Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC123948 | NQO2 | 1 | 37100 | IC50 |
PMID: 11754615 |
| NPC161571 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | PMP22 | 1 | 42561.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | GAA | 1 | 39506.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | CYP1A1 | 1 | 34000 | IC50 |
PMID: 27265259 |
| NPC161571 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | ALDH1A1 | 4 |
Median: 37646 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | MAOB | 1 | 29370 | IC50 |
DOI: 10.1039/C3MD00376K |
| NPC161571 | BCR | 1 | 28000 | IC50 |
PMID: 16686543 |
| NPC161571 | CYP19A1 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 22115839 PMID: 22386564 |
| NPC161571 | SIRT1 | 3 |
Median: 46200 Range: 23600 to 87200 |
EC50 |
PMID: 18046409 PMID: 23316803 PMID: 23316803 |
| NPC161571 | KDM4E | 4 |
Median: 28370.85 Range: 22387.2 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | RELA | 1 | 20000 | IC50 |
Patent: Patent: US20130178536 A1 |
| NPC161571 | ODC1 | 1 | 19000 | IC50 |
PMID: 10075742 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | EPHX2 | 1 | 36400 | IC50 |
PMID: 26483136 |
| NPC254847 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | TP53 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | PTP4A3 | 2 |
Median: 31500 Range: 28000 to 35000 |
IC50 |
PMID: 22137788 PMID: 22137788 |
| NPC254847 | NPC1 | 1 | 20596.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | BRCA1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | USP2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ELANE | 1 | 18000 | IC50 |
PMID: 1578486 |
| NPC282923 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | PLEC | 2 |
Median: 93960.05 Range: 32104.8 to 155815.3 |
IC50 |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | ALDH1A1 | 2 |
Median: 33997.25 Range: 28183.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | THRB | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | CASP7 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | PTPN7 | 1 | 19620 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | BCHE | 1 | 17000 | IC50 |
PMID: 24568372 |
| NPC288089 | CASP1 | 5 |
Median: 25118.9 Range: 15848.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | ALOX12 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC296920 | PTGS1 | 1 | 25800 | IC50 |
PMID: 18487053 |
| NPC296920 | KDM4E | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC296920 | ALOX12 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC296920 | PTGS2 | 1 | 19600 | IC50 |
PMID: 18487053 |
| NPC312929 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | L3MBTL1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | PMP22 | 1 | 30131.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | ALDH1A1 | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | BLM | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | MTOR | 2 |
Median: 23280.9 Range: 23280.9 to 23280.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | KDM4E | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | SMN1;SMN2 | 3 |
Median: 25118.9 Range: 15848.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC46565 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC46565 | HPGD | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC46565 | TDP1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC46565 | MAPT | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC473411 | NQO2 | 1 | 15000 | IC50 |
DrugMatrix in vivo data: Hematology CHEMBL3885881 |
| NPC70622 | EPHX2 | 1 | 26800 | IC50 |
PMID: 26372074 |
| NPC82016 | NQO2 | 1 | 14600 | IC50 |
PMID: 23953689 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC254847 | TDP1 | 2 |
Median: 15186.05 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | CYP2D6 | 2 |
Median: 22106.05 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | ALDH1A1 | 2 |
Median: 13357.35 Range: 12589.3 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | MAPK1 | 2 |
Median: 11904.75 Range: 11220.2 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | KDM4E | 2 |
Median: 21154.6 Range: 14125.4 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | HSD17B10 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | LMNA | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC296920 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | HPGD | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | MYLK | 2 |
Median: 12000 Range: 12000 to 12000 |
IC50 |
PMID: 16441060 PMID: 18077363 |
| NPC46565 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC46565 | TP53 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |