| Target ID | Target Name | Target Organism | # Natural Product | # Activity Record |
|---|---|---|---|---|
| NPT2761 | Phosphodiesterase 4A | Homo sapiens | 1 | 1 |
| NPT1537 | Phosphodiesterase 4 | Rattus norvegicus | 6 | 6 |
| NPT5222 | Phosphodiesterase 3B | Bos taurus | 2 | 4 |
| NPT1491 | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 | Rattus norvegicus | 2 | 2 |
| NPT5107 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Rattus norvegicus | 1 | 2 |
| NPT5107 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Rattus norvegicus | 1 | 2 |
| NPT5106 | Phosphodiesterase 10A | Homo sapiens | 1 | 11 |
| NPT5106 | Phosphodiesterase 10A | Homo sapiens | 1 | 11 |
| NPT5105 | Phosphodiesterase 3B | Homo sapiens | 1 | 2 |
| NPT5104 | Phosphodiesterase 3A | Homo sapiens | 2 | 4 |
| NPT5103 | Phosphodiesterase; PDE3 & PDE4 | Homo sapiens | 1 | 1 |
| NPT5101 | Phosphodiesterase 3A | Sus scrofa | 1 | 1 |
| NPT5100 | Phosphodiesterase 2A | Homo sapiens | 2 | 3 |
| NPT4698 | Phospholipase D1 | Homo sapiens | 2 | 4 |
| NPT4699 | Phospholipase D2 | Homo sapiens | 1 | 2 |
| NPT4102 | Phosphodiesterase 1 | Bos taurus | 4 | 4 |
| NPT1562 | Phosphodiesterase 1 | Rattus norvegicus | 4 | 5 |
| NPT5279 | Phosphodiesterase 7A | Homo sapiens | 1 | 1 |
| NPT5449 | PDE7B protein | Bos taurus | 1 | 2 |
| NPT860 | Phosphodiesterase 6C | Homo sapiens | 1 | 1 |
| NPT5464 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Crotalus adamanteus | 1 | 1 |
| NPT156 | Sphingomyelin phosphodiesterase | Homo sapiens | 97 | 97 |
| NPT4736 | Phosphodiesterase 9A | Homo sapiens | 2 | 2 |
| NPT4735 | Phosphodiesterase 4B | Homo sapiens | 6 | 6 |
| NPT3047 | Phosphodiesterase 1A | Homo sapiens | 1 | 1 |
| NPT1536 | Phosphodiesterase 5A | Rattus norvegicus | 4 | 5 |
| NPT5327 | Neutral sphingomyelinase | Homo sapiens | 2 | 2 |
| NPT6494 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | Homo sapiens | 1 | 1 |
| NPT6494 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | Homo sapiens | 1 | 1 |
| NPT6495 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 | Homo sapiens | 1 | 1 |
| NPT5447 | Phosphodiesterase 1A | Bos taurus | 1 | 1 |
| NPT5442 | Phosphodiesterase 2A | Bos taurus | 1 | 1 |
| NPT5440 | Phosphodiesterase 1B | Bos taurus | 1 | 1 |
| NPT5441 | Phosphodiesterase 1C | Homo sapiens | 1 | 1 |
| NPT50 | Tyrosyl-DNA phosphodiesterase 1 | Homo sapiens | 293 | 389 |
| NPT5439 | Phosphodiesterase 3 | Homo sapiens | 2 | 4 |
| NPT5438 | Heart phosphodiesterase | Bos taurus | 1 | 4 |
| NPT1464 | Phosphodiesterase 4D | Homo sapiens | 19 | 20 |
| NPT5099 | Phosphodiesterase 1 | Homo sapiens | 2 | 4 |
| NPT4418 | Autotaxin | Homo sapiens | 5 | 22 |
| NPT657 | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 | Bos taurus | 14 | 20 |
| NPT1563 | Phosphodiesterase 2A | Rattus norvegicus | 3 | 3 |
| NPT4907 | Tyrosyl-DNA phosphodiesterase 2 | Homo sapiens | 5 | 5 |
| NPT4581 | Phospholipase C-gamma-1 | Homo sapiens | 10 | 10 |
| NPT2560 | Phosphodiesterase 4 | Homo sapiens | 9 | 20 |
| NPT273 | Phosphodiesterase 5A | Homo sapiens | 20 | 20 |
| NPT4920 | Phospholipase C-beta-3 | Homo sapiens | 1 | 1 |