Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC110396 MAPK1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110396 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 KDM4E 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 TP53 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC278556 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278556 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC291066 ALOX12 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC291066 CYP2A6 2 Median: 25001.725
Range: 25000 to 25003.45
IC50 PMID: 15658857
PMID: 19110342