	200	nM	18752870
NPT81	Cell Line	A549	Homo sapiens	IC50	=	400	nM	18752870
NPT137	Cell Line	L1210	Mus musculus	IC50	=	0.02	ug/ml	12662110
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	0.015	ug/ml	12662110
NPT81	Cell Line	A549	Homo sapiens	IC50	=	0.02	ug/ml	12662110
NPT91	Cell Line	KB	Homo sapiens	IC50	=	0.015	ug/ml	12662110
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	0.01	ug/ml	9644081
NPT2	Others	Unspecified		IC50	=	0.01	ug/ml	9644081
NPT2	Others	Unspecified		ED50	=	0.1	ug/ml	16309320
NPT579	Cell Line	DLD-1	Homo sapiens	ED50	=	0.1	ug/ml	16309320
NPT91	Cell Line	KB	Homo sapiens	ED50	=	0.13	ug/ml	16309320
NPT168	Cell Line	P388	Mus musculus	Activity	=	43	%	15104507
NPT81	Cell Line	A549	Homo sapiens	GI	=	55	%	18707881
NPT90	Cell Line	DU-145	Homo sapiens	GI	=	63	%	18707881
NPT168	Cell Line	P388	Mus musculus	IC50	=	0.02	ug/ml	8254344
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	99	nM	2778449
NPT139	Cell Line	HT-29	Homo sapiens	IZ	=	10	mm	2778449
NPT168	Cell Line	P388	Mus musculus	IC50	=	3000	nM	2778449
NPT168	Cell Line	P388	Mus musculus	IZ	=	25	mm	2778449
NPT168	Cell Line	P388	Mus musculus	IZ	=	5	mm	2778449
NPT2	Others	Unspecified		ED50	=	20.2	nM	12880314
NPT2	Others	Unspecified		ED50	=	20.7	nM	12880314
NPT2	Others	Unspecified		ED50	=	0.019	nM	12880314
NPT2	Others	Unspecified		ED50	=	17.4	nM	12880314
NPT2	Others	Unspecified		ED50	=	0.049	nM	12880314
NPT3045	Cell Line	NUGC-4	Homo sapiens	ED50	=	19.1	nM	12880314
NPT2	Others	Unspecified		IC50	=	5	nM	18505284
NPT2	Others	Unspecified		IC50	=	400	nM	18505284
NPT2	Others	Unspecified		Ratio IC50	=	292		18505284
NPT180	Cell Line	HCT-8	Homo sapiens	IC50	=	83	nM	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	IC90	=	5700	nM	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	40.3	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	28.2	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	36.9	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	52.6	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	22.8	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	19.2	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	71.2	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	43.6	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	44	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	36.3	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	43.2	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	49.1	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	42.7	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	14.6	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	14.1	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	42.8	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	71.44	%	18845441
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	99	%	18845441
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	68	nM	11975488
NPT91	Cell Line	KB	Homo sapiens	ED50	=	0.56	ug/ml	16643051
NPT1183	Cell Line	WiDr	Homo sapiens	ED50	=	0.35	ug/ml	16643051
NPT2	Others	Unspecified		ED50	=	0.04	ug/ml	16643051
NPT81	Cell Line	A549	Homo sapiens	IC50	=	300	nM	16038545
NPT91	Cell Line	KB	Homo sapiens	IC50	=	600	nM	16038545
NPT180	Cell Line	HCT-8	Homo sapiens	IC50	=	600	nM	16038545
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	1500	nM	16038545
NPT1184	Cell Line	Daoy	Homo sapiens	ED50	=	0.21	nM	19061391
NPT1183	Cell Line	WiDr	Homo sapiens	ED50	=	0.18	nM	19061391
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	1500	nM	19432411
NPT659	Cell Line	SMMC-7721	Homo sapiens	IC50	=	5400	nM	19432411
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	3300	nM	19432411
NPT317	Uncleic Acid	Nucleic Acid		Activity	=	76.5	%	19576785
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	8.4	ug/ml	19540628
NPT1317	Cell Line	CCRF S-180	Mus musculus	ED50	=	4.4	ug/ml	19540628
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	1500	nM	19939522
NPT1171	Cell Line	HEp-2	Homo sapiens	IC50	=	1500	nM	19939522
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	41	%	19939522
NPT407	Cell Line	COLO 205	Homo sapiens	GI	=	44	%	19939522
NPT377	Cell Line	OVCAR-3	Homo sapiens	GI	=	65	%	19939522
NPT1171	Cell Line	HEp-2	Homo sapiens	GI	=	58	%	19926172
NPT407	Cell Line	COLO 205	Homo sapiens	GI	=	4	%	19926172
NPT2	Others	Unspecified		GI	=	44	%	19926172
NPT148	Cell Line	HCT-15	Homo sapiens	GI	=	25	%	19926172
NPT81	Cell Line	A549	Homo sapiens	GI	=	40	%	19926172
NPT744	Cell Line	IMR-32	Homo sapiens	GI	=	85	%	19926172
NPT306	Cell Line	PC-3	Homo sapiens	EC50	=	140	nM	19674905
NPT81	Cell Line	A549	Homo sapiens	EC50	=	430	nM	19674905
NPT83	Cell Line	MCF7	Homo sapiens	EC50	=	960	nM	19674905
NPT611	Cell Line	Hepatocyte	Homo sapiens	EC50	=	1460	nM	19674905
NPT83	Cell Line	MCF7	Homo sapiens	ED50	=	0.14	ug/ml	20144547
NPT1183	Cell Line	WiDr	Homo sapiens	ED50	=	0.15	ug/ml	20144547
NPT1171	Cell Line	HEp-2	Homo sapiens	ED50	=	0.07	ug/ml	20144547
NPT1184	Cell Line	Daoy	Homo sapiens	ED50	=	0.14	ug/ml	20144547
NPT111	Cell Line	K562	Homo sapiens	IC50	=	470	nM	20117936
NPT2	Others	Unspecified		IC50	=	2750	nM	20117936
NPT464	Cell Line	Daudi	Homo sapiens	IC50	=	450	nM	20117936
NPT927	Cell Line	PBMC	Homo sapiens	IC50	=	4030	nM	20117936
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	53	%	20188544
NPT399	Cell Line	SF-295	Homo sapiens	GI	=	43	%	20188544
NPT2	Others	Unspecified		Inhibition	=	100	%	20133022
NPT2	Others	Unspecified		IC50	=	460	nM	20605274
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	270	nM	20605274
NPT90	Cell Line	DU-145	Homo sapiens	IC50	=	170	nM	20605274
NPT2	Others	Unspecified		Inhibition	=	55.39	%	21074431
NPT407	Cell Line	COLO 205	Homo sapiens	Inhibition	=	56.27	%	21074431
NPT133	Cell Line	ZR-75-1	Homo sapiens	Inhibition	=	51.26	%	21074431
NPT116	Cell Line	HL-60	Homo sapiens	Inhibition	=	53.21	%	21074431
NPT165	Cell Line	HeLa	Homo sapiens	Inhibition	=	56.48	%	21074431
NPT2	Others	Unspecified		IC50	=	39580	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	=	1299.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		CC50	>	40000	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50	>	74890	nM	PubChem BioAssay data set
NPT19	Organism	Escherichia coli	Escherichia coli	FC	=	2.6		19029320
NPT19	Organism	Escherichia coli	Escherichia coli	FC	=	2.8		19029320
NPT19	Organism	Escherichia coli	Escherichia coli	FC	=	8.2		19029320
NPT19	Organism	Escherichia coli	Escherichia coli	FC	=	7.9		19029320
NPT19	Organism	Escherichia coli	Escherichia coli	FC	=	0.9		19029320
NPT19	Organism	Escherichia coli	Escherichia coli	FC	=	2		19029320
NPT19	Organism	Escherichia coli	Escherichia coli	FC	=	1		19029320
NPT165	Cell Line	HeLa	Homo sapiens	ED50	=	0.2	ug/ml	21115251
NPT83	Cell Line	MCF7	Homo sapiens	ED50	=	0.1	ug/ml	21115251
NPT1171	Cell Line	HEp-2	Homo sapiens	ED50	=	0.1	ug/ml	21115251
NPT1184	Cell Line	Daoy	Homo sapiens	ED50	=	0.1	ug/ml	21115251
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	1500	nM	20968296
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	5400	nM	20968296
NPT152	Individual Protein	Nuclear factor erythroid 2-related factor 2	Homo sapiens	Potency		3662.6	nM	PubChem BioAssay data set
NPT1171	Cell Line	HEp-2	Homo sapiens	GI	=	31	%	21482109
NPT317	Uncleic Acid	Nucleic Acid		Activity	=	3	%	21658959
NPT317	Uncleic Acid	Nucleic Acid		Activity	=	2	%	21658959
NPT2	Others	Unspecified		GI	=	100	%	21875796
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	Potency		5221.3	nM	PubChem BioAssay data set
NPT8	Individual Protein	DNA polymerase iota	Homo sapiens	Potency		89125.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		3981.1	nM	PubChem BioAssay data set
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	Potency		13115.4	nM	PubChem BioAssay data set
NPT91	Cell Line	KB	Homo sapiens	IC50	=	0.08	ug/ml	22014827
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	0.06	ug/ml	22014827
NPT1184	Cell Line	Daoy	Homo sapiens	IC50	=	0.05	ug/ml	22014827
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	60	%	22071256
NPT1171	Cell Line	HEp-2	Homo sapiens	GI	=	7	%	22047801
NPT81	Cell Line	A549	Homo sapiens	GI	=	34	%	22047801
NPT90	Cell Line	DU-145	Homo sapiens	GI	=	44	%	22047801
NPT2	Others	Unspecified		Activity	=	5.49	%	22142614
NPT2	Others	Unspecified		Activity	=	7.29	%	22142614
NPT2	Others	Unspecified		Activity	=	15.8	%	22142614
NPT2	Others	Unspecified		Activity	=	24.9	%	22142614
NPT2	Others	Unspecified		Activity	=	30.5	%	22142614
NPT2	Others	Unspecified		Activity	=	75.1	%	22142614
NPT139	Cell Line	HT-29	Homo sapiens	GI	=	60	%	22123322
NPT323	Cell Line	SW-620	Homo sapiens	GI	=	55	%	22123322
NPT407	Cell Line	COLO 205	Homo sapiens	GI	=	43	%	22123322
NPT1171	Cell Line	HEp-2	Homo sapiens	GI	=	58	%	22123322
NPT90	Cell Line	DU-145	Homo sapiens	GI	=	48	%	22123322
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	55	%	22123322
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	70	%	22245048
NPT1171	Cell Line	HEp-2	Homo sapiens	GI	=	78	%	22245048
NPT368	Cell Line	SN12C	Homo sapiens	GI50		286.42	nM	PubChem BioAssay data set
NPT367	Cell Line	MDA-N	Homo sapiens	GI50		1702.16	nM	PubChem BioAssay data set
NPT370	Cell Line	NCI-H23	Homo sapiens	GI50		129.42	nM	PubChem BioAssay data set
NPT371	Cell Line	UO-31	Homo sapiens	GI50		1866.38	nM	PubChem BioAssay data set
NPT369	Cell Line	ACHN	Homo sapiens	GI50		147.91	nM	PubChem BioAssay data set
NPT116	Cell Line	HL-60	Homo sapiens	GI50		203.7	nM	PubChem BioAssay data set
NPT372	Cell Line	HOP-92	Homo sapiens	GI50		3491.4	nM	PubChem BioAssay data set
NPT90	Cell Line	DU-145	Homo sapiens	GI50		158.49	nM	PubChem BioAssay data set
NPT374	Cell Line	SF-539	Homo sapiens	GI50		243.78	nM	PubChem BioAssay data set
NPT373	Cell Line	SK-MEL-5	Homo sapiens	GI50		334.97	nM	PubChem BioAssay data set
NPT375	Cell Line	Malme-3M	Homo sapiens	GI50		796.16	nM	PubChem BioAssay data set
NPT376	Cell Line	A498	Homo sapiens	GI50		714.5	nM	PubChem BioAssay data set
NPT111	Cell Line	K562	Homo sapiens	GI50		2027.68	nM	PubChem BioAssay data set
NPT377	Cell Line	OVCAR-3	Homo sapiens	GI50		3069.02	nM	PubChem BioAssay data set
NPT112	Cell Line	MOLT-4	Homo sapiens	GI50		229.61	nM	PubChem BioAssay data set
NPT379	Cell Line	HOP-62	Homo sapiens	GI50		95.72	nM	PubChem BioAssay data set
NPT380	Cell Line	U-251	Homo sapiens	GI50		354	nM	PubChem BioAssay data set
NPT378	Cell Line	NCI/ADR-RES	Homo sapiens	GI50		4742.42	nM	PubChem BioAssay data set
NPT382	Cell Line	OVCAR-5	Homo sapiens	GI50		1358.31	nM	PubChem BioAssay data set
NPT381	Cell Line	OVCAR-8	Homo sapiens	GI50		1106.62	nM	PubChem BioAssay data set
NPT572	Cell Line	DMS-273	Homo sapiens	GI50		104.23	nM	PubChem BioAssay data set
NPT383	Cell Line	SNB-19	Homo sapiens	GI50		295.8	nM	PubChem BioAssay data set
NPT385	Cell Line	SR	Homo sapiens	GI50		121.62	nM	PubChem BioAssay data set
NPT82	Cell Line	MDA-MB-231	Homo sapiens	GI50		5714.79	nM	PubChem BioAssay data set
NPT323	Cell Line	SW-620	Homo sapiens	GI50		485.29	nM	PubChem BioAssay data set
NPT573	Cell Line	M19-MEL	Homo sapiens	GI50		613.76	nM	PubChem BioAssay data set
NPT384	Cell Line	TK-10	Homo sapiens	GI50		4864.07	nM	PubChem BioAssay data set
NPT455	Cell Line	NCI-H522	Homo sapiens	GI50		666.81	nM	PubChem BioAssay data set
NPT386	Cell Line	KM12	Homo sapiens	GI50		2218.2	nM	PubChem BioAssay data set
NPT574	Cell Line	XF498	Homo sapiens	GI50		1127.2	nM	PubChem BioAssay data set
NPT387	Cell Line	M14	Homo sapiens	GI50		379.31	nM	PubChem BioAssay data set
NPT389	Cell Line	RPMI-8226	Homo sapiens	GI50		2404.36	nM	PubChem BioAssay data set
NPT388	Cell Line	NCI-H322M	Homo sapiens	GI50		995.41	nM	PubChem BioAssay data set
NPT456	Cell Line	OVCAR-4	Homo sapiens	GI50		3564.51	nM	PubChem BioAssay data set
NPT168	Cell Line	P388	Mus musculus	GI50		181.13	nM	PubChem BioAssay data set
NPT390	Cell Line	LOX IMVI	Homo sapiens	GI50		266.69	nM	PubChem BioAssay data set
NPT457	Cell Line	BT-549	Homo sapiens	GI50		1745.82	nM	PubChem BioAssay data set
NPT147	Cell Line	SK-MEL-2	Homo sapiens	GI50		1648.16	nM	PubChem BioAssay data set
NPT81	Cell Line	A549	Homo sapiens	GI50		165.58	nM	PubChem BioAssay data set
NPT575	Cell Line	KM-20L2	Homo sapiens	GI50		1297.18	nM	PubChem BioAssay data set
NPT391	Cell Line	HCC 2998	Homo sapiens	GI50		613.76	nM	PubChem BioAssay data set
NPT392	Cell Line	SNB-75	Homo sapiens	GI50		447.71	nM	PubChem BioAssay data set
NPT148	Cell Line	HCT-15	Homo sapiens	GI50		1291.22	nM	PubChem BioAssay data set
NPT395	Cell Line	SF-268	Homo sapiens	GI50		490.91	nM	PubChem BioAssay data set
NPT393	Cell Line	HCT-116	Homo sapiens	GI50		701.46	nM	PubChem BioAssay data set
NPT394	Cell Line	EKVX	Homo sapiens	GI50		4623.81	nM	PubChem BioAssay data set
NPT83	Cell Line	MCF7	Homo sapiens	GI50		148.25	nM	PubChem BioAssay data set
NPT576	Cell Line	DMS-114	Homo sapiens	GI50		421.7	nM	PubChem BioAssay data set
NPT306	Cell Line	PC-3	Homo sapiens	GI50		2243.88	nM	PubChem BioAssay data set
NPT731	Cell Line	LXFL 529	Homo sapiens	GI50		2552.7	nM	PubChem BioAssay data set
NPT146	Cell Line	SK-OV-3	Homo sapiens	GI50		1016.25	nM	PubChem BioAssay data set
NPT396	Cell Line	T47D	Homo sapiens	GI50		2023.02	nM	PubChem BioAssay data set
NPT397	Cell Line	NCI-H460	Homo sapiens	GI50		17.95	nM	PubChem BioAssay data set
NPT398	Cell Line	UACC-62	Homo sapiens	GI50		131.22	nM	PubChem BioAssay data set
NPT308	Cell Line	CAKI-1	Homo sapiens	GI50		267.92	nM	PubChem BioAssay data set
NPT400	Cell Line	MDA-MB-435	Homo sapiens	GI50		1737.8	nM	PubChem BioAssay data set
NPT552	Cell Line	P388/ADR	Mus musculus	GI50		1386.76	nM	PubChem BioAssay data set
NPT458	Cell Line	IGROV-1	Homo sapiens	GI50		2904.02	nM	PubChem BioAssay data set
NPT399	Cell Line	SF-295	Homo sapiens	GI50		166.72	nM	PubChem BioAssay data set
NPT577	Cell Line	RXF 631	Homo sapiens	GI50		1124.6	nM	PubChem BioAssay data set
NPT402	Cell Line	Hs-578T	Homo sapiens	GI50		3221.07	nM	PubChem BioAssay data set
NPT403	Cell Line	UACC-257	Homo sapiens	GI50		1207.81	nM	PubChem BioAssay data set
NPT578	Cell Line	SNB-78	Homo sapiens	GI50		5345.64	nM	PubChem BioAssay data set
NPT401	Cell Line	786-0	Homo sapiens	GI50		403.65	nM	PubChem BioAssay data set
NPT404	Cell Line	CCRF-CEM	Homo sapiens	GI50		229.09	nM	PubChem BioAssay data set
NPT579	Cell Line	DLD-1	Homo sapiens	GI50		2798.98	nM	PubChem BioAssay data set
NPT405	Cell Line	NCI-H226	Homo sapiens	GI50		714.5	nM	PubChem BioAssay data set
NPT170	Cell Line	SK-MEL-28	Homo sapiens	GI50		1749.85	nM	PubChem BioAssay data set
NPT139	Cell Line	HT-29	Homo sapiens	GI50		758.58	nM	PubChem BioAssay data set
NPT406	Cell Line	RXF 393	Homo sapiens	GI50		2009.09	nM	PubChem BioAssay data set
NPT407	Cell Line	COLO 205	Homo sapiens	GI50		1020.94	nM	PubChem BioAssay data set
NPT738	Cell Line	SN12K1	Homo sapiens	GI50		959.4	nM	PubChem BioAssay data set
NPT732	Cell Line	HOP-18	Homo sapiens	GI50		1099.01	nM	PubChem BioAssay data set
NPT90	Cell Line	DU-145	Homo sapiens	IC50	=	170	nM	22522008
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	270	nM	22522008
NPT2	Others	Unspecified		IC50	=	460	nM	22522008
NPT2	Others	Unspecified		Inhibition	=	100	%	22541394
NPT165	Cell Line	HeLa	Homo sapiens	ED50	=	0.13	ug/ml	22672798
NPT1171	Cell Line	HEp-2	Homo sapiens	ED50	=	0.12	ug/ml	22672798
NPT1184	Cell Line	Daoy	Homo sapiens	ED50	=	0.08	ug/ml	22672798
NPT83	Cell Line	MCF7	Homo sapiens	ED50	=	0.09	ug/ml	22672798
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	100	nM	22537363
NPT81	Cell Line	A549	Homo sapiens	IC50	=	3000	nM	22545792
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	60	%	22818042
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	1800	nM	22642381
NPT659	Cell Line	SMMC-7721	Homo sapiens	IC50	=	5600	nM	22642381
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	3400	nM	22642381
NPT83	Cell Line	MCF7	Homo sapiens	GI	=	82	%	22982123
NPT81	Cell Line	A549	Homo sapiens	GI	=	70	%	22982123
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	70	%	22982123
NPT10	Individual Protein	Geminin	Homo sapiens	Potency		10322.5	nM	PubChem BioAssay data set
NPT4599	Cell Line	S9	Homo sapiens	Activity	=	11.25	%	21353728
NPT66	Individual Protein	Acetylcholinesterase	Electrophorus electricus	Inhibition	=	4.01	%	23062825
NPT67	Individual Protein	Cholinesterase	Equus caballus	Inhibition	=	3.34	%	23062825
NPT81	Cell Line	A549	Homo sapiens	Activity	=	2.4	ug/ml	23123017
NPT81	Cell Line	A549	Homo sapiens	Activity	=	2.6	ug/ml	23123017
NPT81	Cell Line	A549	Homo sapiens	Activity	=	3.3	ug/ml	23123017
NPT81	Cell Line	A549	Homo sapiens	Activity	=	4.3	ug/ml	23123017
NPT81	Cell Line	A549	Homo sapiens	IC50	=	400	nM	23123017
NPT83	Cell Line	MCF7	Homo sapiens	GI	=	65	%	10.1007/s00044-011-9887-7
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	58	%	10.1007/s00044-011-9887-7
NPT90	Cell Line	DU-145	Homo sapiens	IC50	=	1800	nM	10.1007/s00044-010-9500-5
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	1400	nM	10.1007/s00044-010-9500-5
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	61	%	10.1007/s00044-010-9410-6
NPT458	Cell Line	IGROV-1	Homo sapiens	GI	=	47	%	10.1007/s00044-010-9410-6
NPT399	Cell Line	SF-295	Homo sapiens	GI	=	43	%	10.1007/s00044-010-9410-6
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	61	%	10.1007/s00044-012-0106-y
NPT382	Cell Line	OVCAR-5	Homo sapiens	GI	=	71	%	10.1007/s00044-012-0032-z
NPT83	Cell Line	MCF7	Homo sapiens	GI	=	82	%	10.1007/s00044-012-0032-z
NPT1970	Cell Line	THP-1	Homo sapiens	IC50	=	1500	nM	10.1007/s00044-012-0424-0
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	1500	nM	10.1007/s00044-012-0424-0
NPT81	Cell Line	A549	Homo sapiens	IC50	=	400	nM	10.1007/s00044-012-0424-0
NPT1970	Cell Line	THP-1	Homo sapiens	GI	=	65	%	10.1007/s00044-012-0312-7
NPT306	Cell Line	PC-3	Homo sapiens	GI	=	68	%	23419739
NPT306	Cell Line	PC-3	Homo sapiens	Activity	=	59	%	23387901
NPT81	Cell Line	A549	Homo sapiens	IC50	=	0.54	ug/ml	23451797
NPT453	Cell Line	HT-1080	Homo sapiens	IC50	=	0.15	ug/ml	23451797
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	0.14	ug/ml	23451797
NPT1078	Individual Protein	Indoleamine 2,3-dioxygenase	Homo sapiens	Ki	=	25000	nM	23218716
NPT2	Others	Unspecified		Potency		9.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		730.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		580.5	nM	PubChem BioAssay data set
NPT2268	Cell Line	DOK	Homo sapiens	IC50	=	5155.1	nM	10.6019/CHEMBL1201861
NPT1899	Cell Line	DSH1	Homo sapiens	IC50	=	96.53	nM	10.6019/CHEMBL1201861
NPT4600	Cell Line	DV-90	Homo sapiens	IC50	=	2921.43	nM	10.6019/CHEMBL1201861
NPT1184	Cell Line	Daoy	Homo sapiens	IC50	=	88.01	nM	10.6019/CHEMBL1201861
NPT464	Cell Line	Daudi	Homo sapiens	IC50	=	392.42	nM	10.6019/CHEMBL1201861
NPT90	Cell Line	DU-145	Homo sapiens	IC50	=	6.519	nM	10.6019/CHEMBL1201861
NPT1900	Cell Line	DU-4475	Homo sapiens	IC50	=	47.47	nM	10.6019/CHEMBL1201861
NPT4601	Cell Line	EHEB	Homo sapiens	IC50	=	672.13	nM	10.6019/CHEMBL1201861
NPT394	Cell Line	EKVX	Homo sapiens	IC50	=	893	nM	10.6019/CHEMBL1201861
NPT1901	Cell Line	EM-2	Homo sapiens	IC50	=	1033.74	nM	10.6019/CHEMBL1201861
NPT1902	Cell Line	ES1	Homo sapiens	IC50	=	7.288	nM	10.6019/CHEMBL1201861
NPT1905	Cell Line	ES4	Homo sapiens	IC50	=	1.555	nM	10.6019/CHEMBL1201861
NPT1903	Cell Line	ES5	Homo sapiens	IC50	=	102.42	nM	10.6019/CHEMBL1201861
NPT1904	Cell Line	ES3	Homo sapiens	IC50	=	7.882	nM	10.6019/CHEMBL1201861
NPT2270	Cell Line	Detroit562	Homo sapiens	IC50	=	170.26	nM	10.6019/CHEMBL1201861
NPT2271	Cell Line	DoTc2-4510	Homo sapiens	IC50	=	180.37	nM	10.6019/CHEMBL1201861
NPT1906	Cell Line	EB-3	Homo sapiens	IC50	=	3197.68	nM	10.6019/CHEMBL1201861
NPT1907	Cell Line	EB2	Homo sapiens	IC50	=	65.36	nM	10.6019/CHEMBL1201861
NPT1908	Cell Line	EC-GI-10	Homo sapiens	IC50	=	14913.25	nM	10.6019/CHEMBL1201861
NPT1910	Cell Line	ECC4	Homo sapiens	IC50	=	5070.36	nM	10.6019/CHEMBL1201861
NPT4602	Cell Line	EFE-184	Homo sapiens	IC50	=	1381.25	nM	10.6019/CHEMBL1201861
NPT2272	Cell Line	EFM-19	Homo sapiens	IC50	=	2088.96	nM	10.6019/CHEMBL1201861
NPT2273	Cell Line	EFO-21	Homo sapiens	IC50	=	591.14	nM	10.6019/CHEMBL1201861
NPT2274	Cell Line	EFO-27	Homo sapiens	IC50	=	1131.22	nM	10.6019/CHEMBL1201861
NPT2275	Cell Line	EGI-1	Homo sapiens	IC50	=	2390.59	nM	10.6019/CHEMBL1201861
NPT376	Cell Line	A498	Homo sapiens	IC50	=	376968.26	nM	10.6019/CHEMBL1201861
NPT2276	Cell Line	A673	Homo sapiens	IC50	=	789.6	nM	10.6019/CHEMBL1201861
NPT2277	Cell Line	C-33-A	Homo sapiens	IC50	=	486.87	nM	10.6019/CHEMBL1201861
NPT4603	Cell Line	C-4-II	Homo sapiens	IC50	=	103.51	nM	10.6019/CHEMBL1201861
NPT2279	Cell Line	COLO-792	Homo sapiens	IC50	=	1502.64	nM	10.6019/CHEMBL1201861
NPT1912	Cell Line	COLO-800	Homo sapiens	IC50	=	78.66	nM	10.6019/CHEMBL1201861
NPT1189	Cell Line	DG-75	Homo sapiens	IC50	=	6249.4	nM	10.6019/CHEMBL1201861
NPT1913	Cell Line	DJM-1	Homo sapiens	IC50	=	1033.04	nM	10.6019/CHEMBL1201861
NPT2280	Cell Line	A704	Homo sapiens	IC50	=	2383.11	nM	10.6019/CHEMBL1201861
NPT2281	Cell Line	ABC-1	Homo sapiens	IC50	=	61.2	nM	10.6019/CHEMBL1201861
NPT1911	Cell Line	C2BBe1	Homo sapiens	IC50	=	9284	nM	10.6019/CHEMBL1201861
NPT2282	Cell Line	C32	Homo sapiens	IC50	=	1528.34	nM	10.6019/CHEMBL1201861
NPT2284	Cell Line	C3A	Homo sapiens	IC50	=	194.31	nM	10.6019/CHEMBL1201861
NPT1914	Cell Line	COLO-824	Homo sapiens	IC50	=	1444.61	nM	10.6019/CHEMBL1201861
NPT2283	Cell Line	DK-MG	Homo sapiens	IC50	=	21667.01	nM	10.6019/CHEMBL1201861
NPT576	Cell Line	DMS-114	Homo sapiens	IC50	=	2086.92	nM	10.6019/CHEMBL1201861
NPT369	Cell Line	ACHN	Homo sapiens	IC50	=	72.08	nM	10.6019/CHEMBL1201861
NPT1916	Cell Line	ACN	Homo sapiens	IC50	=	127.91	nM	10.6019/CHEMBL1201861
NPT1452	Cell Line	C8166	Homo sapiens	IC50	=	932.32	nM	10.6019/CHEMBL1201861
NPT1915	Cell Line	COLO-829	Homo sapiens	IC50	=	2086.84	nM	10.6019/CHEMBL1201861
NPT2285	Cell Line	COR-L105	Homo sapiens	IC50	=	1613.17	nM	10.6019/CHEMBL1201861
NPT2287	Cell Line	COR-L23	Homo sapiens	IC50	=	240.94	nM	10.6019/CHEMBL1201861
NPT1918	Cell Line	DMS-79	Homo sapiens	IC50	=	2471.63	nM	10.6019/CHEMBL1201861
NPT1919	Cell Line	DOHH-2	Homo sapiens	IC50	=	93.83	nM	10.6019/CHEMBL1201861
NPT196	Cell Line	AGS	Homo sapiens	IC50	=	105.8	nM	10.6019/CHEMBL1201861
NPT1920	Cell Line	ALL-PO	Homo sapiens	IC50	=	30.98	nM	10.6019/CHEMBL1201861
NPT1917	Cell Line	CA46	Homo sapiens	IC50	=	1019.8	nM	10.6019/CHEMBL1201861
NPT308	Cell Line	CAKI-1	Homo sapiens	IC50	=	23.32	nM	10.6019/CHEMBL1201861
NPT2286	Cell Line	CAL-120	Homo sapiens	IC50	=	5963.51	nM	10.6019/CHEMBL1201861
NPT2289	Cell Line	CAL-12T	Homo sapiens	IC50	=	491.25	nM	10.6019/CHEMBL1201861
NPT1921	Cell Line	COR-L279	Homo sapiens	IC50	=	5.545	nM	10.6019/CHEMBL1201861
NPT1922	Cell Line	COR-L88	Homo sapiens	IC50	=	319.14	nM	10.6019/CHEMBL1201861
NPT1923	Cell Line	DMS-153	Homo sapiens	IC50	=	425.26	nM	10.6019/CHEMBL1201861
NPT572	Cell Line	DMS-273	Homo sapiens	IC50	=	160.83	nM	10.6019/CHEMBL1201861
NPT4604	Cell Line	DMS-53	Homo sapiens	IC50	=	808.56	nM	10.6019/CHEMBL1201861
NPT1924	Cell Line	AM-38	Homo sapiens	IC50	=	221.16	nM	10.6019/CHEMBL1201861
NPT2288	Cell Line	AN3-CA	Homo sapiens	IC50	=	523.28	nM	10.6019/CHEMBL1201861
NPT1925	Cell Line	CAL-148	Homo sapiens	IC50	=	17.83	nM	10.6019/CHEMBL1201861
NPT2290	Cell Line	CAL-27	Homo sapiens	IC50	=	41.18	nM	10.6019/CHEMBL1201861
NPT2291	Cell Line	CP50-MEL-B	Homo sapiens	IC50	=	780.03	nM	10.6019/CHEMBL1201861
NPT1926	Cell Line	CP66-MEL	Homo sapiens	IC50	=	644.95	nM	10.6019/CHEMBL1201861
NPT1629	Cell Line	CWR22R	Homo sapiens	IC50	=	144.07	nM	10.6019/CHEMBL1201861
NPT1927	Cell Line	ARH-77	Homo sapiens	IC50	=	243.31	nM	10.6019/CHEMBL1201861
NPT1928	Cell Line	ATN-1	Homo sapiens	IC50	=	17.39	nM	10.6019/CHEMBL1201861
NPT2296	Cell Line	AU565	Homo sapiens	IC50	=	500.96	nM	10.6019/CHEMBL1201861
NPT2292	Cell Line	CAL-33	Homo sapiens	IC50	=	536.53	nM	10.6019/CHEMBL1201861
NPT2293	Cell Line	CAL-39	Homo sapiens	IC50	=	46.49	nM	10.6019/CHEMBL1201861
NPT2299	Cell Line	CAL-51	Homo sapiens	IC50	=	30.86	nM	10.6019/CHEMBL1201861
NPT1929	Cell Line	CPC-N	Homo sapiens	IC50	=	380.66	nM	10.6019/CHEMBL1201861
NPT1930	Cell Line	CTB-1	Homo sapiens	IC50	=	306.37	nM	10.6019/CHEMBL1201861
NPT2294	Cell Line	23132-87	Homo sapiens	IC50	=	30.53	nM	10.6019/CHEMBL1201861
NPT2295	Cell Line	5637	Homo sapiens	IC50	=	31.93	nM	10.6019/CHEMBL1201861
NPT2302	Cell Line	639-V	Homo sapiens	IC50	=	1.759	nM	10.6019/CHEMBL1201861
NPT2297	Cell Line	ASPC1	Homo sapiens	IC50	=	2898.55	nM	10.6019/CHEMBL1201861
NPT2300	Cell Line	CAL-54	Homo sapiens	IC50	=	1841.48	nM	10.6019/CHEMBL1201861
NPT2301	Cell Line	CAL-62	Homo sapiens	IC50	=	241.85	nM	10.6019/CHEMBL1201861
NPT1932	Cell Line	CTV-1	Homo sapiens	IC50	=	18.67	nM	10.6019/CHEMBL1201861
NPT1933	Cell Line	CW-2	Homo sapiens	IC50	=	7727.58	nM	10.6019/CHEMBL1201861
NPT2303	Cell Line	647-V	Homo sapiens	IC50	=	87.39	nM	10.6019/CHEMBL1201861
NPT1094	Cell Line	697	Homo sapiens	IC50	=	0.1283	nM	10.6019/CHEMBL1201861
NPT1931	Cell Line	BB30-HNC	Homo sapiens	IC50	=	30.61	nM	10.6019/CHEMBL1201861
NPT1934	Cell Line	BB49-HNC	Homo sapiens	IC50	=	352.52	nM	10.6019/CHEMBL1201861
NPT2304	Cell Line	CAL-72	Homo sapiens	IC50	=	46733.86	nM	10.6019/CHEMBL1201861
NPT2305	Cell Line	CAL-85-1	Homo sapiens	IC50	=	65.88	nM	10.6019/CHEMBL1201861
NPT2308	Cell Line	CAMA-1	Homo sapiens	IC50	=	540.59	nM	10.6019/CHEMBL1201861
NPT2306	Cell Line	Ca-Ski	Homo sapiens	IC50	=	53.75	nM	10.6019/CHEMBL1201861
NPT1031	Cell Line	Ca9-22	Homo sapiens	IC50	=	155.57	nM	10.6019/CHEMBL1201861
NPT2310	Cell Line	CaR-1	Homo sapiens	IC50	=	468.78	nM	10.6019/CHEMBL1201861
NPT2307	Cell Line	769-P	Homo sapiens	IC50	=	7.112	nM	10.6019/CHEMBL1201861
NPT401	Cell Line	786-0	Homo sapiens	IC50	=	14.01	nM	10.6019/CHEMBL1201861
NPT1935	Cell Line	BB65-RCC	Homo sapiens	IC50	=	144.71	nM	10.6019/CHEMBL1201861
NPT929	Cell Line	BC1 cell line		IC50	=	88.81	nM	10.6019/CHEMBL1201861
NPT2309	Cell Line	CAPAN-1	Homo sapiens	IC50	=	116.4	nM	10.6019/CHEMBL1201861
NPT1937	Cell Line	CAS-1	Homo sapiens	IC50	=	3381.85	nM	10.6019/CHEMBL1201861
NPT1307	Cell Line	Calu-1	Homo sapiens	IC50	=	4807.2	nM	10.6019/CHEMBL1201861
NPT2311	Cell Line	Calu-3	Homo sapiens	IC50	=	320.95	nM	10.6019/CHEMBL1201861
NPT1939	Cell Line	8-MG-BA	Homo sapiens	IC50	=	104	nM	10.6019/CHEMBL1201861
NPT2312	Cell Line	8305C	Homo sapiens	IC50	=	155.75	nM	10.6019/CHEMBL1201861
NPT1936	Cell Line	BC-3	Homo sapiens	IC50	=	212.08	nM	10.6019/CHEMBL1201861
NPT2313	Cell Line	BCPAP	Homo sapiens	IC50	=	239.6	nM	10.6019/CHEMBL1201861
NPT1940	Cell Line	BE-13	Homo sapiens	IC50	=	0.1673	nM	10.6019/CHEMBL1201861
NPT4605	Cell Line	CCF-STTG1	Homo sapiens	IC50	=	215.59	nM	10.6019/CHEMBL1201861
NPT404	Cell Line	CCRF-CEM	Homo sapiens	IC50	=	61.68	nM	10.6019/CHEMBL1201861
NPT1938	Cell Line	Calu-6	Homo sapiens	IC50	=	319.71	nM	10.6019/CHEMBL1201861
NPT4458	Cell Line	Caov-3 cell line		IC50	=	161.72	nM	10.6019/CHEMBL1201861
NPT1313	Cell Line	Capan-2	Homo sapiens	IC50	=	2785.28	nM	10.6019/CHEMBL1201861
NPT1215	Cell Line	8505C	Homo sapiens	IC50	=	429.83	nM	10.6019/CHEMBL1201861
NPT1941	Cell Line	A101D	Homo sapiens	IC50	=	257.45	nM	10.6019/CHEMBL1201861
NPT2314	Cell Line	BEN	Homo sapiens	IC50	=	935.16	nM	10.6019/CHEMBL1201861
NPT2315	Cell Line	BFTC-905	Homo sapiens	IC50	=	92.69	nM	10.6019/CHEMBL1201861
NPT1942	Cell Line	CESS	Homo sapiens	IC50	=	225.4	nM	10.6019/CHEMBL1201861
NPT1943	Cell Line	CGTH-W-1	Homo sapiens	IC50	=	38.74	nM	10.6019/CHEMBL1201861
NPT2317	Cell Line	ChaGo-K-1	Homo sapiens	IC50	=	1910.33	nM	10.6019/CHEMBL1201861
NPT2318	Cell Line	A172	Homo sapiens	IC50	=	537.52	nM	10.6019/CHEMBL1201861
NPT2319	Cell Line	A204	Homo sapiens	IC50	=	84.19	nM	10.6019/CHEMBL1201861
NPT1383	Cell Line	A2058	Homo sapiens	IC50	=	115.1	nM	10.6019/CHEMBL1201861
NPT2320	Cell Line	BFTC-909	Homo sapiens	IC50	=	85.27	nM	10.6019/CHEMBL1201861
NPT2321	Cell Line	BHT-101	Homo sapiens	IC50	=	1740.29	nM	10.6019/CHEMBL1201861
NPT2323	Cell Line	BHY	Homo sapiens	IC50	=	75.28	nM	10.6019/CHEMBL1201861
NPT2322	Cell Line	CHL-1	Homo sapiens	IC50	=	225.16	nM	10.6019/CHEMBL1201861
NPT1945	Cell Line	CHP-126	Homo sapiens	IC50	=	72.44	nM	10.6019/CHEMBL1201861
NPT1946	Cell Line	D-263MG	Homo sapiens	IC50	=	540.04	nM	10.6019/CHEMBL1201861
NPT1947	Cell Line	D283 Med		IC50	=	220.69	nM	10.6019/CHEMBL1201861
NPT1948	Cell Line	A253 cell line		IC50	=	345.64	nM	10.6019/CHEMBL1201861
NPT179	Cell Line	A2780	Homo sapiens	IC50	=	106.63	nM	10.6019/CHEMBL1201861
NPT1949	Cell Line	BL-41	Homo sapiens	IC50	=	294.9	nM	10.6019/CHEMBL1201861
NPT1950	Cell Line	BL-70	Homo sapiens	IC50	=	1276.67	nM	10.6019/CHEMBL1201861
NPT2324	Cell Line	CHP-212	Homo sapiens	IC50	=	4.368	nM	10.6019/CHEMBL1201861
NPT1951	Cell Line	CMK	Homo sapiens	IC50	=	5.827	nM	10.6019/CHEMBL1201861
NPT407	Cell Line	COLO 205	Homo sapiens	IC50	=	14.33	nM	10.6019/CHEMBL1201861
NPT1954	Cell Line	D-392MG	Homo sapiens	IC50	=	6684.51	nM	10.6019/CHEMBL1201861
NPT1955	Cell Line	A3-KAW	Homo sapiens	IC50	=	34.96	nM	10.6019/CHEMBL1201861
NPT1083	Cell Line	A-375	Homo sapiens	IC50	=	139.42	nM	10.6019/CHEMBL1201861
NPT4606	Cell Line	BOKU	Homo sapiens	IC50	=	103.78	nM	10.6019/CHEMBL1201861
NPT2325	Cell Line	BPH-1	Homo sapiens	IC50	=	29.9	nM	10.6019/CHEMBL1201861
NPT2326	Cell Line	BT-20	Homo sapiens	IC50	=	311.97	nM	10.6019/CHEMBL1201861
NPT1952	Cell Line	COLO-320-HSR	Homo sapiens	IC50	=	1079.2	nM	10.6019/CHEMBL1201861
NPT1956	Cell Line	COLO-668	Homo sapiens	IC50	=	7.545	nM	10.6019/CHEMBL1201861
NPT1957	Cell Line	D-502MG	Homo sapiens	IC50	=	84724.26	nM	10.6019/CHEMBL1201861
NPT1958	Cell Line	A388	Homo sapiens	IC50	=	207.22	nM	10.6019/CHEMBL1201861
NPT1959	Cell Line	A4-Fuk	Homo sapiens	IC50	=	225.43	nM	10.6019/CHEMBL1201861
NPT845	Cell Line	BT-474	Homo sapiens	IC50	=	2623.26	nM	10.6019/CHEMBL1201861
NPT2328	Cell Line	COLO-678	Homo sapiens	IC50	=	2886.91	nM	10.6019/CHEMBL1201861
NPT2329	Cell Line	COLO-679	Homo sapiens	IC50	=	90.25	nM	10.6019/CHEMBL1201861
NPT2332	Cell Line	COLO-680N	Homo sapiens	IC50	=	244.1	nM	10.6019/CHEMBL1201861
NPT1961	Cell Line	D-542MG	Homo sapiens	IC50	=	601.65	nM	10.6019/CHEMBL1201861
NPT1962	Cell Line	DB	Homo sapiens	IC50	=	429.95	nM	10.6019/CHEMBL1201861
NPT2331	Cell Line	A-427	Homo sapiens	IC50	=	301.33	nM	10.6019/CHEMBL1201861
NPT762	Cell Line	A-431	Homo sapiens	IC50	=	43.77	nM	10.6019/CHEMBL1201861
NPT1960	Cell Line	BV-173	Homo sapiens	IC50	=	6.067	nM	10.6019/CHEMBL1201861
NPT1963	Cell Line	Becker	Homo sapiens	IC50	=	862.32	nM	10.6019/CHEMBL1201861
NPT1081	Cell Line	BXPC-3	Homo sapiens	IC50	=	774.78	nM	10.6019/CHEMBL1201861
NPT1964	Cell Line	COLO-684	Homo sapiens	IC50	=	799.3	nM	10.6019/CHEMBL1201861
NPT2278	Cell Line	COLO-741	Homo sapiens	IC50	=	2199.28	nM	10.6019/CHEMBL1201861
NPT2333	Cell Line	DBTRG-05MG	Homo sapiens	IC50	=	570.26	nM	10.6019/CHEMBL1201861
NPT1965	Cell Line	DEL	Homo sapiens	IC50	=	48.39	nM	10.6019/CHEMBL1201861
NPT1966	Cell Line	NCI-H1838	Homo sapiens	IC50	=	404.19	nM	10.6019/CHEMBL1201861
NPT1967	Cell Line	NCI-H526	Homo sapiens	IC50	=	67.37	nM	10.6019/CHEMBL1201861
NPT2335	Cell Line	NCI-H596		IC50	=	1537.7	nM	10.6019/CHEMBL1201861
NPT2337	Cell Line	OE33	Homo sapiens	IC50	=	337.8	nM	10.6019/CHEMBL1201861
NPT1968	Cell Line	OMC-1	Homo sapiens	IC50	=	389.55	nM	10.6019/CHEMBL1201861
NPT2200	Cell Line	RPMI-6666	Homo sapiens	IC50	=	219.61	nM	10.6019/CHEMBL1201861
NPT1091	Cell Line	RPMI-7951	Homo sapiens	IC50	=	167.55	nM	10.6019/CHEMBL1201861
NPT389	Cell Line	RPMI-8226	Homo sapiens	IC50	=	1238.47	nM	10.6019/CHEMBL1201861
NPT926	Cell Line	SK-MEL-1	Homo sapiens	IC50	=	1888.15	nM	10.6019/CHEMBL1201861
NPT1312	Cell Line	SW1990	Homo sapiens	IC50	=	637.05	nM	10.6019/CHEMBL1201861
NPT2338	Cell Line	SW48	Homo sapiens	IC50	=	193.36	nM	10.6019/CHEMBL1201861
NPT323	Cell Line	SW-620	Homo sapiens	IC50	=	39.79	nM	10.6019/CHEMBL1201861
NPT1969	Cell Line	TGW	Homo sapiens	IC50	=	2758.03	nM	10.6019/CHEMBL1201861
NPT1970	Cell Line	THP-1	Homo sapiens	IC50	=	595.5	nM	10.6019/CHEMBL1201861
NPT1971	Cell Line	GI-1	Homo sapiens	IC50	=	35.16	nM	10.6019/CHEMBL1201861
NPT1972	Cell Line	GI-ME-N	Homo sapiens	IC50	=	1390.89	nM	10.6019/CHEMBL1201861
NPT2204	Cell Line	HH	Homo sapiens	IC50	=	1073.8	nM	10.6019/CHEMBL1201861
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	106.06	nM	10.6019/CHEMBL1201861
NPT2348	Cell Line	HLE	Homo sapiens	IC50	=	498.32	nM	10.6019/CHEMBL1201861
NPT1973	Cell Line	IST-SL1	Homo sapiens	IC50	=	1446.2	nM	10.6019/CHEMBL1201861
NPT1974	Cell Line	IST-SL2	Homo sapiens	IC50	=	387.62	nM	10.6019/CHEMBL1201861
NPT1975	Cell Line	KS-1	Homo sapiens	IC50	=	364.15	nM	10.6019/CHEMBL1201861
NPT2340	Cell Line	KU-19-19	Homo sapiens	IC50	=	3358.35	nM	10.6019/CHEMBL1201861
NPT1976	Cell Line	LNCaP-Clone-FGC	Homo sapiens	IC50	=	450.08	nM	10.6019/CHEMBL1201861
NPT1977	Cell Line	LOUCY	Homo sapiens	IC50	=	26.19	nM	10.6019/CHEMBL1201861
NPT2209	Cell Line	MFH-ino	Homo sapiens	IC50	=	70.61	nM	10.6019/CHEMBL1201861
NPT1978	Cell Line	MFM-223	Homo sapiens	IC50	=	10380.73	nM	10.6019/CHEMBL1201861
NPT1979	Cell Line	NB13	Homo sapiens	IC50	=	646.03	nM	10.6019/CHEMBL1201861
NPT639	Cell Line	NCI-H187	Homo sapiens	IC50	=	707.99	nM	10.6019/CHEMBL1201861
NPT1981	Cell Line	NCI-H1882	Homo sapiens	IC50	=	257.09	nM	10.6019/CHEMBL1201861
NPT1982	Cell Line	NCI-H1963	Homo sapiens	IC50	=	974.37	nM	10.6019/CHEMBL1201861
NPT2353	Cell Line	NCI-H1993	Homo sapiens	IC50	=	22984.02	nM	10.6019/CHEMBL1201861
NPT1983	Cell Line	NCI-H64	Homo sapiens	IC50	=	1534.44	nM	10.6019/CHEMBL1201861
NPT2343	Cell Line	NCI-H650	Homo sapiens	IC50	=	344.07	nM	10.6019/CHEMBL1201861
NPT1984	Cell Line	ONS-76	Homo sapiens	IC50	=	329.56	nM	10.6019/CHEMBL1201861
NPT1986	Cell Line	RPMI 8402	Homo sapiens	IC50	=	17.13	nM	10.6019/CHEMBL1201861
NPT1987	Cell Line	RPMI-8866	Homo sapiens	IC50	=	1317.77	nM	10.6019/CHEMBL1201861
NPT147	Cell Line	SK-MEL-2	Homo sapiens	IC50	=	3974.64	nM	10.6019/CHEMBL1201861
NPT2344	Cell Line	SK-MEL-24	Homo sapiens	IC50	=	1374.23	nM	10.6019/CHEMBL1201861
NPT170	Cell Line	SK-MEL-28	Homo sapiens	IC50	=	18973.1	nM	10.6019/CHEMBL1201861
NPT2345	Cell Line	SW626	Homo sapiens	IC50	=	286.22	nM	10.6019/CHEMBL1201861
NPT1988	Cell Line	SW684	Homo sapiens	IC50	=	112568.06	nM	10.6019/CHEMBL1201861
NPT384	Cell Line	TK-10	Homo sapiens	IC50	=	528.32	nM	10.6019/CHEMBL1201861
NPT4607	Cell Line	TT	Homo sapiens	IC50	=	3677.75	nM	10.6019/CHEMBL1201861
NPT2347	Cell Line	GMS-10	Homo sapiens	IC50	=	3838.07	nM	10.6019/CHEMBL1201861
NPT1989	Cell Line	GOTO	Homo sapiens	IC50	=	553.71	nM	10.6019/CHEMBL1201861
NPT2349	Cell Line	HMV-2 cell line		IC50	=	166.06	nM	10.6019/CHEMBL1201861
NPT2350	Cell Line	HN	Homo sapiens	IC50	=	782.54	nM	10.6019/CHEMBL1201861
NPT1990	Cell Line	J-RT3-T3-5	Homo sapiens	IC50	=	185.8	nM	10.6019/CHEMBL1201861
NPT1505	Cell Line	J82	Homo sapiens	IC50	=	0.119	nM	10.6019/CHEMBL1201861
NPT1991	Cell Line	KU812 cell line		IC50	=	149.96	nM	10.6019/CHEMBL1201861
NPT1992	Cell Line	KURAMOCHI	Homo sapiens	IC50	=	523.44	nM	10.6019/CHEMBL1201861
NPT390	Cell Line	LOX IMVI	Homo sapiens	IC50	=	352.5	nM	10.6019/CHEMBL1201861
NPT1993	Cell Line	LP-1	Homo sapiens	IC50	=	4559.67	nM	10.6019/CHEMBL1201861
NPT2351	Cell Line	MG-63	Homo sapiens	IC50	=	226.18	nM	10.6019/CHEMBL1201861
NPT1994	Cell Line	MHH-CALL-2	Homo sapiens	IC50	=	6.06	nM	10.6019/CHEMBL1201861
NPT2352	Cell Line	MHH-ES-1	Homo sapiens	IC50	=	16.26	nM	10.6019/CHEMBL1201861
NPT1996	Cell Line	NB5	Homo sapiens	IC50	=	357.9	nM	10.6019/CHEMBL1201861
NPT2354	Cell Line	NCI-H2009	Homo sapiens	IC50	=	288.57	nM	10.6019/CHEMBL1201861
NPT2368	Cell Line	NCI-H2030	Homo sapiens	IC50	=	211.32	nM	10.6019/CHEMBL1201861
NPT2356	Cell Line	NCI-H661	Homo sapiens	IC50	=	541.58	nM	10.6019/CHEMBL1201861
NPT1396	Cell Line	NCI-H69	Homo sapiens	IC50	=	1678.82	nM	10.6019/CHEMBL1201861
NPT1985	Cell Line	OPM-2	Homo sapiens	IC50	=	6348.57	nM	10.6019/CHEMBL1201861
NPT1997	Cell Line	OS-RC-2	Homo sapiens	IC50	=	263.7	nM	10.6019/CHEMBL1201861
NPT377	Cell Line	OVCAR-3	Homo sapiens	IC50	=	1127.87	nM	10.6019/CHEMBL1201861
NPT1998	Cell Line	RS4-11	Homo sapiens	IC50	=	34.86	nM	10.6019/CHEMBL1201861
NPT2357	Cell Line	RT-112	Homo sapiens	IC50	=	177.98	nM	10.6019/CHEMBL1201861
NPT2358	Cell Line	SK-MEL3	Homo sapiens	IC50	=	711.12	nM	10.6019/CHEMBL1201861
NPT2359	Cell Line	SK-MEL-30	Homo sapiens	IC50	=	474.31	nM	10.6019/CHEMBL1201861
NPT2360	Cell Line	SW756	Homo sapiens	IC50	=	596.91	nM	10.6019/CHEMBL1201861
NPT2361	Cell Line	SW780	Homo sapiens	IC50	=	438758	nM	10.6019/CHEMBL1201861
NPT1999	Cell Line	TUR	Homo sapiens	IC50	=	189.67	nM	10.6019/CHEMBL1201861
NPT2362	Cell Line	TYK-nu	Homo sapiens	IC50	=	58.73	nM	10.6019/CHEMBL1201861
NPT2363	Cell Line	U-118-MG	Homo sapiens	IC50	=	3142.84	nM	10.6019/CHEMBL1201861
NPT2364	Cell Line	GP5d	Homo sapiens	IC50	=	84	nM	10.6019/CHEMBL1201861
NPT2000	Cell Line	GR-ST	Homo sapiens	IC50	=	121.34	nM	10.6019/CHEMBL1201861
NPT2365	Cell Line	HO-1-N-1	Homo sapiens	IC50	=	440.64	nM	10.6019/CHEMBL1201861
NPT379	Cell Line	HOP-62	Homo sapiens	IC50	=	20.2	nM	10.6019/CHEMBL1201861
NPT2001	Cell Line	JAR	Homo sapiens	IC50	=	4563.84	nM	10.6019/CHEMBL1201861
NPT2366	Cell Line	JEG-3	Homo sapiens	IC50	=	2231.91	nM	10.6019/CHEMBL1201861
NPT2002	Cell Line	KY821	Homo sapiens	IC50	=	1650.78	nM	10.6019/CHEMBL1201861
NPT2367	Cell Line	KYSE-140	Homo sapiens	IC50	=	381.34	nM	10.6019/CHEMBL1201861
NPT2003	Cell Line	LS-1034	Homo sapiens	IC50	=	30.16	nM	10.6019/CHEMBL1201861
NPT2004	Cell Line	LS-123	Homo sapiens	IC50	=	1720.01	nM	10.6019/CHEMBL1201861
NPT2005	Cell Line	MHH-NB-11	Homo sapiens	IC50	=	192.55	nM	10.6019/CHEMBL1201861
NPT2006	Cell Line	MHH-PREB-1	Homo sapiens	IC50	=	3147.35	nM	10.6019/CHEMBL1201861
NPT2007	Cell Line	NB6	Homo sapiens	IC50	=	2233.52	nM	10.6019/CHEMBL1201861
NPT2369	Cell Line	NCI-H2052	Homo sapiens	IC50	=	1988.12	nM	10.6019/CHEMBL1201861
NPT2009	Cell Line	NCI-H2081	Homo sapiens	IC50	=	740.57	nM	10.6019/CHEMBL1201861
NPT2010	Cell Line	NCI-H716	Homo sapiens	IC50	=	2820.42	nM	10.6019/CHEMBL1201861
NPT2011	Cell Line	NCI-H719	Homo sapiens	IC50	=	35.12	nM	10.6019/CHEMBL1201861
NPT2012	Cell Line	NCI-H720	Homo sapiens	IC50	=	1544.25	nM	10.6019/CHEMBL1201861
NPT456	Cell Line	OVCAR-4	Homo sapiens	IC50	=	696.91	nM	10.6019/CHEMBL1201861
NPT382	Cell Line	OVCAR-5	Homo sapiens	IC50	=	487.11	nM	10.6019/CHEMBL1201861
NPT4608	Cell Line	RT-4	Homo sapiens	IC50	=	1699.23	nM	10.6019/CHEMBL1201861
NPT2370	Cell Line	RVH-421	Homo sapiens	IC50	=	629.17	nM	10.6019/CHEMBL1201861
NPT406	Cell Line	RXF 393	Homo sapiens	IC50	=	4389.75	nM	10.6019/CHEMBL1201861
NPT1506	Cell Line	SK-MES-1	Homo sapiens	IC50	=	51.12	nM	10.6019/CHEMBL1201861
NPT2013	Cell Line	SK-MM-2	Homo sapiens	IC50	=	2716.95	nM	10.6019/CHEMBL1201861
NPT2380	Cell Line	SK-N-AS	Homo sapiens	IC50	=	1790.73	nM	10.6019/CHEMBL1201861
NPT2371	Cell Line	SW837	Homo sapiens	IC50	=	276.13	nM	10.6019/CHEMBL1201861
NPT2014	Cell Line	SW872	Homo sapiens	IC50	=	0.676	nM	10.6019/CHEMBL1201861
NPT1045	Cell Line	U2OS	Homo sapiens	IC50	=	23698.65	nM	10.6019/CHEMBL1201861
NPT2015	Cell Line	U-266	Homo sapiens	IC50	=	866.18	nM	10.6019/CHEMBL1201861
NPT2016	Cell Line	ES6	Homo sapiens	IC50	=	745.62	nM	10.6019/CHEMBL1201861
NPT2017	Cell Line	ES7	Homo sapiens	IC50	=	3.653	nM	10.6019/CHEMBL1201861
NPT2018	Cell Line	GT3TKB	Homo sapiens	IC50	=	318.23	nM	10.6019/CHEMBL1201861
NPT372	Cell Line	HOP-92	Homo sapiens	IC50	=	1936.58	nM	10.6019/CHEMBL1201861
NPT307	Cell Line	HOS	Homo sapiens	IC50	=	106.7	nM	10.6019/CHEMBL1201861
NPT2384	Cell Line	HPAF-II	Homo sapiens	IC50	=	1097.15	nM	10.6019/CHEMBL1201861
NPT2019	Cell Line	JVM-2	Homo sapiens	IC50	=	397.34	nM	10.6019/CHEMBL1201861
NPT2020	Cell Line	JVM-3	Homo sapiens	IC50	=	2647.52	nM	10.6019/CHEMBL1201861
NPT2373	Cell Line	KYSE-150 cell line		IC50	=	34.09	nM	10.6019/CHEMBL1201861
NPT2374	Cell Line	KYSE-180	Homo sapiens	IC50	=	202.19	nM	10.6019/CHEMBL1201861
NPT2021	Cell Line	LS-411N	Homo sapiens	IC50	=	321.76	nM	10.6019/CHEMBL1201861
NPT2022	Cell Line	LS-513	Homo sapiens	IC50	=	1178.08	nM	10.6019/CHEMBL1201861
NPT783	Cell Line	MIA PaCa-2	Homo sapiens	IC50	=	275.45	nM	10.6019/CHEMBL1201861
NPT2375	Cell Line	MKN-1	Homo sapiens	IC50	=	540.81	nM	10.6019/CHEMBL1201861
NPT2008	Cell Line	NB69	Homo sapiens	IC50	=	175.06	nM	10.6019/CHEMBL1201861
NPT2377	Cell Line	NCI-H2087	Homo sapiens	IC50	=	85.69	nM	10.6019/CHEMBL1201861
NPT2024	Cell Line	NCI-H209	Homo sapiens	IC50	=	6.168	nM	10.6019/CHEMBL1201861
NPT2378	Cell Line	NCI-H727	Homo sapiens	IC50	=	211.8	nM	10.6019/CHEMBL1201861
NPT2025	Cell Line	NCI-H747	Homo sapiens	IC50	=	411.59	nM	10.6019/CHEMBL1201861
NPT381	Cell Line	OVCAR-8	Homo sapiens	IC50	=	175.54	nM	10.6019/CHEMBL1201861
NPT2379	Cell Line	P12-Ichikawa	Homo sapiens	IC50	=	4.787	nM	10.6019/CHEMBL1201861
NPT80	Cell Line	Raji	Homo sapiens	IC50	=	1220.94	nM	10.6019/CHEMBL1201861
NPT2026	Cell Line	Ramos-2G6-4C10	Homo sapiens	IC50	=	2545.72	nM	10.6019/CHEMBL1201861
NPT2027	Cell Line	SK-N-DZ	Homo sapiens	IC50	=	2389.58	nM	10.6019/CHEMBL1201861
NPT2382	Cell Line	SW948	Homo sapiens	IC50	=	3752.81	nM	10.6019/CHEMBL1201861
NPT2029	Cell Line	SW 954	Homo sapiens	IC50	=	44.91	nM	10.6019/CHEMBL1201861
NPT2030	Cell Line	U-698-M	Homo sapiens	IC50	=	1602.91	nM	10.6019/CHEMBL1201861
NPT1535	Cell Line	U-87 MG	Homo sapiens	IC50	=	1273.72	nM	10.6019/CHEMBL1201861
NPT2031	Cell Line	ES8	Homo sapiens	IC50	=	1.712	nM	10.6019/CHEMBL1201861
NPT2383	Cell Line	ESS-1	Homo sapiens	IC50	=	13.92	nM	10.6019/CHEMBL1201861
NPT1892	Cell Line	H4	Rattus norvegicus	IC50	=	12.44	nM	10.6019/CHEMBL1201861
NPT2032	Cell Line	HAL-01	Homo sapiens	IC50	=	15.73	nM	10.6019/CHEMBL1201861
NPT924	Cell Line	HSC-2	Homo sapiens	IC50	=	83.42	nM	10.6019/CHEMBL1201861
NPT2385	Cell Line	HSC-3	Homo sapiens	IC50	=	75.54	nM	10.6019/CHEMBL1201861
NPT2033	Cell Line	JIYOYE	Homo sapiens	IC50	=	629.54	nM	10.6019/CHEMBL1201861
NPT111	Cell Line	K562	Homo sapiens	IC50	=	1978.69	nM	10.6019/CHEMBL1201861
NPT2386	Cell Line	KYSE-270	Homo sapiens	IC50	=	102.84	nM	10.6019/CHEMBL1201861
NPT2387	Cell Line	KYSE-410	Homo sapiens	IC50	=	583.59	nM	10.6019/CHEMBL1201861
NPT2395	Cell Line	KYSE-450	Homo sapiens	IC50	=	563.11	nM	10.6019/CHEMBL1201861
NPT2034	Cell Line	LU-134-A	Homo sapiens	IC50	=	46.72	nM	10.6019/CHEMBL1201861
NPT1179	Cell Line	MKN-28	Homo sapiens	IC50	=	230.09	nM	10.6019/CHEMBL1201861
NPT1097	Cell Line	MKN-45	Homo sapiens	IC50	=	165.04	nM	10.6019/CHEMBL1201861
NPT2398	Cell Line	MKN-7	Homo sapiens	IC50	=	27856.21	nM	10.6019/CHEMBL1201861
NPT2035	Cell Line	NCCIT	Homo sapiens	IC50	=	1010.24	nM	10.6019/CHEMBL1201861
NPT2036	Cell Line	NCI-H1092	Homo sapiens	IC50	=	3279.9	nM	10.6019/CHEMBL1201861
NPT2390	Cell Line	NCI-H2122	Homo sapiens	IC50	=	13.96	nM	10.6019/CHEMBL1201861
NPT1082	Cell Line	NCI-H2126	Homo sapiens	IC50	=	260.2	nM	10.6019/CHEMBL1201861
NPT2038	Cell Line	NCI-H748	Homo sapiens	IC50	=	59.54	nM	10.6019/CHEMBL1201861
NPT2391	Cell Line	NCI-H810	Homo sapiens	IC50	=	251.61	nM	10.6019/CHEMBL1201861
NPT2040	Cell Line	P30-OHK	Homo sapiens	IC50	=	4.842	nM	10.6019/CHEMBL1201861
NPT2041	Cell Line	P31-FUJ	Homo sapiens	IC50	=	3457.75	nM	10.6019/CHEMBL1201861
NPT2400	Cell Line	PA-1	Homo sapiens	IC50	=	23.51	nM	10.6019/CHEMBL1201861
NPT2392	Cell Line	S-117	Homo sapiens	IC50	=	592.44	nM	10.6019/CHEMBL1201861
NPT2393	Cell Line	SAS	Homo sapiens	IC50	=	614.65	nM	10.6019/CHEMBL1201861
NPT2028	Cell Line	SK-N-FI	Homo sapiens	IC50	=	39707.5	nM	10.6019/CHEMBL1201861
NPT2043	Cell Line	SK-NEP-1	Homo sapiens	IC50	=	166.53	nM	10.6019/CHEMBL1201861
NPT2044	Cell Line	SW 962	Homo sapiens	IC50	=	157.55	nM	10.6019/CHEMBL1201861
NPT371	Cell Line	UO-31	Homo sapiens	IC50	=	365.8	nM	10.6019/CHEMBL1201861
NPT380	Cell Line	U-251	Homo sapiens	IC50	=	128.73	nM	10.6019/CHEMBL1201861
NPT2045	Cell Line	ETK-1	Homo sapiens	IC50	=	108.24	nM	10.6019/CHEMBL1201861
NPT2047	Cell Line	HC-1	Homo sapiens	IC50	=	156.51	nM	10.6019/CHEMBL1201861
NPT4609	Cell Line	HCC1143	Homo sapiens	IC50	=	1066.4	nM	10.6019/CHEMBL1201861
NPT2048	Cell Line	HCC1187	Homo sapiens	IC50	=	8921.3	nM	10.6019/CHEMBL1201861
NPT2394	Cell Line	HSC-4	Homo sapiens	IC50	=	434.45	nM	10.6019/CHEMBL1201861
NPT2049	Cell Line	HT	Homo sapiens	IC50	=	1536.59	nM	10.6019/CHEMBL1201861
NPT2050	Cell Line	K052	Homo sapiens	IC50	=	149.34	nM	10.6019/CHEMBL1201861
NPT2051	Cell Line	K5	Homo sapiens	IC50	=	1783.98	nM	10.6019/CHEMBL1201861
NPT2396	Cell Line	KYSE-510	Homo sapiens	IC50	=	0.1486	nM	10.6019/CHEMBL1201861
NPT2397	Cell Line	KYSE-520 cell line		IC50	=	772.18	nM	10.6019/CHEMBL1201861
NPT2053	Cell Line	LU-139	Homo sapiens	IC50	=	1218.41	nM	10.6019/CHEMBL1201861
NPT2054	Cell Line	LU-165	Homo sapiens	IC50	=	513.11	nM	10.6019/CHEMBL1201861
NPT2055	Cell Line	ML-2	Homo sapiens	IC50	=	8.781	nM	10.6019/CHEMBL1201861
NPT2057	Cell Line	NCI-H1155	Homo sapiens	IC50	=	873.36	nM	10.6019/CHEMBL1201861
NPT2410	Cell Line	NCI-H1299	Homo sapiens	IC50	=	218.41	nM	10.6019/CHEMBL1201861
NPT2059	Cell Line	NCI-H2141	Homo sapiens	IC50	=	852.81	nM	10.6019/CHEMBL1201861
NPT2399	Cell Line	NCI-H2170	Homo sapiens	IC50	=	0.1513	nM	10.6019/CHEMBL1201861
NPT2039	Cell Line	NCI-H82	Homo sapiens	IC50	=	2801.93	nM	10.6019/CHEMBL1201861
NPT4610	Cell Line	NCI-H838	Homo sapiens	IC50	=	1232.91	nM	10.6019/CHEMBL1201861
NPT2061	Cell Line	NCI-H889	Homo sapiens	IC50	=	2483.42	nM	10.6019/CHEMBL1201861
NPT2401	Cell Line	PANC-03-27	Homo sapiens	IC50	=	167.16	nM	10.6019/CHEMBL1201861
NPT2402	Cell Line	PANC-08-13	Homo sapiens	IC50	=	2397.77	nM	10.6019/CHEMBL1201861
NPT2042	Cell Line	SBC-1	Homo sapiens	IC50	=	447.7	nM	10.6019/CHEMBL1201861
NPT2403	Cell Line	SBC-5	Homo sapiens	IC50	=	2.589	nM	10.6019/CHEMBL1201861
NPT146	Cell Line	SK-OV-3	Homo sapiens	IC50	=	142.64	nM	10.6019/CHEMBL1201861
NPT2063	Cell Line	SK-PN-DW	Homo sapiens	IC50	=	63.76	nM	10.6019/CHEMBL1201861
NPT2404	Cell Line	SW982	Homo sapiens	IC50	=	104.73	nM	10.6019/CHEMBL1201861
NPT2405	Cell Line	SAOS-2	Homo sapiens	IC50	=	1406.49	nM	10.6019/CHEMBL1201861
NPT2245	Cell Line	SiHa	Homo sapiens	IC50	=	1893.4	nM	10.6019/CHEMBL1201861
NPT403	Cell Line	UACC-257	Homo sapiens	IC50	=	1565.66	nM	10.6019/CHEMBL1201861
NPT398	Cell Line	UACC-62	Homo sapiens	IC50	=	2155.33	nM	10.6019/CHEMBL1201861
NPT2064	Cell Line	UACC-812	Homo sapiens	IC50	=	16830.61	nM	10.6019/CHEMBL1201861
NPT2046	Cell Line	EVSA-T	Homo sapiens	IC50	=	1573.68	nM	10.6019/CHEMBL1201861
NPT2065	Cell Line	EW-1	Homo sapiens	IC50	=	88.07	nM	10.6019/CHEMBL1201861
NPT2066	Cell Line	EW-11	Homo sapiens	IC50	=	513.36	nM	10.6019/CHEMBL1201861
NPT2406	Cell Line	HCC1395	Homo sapiens	IC50	=	1057.54	nM	10.6019/CHEMBL1201861
NPT2407	Cell Line	HCC1419	Homo sapiens	IC50	=	3484.02	nM	10.6019/CHEMBL1201861
NPT453	Cell Line	HT-1080	Homo sapiens	IC50	=	353.71	nM	10.6019/CHEMBL1201861
NPT658	Cell Line	HT1197	Homo sapiens	IC50	=	2021.74	nM	10.6019/CHEMBL1201861
NPT2419	Cell Line	HT-1376	Homo sapiens	IC50	=	967.11	nM	10.6019/CHEMBL1201861
NPT2052	Cell Line	KALS-1	Homo sapiens	IC50	=	129.14	nM	10.6019/CHEMBL1201861
NPT2067	Cell Line	KARPAS-299	Homo sapiens	IC50	=	1416.51	nM	10.6019/CHEMBL1201861
NPT2408	Cell Line	KYSE-70 cell line		IC50	=	224.31	nM	10.6019/CHEMBL1201861
NPT2068	Cell Line	L-363	Homo sapiens	IC50	=	434.17	nM	10.6019/CHEMBL1201861
NPT2069	Cell Line	Lu-65	Homo sapiens	IC50	=	1012.47	nM	10.6019/CHEMBL1201861
NPT2409	Cell Line	LU-99A	Homo sapiens	IC50	=	224.24	nM	10.6019/CHEMBL1201861
NPT2056	Cell Line	MLMA	Homo sapiens	IC50	=	1309.78	nM	10.6019/CHEMBL1201861
NPT2071	Cell Line	MMAC-SF	Homo sapiens	IC50	=	1011.63	nM	10.6019/CHEMBL1201861
NPT2073	Cell Line	NCI-H1304	Homo sapiens	IC50	=	375.23	nM	10.6019/CHEMBL1201861
NPT2060	Cell Line	NCI-H2171	Homo sapiens	IC50	=	1497.85	nM	10.6019/CHEMBL1201861
NPT2075	Cell Line	NCI-H2196	Homo sapiens	IC50	=	886	nM	10.6019/CHEMBL1201861
NPT2076	Cell Line	NCI-H2227	Homo sapiens	IC50	=	6323.64	nM	10.6019/CHEMBL1201861
NPT2411	Cell Line	NCI-H2228	Homo sapiens	IC50	=	0.7963	nM	10.6019/CHEMBL1201861
NPT465	Cell Line	NCI-N87	Homo sapiens	IC50	=	438.12	nM	10.6019/CHEMBL1201861
NPT788	Cell Line	SNU1	Homo sapiens	IC50	=	156.24	nM	10.6019/CHEMBL1201861
NPT2412	Cell Line	Panc1005	Homo sapiens	IC50	=	73.75	nM	10.6019/CHEMBL1201861
NPT2413	Cell Line	PC-14	Homo sapiens	IC50	=	491.27	nM	10.6019/CHEMBL1201861
NPT2062	Cell Line	SCC-15	Homo sapiens	IC50	=	863.86	nM	10.6019/CHEMBL1201861
NPT2414	Cell Line	SCC-25	Homo sapiens	IC50	=	870.36	nM	10.6019/CHEMBL1201861
NPT2078	Cell Line	SK-UT-1	Homo sapiens	IC50	=	82.8	nM	10.6019/CHEMBL1201861
NPT2415	Cell Line	SKG-IIIa	Homo sapiens	IC50	=	377.38	nM	10.6019/CHEMBL1201861
NPT550	Cell Line	T-24	Homo sapiens	IC50	=	245.77	nM	10.6019/CHEMBL1201861
NPT396	Cell Line	T47D	Homo sapiens	IC50	=	6371.91	nM	10.6019/CHEMBL1201861
NPT2416	Cell Line	UACC-893	Homo sapiens	IC50	=	418.01	nM	10.6019/CHEMBL1201861
NPT2417	Cell Line	UMUC3	Homo sapiens	IC50	=	101.83	nM	10.6019/CHEMBL1201861
NPT2425	Cell Line	UMC-11	Homo sapiens	IC50	=	567.01	nM	10.6019/CHEMBL1201861
NPT2080	Cell Line	EW-13	Homo sapiens	IC50	=	52.51	nM	10.6019/CHEMBL1201861
NPT2418	Cell Line	HCC1569	Homo sapiens	IC50	=	644.61	nM	10.6019/CHEMBL1201861
NPT2081	Cell Line	HCC1599	Homo sapiens	IC50	=	120.17	nM	10.6019/CHEMBL1201861
NPT2426	Cell Line	HCC1806	Homo sapiens	IC50	=	134.54	nM	10.6019/CHEMBL1201861
NPT2082	Cell Line	HT-144	Homo sapiens	IC50	=	23.75	nM	10.6019/CHEMBL1201861
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	36.02	nM	10.6019/CHEMBL1201861
NPT2083	Cell Line	KARPAS-422	Homo sapiens	IC50	=	907.39	nM	10.6019/CHEMBL1201861
NPT2084	Cell Line	KARPAS-45	Homo sapiens	IC50	=	2271.84	nM	10.6019/CHEMBL1201861
NPT2086	Cell Line	L-428	Homo sapiens	IC50	=	1157.78	nM	10.6019/CHEMBL1201861
NPT2087	Cell Line	L-540	Homo sapiens	IC50	=	95.14	nM	10.6019/CHEMBL1201861
NPT2070	Cell Line	LXF-289 cell line		IC50	=	55.37	nM	10.6019/CHEMBL1201861
NPT114	Cell Line	LoVo	Homo sapiens	IC50	=	430.68	nM	10.6019/CHEMBL1201861
NPT2430	Cell Line	M059J	Homo sapiens	IC50	=	100.6	nM	10.6019/CHEMBL1201861
NPT2072	Cell Line	MN-60	Homo sapiens	IC50	=	1263.32	nM	10.6019/CHEMBL1201861
NPT2088	Cell Line	MOLT-16	Homo sapiens	IC50	=	585.19	nM	10.6019/CHEMBL1201861
NPT2074	Cell Line	NCI-H1355	Homo sapiens	IC50	=	116.8	nM	10.6019/CHEMBL1201861
NPT2089	Cell Line	NCI-H1395	Homo sapiens	IC50	=	2234.83	nM	10.6019/CHEMBL1201861
NPT405	Cell Line	NCI-H226	Homo sapiens	IC50	=	777.21	nM	10.6019/CHEMBL1201861
NPT2090	Cell Line	SNU-16	Homo sapiens	IC50	=	6743.09	nM	10.6019/CHEMBL1201861
NPT2091	Cell Line	SNU-5	Homo sapiens	IC50	=	141.21	nM	10.6019/CHEMBL1201861
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	4071.59	nM	10.6019/CHEMBL1201861
NPT2093	Cell Line	PF-382	Homo sapiens	IC50	=	250.63	nM	10.6019/CHEMBL1201861
NPT2421	Cell Line	PFSK-1	Homo sapiens	IC50	=	5883.51	nM	10.6019/CHEMBL1201861
NPT2077	Cell Line	SCC-3	Homo sapiens	IC50	=	8.519	nM	10.6019/CHEMBL1201861
NPT2422	Cell Line	SCC-4	Homo sapiens	IC50	=	387.7	nM	10.6019/CHEMBL1201861
NPT2423	Cell Line	SCC-9	Homo sapiens	IC50	=	3787.53	nM	10.6019/CHEMBL1201861
NPT368	Cell Line	SN12C	Homo sapiens	IC50	=	3461.77	nM	10.6019/CHEMBL1201861
NPT392	Cell Line	SNB-75	Homo sapiens	IC50	=	303.46	nM	10.6019/CHEMBL1201861
NPT2424	Cell Line	T84	Homo sapiens	IC50	=	173.34	nM	10.6019/CHEMBL1201861
NPT1125	Cell Line	T98G	Homo sapiens	IC50	=	523.75	nM	10.6019/CHEMBL1201861
NPT2096	Cell Line	VA-ES-BJ	Homo sapiens	IC50	=	52.16	nM	10.6019/CHEMBL1201861
NPT2435	Cell Line	VM-CUB-1	Homo sapiens	IC50	=	260.82	nM	10.6019/CHEMBL1201861
NPT2097	Cell Line	EW-16	Homo sapiens	IC50	=	0.31	nM	10.6019/CHEMBL1201861
NPT2098	Cell Line	EW-18	Homo sapiens	IC50	=	3938.8	nM	10.6019/CHEMBL1201861
NPT1884	Cell Line	HCC1937	Homo sapiens	IC50	=	593.82	nM	10.6019/CHEMBL1201861
NPT2427	Cell Line	HCC1954	Homo sapiens	IC50	=	2281.19	nM	10.6019/CHEMBL1201861
NPT2428	Cell Line	HT-3	Homo sapiens	IC50	=	2.928	nM	10.6019/CHEMBL1201861
NPT2429	Cell Line	HT55	Homo sapiens	IC50	=	1954.57	nM	10.6019/CHEMBL1201861
NPT2099	Cell Line	KE-37	Homo sapiens	IC50	=	1.636	nM	10.6019/CHEMBL1201861
NPT2100	Cell Line	KG-1		IC50	=	597.14	nM	10.6019/CHEMBL1201861
NPT1358	Cell Line	LAMA-84	Homo sapiens	IC50	=	641.66	nM	10.6019/CHEMBL1201861
NPT2101	Cell Line	LAN-6	Homo sapiens	IC50	=	327.79	nM	10.6019/CHEMBL1201861
NPT387	Cell Line	M14	Homo sapiens	IC50	=	1337.6	nM	10.6019/CHEMBL1201861
NPT2102	Cell Line	MC-CAR	Homo sapiens	IC50	=	160.91	nM	10.6019/CHEMBL1201861
NPT112	Cell Line	MOLT-4	Homo sapiens	IC50	=	0.03248	nM	10.6019/CHEMBL1201861
NPT2104	Cell Line	NCI-H1417	Homo sapiens	IC50	=	236.9	nM	10.6019/CHEMBL1201861
NPT2105	Cell Line	NCI-H1436	Homo sapiens	IC50	=	1927.42	nM	10.6019/CHEMBL1201861
NPT2431	Cell Line	NCI-H1437	Homo sapiens	IC50	=	126.26	nM	10.6019/CHEMBL1201861
NPT370	Cell Line	NCI-H23	Homo sapiens	IC50	=	1206.61	nM	10.6019/CHEMBL1201861
NPT2432	Cell Line	NCI-H2342	Homo sapiens	IC50	=	62.51	nM	10.6019/CHEMBL1201861
NPT2092	Cell Line	NEC8	Homo sapiens	IC50	=	186.77	nM	10.6019/CHEMBL1201861
NPT2106	Cell Line	NH-12	Homo sapiens	IC50	=	139.13	nM	10.6019/CHEMBL1201861
NPT4611	Cell Line	PLC-PRF-5	Homo sapiens	IC50	=	4194.46	nM	10.6019/CHEMBL1201861
NPT2107	Cell Line	PSN1	Homo sapiens	IC50	=	2.554	nM	10.6019/CHEMBL1201861
NPT2109	Cell Line	SCH	Homo sapiens	IC50	=	1063771.62	nM	10.6019/CHEMBL1201861
NPT2110	Cell Line	SCLC-21H	Homo sapiens	IC50	=	963.03	nM	10.6019/CHEMBL1201861
NPT4612	Cell Line	SNG-M	Homo sapiens	IC50	=	134.17	nM	10.6019/CHEMBL1201861
NPT890	Cell Line	SNU-387	Homo sapiens	IC50	=	2934.67	nM	10.6019/CHEMBL1201861
NPT2433	Cell Line	SNU-423	Homo sapiens	IC50	=	1521.81	nM	10.6019/CHEMBL1201861
NPT2095	Cell Line	TALL-1	Homo sapiens	IC50	=	2395.5	nM	10.6019/CHEMBL1201861
NPT2434	Cell Line	TCC-SUP	Homo sapiens	IC50	=	481.7	nM	10.6019/CHEMBL1201861
NPT2112	Cell Line	TE-1	Homo sapiens	IC50	=	165.38	nM	10.6019/CHEMBL1201861
NPT2436	Cell Line	VMRC-RCZ	Homo sapiens	IC50	=	198.77	nM	10.6019/CHEMBL1201861
NPT1653	Cell Line	WM-115	Homo sapiens	IC50	=	84237.74	nM	10.6019/CHEMBL1201861
NPT2113	Cell Line	EW-24	Homo sapiens	IC50	=	782.97	nM	10.6019/CHEMBL1201861
NPT2115	Cell Line	HCC2157	Homo sapiens	IC50	=	726.85	nM	10.6019/CHEMBL1201861
NPT2116	Cell Line	HCC2218	Homo sapiens	IC50	=	588.82	nM	10.6019/CHEMBL1201861
NPT2438	Cell Line	HTC-C3	Homo sapiens	IC50	=	5789.44	nM	10.6019/CHEMBL1201861
NPT2117	Cell Line	HuTu80	Homo sapiens	IC50	=	4.83	nM	10.6019/CHEMBL1201861
NPT2118	Cell Line	KGN	Homo sapiens	IC50	=	207.13	nM	10.6019/CHEMBL1201861
NPT2120	Cell Line	LB1047-RCC	Homo sapiens	IC50	=	13.6	nM	10.6019/CHEMBL1201861
NPT2121	Cell Line	LB2241-RCC	Homo sapiens	IC50	=	13.19	nM	10.6019/CHEMBL1201861
NPT2439	Cell Line	MC-IXC	Homo sapiens	IC50	=	0.638	nM	10.6019/CHEMBL1201861
NPT2122	Cell Line	MC116	Homo sapiens	IC50	=	1416.64	nM	10.6019/CHEMBL1201861
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	IC50	=	72.35	nM	10.6019/CHEMBL1201861
NPT2123	Cell Line	MPP-89	Homo sapiens	IC50	=	991.22	nM	10.6019/CHEMBL1201861
NPT2124	Cell Line	MRK-nu-1	Homo sapiens	IC50	=	110.25	nM	10.6019/CHEMBL1201861
NPT2125	Cell Line	NCI-H1522	Homo sapiens	IC50	=	3235.46	nM	10.6019/CHEMBL1201861
NPT2440	Cell Line	NCI-H1563	Homo sapiens	IC50	=	1427.84	nM	10.6019/CHEMBL1201861
NPT2449	Cell Line	NCI-H1573	Homo sapiens	IC50	=	1460.85	nM	10.6019/CHEMBL1201861
NPT2441	Cell Line	NCI-H2347	Homo sapiens	IC50	=	849.97	nM	10.6019/CHEMBL1201861
NPT2442	Cell Line	NCI-H2405	Homo sapiens	IC50	=	294.34	nM	10.6019/CHEMBL1201861
NPT2450	Cell Line	NCI-H2452	Homo sapiens	IC50	=	8936.28	nM	10.6019/CHEMBL1201861
NPT2126	Cell Line	NKM-1	Homo sapiens	IC50	=	7.831	nM	10.6019/CHEMBL1201861
NPT2127	Cell Line	NMC-G1	Homo sapiens	IC50	=	216.75	nM	10.6019/CHEMBL1201861
NPT2108	Cell Line	QIMR-WIL	Homo sapiens	IC50	=	119.58	nM	10.6019/CHEMBL1201861
NPT2128	Cell Line	RCC10RGB	Homo sapiens	IC50	=	1349.36	nM	10.6019/CHEMBL1201861
NPT2111	Cell Line	SF-126	Homo sapiens	IC50	=	1405.65	nM	10.6019/CHEMBL1201861
NPT395	Cell Line	SF-268	Homo sapiens	IC50	=	170.86	nM	10.6019/CHEMBL1201861
NPT2443	Cell Line	SNU-449	Homo sapiens	IC50	=	3362.09	nM	10.6019/CHEMBL1201861
NPT4613	Cell Line	SNU-475	Homo sapiens	IC50	=	813.14	nM	10.6019/CHEMBL1201861
NPT2129	Cell Line	SNU-C1	Homo sapiens	IC50	=	1914	nM	10.6019/CHEMBL1201861
NPT2130	Cell Line	TE-10	Homo sapiens	IC50	=	72.6	nM	10.6019/CHEMBL1201861
NPT2131	Cell Line	WSU-NHL	Homo sapiens	IC50	=	192.04	nM	10.6019/CHEMBL1201861
NPT2444	Cell Line	YAPC	Homo sapiens	IC50	=	4367.51	nM	10.6019/CHEMBL1201861
NPT2114	Cell Line	EW-3	Homo sapiens	IC50	=	61.95	nM	10.6019/CHEMBL1201861
NPT4614	Cell Line	EW-7	Homo sapiens	IC50	=	12.14	nM	10.6019/CHEMBL1201861
NPT2132	Cell Line	EOL1	Homo sapiens	IC50	=	162.39	nM	10.6019/CHEMBL1201861
NPT391	Cell Line	HCC 2998	Homo sapiens	IC50	=	160.13	nM	10.6019/CHEMBL1201861
NPT2446	Cell Line	HCC38	Homo sapiens	IC50	=	604.11	nM	10.6019/CHEMBL1201861
NPT402	Cell Line	Hs-578T	Homo sapiens	IC50	=	6203.02	nM	10.6019/CHEMBL1201861
NPT2447	Cell Line	HuCCT-1	Homo sapiens	IC50	=	903.51	nM	10.6019/CHEMBL1201861
NPT1229	Cell Line	Huh-7	Homo sapiens	IC50	=	3222.86	nM	10.6019/CHEMBL1201861
NPT2119	Cell Line	KINGS-1	Homo sapiens	IC50	=	8611.64	nM	10.6019/CHEMBL1201861
NPT2448	Cell Line	KLE	Homo sapiens	IC50	=	2982.24	nM	10.6019/CHEMBL1201861
NPT2134	Cell Line	LB2518-MEL	Homo sapiens	IC50	=	534.56	nM	10.6019/CHEMBL1201861
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	13.9	nM	10.6019/CHEMBL1201861
NPT2136	Cell Line	MDA-MB-134-VI	Homo sapiens	IC50	=	2158.6	nM	10.6019/CHEMBL1201861
NPT2463	Cell Line	MDA-MB-157	Homo sapiens	IC50	=	2192.54	nM	10.6019/CHEMBL1201861
NPT2137	Cell Line	MS-1	Homo sapiens	IC50	=	344.02	nM	10.6019/CHEMBL1201861
NPT2138	Cell Line	MSTO-211H	Homo sapiens	IC50	=	2823.69	nM	10.6019/CHEMBL1201861
NPT2139	Cell Line	NCI-H1581	Homo sapiens	IC50	=	906.74	nM	10.6019/CHEMBL1201861
NPT4615	Cell Line	NCI-H1618	Homo sapiens	IC50	=	117.76	nM	10.6019/CHEMBL1201861
NPT2451	Cell Line	NCI-H28	Homo sapiens	IC50	=	2435.24	nM	10.6019/CHEMBL1201861
NPT2452	Cell Line	NCI-H292		IC50	=	884.41	nM	10.6019/CHEMBL1201861
NPT2140	Cell Line	NOMO-1	Homo sapiens	IC50	=	151.41	nM	10.6019/CHEMBL1201861
NPT2141	Cell Line	NOS-1	Homo sapiens	IC50	=	1502.27	nM	10.6019/CHEMBL1201861
NPT2453	Cell Line	RCM-1	Homo sapiens	IC50	=	847.28	nM	10.6019/CHEMBL1201861
NPT2454	Cell Line	RD	Homo sapiens	IC50	=	1898.46	nM	10.6019/CHEMBL1201861
NPT399	Cell Line	SF-295	Homo sapiens	IC50	=	11.48	nM	10.6019/CHEMBL1201861
NPT374	Cell Line	SF-539	Homo sapiens	IC50	=	127.02	nM	10.6019/CHEMBL1201861
NPT2455	Cell Line	SNU-C2B	Homo sapiens	IC50	=	295.05	nM	10.6019/CHEMBL1201861
NPT385	Cell Line	SR	Homo sapiens	IC50	=	13.46	nM	10.6019/CHEMBL1201861
NPT2456	Cell Line	TE-11	Homo sapiens	IC50	=	91.77	nM	10.6019/CHEMBL1201861
NPT2144	Cell Line	TE-12	Homo sapiens	IC50	=	189.83	nM	10.6019/CHEMBL1201861
NPT2457	Cell Line	YKG-1	Homo sapiens	IC50	=	545	nM	10.6019/CHEMBL1201861
NPT2146	Cell Line	YT	Homo sapiens	IC50	=	463.33	nM	10.6019/CHEMBL1201861
NPT1216	Cell Line	FaDu	Homo sapiens	IC50	=	128.29	nM	10.6019/CHEMBL1201861
NPT2458	Cell Line	FTC-133	Homo sapiens	IC50	=	517.22	nM	10.6019/CHEMBL1201861
NPT2459	Cell Line	HCC70	Homo sapiens	IC50	=	694.33	nM	10.6019/CHEMBL1201861
NPT2460	Cell Line	HCE-4	Homo sapiens	IC50	=	57.94	nM	10.6019/CHEMBL1201861
NPT2461	Cell Line	HuO-3N1	Homo sapiens	IC50	=	6454.52	nM	10.6019/CHEMBL1201861
NPT2133	Cell Line	KM-H2	Homo sapiens	IC50	=	130.45	nM	10.6019/CHEMBL1201861
NPT386	Cell Line	KM12	Homo sapiens	IC50	=	1083.64	nM	10.6019/CHEMBL1201861
NPT2135	Cell Line	LB373-MEL-D	Homo sapiens	IC50	=	429.62	nM	10.6019/CHEMBL1201861
NPT2147	Cell Line	LB647-SCLC	Homo sapiens	IC50	=	336.08	nM	10.6019/CHEMBL1201861
NPT2148	Cell Line	LB771-HNC	Homo sapiens	IC50	=	779.74	nM	10.6019/CHEMBL1201861
NPT2464	Cell Line	MDA-MB-175-VII	Homo sapiens	IC50	=	3158.19	nM	10.6019/CHEMBL1201861
NPT82	Cell Line	MDA-MB-231	Homo sapiens	IC50	=	3239.64	nM	10.6019/CHEMBL1201861
NPT1649	Cell Line	MV4-11	Homo sapiens	IC50	=	1.732	nM	10.6019/CHEMBL1201861
NPT2149	Cell Line	MZ1-PC	Homo sapiens	IC50	=	450.11	nM	10.6019/CHEMBL1201861
NPT2465	Cell Line	NCI-H1623	Homo sapiens	IC50	=	1014.28	nM	10.6019/CHEMBL1201861
NPT2150	Cell Line	NCI-H1648	Homo sapiens	IC50	=	523.01	nM	10.6019/CHEMBL1201861
NPT388	Cell Line	NCI-H322M	Homo sapiens	IC50	=	1801.52	nM	10.6019/CHEMBL1201861
NPT2151	Cell Line	NCI-H345	Homo sapiens	IC50	=	4731.93	nM	10.6019/CHEMBL1201861
NPT2466	Cell Line	NCI-H358	Homo sapiens	IC50	=	276.26	nM	10.6019/CHEMBL1201861
NPT2152	Cell Line	NTERA-2-cl-D1	Homo sapiens	IC50	=	0.02213	nM	10.6019/CHEMBL1201861
NPT2477	Cell Line	NUGC-3	Homo sapiens	IC50	=	16.95	nM	10.6019/CHEMBL1201861
NPT2142	Cell Line	REH	Homo sapiens	IC50	=	2.548	nM	10.6019/CHEMBL1201861
NPT2467	Cell Line	RERF-LC-MS	Homo sapiens	IC50	=	1031.57	nM	10.6019/CHEMBL1201861
NPT2153	Cell Line	RH-1	Homo sapiens	IC50	=	49.57	nM	10.6019/CHEMBL1201861
NPT2154	Cell Line	SH-4	Homo sapiens	IC50	=	387.26	nM	10.6019/CHEMBL1201861
NPT2155	Cell Line	SHP77	Homo sapiens	IC50	=	1378.3	nM	10.6019/CHEMBL1201861
NPT2143	Cell Line	ST486	Homo sapiens	IC50	=	494.36	nM	10.6019/CHEMBL1201861
NPT2156	Cell Line	SU-DHL-1	Homo sapiens	IC50	=	8.609	nM	10.6019/CHEMBL1201861
NPT2157	Cell Line	SUP-T1	Homo sapiens	IC50	=	110.4	nM	10.6019/CHEMBL1201861
NPT2481	Cell Line	SW1088	Homo sapiens	IC50	=	4668.27	nM	10.6019/CHEMBL1201861
NPT2145	Cell Line	TE-15	Homo sapiens	IC50	=	73.7	nM	10.6019/CHEMBL1201861
NPT2158	Cell Line	TE-441-T	Homo sapiens	IC50	=	1602.76	nM	10.6019/CHEMBL1201861
NPT2159	Cell Line	TE-5	Homo sapiens	IC50	=	132.24	nM	10.6019/CHEMBL1201861
NPT2160	Cell Line	no-10	Homo sapiens	IC50	=	299.6	nM	10.6019/CHEMBL1201861
NPT2161	Cell Line	no-11	Homo sapiens	IC50	=	7742.02	nM	10.6019/CHEMBL1201861
NPT2468	Cell Line	G-361	Homo sapiens	IC50	=	123.93	nM	10.6019/CHEMBL1201861
NPT2469	Cell Line	G-401	Homo sapiens	IC50	=	634.47	nM	10.6019/CHEMBL1201861
NPT2470	Cell Line	G-402	Homo sapiens	IC50	=	85.92	nM	10.6019/CHEMBL1201861
NPT2162	Cell Line	HCE-T	Homo sapiens	IC50	=	371.53	nM	10.6019/CHEMBL1201861
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	1015.02	nM	10.6019/CHEMBL1201861
NPT148	Cell Line	HCT-15	Homo sapiens	IC50	=	464.62	nM	10.6019/CHEMBL1201861
NPT2471	Cell Line	HuP-T3	Homo sapiens	IC50	=	710.55	nM	10.6019/CHEMBL1201861
NPT2472	Cell Line	HuP-T4	Homo sapiens	IC50	=	108.1	nM	10.6019/CHEMBL1201861
NPT2485	Cell Line	IA-LM	Homo sapiens	IC50	=	108.63	nM	10.6019/CHEMBL1201861
NPT2163	Cell Line	KMOE-2	Homo sapiens	IC50	=	1624.13	nM	10.6019/CHEMBL1201861
NPT2164	Cell Line	KMS-12-PE	Homo sapiens	IC50	=	3827.88	nM	10.6019/CHEMBL1201861
NPT2166	Cell Line	LB831-BLC	Homo sapiens	IC50	=	816.08	nM	10.6019/CHEMBL1201861
NPT2473	Cell Line	MDA-MB-361	Homo sapiens	IC50	=	808.98	nM	10.6019/CHEMBL1201861
NPT2474	Cell Line	MDA-MB-415	Homo sapiens	IC50	=	723.95	nM	10.6019/CHEMBL1201861
NPT2488	Cell Line	MDA-MB-453	Homo sapiens	IC50	=	1079.17	nM	10.6019/CHEMBL1201861
NPT2168	Cell Line	MZ2-MEL	Homo sapiens	IC50	=	432.47	nM	10.6019/CHEMBL1201861
NPT1820	Cell Line	NCI-H1650	Homo sapiens	IC50	=	282.57	nM	10.6019/CHEMBL1201861
NPT2475	Cell Line	NCI-H1651	Homo sapiens	IC50	=	4.99	nM	10.6019/CHEMBL1201861
NPT2476	Cell Line	NCI-H441	Homo sapiens	IC50	=	17.6	nM	10.6019/CHEMBL1201861
NPT937	Cell Line	NCI-H446	Homo sapiens	IC50	=	12422.72	nM	10.6019/CHEMBL1201861
NPT2478	Cell Line	NY	Homo sapiens	IC50	=	657.39	nM	10.6019/CHEMBL1201861
NPT2479	Cell Line	OAW-28	Homo sapiens	IC50	=	440.65	nM	10.6019/CHEMBL1201861
NPT2170	Cell Line	RKO	Homo sapiens	IC50	=	125.29	nM	10.6019/CHEMBL1201861
NPT2171	Cell Line	SIG-M5	Homo sapiens	IC50	=	3.524	nM	10.6019/CHEMBL1201861
NPT2172	Cell Line	SIMA	Homo sapiens	IC50	=	241.42	nM	10.6019/CHEMBL1201861
NPT3467	Cell Line	SJRH30	Homo sapiens	IC50	=	1674.2	nM	10.6019/CHEMBL1201861
NPT2483	Cell Line	SW13	Homo sapiens	IC50	=	642.49	nM	10.6019/CHEMBL1201861
