Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC123526 PPARD 1 33900 EC50 PMID: 22381047
NPC123526 PPARG 1 18900 EC50 PMID: 22381047
NPC131885 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC142319 TYR 2 Median: 130130
Range: 30260 to 230000
IC50 PMID: 16872137
PMID: 17693086
NPC193666 PPARG 1 48700 EC50 PMID: 22381047
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC255042 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC305518 MAPK1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC305518 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC305518 USP2 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 ALDH1A1 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 TP53 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 CYP2D6 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC45404 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC45404 ALDH1A1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 HPGD 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 KDM4E 2 Median: 13357.35
Range: 12589.3 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862