Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC161571 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | PMP22 | 1 | 42561.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | GAA | 1 | 39506.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | CYP1A1 | 1 | 34000 | IC50 |
PMID: 27265259 |
| NPC161571 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | ALDH1A1 | 4 |
Median: 37646 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | MAOB | 1 | 29370 | IC50 |
DOI: 10.1039/C3MD00376K |
| NPC161571 | BCR | 1 | 28000 | IC50 |
PMID: 16686543 |
| NPC161571 | CYP19A1 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 22115839 PMID: 22386564 |
| NPC161571 | SIRT1 | 3 |
Median: 46200 Range: 23600 to 87200 |
EC50 |
PMID: 18046409 PMID: 23316803 PMID: 23316803 |
| NPC161571 | KDM4E | 4 |
Median: 28370.85 Range: 22387.2 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | RELA | 1 | 20000 | IC50 |
Patent: Patent: US20130178536 A1 |
| NPC161571 | ODC1 | 1 | 19000 | IC50 |
PMID: 10075742 |
| NPC34864 | L3MBTL1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | PMP22 | 1 | 30131.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | ALDH1A1 | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | BLM | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | MTOR | 2 |
Median: 23280.9 Range: 23280.9 to 23280.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | KDM4E | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | SMN1;SMN2 | 3 |
Median: 25118.9 Range: 15848.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC34864 | MYLK | 2 |
Median: 12000 Range: 12000 to 12000 |
IC50 |
PMID: 16441060 PMID: 18077363 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |