Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC138299 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC138299 PLCG1 1 29000 IC50 PMID: 10869194
NPC138299 PLA2G2A 1 23800 IC50 PMID: 16504502
NPC138299 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC144939 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC144939 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 CYP2C9 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 CYP2C19 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 THRB 2 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 CARM1 1 25000 IC50 DOI: 10.1039/C1MD00199J
NPC178134 GSR 1 22800 IC50 PMID: 19015351
NPC178134 EPHX2 1 20700 IC50 PMID: 24679441
NPC178134 ATM 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 MAPK1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC280254 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC292366 NFE2L2 1 19080 EC50 PMID: 24053646
NPC76336 GLA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 GAA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 RECQL 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA13 1 17800 Ki PMID: 22892213
NPC178134 CA5B 1 12700 Ki PMID: 20185318
NPC178134 MAPT 8 Median: 21169.9
Range: 12589.3 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 TP53 2 Median: 22106.05
Range: 12589.3 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 KMT2A 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 CA3 1 10500 Ki PMID: 20185318
NPC280254 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA1 1 10560 Ki PMID: 22892213