NPT2495	Cell Line	SW1417	Homo sapiens	IC50	=	1005.45	nM	10.6019/CHEMBL1201861
NPT2173	Cell Line	TE-6	Homo sapiens	IC50	=	893.67	nM	10.6019/CHEMBL1201861
NPT2174	Cell Line	TE-8	Homo sapiens	IC50	=	35.86	nM	10.6019/CHEMBL1201861
NPT2175	Cell Line	GAK	Homo sapiens	IC50	=	596.24	nM	10.6019/CHEMBL1201861
NPT2484	Cell Line	GAMG	Homo sapiens	IC50	=	428.21	nM	10.6019/CHEMBL1201861
NPT2176	Cell Line	HD-MY-Z	Homo sapiens	IC50	=	640.25	nM	10.6019/CHEMBL1201861
NPT2486	Cell Line	IGR-1	Homo sapiens	IC50	=	321.6	nM	10.6019/CHEMBL1201861
NPT458	Cell Line	IGROV-1	Homo sapiens	IC50	=	105.97	nM	10.6019/CHEMBL1201861
NPT2165	Cell Line	KNS-42	Homo sapiens	IC50	=	1092.39	nM	10.6019/CHEMBL1201861
NPT2178	Cell Line	KNS-81-FD	Homo sapiens	IC50	=	1594.46	nM	10.6019/CHEMBL1201861
NPT2167	Cell Line	LB996-RCC	Homo sapiens	IC50	=	17.68	nM	10.6019/CHEMBL1201861
NPT2179	Cell Line	LC-1F	Homo sapiens	IC50	=	862.33	nM	10.6019/CHEMBL1201861
NPT2180	Cell Line	LC-2-ad	Homo sapiens	IC50	=	0.2492	nM	10.6019/CHEMBL1201861
NPT784	Cell Line	MDA-MB-468	Homo sapiens	IC50	=	345.31	nM	10.6019/CHEMBL1201861
NPT1773	Cell Line	ME-180	Homo sapiens	IC50	=	40.11	nM	10.6019/CHEMBL1201861
NPT2169	Cell Line	MZ7-mel	Homo sapiens	IC50	=	332.56	nM	10.6019/CHEMBL1201861
NPT2489	Cell Line	MeWo	Homo sapiens	IC50	=	9552.33	nM	10.6019/CHEMBL1201861
NPT2491	Cell Line	NCI-H1693	Homo sapiens	IC50	=	899.63	nM	10.6019/CHEMBL1201861
NPT2183	Cell Line	NCI-H1694	Homo sapiens	IC50	=	415.28	nM	10.6019/CHEMBL1201861
NPT397	Cell Line	NCI-H460	Homo sapiens	IC50	=	6.452	nM	10.6019/CHEMBL1201861
NPT2184	Cell Line	NCI-H510A	Homo sapiens	IC50	=	402.82	nM	10.6019/CHEMBL1201861
NPT2492	Cell Line	OAW-42	Homo sapiens	IC50	=	89.42	nM	10.6019/CHEMBL1201861
NPT2185	Cell Line	OCI-AML2	Homo sapiens	IC50	=	1.886	nM	10.6019/CHEMBL1201861
NPT2186	Cell Line	RL	Homo sapiens	IC50	=	5436.57	nM	10.6019/CHEMBL1201861
NPT2494	Cell Line	RMG-I	Homo sapiens	IC50	=	3461.27	nM	10.6019/CHEMBL1201861
NPT2188	Cell Line	SJSA-1	Homo sapiens	IC50	=	131.56	nM	10.6019/CHEMBL1201861
NPT4616	Cell Line	SK-CO-1	Homo sapiens	IC50	=	201.81	nM	10.6019/CHEMBL1201861
NPT2496	Cell Line	SW1463	Homo sapiens	IC50	=	2081.69	nM	10.6019/CHEMBL1201861
NPT1577	Cell Line	SW1573	Homo sapiens	IC50	=	144.68	nM	10.6019/CHEMBL1201861
NPT2189	Cell Line	TE-9	Homo sapiens	IC50	=	500.49	nM	10.6019/CHEMBL1201861
NPT2190	Cell Line	GB-1	Homo sapiens	IC50	=	452.18	nM	10.6019/CHEMBL1201861
NPT2191	Cell Line	GCIY	Homo sapiens	IC50	=	410.99	nM	10.6019/CHEMBL1201861
NPT2177	Cell Line	HDLM-2	Homo sapiens	IC50	=	1460.1	nM	10.6019/CHEMBL1201861
NPT2497	Cell Line	HEC-1	Homo sapiens	IC50	=	698.24	nM	10.6019/CHEMBL1201861
NPT2193	Cell Line	IM-9	Homo sapiens	IC50	=	56.22	nM	10.6019/CHEMBL1201861
NPT2194	Cell Line	IMR-5	Homo sapiens	IC50	=	0.3076	nM	10.6019/CHEMBL1201861
NPT4617	Cell Line	IPC-298	Homo sapiens	IC50	=	1228.41	nM	10.6019/CHEMBL1201861
NPT2498	Cell Line	KOSC-2	Homo sapiens	IC50	=	1531.03	nM	10.6019/CHEMBL1201861
NPT2499	Cell Line	KP-4	Homo sapiens	IC50	=	93.15	nM	10.6019/CHEMBL1201861
NPT2195	Cell Line	LC4-1	Homo sapiens	IC50	=	1239.59	nM	10.6019/CHEMBL1201861
NPT2500	Cell Line	LCLC-103H cell line		IC50	=	460.87	nM	10.6019/CHEMBL1201861
NPT2512	Cell Line	LCLC-97TM1	Homo sapiens	IC50	=	138.72	nM	10.6019/CHEMBL1201861
NPT2181	Cell Line	MEG-01	Homo sapiens	IC50	=	683.36	nM	10.6019/CHEMBL1201861
NPT2501	Cell Line	MEL-HO	Homo sapiens	IC50	=	39.4	nM	10.6019/CHEMBL1201861
NPT2502	Cell Line	MEL-JUSO	Homo sapiens	IC50	=	51.25	nM	10.6019/CHEMBL1201861
NPT2182	Cell Line	Mo	Homo sapiens	IC50	=	8911.63	nM	10.6019/CHEMBL1201861
NPT623	Cell Line	NALM-6	Homo sapiens	IC50	=	1.066	nM	10.6019/CHEMBL1201861
NPT2503	Cell Line	NCI-H1703	Homo sapiens	IC50	=	276.88	nM	10.6019/CHEMBL1201861
NPT4618	Cell Line	NCI-H1734	Homo sapiens	IC50	=	136.85	nM	10.6019/CHEMBL1201861
NPT2504	Cell Line	NCI-H1755	Homo sapiens	IC50	=	5436.94	nM	10.6019/CHEMBL1201861
NPT2505	Cell Line	NCI-H520		IC50	=	168.65	nM	10.6019/CHEMBL1201861
NPT455	Cell Line	NCI-H522	Homo sapiens	IC50	=	169.45	nM	10.6019/CHEMBL1201861
NPT2198	Cell Line	NCI-H524	Homo sapiens	IC50	=	2703.2	nM	10.6019/CHEMBL1201861
NPT2199	Cell Line	OCUB-M	Homo sapiens	IC50	=	102.98	nM	10.6019/CHEMBL1201861
NPT2336	Cell Line	OE19	Homo sapiens	IC50	=	364.96	nM	10.6019/CHEMBL1201861
NPT2506	Cell Line	RO82-W-1	Homo sapiens	IC50	=	13327.4	nM	10.6019/CHEMBL1201861
NPT2507	Cell Line	RPMI-2650	Homo sapiens	IC50	=	195.75	nM	10.6019/CHEMBL1201861
NPT1086	Cell Line	SK-HEP1	Homo sapiens	IC50	=	645.66	nM	10.6019/CHEMBL1201861
NPT2201	Cell Line	SK-LMS-1	Homo sapiens	IC50	=	439.29	nM	10.6019/CHEMBL1201861
NPT311	Cell Line	SK-LU-1	Homo sapiens	IC50	=	2.217	nM	10.6019/CHEMBL1201861
NPT2508	Cell Line	SW1710	Homo sapiens	IC50	=	72.58	nM	10.6019/CHEMBL1201861
NPT2509	Cell Line	SW1783	Homo sapiens	IC50	=	38.58	nM	10.6019/CHEMBL1201861
NPT2202	Cell Line	TGBC1TKB	Homo sapiens	IC50	=	1211.41	nM	10.6019/CHEMBL1201861
NPT2339	Cell Line	TGBC24TKB	Homo sapiens	IC50	=	710	nM	10.6019/CHEMBL1201861
NPT2510	Cell Line	GCT	Homo sapiens	IC50	=	4604.7	nM	10.6019/CHEMBL1201861
NPT2203	Cell Line	GDM-1	Homo sapiens	IC50	=	377.46	nM	10.6019/CHEMBL1201861
NPT2192	Cell Line	HEL	Homo sapiens	IC50	=	35.8	nM	10.6019/CHEMBL1201861
NPT2511	Cell Line	HGC-27	Homo sapiens	IC50	=	49.29	nM	10.6019/CHEMBL1201861
NPT2205	Cell Line	IST-MEL1	Homo sapiens	IC50	=	1.684	nM	10.6019/CHEMBL1201861
NPT2206	Cell Line	IST-MES1	Homo sapiens	IC50	=	4146.21	nM	10.6019/CHEMBL1201861
NPT2207	Cell Line	KP-N-YN	Homo sapiens	IC50	=	3415.35	nM	10.6019/CHEMBL1201861
NPT2208	Cell Line	KP-N-YS	Homo sapiens	IC50	=	640.12	nM	10.6019/CHEMBL1201861
NPT2513	Cell Line	LK-2	Homo sapiens	IC50	=	358.14	nM	10.6019/CHEMBL1201861
NPT2514	Cell Line	LN-405	Homo sapiens	IC50	=	2154.28	nM	10.6019/CHEMBL1201861
NPT2844	Cell Line	MES-SA	Homo sapiens	IC50	=	144.94	nM	10.6019/CHEMBL1201861
NPT2515	Cell Line	MFE-280	Homo sapiens	IC50	=	8348.73	nM	10.6019/CHEMBL1201861
NPT3882	Cell Line	MFE-296	Homo sapiens	IC50	=	286.23	nM	10.6019/CHEMBL1201861
NPT2196	Cell Line	NB1	Homo sapiens	IC50	=	186.61	nM	10.6019/CHEMBL1201861
NPT2210	Cell Line	NB10	Homo sapiens	IC50	=	81.65	nM	10.6019/CHEMBL1201861
NPT2211	Cell Line	NB12	Homo sapiens	IC50	=	1203.71	nM	10.6019/CHEMBL1201861
NPT2197	Cell Line	NCI-H1770	Homo sapiens	IC50	=	342.65	nM	10.6019/CHEMBL1201861
NPT1669	Cell Line	NCI-H1792	Homo sapiens	IC50	=	697.34	nM	10.6019/CHEMBL1201861
NPT2334	Cell Line	NCI-H1793	Homo sapiens	IC50	=	1814.82	nM	10.6019/CHEMBL1201861
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	500	nM	23501113
NPT148	Cell Line	HCT-15	Homo sapiens	GI	=	76	%	23584541
NPT1171	Cell Line	HEp-2	Homo sapiens	GI	=	68	%	23584541
NPT2	Others	Unspecified		Activity	=	32	%	23867164
NPT83	Cell Line	MCF7	Homo sapiens	GI	=	82	%	23811086
NPT81	Cell Line	A549	Homo sapiens	GI	=	70	%	23811086
NPT515	Cell Line	SGC-7901	Homo sapiens	IC50	=	2050	nM	23999045
NPT2	Others	Unspecified		IC50	=	1680	nM	23999045
NPT471	Organism	Trypanosoma brucei brucei	Trypanosoma brucei brucei	IC50	=	1000	nM	23927763
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	2000	nM	24056146
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	1500	nM	24056146
NPT2	Others	Unspecified		GI	=	65	%	24332623
NPT82	Cell Line	MDA-MB-231	Homo sapiens	EC50	=	103	nM	24436995
NPT82	Cell Line	MDA-MB-231	Homo sapiens	EC50	=	1250	nM	24436995
NPT370	Cell Line	NCI-H23	Homo sapiens	IC50	=	2000	nM	23792352
NPT2	Others	Unspecified		Potency		891.3	nM	PubChem BioAssay data set
NPT153	Individual Protein	Androgen Receptor	Homo sapiens	Potency		13333.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		10590.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		29849.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		23914.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		1883.4	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		2371	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		2238.7	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		1333.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		13332.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		33491.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		16784.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		6682.4	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		6309.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		375.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		21313.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		2683.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		3	nM	PubChem BioAssay data set
NPT49	Individual Protein	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	Potency		35481.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		8.4	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		23710.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		16785.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		42.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		29847	nM	PubChem BioAssay data set
NPT106	Individual Protein	Peroxisome proliferator-activated receptor delta	Homo sapiens	Potency		33488.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		21130	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		2511.9	nM	PubChem BioAssay data set
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	1500	nM	10.1039/C3MD00055A
NPT1970	Cell Line	THP-1	Homo sapiens	IC50	=	1500	nM	10.1039/C3MD00055A
NPT81	Cell Line	A549	Homo sapiens	IC50	=	400	nM	10.1039/C3MD00055A
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	IZ	=	32	mm	96254
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	IZ	=	22.8	mm	96254
NPT137	Cell Line	L1210	Mus musculus	Activity	=	2	mg/kg	458799
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	-2.3	ug	874953
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0.1	ug	874953
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	-0.8	ug	874953
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0	ug	874953
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0.3	ug	874953
NPT2	Others	Unspecified		IC50	=	500	nM	24910974
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	3000	nM	24913558
NPT2	Others	Unspecified		IC50	=	3000	nM	24913558
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	3000	nM	24913558
NPT81	Cell Line	A549	Homo sapiens	IC50	=	450	nM	25442306
NPT2	Others	Unspecified		IC50	=	1500	nM	25176329
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	2000	nM	25176329
NPT1970	Cell Line	THP-1	Homo sapiens	IC50	=	100	nM	25259515
NPT81	Cell Line	A549	Homo sapiens	IC50	=	40	nM	25259515
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	200	nM	25259515
