Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC1075 CYP2C9 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC294902 HPGD 3 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 APEX1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 APP 1 32800 IC50 PMID: 22921742
NPC294902 AKR1B1 1 32000 IC50 PMID: 22236472
NPC294902 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 POLB 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC70744 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP19A1 1 48000 IC50 PMID: 16643058
NPC85813 F3 1 41000 IC50 PMID: 9834151
NPC85813 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC1075 KDM4E 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 THRB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 CA4 1 10100 Ki PMID: 20185318
NPC70744 CA3 1 11100 Ki PMID: 20185318
NPC70744 CA4 1 10800 Ki PMID: 20185318
NPC70744 CA5B 1 10500 Ki PMID: 20185318
NPC85813 FABP4 2 Median: 15650
Range: 13600 to 17700
IC50 PMID: 20471252
PMID: 25461324
NPC85813 PTGS1 1 13000 IC50 PMID: 16038536