Natural Product: NPC13713

Natural Product ID:  NPC13713
Common Name:   Oidiolactone D
IUPAC Name:  
Synonyms:   oidiolactone D
Molecular Formula:   C16H18O6
Standard InCHIKey:  GEOBAHFMJINOOY-OQMNTFJPSA-N
Standard InCHI:  InChI=1S/C16H18O6/c1-14-4-3-5-15(2)10(14)9(21-12(15)18)11-16(22-11)7(14)6-8(17)20-13(16)19/h6,9-11,13,19H,3-5H2,1-2H3/t9-,10+,11+,13+,14+,15-,16-/m0/s1
Canonical SMILES:  O=C1O[C@@H](O)[C@@]23C(=C1)[C@@]1(C)CCC[C@]4([C@@H]1[C@@H]([C@H]3O2)OC4=O)C
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO33130 oidiodendron truncata Species Myxotrichaceae Eukaryota PMID[10514300]

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT1234 Organism Chlorella fusca Chlorella fusca IZ = 1 mm 19182783
NPT19 Organism Escherichia coli Escherichia coli IZ = 0 mm 23819871
NPT1230 Organism Bacillus megaterium Bacillus megaterium IZ = 0 mm 23819871
NPT1232 Organism Eurotium repens Eurotium repens IZ = 1 mm 23819871
NPT1233 Organism Mycotypha microspora Mycotypha microspora IZ = 1 mm 23819871
NPT1231 Organism Microbotryum violaceum Microbotryum violaceum IZ = 1 mm 12713406

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC13713 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9533 High Similarity NPC469655
0.9533 High Similarity NPC469656
0.9533 High Similarity NPC474846
0.9444 High Similarity NPC222834
0.9279 High Similarity NPC58662
0.9159 High Similarity NPC180744
0.8938 High Similarity NPC53396
0.8938 High Similarity NPC478204
0.8938 High Similarity NPC98249
0.8938 High Similarity NPC469684
0.886 High Similarity NPC108581
0.886 High Similarity NPC478206
0.886 High Similarity NPC478205
0.886 High Similarity NPC284707
0.885 High Similarity NPC471816
0.8839 High Similarity NPC475966
0.8818 High Similarity NPC469370
0.875 High Similarity NPC472002
0.8739 High Similarity NPC253906
0.8673 High Similarity NPC478212
0.8661 High Similarity NPC247031
0.8661 High Similarity NPC132790
0.8661 High Similarity NPC97939
0.8661 High Similarity NPC100329
0.8649 High Similarity NPC478210
0.8609 High Similarity NPC473968
0.8584 High Similarity NPC194951
0.8584 High Similarity NPC12046
0.8584 High Similarity NPC269530
0.8571 High Similarity NPC235014
0.8571 High Similarity NPC478211
0.8547 High Similarity NPC268530
0.8547 High Similarity NPC154491
0.8547 High Similarity NPC251226
0.8509 High Similarity NPC157441
0.85 High Similarity NPC293112
0.8487 Intermediate Similarity NPC11895
0.8482 Intermediate Similarity NPC143706
0.8482 Intermediate Similarity NPC299590
0.8482 Intermediate Similarity NPC472534
0.8475 Intermediate Similarity NPC102822
0.8475 Intermediate Similarity NPC477046
0.8475 Intermediate Similarity NPC159456
0.8475 Intermediate Similarity NPC4021
0.8468 Intermediate Similarity NPC187435
0.8468 Intermediate Similarity NPC67321
0.8462 Intermediate Similarity NPC476529
0.8462 Intermediate Similarity NPC475775
0.8462 Intermediate Similarity NPC42673
0.8462 Intermediate Similarity NPC122971
0.8448 Intermediate Similarity NPC473590
0.8443 Intermediate Similarity NPC473593
0.843 Intermediate Similarity NPC470780
0.843 Intermediate Similarity NPC298841
0.843 Intermediate Similarity NPC42399
0.8417 Intermediate Similarity NPC81736
0.8417 Intermediate Similarity NPC172154
0.8407 Intermediate Similarity NPC478209
0.8403 Intermediate Similarity NPC170538
0.8393 Intermediate Similarity NPC94942
0.8393 Intermediate Similarity NPC38948
0.839 Intermediate Similarity NPC107338
0.839 Intermediate Similarity NPC109607
0.8378 Intermediate Similarity NPC478208
0.8378 Intermediate Similarity NPC102352
0.8378 Intermediate Similarity NPC469607
0.8362 Intermediate Similarity NPC478216
0.8362 Intermediate Similarity NPC179626
0.8361 Intermediate Similarity NPC473620
0.8348 Intermediate Similarity NPC49451
0.8348 Intermediate Similarity NPC25909
0.8348 Intermediate Similarity NPC477126
0.8348 Intermediate Similarity NPC51978
0.8347 Intermediate Similarity NPC198209
0.8347 Intermediate Similarity NPC473635
0.8333 Intermediate Similarity NPC67251
0.8333 Intermediate Similarity NPC469789
0.8333 Intermediate Similarity NPC469382
0.8333 Intermediate Similarity NPC201992
0.8319 Intermediate Similarity NPC206618
0.8305 Intermediate Similarity NPC477071
0.8305 Intermediate Similarity NPC161065
0.8305 Intermediate Similarity NPC475041
0.8305 Intermediate Similarity NPC230513
0.8304 Intermediate Similarity NPC144854
0.8304 Intermediate Similarity NPC3316
0.8304 Intermediate Similarity NPC230541
0.8293 Intermediate Similarity NPC476851
0.8276 Intermediate Similarity NPC117712
0.8273 Intermediate Similarity NPC295791
0.8273 Intermediate Similarity NPC476081
0.8264 Intermediate Similarity NPC8369
0.8264 Intermediate Similarity NPC469790
0.8264 Intermediate Similarity NPC86346
0.8264 Intermediate Similarity NPC470922
0.8264 Intermediate Similarity NPC469379
0.8264 Intermediate Similarity NPC24651
0.8264 Intermediate Similarity NPC75856
0.8261 Intermediate Similarity NPC42658
0.8261 Intermediate Similarity NPC289312
0.8261 Intermediate Similarity NPC302146
0.8261 Intermediate Similarity NPC474516
0.8261 Intermediate Similarity NPC11252
0.8257 Intermediate Similarity NPC47024
0.825 Intermediate Similarity NPC312833
0.8246 Intermediate Similarity NPC472215
0.8246 Intermediate Similarity NPC5103
0.8246 Intermediate Similarity NPC472214
0.8235 Intermediate Similarity NPC241192
0.8235 Intermediate Similarity NPC48692
0.8235 Intermediate Similarity NPC112038
0.823 Intermediate Similarity NPC181994
0.823 Intermediate Similarity NPC277017
0.823 Intermediate Similarity NPC306265
0.823 Intermediate Similarity NPC192813
0.823 Intermediate Similarity NPC189075
0.823 Intermediate Similarity NPC154608
0.823 Intermediate Similarity NPC469916
0.823 Intermediate Similarity NPC325054
0.823 Intermediate Similarity NPC472439
0.823 Intermediate Similarity NPC275539
0.8226 Intermediate Similarity NPC476852
0.822 Intermediate Similarity NPC204552
0.822 Intermediate Similarity NPC188667
0.8214 Intermediate Similarity NPC127609
0.8211 Intermediate Similarity NPC476859
0.8211 Intermediate Similarity NPC270109
0.8205 Intermediate Similarity NPC474734
0.8205 Intermediate Similarity NPC474046
0.8205 Intermediate Similarity NPC96312
0.8205 Intermediate Similarity NPC328374
0.8205 Intermediate Similarity NPC138372
0.8205 Intermediate Similarity NPC152199
0.8205 Intermediate Similarity NPC259306
0.8205 Intermediate Similarity NPC302471
0.8205 Intermediate Similarity NPC235539
0.8205 Intermediate Similarity NPC251236
0.8205 Intermediate Similarity NPC106228
0.8205 Intermediate Similarity NPC470628
0.8205 Intermediate Similarity NPC207217
0.8205 Intermediate Similarity NPC134869
0.8205 Intermediate Similarity NPC40632
0.8198 Intermediate Similarity NPC61442
0.8197 Intermediate Similarity NPC225049
0.8197 Intermediate Similarity NPC203702
0.8197 Intermediate Similarity NPC120994
0.819 Intermediate Similarity NPC264153
0.819 Intermediate Similarity NPC75167
0.819 Intermediate Similarity NPC471204
0.819 Intermediate Similarity NPC311592
0.8182 Intermediate Similarity NPC27363
0.8182 Intermediate Similarity NPC105926
0.8182 Intermediate Similarity NPC265557
0.8182 Intermediate Similarity NPC91693
0.8182 Intermediate Similarity NPC475958
0.8182 Intermediate Similarity NPC18945
0.8174 Intermediate Similarity NPC188738
0.8167 Intermediate Similarity NPC204731
0.8167 Intermediate Similarity NPC67569
0.8167 Intermediate Similarity NPC470779
0.816 Intermediate Similarity NPC231240
0.816 Intermediate Similarity NPC93416
0.816 Intermediate Similarity NPC471855
0.8158 Intermediate Similarity NPC141350
0.8158 Intermediate Similarity NPC112457
0.8145 Intermediate Similarity NPC476854
0.8145 Intermediate Similarity NPC470851
0.8145 Intermediate Similarity NPC476966
0.8142 Intermediate Similarity NPC110496
0.8142 Intermediate Similarity NPC293512
0.8136 Intermediate Similarity NPC27999
0.8136 Intermediate Similarity NPC477116
0.8136 Intermediate Similarity NPC287343
0.8136 Intermediate Similarity NPC176513
0.8136 Intermediate Similarity NPC97908
0.8136 Intermediate Similarity NPC470775
0.8136 Intermediate Similarity NPC122033
0.8136 Intermediate Similarity NPC474654
0.8136 Intermediate Similarity NPC470854
0.8136 Intermediate Similarity NPC55296
0.8136 Intermediate Similarity NPC474483
0.8136 Intermediate Similarity NPC23046
0.813 Intermediate Similarity NPC179412
0.813 Intermediate Similarity NPC146456
0.813 Intermediate Similarity NPC469757
0.813 Intermediate Similarity NPC471356
0.813 Intermediate Similarity NPC117702
0.813 Intermediate Similarity NPC471357
0.8125 Intermediate Similarity NPC146731
0.8125 Intermediate Similarity NPC596
0.8125 Intermediate Similarity NPC296950
0.8125 Intermediate Similarity NPC477127
0.8125 Intermediate Similarity NPC258532
0.8125 Intermediate Similarity NPC65523
0.8125 Intermediate Similarity NPC283850
0.812 Intermediate Similarity NPC181145
0.812 Intermediate Similarity NPC474906
0.812 Intermediate Similarity NPC472274
0.812 Intermediate Similarity NPC18547
0.812 Intermediate Similarity NPC473798

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC13713 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.8482 Intermediate Similarity NPD4061 Clinical (unspecified phase)
0.8246 Intermediate Similarity NPD5955 Clinical (unspecified phase)
0.807 Intermediate Similarity NPD6686 Approved
0.8049 Intermediate Similarity NPD7507 Approved
0.8 Intermediate Similarity NPD7319 Approved
0.7982 Intermediate Similarity NPD5954 Clinical (unspecified phase)
0.7833 Intermediate Similarity NPD7115 Discovery
0.7759 Intermediate Similarity NPD5345 Clinical (unspecified phase)
0.7705 Intermediate Similarity NPD7516 Approved
0.7679 Intermediate Similarity NPD4225 Approved
0.7623 Intermediate Similarity NPD7327 Approved
0.7623 Intermediate Similarity NPD7328 Approved
0.7586 Intermediate Similarity NPD6008 Approved
0.7581 Intermediate Similarity NPD8513 Phase 3
0.7542 Intermediate Similarity NPD8132 Clinical (unspecified phase)
0.7522 Intermediate Similarity NPD7638 Approved
0.746 Intermediate Similarity NPD8328 Phase 3
0.7456 Intermediate Similarity NPD7639 Approved
0.7456 Intermediate Similarity NPD7640 Approved
0.744 Intermediate Similarity NPD8380 Approved
0.744 Intermediate Similarity NPD8516 Approved
0.744 Intermediate Similarity NPD8378 Approved
0.744 Intermediate Similarity NPD8379 Approved
0.744 Intermediate Similarity NPD8033 Approved
0.744 Intermediate Similarity NPD8517 Approved
0.744 Intermediate Similarity NPD8335 Approved
0.744 Intermediate Similarity NPD8515 Approved
0.744 Intermediate Similarity NPD8296 Approved
0.7422 Intermediate Similarity NPD8293 Discontinued
0.7398 Intermediate Similarity NPD8295 Clinical (unspecified phase)
0.7391 Intermediate Similarity NPD5344 Discontinued
0.7381 Intermediate Similarity NPD6370 Approved
0.7373 Intermediate Similarity NPD6412 Phase 2
0.7364 Intermediate Similarity NPD7736 Approved
0.736 Intermediate Similarity NPD8294 Approved
0.736 Intermediate Similarity NPD8377 Approved
0.7302 Intermediate Similarity NPD7503 Approved
0.7295 Intermediate Similarity NPD4632 Approved
0.7295 Intermediate Similarity NPD8133 Approved
0.7266 Intermediate Similarity NPD7492 Approved
0.7258 Intermediate Similarity NPD6009 Approved
0.7222 Intermediate Similarity NPD6319 Approved
0.7222 Intermediate Similarity NPD6059 Approved
0.7222 Intermediate Similarity NPD6054 Approved
0.7209 Intermediate Similarity NPD6616 Approved
0.7207 Intermediate Similarity NPD46 Approved
0.7207 Intermediate Similarity NPD6698 Approved
0.7165 Intermediate Similarity NPD6016 Approved
0.7165 Intermediate Similarity NPD6015 Approved
0.7154 Intermediate Similarity NPD7078 Approved
0.7143 Intermediate Similarity NPD6402 Approved
0.7143 Intermediate Similarity NPD7128 Approved
0.7143 Intermediate Similarity NPD5739 Approved
0.7143 Intermediate Similarity NPD6675 Approved
0.7109 Intermediate Similarity NPD5988 Approved
0.7107 Intermediate Similarity NPD6372 Approved
0.7107 Intermediate Similarity NPD6373 Approved
0.7083 Intermediate Similarity NPD5697 Approved
0.7083 Intermediate Similarity NPD5701 Approved
0.7073 Intermediate Similarity NPD6053 Discontinued
0.7073 Intermediate Similarity NPD6882 Approved
0.7073 Intermediate Similarity NPD8297 Approved
0.7034 Intermediate Similarity NPD7632 Discontinued
0.7031 Intermediate Similarity NPD6921 Approved
0.7025 Intermediate Similarity NPD6881 Approved
0.7025 Intermediate Similarity NPD7320 Approved
0.7025 Intermediate Similarity NPD6899 Approved
0.7009 Intermediate Similarity NPD6648 Approved
0.6992 Remote Similarity NPD6650 Approved
0.6992 Remote Similarity NPD6649 Approved
0.6992 Remote Similarity NPD8413 Clinical (unspecified phase)
0.6967 Remote Similarity NPD6014 Approved
0.6967 Remote Similarity NPD6012 Approved
0.6967 Remote Similarity NPD6013 Approved
0.6923 Remote Similarity NPD7604 Phase 2
0.6911 Remote Similarity NPD6883 Approved
0.6911 Remote Similarity NPD7290 Approved
0.6911 Remote Similarity NPD7102 Approved
0.6911 Remote Similarity NPD6371 Approved
0.6899 Remote Similarity NPD5983 Phase 2
0.6894 Remote Similarity NPD8074 Phase 3
0.6885 Remote Similarity NPD6011 Approved
0.6855 Remote Similarity NPD8130 Phase 1
0.6855 Remote Similarity NPD6617 Approved
0.6855 Remote Similarity NPD6869 Approved
0.6855 Remote Similarity NPD6847 Approved
0.6838 Remote Similarity NPD7902 Approved
0.6838 Remote Similarity NPD4755 Approved
0.6794 Remote Similarity NPD6067 Discontinued
0.6783 Remote Similarity NPD6399 Phase 3
0.6774 Remote Similarity NPD4634 Approved
0.6757 Remote Similarity NPD1694 Approved
0.6757 Remote Similarity NPD1733 Clinical (unspecified phase)
0.675 Remote Similarity NPD5211 Phase 2
0.6724 Remote Similarity NPD7748 Approved
0.6723 Remote Similarity NPD4700 Approved
0.6723 Remote Similarity NPD5286 Approved
0.6723 Remote Similarity NPD4696 Approved
0.6723 Remote Similarity NPD5285 Approved
0.672 Remote Similarity NPD6401 Clinical (unspecified phase)
0.6716 Remote Similarity NPD6033 Approved
0.6696 Remote Similarity NPD7515 Phase 2
0.6696 Remote Similarity NPD3618 Phase 1
0.6692 Remote Similarity NPD6336 Discontinued
0.6667 Remote Similarity NPD5328 Approved
0.6667 Remote Similarity NPD1698 Clinical (unspecified phase)
0.6667 Remote Similarity NPD7899 Clinical (unspecified phase)
0.6641 Remote Similarity NPD6274 Approved
0.6639 Remote Similarity NPD5141 Approved
0.6636 Remote Similarity NPD4752 Clinical (unspecified phase)
0.6612 Remote Similarity NPD5224 Approved
0.6612 Remote Similarity NPD5226 Approved
0.6612 Remote Similarity NPD5225 Approved
0.6612 Remote Similarity NPD4633 Approved
0.661 Remote Similarity NPD4697 Phase 3
0.6609 Remote Similarity NPD7838 Discovery
0.6581 Remote Similarity NPD7900 Approved
0.6581 Remote Similarity NPD7901 Clinical (unspecified phase)
0.6557 Remote Similarity NPD5174 Approved
0.6557 Remote Similarity NPD5175 Approved
0.6555 Remote Similarity NPD6084 Phase 2
0.6555 Remote Similarity NPD6083 Phase 2
0.6552 Remote Similarity NPD6079 Approved
0.6541 Remote Similarity NPD7642 Approved
0.6529 Remote Similarity NPD4159 Approved
0.6529 Remote Similarity NPD5223 Approved
0.6525 Remote Similarity NPD6356 Clinical (unspecified phase)
0.6518 Remote Similarity NPD6400 Clinical (unspecified phase)
0.6515 Remote Similarity NPD6291 Clinical (unspecified phase)
0.65 Remote Similarity NPD5696 Approved
0.65 Remote Similarity NPD8029 Clinical (unspecified phase)
0.6496 Remote Similarity NPD4202 Approved
0.6496 Remote Similarity NPD5778 Approved
0.6496 Remote Similarity NPD5779 Approved
0.6491 Remote Similarity NPD3573 Approved
0.6489 Remote Similarity NPD7101 Approved
0.6489 Remote Similarity NPD7100 Approved
0.6471 Remote Similarity NPD5222 Approved
0.6471 Remote Similarity NPD5220 Clinical (unspecified phase)
0.6471 Remote Similarity NPD5221 Approved
0.6462 Remote Similarity NPD6317 Approved
0.6452 Remote Similarity NPD4768 Approved
0.6452 Remote Similarity NPD4767 Approved
0.6449 Remote Similarity NPD7260 Phase 2
0.6423 Remote Similarity NPD4754 Approved
0.6418 Remote Similarity NPD7829 Approved
0.6418 Remote Similarity NPD7830 Approved
0.6417 Remote Similarity NPD5173 Approved
0.6412 Remote Similarity NPD6313 Approved
0.6412 Remote Similarity NPD6335 Approved
0.6412 Remote Similarity NPD6314 Approved
0.641 Remote Similarity NPD8035 Phase 2
0.641 Remote Similarity NPD6411 Approved
0.641 Remote Similarity NPD7983 Approved
0.641 Remote Similarity NPD8034 Phase 2
0.6403 Remote Similarity NPD6845 Suspended
0.6393 Remote Similarity NPD1700 Approved
0.6391 Remote Similarity NPD6909 Approved
0.6391 Remote Similarity NPD6908 Approved
0.6387 Remote Similarity NPD5695 Phase 3
0.6379 Remote Similarity NPD1695 Approved
0.6371 Remote Similarity NPD8170 Clinical (unspecified phase)
0.6349 Remote Similarity NPD5128 Approved
0.6349 Remote Similarity NPD4729 Approved
0.6349 Remote Similarity NPD4730 Approved
0.6348 Remote Similarity NPD7524 Approved
0.6339 Remote Similarity NPD3667 Approved
0.6325 Remote Similarity NPD3168 Discontinued
0.6303 Remote Similarity NPD5282 Discontinued
0.6303 Remote Similarity NPD6001 Approved
0.6271 Remote Similarity NPD5693 Phase 1
0.6271 Remote Similarity NPD7637 Suspended
0.6261 Remote Similarity NPD7146 Approved
0.6261 Remote Similarity NPD7334 Approved
0.6261 Remote Similarity NPD6684 Approved
0.6261 Remote Similarity NPD6409 Approved
0.6261 Remote Similarity NPD5330 Approved
0.6261 Remote Similarity NPD7521 Approved
0.6261 Remote Similarity NPD3574 Clinical (unspecified phase)
0.626 Remote Similarity NPD6868 Approved
0.625 Remote Similarity NPD5251 Approved
0.625 Remote Similarity NPD5250 Approved
0.625 Remote Similarity NPD5247 Approved
0.625 Remote Similarity NPD5248 Approved
0.625 Remote Similarity NPD5249 Phase 3
0.6239 Remote Similarity NPD5764 Clinical (unspecified phase)
0.6239 Remote Similarity NPD6101 Approved
0.6239 Remote Similarity NPD4753 Phase 2
0.6228 Remote Similarity NPD3666 Approved
0.6228 Remote Similarity NPD3665 Phase 1
0.6228 Remote Similarity NPD3133 Approved
0.6228 Remote Similarity NPD4786 Approved
0.6224 Remote Similarity NPD7966 Clinical (unspecified phase)
0.6204 Remote Similarity NPD8451 Approved
0.6202 Remote Similarity NPD5217 Approved
0.6202 Remote Similarity NPD5216 Approved
0.6202 Remote Similarity NPD5215 Approved
0.6174 Remote Similarity NPD7625 Phase 1
0.6174 Remote Similarity NPD7520 Clinical (unspecified phase)
0.6159 Remote Similarity NPD8448 Approved

Structure

External Identifiers

PubChem CID   10662409
ChEMBL   CHEMBL480668
ZINC  

Physicochemical Properties

Molecular Weight:  306.11
ALogP:  -0.6343
MLogP:  2.56
XLogP:  0.23
# Rotatable Bonds:  3
Polar Surface Area:  85.36
# H-Bond Aceptor:  6
# H-Bond Donor:  1
# Rings:  5
# Heavy Atoms:  22

Download Data

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General Info & Identifiers & Properties  
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