Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC141765 | PPARD | 1 | 18110 | EC50 |
PMID: 27450788 |
| NPC141765 | PTPN1 | 1 | 15010 | IC50 |
PMID: 24224843 |
| NPC197316 | L3MBTL1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC298257 | MAPK1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC298257 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC306397 | SIRT5 | 1 | 46600 | IC50 |
PMID: 24900427 |
| NPC306397 | SIRT1 | 7 |
Median: 73000 Range: 25000 to 149000 |
IC50 |
PMID: 19700324 PMID: 23318905 PMID: 24900427 PMID: 25275824 PMID: 25549554 PMID: 26696402 DOI: 10.1039/C1MD00199J |
| NPC49074 | PTGS1 | 1 | 36000 | IC50 |
PMID: 16038536 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC64141 | MMP9 | 1 | 14280 | IC50 |
PMID: 22658537 |
| NPC76406 | PRKCA | 1 | 24400 | IC50 |
PMID: 9834166 |
| NPC86412 | L3MBTL1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC86412 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
| NPC64141 | MMP13 | 1 | 11090 | IC50 |
PMID: 22658537 |