NPT2	Others	Unspecified		AC50		7950	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		AC50		281.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		AC50		12589.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		AC50		316.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		10000	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		142.83	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		2570.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		26603.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		5631.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		20000	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		5961.25	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		77.33	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		26832.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		13626.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		16930.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		8127.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		12054.82	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		995.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		101.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		12554.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50		13.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		AC50		8912.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		AC50		44668.4	nM	PubChem BioAssay data set
NPT885	Cell Line	PBL		Activity	=	226.1		26290401
NPT885	Cell Line	PBL		Activity	=	17.9	%	26290401
NPT885	Cell Line	PBL		Activity	=	1.6		26290401
NPT885	Cell Line	PBL		Activity	=	1.3		26290401
NPT885	Cell Line	PBL		Activity	=	123.5	%	26290401
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	410	nM	26541587
NPT396	Cell Line	T47D	Homo sapiens	IC50	=	16970	nM	26541587
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	2937	nM	26541587
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	1870	nM	26541587
NPT708	Cell Line	HuT78	Homo sapiens	IC50	=	66	nM	26541587
NPT148	Cell Line	HCT-15	Homo sapiens	IC50	=	578	nM	26541587
NPT148	Cell Line	HCT-15	Homo sapiens	IC50	=	303	nM	26541587
NPT148	Cell Line	HCT-15	Homo sapiens	Activity	=	96		26541587
NPT148	Cell Line	HCT-15	Homo sapiens	Activity	=	87		26541587
NPT2	Others	Unspecified		Activity	=	7.8	%	26541587
NPT399	Cell Line	SF-295	Homo sapiens	IC50	=	540	nM	26335269
NPT405	Cell Line	NCI-H226	Homo sapiens	IC50	=	580	nM	26335269
NPT374	Cell Line	SF-539	Homo sapiens	IC50	=	38	nM	26335269
NPT387	Cell Line	M14	Homo sapiens	IC50	=	470	nM	26335269
NPT784	Cell Line	MDA-MB-468	Homo sapiens	IC50	=	500	nM	26335269
NPT81	Cell Line	A549	Homo sapiens	EC50	=	5200	nM	26508550
NPT81	Cell Line	A549	Homo sapiens	IC50	=	1700	nM	26615890
NPT2	Others	Unspecified		IC50	=	1400	nM	26615890
NPT2	Others	Unspecified		IC50	=	500	nM	10.1039/C5MD00289C
NPT2	Others	Unspecified		IC50	=	200	nM	10.1039/C5MD00289C
NPT4619	Organism	Raoultella planticola	Raoultella planticola	IC50	=	1100	nM	27089214
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	IC50	=	900	nM	27089214
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IC50	=	900	nM	27089214
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IC50	=	1100	nM	27089214
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	IC50	=	300	nM	27089214
NPT4619	Organism	Raoultella planticola	Raoultella planticola	MBC	=	3.9	ug/ml	27089214
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	MBC	=	1.9	ug/ml	27089214
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MBC	=	1.9	ug/ml	27089214
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MBC	=	3.9	ug/ml	27089214
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MBC	=	0.9	ug/ml	27089214
NPT20	Organism	Candida albicans	Candida albicans	MIC	>	500	ug/ml	27089214
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1.9	ug/ml	27089214
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	3.9	ug/ml	27089214
NPT4619	Organism	Raoultella planticola	Raoultella planticola	MIC	=	1.9	ug/ml	27089214
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	MIC	=	0.9	ug/ml	27089214
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	1.9	ug/ml	27089214
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	0.45	ug/ml	27089214
NPT81	Cell Line	A549	Homo sapiens	IC50	=	500	nM	27089214
NPT2	Others	Unspecified		IC50	=	500	nM	27089214
NPT2	Others	Unspecified		Activity	=	2	%	27377862

Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

● The left chart: Distribution of similarity level between NPC139867 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	78
0.1-0.2	642
0.2-0.3	12616
0.3-0.4	13892
0.4-0.5	3257
0.5-0.6	390
0.6-0.7	13
0.7-0.8	0
0.8-0.85	0
0.85-0.9	0
0.9-0.95	1
0.95-1	0

Similarity Score	Similarity Level	Natural Product ID
0.9008	High Similarity	NPC315011
0.669	Remote Similarity	NPC473955
0.6338	Remote Similarity	NPC475987
0.6338	Remote Similarity	NPC313348
0.6268	Remote Similarity	NPC133089
0.6259	Remote Similarity	NPC473249
0.6222	Remote Similarity	NPC471261
0.619	Remote Similarity	NPC251884
0.6176	Remote Similarity	NPC13351
0.6127	Remote Similarity	NPC307165
0.6111	Remote Similarity	NPC314792
0.6071	Remote Similarity	NPC309525
0.6063	Remote Similarity	NPC471258
0.6029	Remote Similarity	NPC174463
0.5969	Remote Similarity	NPC87919
0.5968	Remote Similarity	NPC40663
0.5959	Remote Similarity	NPC471256
0.5954	Remote Similarity	NPC15413
0.5942	Remote Similarity	NPC11379
0.5923	Remote Similarity	NPC471259
0.5902	Remote Similarity	NPC236322
0.5891	Remote Similarity	NPC469895
0.5878	Remote Similarity	NPC271562
0.5874	Remote Similarity	NPC173173
0.5827	Remote Similarity	NPC230849
0.5821	Remote Similarity	NPC147238
0.5811	Remote Similarity	NPC477400
0.5778	Remote Similarity	NPC276995
0.5778	Remote Similarity	NPC76660
0.5769	Remote Similarity	NPC471260
0.5769	Remote Similarity	NPC265094
0.5753	Remote Similarity	NPC120335
0.575	Remote Similarity	NPC69374
0.575	Remote Similarity	NPC90476
0.5745	Remote Similarity	NPC471262
0.5738	Remote Similarity	NPC116231
0.5725	Remote Similarity	NPC209734
0.5724	Remote Similarity	NPC311244
0.5724	Remote Similarity	NPC324722
0.5724	Remote Similarity	NPC198644
0.5714	Remote Similarity	NPC315110
0.5714	Remote Similarity	NPC207820
0.5694	Remote Similarity	NPC247902
0.5694	Remote Similarity	NPC262880
0.5685	Remote Similarity	NPC478139
0.5685	Remote Similarity	NPC41162
0.5682	Remote Similarity	NPC241394
0.5664	Remote Similarity	NPC470654
0.5664	Remote Similarity	NPC470650
0.5664	Remote Similarity	NPC470653
0.5639	Remote Similarity	NPC176773
0.5625	Remote Similarity	NPC472162
0.5625	Remote Similarity	NPC471263
0.5621	Remote Similarity	NPC477399
0.5621	Remote Similarity	NPC477401
0.5606	Remote Similarity	NPC128303

Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC139867 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	75
0.1-0.2	263
0.2-0.3	2939
0.3-0.4	4735
0.4-0.5	1065
0.5-0.6	73
0.6-0.7	7
0.7-0.8	0
0.8-0.85	0
0.85-0.9	1
0.9-0.95	1
0.95-1	2

Similarity Score	Similarity Level	Drug ID	Developmental Stage
1.0	High Similarity	NPD1689	Approved
0.9554	High Similarity	NPD2132	Phase 3
0.9008	High Similarity	NPD2101	Approved
0.8527	High Similarity	NPD6077	Discontinued
0.6439	Remote Similarity	NPD961	Discontinued
0.6259	Remote Similarity	NPD7747	Phase 1
0.6259	Remote Similarity	NPD7746	Phase 1
0.6129	Remote Similarity	NPD3714	Approved
0.6129	Remote Similarity	NPD3713	Approved
0.6129	Remote Similarity	NPD3715	Approved
0.6014	Remote Similarity	NPD7739	Clinical (unspecified phase)
0.5971	Remote Similarity	NPD7623	Phase 3
0.5971	Remote Similarity	NPD7624	Clinical (unspecified phase)
0.5942	Remote Similarity	NPD2645	Approved
0.5902	Remote Similarity	NPD2682	Approved
0.5891	Remote Similarity	NPD2259	Approved
0.5891	Remote Similarity	NPD2258	Approved
0.587	Remote Similarity	NPD3159	Discontinued
0.5857	Remote Similarity	NPD1806	Approved
0.5852	Remote Similarity	NPD1376	Discontinued
0.5845	Remote Similarity	NPD3677	Clinical (unspecified phase)
0.5797	Remote Similarity	NPD1773	Discontinued
0.5714	Remote Similarity	NPD7196	Clinical (unspecified phase)
0.5695	Remote Similarity	NPD5725	Approved
0.56	Remote Similarity	NPD7634	Clinical (unspecified phase)

Structure

CID139867 OpenBabel06191715502D 24 27 0 0 1 0 0 0 0 0999 V2000 3.4205 -0.0472 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2528 2.3911 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8363 -0.4750 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0170 2.8732 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5205 0.4735 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0137 1.9227 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 -1.6595 0.0002 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 0.8369 1.4474 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5213 1.4460 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8360 0.4749 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6779 -0.0121 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6795 1.9329 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6587 0.9728 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 -0.3196 4.4848 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8224 1.4478 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 3.4222 1.9651 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6108 4.6791 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5013 0.4872 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.6770 -1.0518 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6804 2.9727 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.9531 5.1934 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.2972 2.2838 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.6165 3.5818 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 2 23 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 24 1 0 0 0 0 5 9 2 0 0 0 0 5 11 1 0 0 0 0 6 8 1 0 0 0 0 6 15 1 6 0 0 0 7 3 1 6 0 0 0 7 13 1 0 0 0 0 7 18 1 0 0 0 0 8 10 2 0 0 0 0 8 12 1 0 0 0 0 9 12 1 0 0 0 0 9 16 1 0 0 0 0 10 11 1 0 0 0 0 10 19 1 0 0 0 0 11 20 2 0 0 0 0 12 21 2 0 0 0 0 13 15 1 6 0 0 0 13 18 1 0 0 0 0 14 17 2 0 0 0 0 14 22 1 0 0 0 0 14 24 1 0 0 0 0 15 19 1 0 0 0 0 15 23 1 1 0 0 0 M END $$$$

External Identifiers

PubChem CID	5746
ChEMBL	CHEMBL105
ZINC

Physicochemical Properties

Molecular Weight:	334.13
ALogP:	-1.3382
MLogP:	2.12
XLogP:	-0.252
# Rotatable Bonds:	8
Polar Surface Area:	147.88
# H-Bond Aceptor:	9
# H-Bond Donor:	4
# Rings:	4
# Heavy Atoms:	24

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